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Dru Ledder MS RD Nutrition Therapy for Cardiovascular Disorders  More than ½ the people who die in the US die from heart and blood vessel disease  75% of all hospitalized patients show symptoms of heart problems Nutritional Risk Factors in Heart Disease  Elevated cholesterol  Elevated triglycerides  Obesity  Hypertension  Generally poor eating habits and sedentary lifestyle Lipid Criteria Total Cholesterol  <200 mg/dL – Desirable  200-239 mg/dL: Borderline High  >240 mg/dL: High LDL Cholesterol – “Lousy” Cholesterol  - want these numbers Low  <100 mg/dL: optimal  100-129 mg/dL: Near optimal/above optimal  130-159 mg/dL: Borderline high  160-189 mg/dL: High  <190 mg/dL: Very high Lipid Criteria HDL Cholesterol – “Happy” Cholesterol  - want these numbers High  <40 mg/dL: Low  >60 mg/dL: High Triglycerides  <150 mg/dL: Normal  150-199 mg/dL: Borderline high  200-499 mg/dL: High  >500 mg/dL: Very high Nutrition Therapy for Cholesterol & Lipid Disorders Therapeutic Lifestyle Changes (TLC)  Saturated Fat - <7% of total calories  Polyunsaturated Fat – up to 10% of total calories  Monounsaturated Fat – Up to 20% of total calories  Total Fat: 25 – 35% of total calories  Carbohydrate: 50 – 60% of total calories  Fiber: 20 – 30 grams/day  Protein: 15% of total calories  Cholesterol: Less than 200 mg/day  Total Calories: Balance energy intake and expenditure to maintain desirable body weight/prevent weight gain Hypertension Criteria  Normal: <120/80  Pre-hypertension: 120/80 – 139/89  High blood pressure  Stage 1: 140/90 – 159/99  Stage 2: >160/100 Nutrition Therapy for Hypertension Dietary Approaches to Stop Hypertension (DASH) flexible and balanced eating plan that has been shown to lower high blood pressure  Research shows that the DASH eating plan lowers blood pressure. The plan:  Is low in saturated fat, cholesterol, and total fat  Focuses on fruits, vegetables, and fat-free or low-fat milk and milk products  Is rich in whole grains, fish, poultry, beans, seeds, and nuts  Contains fewer sweets, added sugars and sugary beverages, and red meats than the typical American diet DASH Guidelines           Total fat - 27% of calories Saturated fat - 6% of calories Protein - 18% of calories Carbohydrate - 55% of calories Cholesterol - 150 mg Sodium - 2,300 mg* (1,500 mg of sodium was a lower goal tested and found to be even better for lowering blood pressure) Potassium - 4,700 mg Calcium - 1,250 mg Magnesium - 500 mg Fiber - 30 g Class Activity  Fat & Sodium Explorer  http://www.americanheart.org/fatsandsodiumexplore r/explorer.html QUESTIONS??? Nutrition Therapy for Diabetes Data from the 2007 National Diabetes Fact Sheet (the most recent year for which data is available)  Total: 23.6 million children and adults in the United     States—7.8% of the population—have diabetes. Diagnosed: 17.9 million people Undiagnosed: 5.7 million people Pre-diabetes: 57 million people New Cases: 1.6 million new cases of diabetes are diagnosed in people aged 20 years and older each year. Types of Diabetes  Type 1 – Insulin dependent  Type 2 – Insulin Resistance  Gestational Diabetes  Pre Diabetes Diabetes – Risk Factors  Age: >60 years  Ethnicity: African-Americans, Native Americans, Pacific Islanders, Asian Americans  Genetics and family history  Obesity  History of gestational diabetes  Impaired glucose metabolism: prediabetes  Physical inactivity Diagnosing Diabetes Diabetes – Nutrition Assessment  Body weight, height, BMI  Waist circumference  Men >40 inches and women >35 inches shown increase in insulin resistance  Blood pressure  Lab work  Hemoglobin A1C  Fasting glucose  Urinary glucose  BUN & creatine  Lipid profile Diabetes – Nutrition Recommendations How the body uses CHO  Carbohydrate foods (grains, starches, fruit, sweets) break down to GLUCOSE  Protein foods (meats, nuts, beans) break down to AMINO ACIDS  Fat foods (oils, butter, margarine, avocado, bacon) break down to FATTY ACIDS.  