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NUTRITION SCREENING & ASSESSMENT Dr Yahya Pasdar Kermanshah University of Medical Sciences [email protected] www.Drpasdar.com Nutritional Screening & Assessment Overall View Screening Assessment Available Tools Validity and Reliability Take Home Massage Nutrition Care Process Model Screening & Referral System Identify risk factors Use appropriate tools and methods Involve interdisciplinary collaboration Nutrition Assessment Obtain/collect timely and appropriate data Analyze/interpret with evidence- based standards Document Nutrition Diagnosis Identify and label problem Determine cause/contributing risk factors Cluster signs and symptoms/ defining characteristics Document Relationship Between Patient/Client/Group & Dietetics Professional Nutrition Monitoring and Evaluation Monitor progress Measure outcome indicators Evaluate outcomes Document Outcomes Management System Monitor the success of the Nutrition Care Process implementation Evaluate the impact with aggregate data Identify and analyze causes of less than optimal performance and outcomes Refine the use of the Nutrition Care Process Nutrition Intervention Plan nutrition intervention Formulate goals and determine a plan of action Implement the nutrition intervention Care is delivered and actions are carried out Document Effects of under-nutrition on organ function Ventilation - loss of muscle & hypoxic responses Psychology – depression & apathy Immunity – Increased risk of infection liver fatty change, functional decline necrosis, fibrosis Decreased cardiac output Renal function - loss of ability to excrete Na & H2O Impaired wound healing Hypothermia Impaired gut integrity and immunity Anorexia Loss of strength Malnutrition & cancer Immune functions Survival Malnutrition (60~85%) Response to chemotherapy Performance status Muscle function Quality of life 6 Van Cutsem et al., 2005 Mariette et al., 2012 The Malnutrition Carousel 28-34% of patients admitted to hospital are at risk of malnutrition Hospital Home More GP visits Longer stay More hospital admissions More support postdischarge More likely to be discharged to Care Homes Up to 70% of patients discharged from hospital weigh less than on admission Why do we need to identify malnutrition? Malnutrition is associated with: length of stay in hospital complications hospital costs mortality rates Screening vs Assessment Screening “Rapid, simple, general procedure done at first contact with subject to detect risk of malnutrition, done by nurses, doctors or other care workers” (Elia/ MAG 2003) Assessment “Detailed, more specific in depth evaluation of subject’s nutritional status, done by those with nutritional expertise” (Elia/ MAG 2003) Cancer patients are not all created equal…should we expect the impact of nutrition therapy to be the same across all patients? Why screen for malnutrition? Malnutrition is not always visible, is more common than you think and costs health and social care ≥£13b/year • At any one time, more than 3 million adults in UK are at risk • 93% live in the community & 2% are in hospital where ~1 in 3 are at risk on admission • Older people and those with chronic conditions are particularly at risk • Help people stay independent and well in their own home as long as possible & reduce the need for admission into hospital Why screen for malnutrition? • Effective management of malnutrition reduces the burden on health & care resources • Regular screening is the only way that malnourished individuals can be identified and appropriate action taken • Recommended / required by various bodies e.g NICE, NHSQIS, Council of Europe, Care Quality Commission, Nutrition Action Plan What is clinical concern? Unintentional weight loss, fragile skin, poor wound healing, apathy, wasted muscles, poor appetite, impaired swallowing, altered bowel habit, loose fitting clothes or prolonged inter-current illness. (NICE 2006) What is screening and how can we do it? Characteristics of Nutrition Screening Simple and easy to complete Routine data Cost effective Effective in identifying nutritional problems Reliable and valid Screening: Nutrition Care Indicators Nutritional history Feeding modality >10 lbs in past 3 months Serum Albumin Diagnosis TPN/PPN TF Diet restrictions Unintentional Weight Loss Appetite Nausea/vomiting (>3 days) Diarrhea Dysphagia Reduced food intake (<50% of normal for 5 days) Cachexia, end-stage