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Anatomy & Physiology 2 The endocrine system is the chemical control of your body (aka hormones) Endocrine glands are found throughout the body Hormones are chemicals that are made in one part of the body and affect another part of the body Two types: amino acidbased molecules or steroids Hormones affects target only certain tissues or organs – called target cells or target tissues The target cell or target tissue has a specific proteins that allows the hormone to attach to Negative feedback mechanisms in the blood are the primary means of controlling hormones This occurs three ways Hormonal stimulus: hormones trigger by other hormones; most “triggers” start in the hypothalamus in the brain This occurs three ways, continued: Humoral stimuli : fluids in the blood cause the release , example is the production of insulin Neural stimuli: nerve fibers trigger the release, example is adrenaline Major organs include: Pituitary, thyroid, parathyroid, adrenal, pinal, thymus, pancreas and gonads Hypothalamus is part of the nervous system, but also considered part of the endocrine as well Pituitary Gland Located in the brain and approximately the size of a grape Called the master gland because it makes hormones that regulate other glands Causes people to grow and onset of puberty Produces: tropic, growth, prolactin, adrenocorticotropic, thyroid-stimulating, thyrotropic, gonadotropic, folliclestimulating, lueteinizing, and interstitial cellstimulating hormones Thyroid Gland Found in your lower neck by the wind pipe Regulates your metabolism Parathyroid Glands Two lobes found near the thyroid gland Help control blood calcium levels and calcium absorption Adrenal glands Found over the top of the kidneys Helps to regulate mineral absorption, helps regulate blood pressure, helps regulate blood sugar and produces some sex hormones Pancreas Produces insulin, which regulates blood sugar If there is too much sugar in the blood in pushes the sugar out of the blood; if there is too little causes stored sugars to be releases Pinal gland Found in the brain Not much is known about this gland, but the “sleep trigger” appears to be here It also appears to inhibit sexual maturation until an adult size body is reached Thymus Located in the upper throat Large in infants and children, but decreases in size as we age Helps with growth and immunity Gonads Female gonads: ovaries Almond-sized and located in the pelvic cavity Produce estrogen and progesterone The rhythmic cycle of these two hormones cause the release of the ova and the secondary sex characteristics in females Gonads Male gonads: testes Located outside the body in the scrotum Produce androgens, which testosterone is the most important Testosterone cause the production of sperm and male sex characterisitics Placenta A temporary organ found in the uterus only during pregnancy Provides respiratory, excretory and nutrition delivery for the growing fetus, but also produces hormones necessary to maintain the pregnancy Placenta Produces human chorionic gonadotropin (hCG) hormone – this is what home pregnancy tests detect Also produces human placental lactogen to prepare breasts for lactation Also produces relaxin to loosen ligaments for childbirth Diabetes mellitus Goiters Graves’ Tumors disease