CHO foods have greatest immediate influence of Blood Sugar Diabetes – Nutrition Recommendations Campfire illustration  CHO foods like kindling. Hot fire but goes out. Can result post meal burn out or lack of energy  Especially with insulin resistance can often result in low blood sugar after meals of primarily CHO  Low blood sugars result in craving sweets & starches  Headaches – usually resolved by eating  Protein & Fat are like the big logs that burn slow and make coals. Extends your energy.  Strive for a meal that has a mix of CHO foods, lean protein, healthy fats (ie. olive oil) Diabetes – Nutrition Recommendations Individualized Meal Plan      Calorie & CHO goal Exercise recommendations Coaching & support for behavior change Weight loss Additional factors for other health concerns  Sodium  Fats  Calcium/Magnesium/Potassium  Fluids/Fiber Diabetes – Nutrition Recommendations Survival Skills  3 meals per day and 2-3 snacks each day  Reading a food label, to find CHO content  Limit sugar in beverages, jello, candy, overt source of glucose etc.  Somewhat even distribution of CHO foods per meal throughout the day to help normalize blood sugars  Keep a food record for follow up visit and more detailed instruction and recommendations Joslin Diabetes Center Nutrition Guidelines  Carbohydrates - 40% of total caloric intake - total should not be less than 130 gm/day  Fiber - 20-35 gm  Fat - 30-35 % of total caloric intake  Saturated fat should be limited to < 10% of total caloric intake or < 7% in individuals with LDL-Cholesterol > 100 mg/dl  Polyunsaturated fat should comprise up to 10% of total calories  Monounsaturated fat up to 15-20% of total calories.  Protein 20-30% of total caloric intake Suggested Macronutrient Distribution According to Clinical Guidelines Diabetes Meal Planning  3 meals, and snacks as needed – depending on medications.  Meals:  Women/weight loss : 30-45 grams carbohydrate per meal (2-3 servings of carbohydrate)  Men/weight loss : 45 – 60 grams carbohydrate per meal (3-4 servings of carbohydrate)  Snacks  Women/weight loss: 0-15 grams carbohydrate per snack (0-1 servings carbohydrate)/ add protein or veggies  Men/weight loss: 0-30 grams carbohydrate per snack (12 servings carbohydrate)/add protein or veggies Diabetes Meal Planning - Sample Meal Plan  1800 calories/180 g CHO  Breakfast 500 calories/45 g CHO  Lunch 500 calories/45 g CHO  PM Snack 100 calories/30 g CHO  Supper 500 calories/45 g CHO  HS Snack 200 calories/15 g CHO or 3 CHO choice or 3 CHO choice or 2 CHO choice or 3 CHO choice or 1 CHO choice Class Activity Diabetes Risk Test http://www.diabetes.org/diabetesbasics/prevention/diabetes-risk-test/ QUESTIONS??? Liver  A normal liver regulates the proper digestion, metabloism, and absoprtion of food  Diseases of the liver can adversly affect gastrointestinal function and the use of food Nutrition Therapy for Hepatitis  Viral hepatitis - inflammation of the liver  The goal of nutrition management for hepatitis is to promote liver tissue healing Nutrition Therapy for Hepatitis  Protein: 1.2 – 1.5 grams/kg body weight/day  Carbohydrate: no restriction – monitor glucose and adjust      as necessary Fat: 30% of calories – restrictions only with maldigestion due to reduced synthesis and secretions of bile acids Calories: 25 – 35 kcal/kg body