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Genetics—Branch of biology that studies heredity Heredity – the passing on of characteristics from parents to offspring Gregor Mendel--Austrian monk who used pea plants to study how traits are passed from one generation to the next Traits—characteristics that are inherited Hybrid—offspring of parents (pea plants) that have different forms of a trait Ex.—tall pea plant bred with short pea plant Mendel’s Experiment Cross-pollination—using pollen from one plant to pollinate a different plant Mendel bred tall pea plants with short plants The offspring in the 1st generation were all tall The offspring in the second generation were 75% tall and 25% short The short trait disappeared in the 1st generation and reappeared in the 2nd generation •P generation—original parents •F1 generation—offspring of the parent plants (filial) •Ex.Your parents are P and you are F1 P1 Short pea plant Tall pea plant F1 All tall pea plants F2 3 tall: 1 short Alleles—Different forms of the same gene, each one located on different copies of the same chromosome (1 from mother and 1 from father) Ex. T is allele for tall plant, t is allele for short plant •Dominant—trait that covers over another trait, capital letter •Ex. T (tall) is a dominant allele •Recessive—trait that is covered over by another trait, lower case letter •Ex. t (short) is the recessive allele T-tall t-short The second generation Pod color Pod Plant shape height purple axial (side) green inflated tall white terminal (tips) yellow constricted short Seed Seed Flower Flower shape color color position Dominant trait round yellow Recessive trait wrinkled green •Phenotype—physical appearance •Ex. Phenotype is tall •Genotype—genetic makeup •Ex. Genotype can be TT for a tall plant Tall pea plant •Homozygous—2 same alleles for a trait •Ex. TT-tall tt-short •Heterozygous—2 different alleles for a trait (carrier) •Ex. Tt-tall TT, Tt-tall tt-short Simple Genetic Human Traits Tongue Rolling (R) Dimples (D) Freckles (F) Eye Color: Brown is dominant to blue (B) Hitchhiker’s Thumb (h) Law of segregation—Each gene has 2 alleles for a trait, after meiosis each gamete receives one of these alleles Law of Independent assortment – genes for different traits are independently inherited of each other Punnett square--A tool used to predict the possible offspring of a cross between 2 parents Monohybrid cross--crossing a single trait between 2 parents Genotype of the parents along top and side of square Cross each trait individually 1. Cross TT x tt T T t Tt Tt t Tt Tt Genotypic ratio 100% Tt Phenotypic ratio 100% tall 2. Cross Tt x tt T t t Tt tt t Tt tt Genotypic ratio 50% Tt 50% tt 1 Tt : 1 tt Phenotypic ratio 50% tall 50% short 1 tall : 1 short 3. Cross Tt x TT T t T TT Tt T TT Tt Genotypic ratio 50% TT 50% Tt 1 TT : 1 Tt Phenotypic ratio 100% tall 4. Cross Tt x Tt T t T TT Tt t Tt tt Genotypic ratio 25% TT 50% Tt 25%tt 1 TT : 2 Tt : 1 tt Phenotypic ratio 75% tall 25% short 3 tall : 1 short Sex Chromosomes Female (eggs): XX Male (sperm): XY •Every time a female has a baby, what percent chance do they have of having a boy? A girl? •If a female has 5 boys in a row, what percent chance do they have to have another boy? A girl? •Which parent determines the sex of a baby? WHY?