liver or kidney disease, coma, malnutrition, decubitis ulcers, cancer of GI tract, Crohns, Cystic Fibrosis, new onset diabetes, eating disorder Above used to determine nutritional risk and need for referral to RD Nutrition Screening Tools Requirements quick and simple to administer sensitive enough to identify individuals at risk appropriate for client group being screened capable of being used by non-dietitians reproducible when used by different observers able to guide non dietetic staff into taking appropriate action for findings recorded Nutritional Screening Tools No single / standard way of assessing nutritional status Various validated assessment tools developed some disease specific some age specific 2 examples Mini Nutritional Assessment (MNA) Subjective Global Assessment (SGA) ‘Malnutrition Universal Screening Tool’ (‘MUST’) A simple 5 step validated tool for use by all care workers in all care settings: Step 1-height and weight to obtain BMI Step 2- recent unintentional weight loss Step 3- effect of acute disease Step 4- overall score / category of risk Step 5- management guidelines ‘Malnutrition Universal Screening Tool’ (‘MUST’) Malnutrition Screening Tool (MST) Have you lost weight recently without trying? If NO If unsure If YES, how much weight have you lost? 1 – 5 kg (2 – 11 lb) 6 – 10 kg (1 – 1½ st) 11 – 15 kg (1¾ - 2⅓ st) > 15 kg (> 2⅓ st) Unsure Have you been eating poorly because of a decreased appetite? If NO If YES Total If the score is 2 or more please refer to the dietitian. (Ref: Ferguson M et al, Nutrition 15: 458-464, 1999) 0 2 1 2 3 4 2 0 1 ‘MUST’ e-learning Link to Hospital module: https://secure.digitalroutes.co.uk/bapen The Short Nutritional Assessment Questionnaire (SNAQ) Question Score Did you lose weight unintentionally? >6kg in the past 6 month 3 >3kg in the past month 2 Did you experience a decreased appetite over the past month? 1 Did you use supplemental drinks or tube feeding over the past month? 1 Mini Nutritional Assessment (MNA) Screening and Assessment tool for the identification of malnutrition in the elderly Considers: Dietary Intake – foods, patterns Weight change, BMI, Muscle circumferences Functional impairment, Independence, Living arrangements Psychological issues, Self assessment Subjective Global Assessment Valid assessment tool Strong correlation with other subjective and objective measures of nutrition Highly predictive of nutritional status in a number of different patient groups Quick, simple and reliable Subjective Global Assessment…features Medical History Weight change Dietary intake GI symptoms Functional impairment Physical Examination Loss of subcutaneous fat Muscle wasting Oedema and ascites Subjective Global Assessment …Classifications A B C Well nourished Moderately malnourished or of malnutrition Severely malnourished suspected Adult Ambulatory Screen Full Nutrition Assessment Step 1…Data collection Systematic Approach Assessment based on clinical/psychosocial/physical information Dietary Anthropometric Biochemical Physical Including Subjective (eg. signs/symptoms of nutritional problem, appetite) Objective (eg. Lab results) Data Collection… An Example… A B C D E A B C D E Anthropometry Biochemical Data Clinical signs and symptoms, Dietary Intake Exercise (Energy balance – Consider current level, history and changes medical condition expenditure) Anthropometry Height Weight Weight history / pattern (% weight change) Weight for Height BMI Growth Pattern, head circumference (paediatrics) MAMC TSF Waist circumference Hip circumference WHR Be aware of fluid status, presence of oedema. Anthropometrics Ideal body weight Males: 106 lbs + 6 lbs per inch over 5 ft Females: 100 lbs + 5 lbs per inch over 5 ft Add 10% for large-framed and subtract 10% for smallframed %IBW = (current wt/IBW) X 100 80-90% mild malnutrition 70-79% moderate malnutrition 60-69% severe malnutrition <60% non-survival Anthropometrics %UBW: usual body weight = (current wt/UBW) X 100 85-95% mild malnutrition 75-84% moderate malnutrition 0-74% severe malnutrition % weight change = usual weight – present weight/usual weight X 100 Significant weight loss >5% in 1 month >10% in 6 months Body Mass Index = BMI Evaluation of body weight independent of height BMI = weight (kg)/height2 (m) >40 30-40 25-30 18.5-25 17-18.4 16-16.9 <16 obesity III obesity II overweight normal PEM I PEM II PEM III Bioelectrical Impedance Analysis (BIA) Measures electrical