weight/day Multivitamin supplement at 100% RDAs/DRIs Fluid and sodium restriction if edema or ascites present If adequate nutrition cannot be maintained by oral feeding, enteral feedings or TPN may be indicated Nutrition Therapy for Cirrhosis  Cirrhosis is the final stage of certain liver injuries (alcoholism, untreated hepatitis, bilary obstruction, drug/poison ingestion)  Malnutrition, chronic acute hepatitis, and excessive intake of vitamin A can induce cirrhosis Nutrition Therapy for Cirrhosis  Protein: 75 – 100 grams/day (If hepatic coma is not indicated)  Sodium: Edema and/or ascites is counteracted 500 – 1000 mg sodium. Fluid intake may be limited  Texture  Esophageal varices present – semisolid or liquid diet to avoid potential rupture  Tube feedings not advised  Avoid coffee, tea, pepper, chili powder, or any other irritating seasonings  Patients with poor appetite  Oral nutritional supplements, vitamin/mineral supplements, electrolyte replacements, parenteral feedings QUESTIONS??? Gallbladder & Pancreas  Gallbladder function is to concentrate and store bile from the liver  When fat enters the duodenum, it stimulates the release of bile which helps emulsify fats so they can be broken down  When gallstones are present, they block the flow of pancreatic juices and pancreatitis can occur  Alcoholism can also cause pancreatitis Nutrition Therapy for Cholecystitis (inflammation of the gallbladder)  Chronic cholecystitis  Fat/calorie controlled diet  Adequate amounts of carbohydrates & fiber  Acute cholecystitis  Low fat diet  Decrease gas forming veggies  Fat soluble vitamins may need to be replaced  Cholecystectomy  Fat intake limited for several months  Introduce fats gradually Nutrition Therapy for Acute Pancreatitis  Goal is to prevent the secretion of pancreatic enzymes  Start NPO using TPN feedings  As healing progresses, the diet can progress  Clear liquid with amino acids, predigested fats  Bland diet in 6 small feedings  No stimulants Nutrition Therapy for Chronic Pancreatitis  Low fat diet  Vitamin and mineral supplementation – especially fat soluble vitamins (A, D, E, K), and B complex  Tube feedings or TPN may be necessary  No alchohol QUESTIONS??? Kidney Disease  2 kidneys  Each the size of your fist  One on each side of your spine  Weight 4-6 ounces each  Nephron - the basic functioning unit of the kidney  1 million per kidney 38 What do they do?  Remove waste products and extra fluid from the blood by forming urine  Keep blood chemicals in balance  Produce some of the body’s hormones to control anemia, blood pressure, and bone health 39 Diet with CKD – Early Stages  Protein: To restrict or not to restrict?  For persons in stages, 1, 2,3 – protein intake is often limited to 12-15% of each day’s calorie intake or to .8 grams/kg body weight.  Persons with Stage 4 CKD may be advised to reduce protein to 10% of calorie intake each day, which is .6.75 grams protein/kg body weight. 40 Phosphorus  Phosphorus restriction is recommended as soon as an elevated blood level is seen  Some experts think 800-1000mg of phosphorus daily is adequate 41 Potassium  If the level is high, a low potassium diet is prescribed. Restricting such foods as avocados, dried fruits (raisins, apricots, prunes), potatoes, oranges, bananas, and salt substitutes is often needed. 42 That was the early stages of CKD Any questions? 43 Treatment for Stage 5  A treatment for Stage 5 kidney disease  Blood is cleaned through filtration  a natural filter inside the body (peritoneal dialysis)  an artificial filter outside of the body (hemodialysis)  Dialysis must be done on a regular basis to replace kidney function 44 Types of treatment  Peritoneal dialysis  Hemodialysis  Transplant 45 Peritoneal Dialysis  Removes wastes and fluid  Catheter in the abdomen  Several exchanges daily 46 Hemodialysis  Blood circulates through a filter (dialyzer) to remove wastes and fluid  A machine controls speed and safety factors  Hemodialysis can be done in-center or at home, night or day  Traditional: At a dialysis facility  3 treatments/week - 3 to 4 hours each treatment 47 Medical Nutrition Therapy Calories  Protein  Fluids  Sodium  Potassium  Phosphorus  Calcium  Vitamins  48 Calories  Calorie requirements: 30 to 40 kcal/kg of actual or Adjusted BW/day  Adjusted to maintain, decrease, or increase actual body weight as desired  Individualized for carbohydrate, fat and cholesterol recommendations 49 Protein  Essential for growth, maintenance, preventing infection, and anemia  Important for wound healing and repair Protein Requirements  1.2 to 1.5 gm/kg Adjusted Body Weight per day  50% to 60% high biological value  Increased needs in catabolic states  Adequate calories for protein sparing 51 Sodium  Helps regulate body fluid volume and balance  Limiting sodium helps to prevent:  Excessive thirst  Fluid retention  Elevated blood pressure 52 Sodium Allowance  2.0 to 3.0 gm (2000 to 3000 mg)/day  May be higher for patients with residual renal function and those on peritoneal dialysis 53 Fluids  Fluid accumulates in the body between dialysis treatments  Interdialytic weight gain  3 to 5% of EDW  Excess fluid can cause:  Edema  Shortness of breath  Hypertension  Congestive heart failure 54 Fluid Allowance  1.0 to 1.5 liters per day  Includes all foods liquid at room temperature 55 Potassium  Mineral required for muscle contraction and nerve function  Goal:  Maintain levels between 3.5 and 5.5 mEq/L 56 Potassium  Symptoms of elevated potassium or hyperkalemia are:  Muscle weakness  Numbness and tingling of extremities  Decreasing pulse rate  Cardiac arrest 57 Potassium Allowance  2.0 to 3.0 gm (2000 to 3000 mg) per day  Based on lab values  Allowed more if residual renal function or on peritoneal dialysis 58 Phosphorus  Mineral widely available in many foods  85-90% found in bones & teeth  Vital to energy production and storage  Goal:  Maintain levels between 3.5 and 5.5 mg/dl 59 Phosphorus Allowance 800 – 1000 mg  ½ cup milk ~100 mg  1 ounce cheese 100 – 290 mg  ½ beans (pinto, lima) = 125 mg  3 ounces meat = 195 mg  1 ounce nuts = 120 mg  2 tablespoons peanut butter = 120 mg 60 Calcium  Mineral needed for:  healthy bones  muscle contraction & relaxation  proper nerve functioning  Goal:  Maintain level between 8.5 – 9.5 mg/dl 61 Calcium Allowance  2000 mg  Sources to limit:  Dairy products (milk, cheese, yogurt, ice cream)  Fortified foods  Medications 62 Nutrition and Renal-Related Laboratory Measures Healthy Stage 5 CKD BUN mg/dl <25 50 – 100 Creatinine mg/dl <1.6 10 – 18 Albumin g/dl >4.0 ≥4.0 14 – 18 11 – 12 >25 25 – 50 Ferritin ng/ml 12 – 300 100 – 500 Potassium mEq/l 3.5 – 5.0 3.5 – 5.5 Corrected Calcium mg/dl 8.5 – 10.5 8.4 – 9.5 Phosphorus mg/dl 2.5 – 4.5 3.5 – 5.5 <100 150 - 300 Hg g/dl Iron Saturation % Intact PTH pg/ml QUESTIONS??? References  Stanfield, P. & Hui, Y.H. (2010). Nutrition and Diet Therapy, Self-Instructional Approaches. Massachusetts: Jones and Bartlett Publishers.  Escott-Stump, S. (1997). Nutrition and Diagnosis Related Care. Lipincott Williams & Wilkins.  NHLBI DASH Eating Plan - http://www.nhlbi.nih.gov/health/dci/Diseases/dash/dash_ what.html  Joslin Dietary Guidelines http://www.joslin.org/docs/Nutrition_Guideline_Graded.p df  Erin Hetrick, MS, RD, LDN – Kaplan University Professor & Renal Dietitian