conductivity through water in difference body compartments Uses regression equations to determine fat and LBM Serial measures can track changes in body composition Obesity treatments DEXA: dual-energy X-ray absorptiometry Whole body scan with 2 x-rays of different intensity Computer programs estimate Bone mineral density Lean body mass Fat mass “Best estimate” for body composition of clinically available methods Anthropometrics: additional methods Research methods: precise, but cost prohibitive Total body potassium Underwater weight (hydrodensitometry) Deuterated water dilution Muscle strength and endurance Biochemistry & other Blood Tests (See also disease/condition specific lectures) Objective measures No single test is diagnostic Consider “normal / recommended range” for various and combination of conditions, eg. age, gender, physiological state, disease type and stage Consider clinical significance of test result Test result may reflect immediate intake (eg glucose) or long term status (HbA1c) Other factors to Consider… Other factors can mask/influence test results eg. Acute phase response due to stress / injury ( reduced albumin) GI bleed (higher urea) Blood transfusion (higher serum K and Hb) Surgery (lower Hb and albumin) Nutritional Indicators Ideal indicator or marker is sensitive and specific to nutritional intake Commonly Used “Nutritional Indicators” Albumin Pre-albumin Transferrin Retinol-binding protein Albumin Synthesised in the liver May be useful indicator of nutritional status in “healthy” person. Not a good indicator of protein status during critical illness (due to acute phase response) Long half life (14-20 days) and large body pool slow to respond to improvements in clinical status Factors Affecting Serum Albumin Levels Increased in: Dehydration, blood transfusions, exogenous albumin Decreased in: Overhydration, hepatic failure, inflammation, infection, metabolic stress, post-op, bed rest, pregnancy, nephrotic syndrome. Pre-albumin Also known as Transthyretin, thyroxine binding protein. Synthesised in the liver Relatively short half life (2 days) Negative acute phase reactant - with inflammatory response May be useful in healthy population Transferrin and RBP Transferrin Half life 8-10 days Poor correlation with nutrition status Involved with iron transport, influenced by iron status Retinol Binding Protein (RBP) Half life 12 hours Affected by renal function, Vitamin A and Zn status Unreliable measure of nutritional status C-reactive protein Positive acute phase respondent Increases early in acute stress as much as 1000fold Decreased correlates with end of acute phase and beginning of anabolic phase where nutritional repletion is possible Creatinine Height Index Estimates LBM = actual creat excretion (24 hour urine collection) expected creat excretion Males: IBW X 23 mg/kg Females: IBW X 18 mg/kg >80% normal 60-80% moderately depleted <60% severely depleted Accurate 24-hr urine collection is difficult to obtain in acutecare setting Biochemistry & other Blood Tests, cont’d Interference – drugs, sampling Nutrient-nutrient interactions, drug-nutrient interactions Be aware of hydration status Must interpret lab results with other nutritional parameters Clinical issues to consider: Medical history, treatment and medications Significant factors affecting nutritional intake Fluid balance – input and output, Bowel habits Physical assessment of nutritional status Clinical signs and symptoms Clinical Signs and Symptoms Signs Subjective, impression Descriptive, observation Appearance Visual examination Needs clinical judgement Eg muscle wasting, malnutrition Symptoms Recall, report by subjects Descriptive Eg nausea, itchiness, diarrhoea, anorexia Dietary Intake Is intake meeting requirement? Basic nutrition adequacy Special requirement / disease / conditions Consider factors affecting intake Consider clinical, nutritional and psycho-social issues Methods of collecting information/data ? Relevant and practical Exercise – Energy Balance Nutrition and exercise closely linked – metabolic and physical fitness Functional capacity and Nutritional status Correlation between muscle mass and physical strength, nutritional status and physical function Energy Balance to attain optimal weight and body composition Bed Rest / Inactivity Negative effects on muscles, bone and CV system, eg. 8 g protein loss / day of bed rest Exercise – affects on appetite, bowel function Estimating Nutritional requirements Consider Energy Protein Fluid RDIs for micronutrients Estimating Energy Requirements Indirect Calorimetry preferred method use of a metabolic monitor/cart measures respiratory gas exchanges Differences in oxygen and carbon dioxide content between air going in and air coming out respiratory exchange energy expenditure (Ref: Mann & Truswell(ed) Essentials of Human Nutrition, Chap. 5) Harris Benedict Equation Males (kJ/24hr) BEE = 278 + (57.5 x W) + (20.9 x H) - (28.3 x A) Females (kJ/24hr) BEE = 2741 + (40.0 x W) + (7.7 x H) - (19.6 x A) W = actual weight in kg, H = height in cm, A = age in years. Activity Factors Resting sedated +/- ventilated Resting conscious Bedrest (moving self around bed) Light (mobilizing around ward) 1.3 Moderate (regular, intense physio) 1.0 1.1 1.2 1.4 Injury Factors Medical (IBD, liver/pancreatic d) Surgical (transpl, fistula) Cancer (tumour/leukaemia) Trauma (or minor burns) Sepsis (or other major infection) Major burns 1.11.21.21.21.31.5- 1.2 1.4 1.4 1.4 1.4 1.6 * Refer also to nutrition support and specific clinical lectures Estimating Protein / Nitrogen Requirements From measuring Nitrogen losses from the body (urine, faeces, fistulae/drain losses, burn exudates) Urinary nitrogen excretion can be estimated by measuring urinary urea nitrogen(UUN) excretion from a 24hr urine sample. Estimating Protein / Nitrogen Requirements Using RDA’s Healthy adult 0.75g/kg BW Increased metabolic needs during periods of stress Mild/intermediate stress state eg surgery, fractures 1-1.5g/kg BW Cancer 1.2-1.5g/kg BW Multiple trauma, 1.5+/kg BW extensive burns(>30%) Biochemical Data Used to assess body stores Altered by lack of nutrients, medications, metabolic changes during illness or stress Interpret results carefully Fluid status distorts results “Stressed” states (infection, surgery) effects results Use reference values established by individual lab Hematological Indices Determine nutritional anemias Transferrin: Fe transport protein TIBC: total Fe binding capacity Indicates number of free binding cites on transferrin Fe deficiency: increased transferrin levels, decreased saturation Ferritin: Fe storage protein, increases during inflammation Depressed hemoglobin is an indicator of Fe deficiency anemia Nitrogen balance Goal for repletion is a positive nitrogen balance 24-hr record of protein intake and urine collection is required Done within 48 hr after initiation of nutrition therapy Results not valid in conditions with high protein losses (burns or high-output fistulas) N balance = protein intake/6.25 – (urinary urea N + 3 or 4) Estimation of Nutrient Needs Predictive equation for energy (calorie) needs Harris Benedict uses age, height, and weight to estimate basal energy expenditure (BEE), the minimum amount of energy needed by the body at rest in fasting state In men: BEE (kcal/day) = 66.5 + (13.8 X W) + (5.0 X H) – (6.8 X A) In women: BEE (kcal/day) = 655.1 + (9.6 X W) + (1.8 X H) – (4.7 X A) Where W = weight in kilograms, H = height in centimeters and A = age in years BEE is multiplied by an activity factor and injury factor to predict total daily energy expenditure Activity Categories Confined to bed = 1.0-1.2 Out of bed = 1.3 Very light = 1.3 Light = 1.5 (women), 1.6 (men) Moderate = 1.6 (women), 1.7 (men) Heavy = 1.9 (women), 2.1 (men) Indirect calorimetry/Metabolic Cart Measures CO2 produced and O2 consumed in critically ill patients on ventilators Calculates resting metabolic rate based on gas exchange Respiratory quotient calculated Corresponds to oxidation of nutrients CHO: 1:1 ratio of CO2 produced/O2 consumed Lipid: 0.7:1 ratio Protein: 0.82:1 ratio Mixed diet: 0.85:1 ratio Overfeeding/lipogenesis: >1.0 Injury Categories Surgery Infection Mild = 1.0-1.2 Moderate = 1.2-1.4 Severe = 1.4-1.8 Trauma/Cancer Minor = 1.0-1.1 Major = 1.1-1.2 Skeletal = 1.2-1.35 Blunt = 1.15-1.35 Head trauma treated with steroids = 1.6 Burns Up to 20% body surface area (BSA) = 1.0-1.5 20-40% BSA = 1.5-1.85 Over 40% BSA = 1.85-1.95 Take Home Massage Increase your nutritional knowledge Take care of your proficiency Make good relationship Make a bridge between sciences and practice Be responsible for patients Do not excaudate nutrition Do not undermined nutrition Patients are Central Care of Nutrition The relationship between the patient & the dietetics professional(s) collaborative client-focused individualized Thanks for your attention