Download AP Biology Worksheet /______/_____ Chapter 12 Name Date Bell 1

AP Biology Worksheet
Chapter 12
____________________________/_______/_____
Name
Date Bell
1) The centromere is a region in which
A) chromatids remain attached to one another until anaphase.
B) metaphase chromosomes become aligned at the metaphase plate.
C) chromosomes are grouped during telophase.
D) the nucleus is located prior to mitosis.
E) new spindle microtubules form at either end.
2) How do the daughter cells at the end of mitosis and cytokinesis compare with their
parent cell when it was in G1 of the cell cycle?
A) The daughter cells have half the amount of cytoplasm and half the amount of DNA.
B) The daughter cells have half the number of chromosomes and half the amount of
DNA.
C) The daughter cells have the same number of chromosomes and half the amount of
DNA.
D) The daughter cells have the same number of chromosomes and the same amount of
DNA.
E) The daughter cells have the same number of chromosomes and twice the amount of
DNA.
3) Which term describes two centrosomes arranged at opposite poles of the cell?
A) telophase
B) anaphase
C) prometaphase
D) metaphase
E) prophase
4) Which term describes centromeres uncoupling, sister chromatids separating, and the
two new chromosomes moving to opposite poles of the cell?
A) telophase
B) anaphase
C) prometaphase
D) metaphase
E) prophase
5) If cells in the process of dividing are subjected to colchicine, a drug that interferes with
the functioning of the spindle apparatus, at which stage will mitosis be arrested?
A) anaphase
B) prophase
C) telophase
D) metaphase
E) interphase
6) A cell containing 92 chromatids at metaphase of mitosis would, at its completion,
produce two nuclei each containing how many chromosomes?
A) 12
B) 16
C) 23
D) 46
E) 92
Use the data in Table 12.1 to answer the following questions.
The data were obtained from a study of the length of time spent in each phase of the cell
cycle by cells of three eukaryotic organisms designated beta, delta, and gamma.
7) Of the following, the best conclusion concerning the difference between the S phases
for beta and gamma is that
A) gamma contains more DNA than beta.
B) beta and gamma contain the same amount of DNA.
C) beta contains more RNA than gamma.
D) gamma contains 48 times more DNA and RNA than beta.
E) beta is a plant cell and gamma is an animal cell.
8) The best conclusion concerning delta is that the cells
A) contain no DNA.
B) contain no RNA.
C) contain only one chromosome that is very short.
D) are actually in the G0 phase.
E) divide in the G1 phase.
9) Where do the microtubules of the spindle originate during mitosis in both plant and
animal cells?
A) centromere
B) centrosome
C) centriole
D) chromatid
E) kinetochore
10) Cytokinesis usually, but not always, follows mitosis. If a cell completed mitosis but
not cytokinesis, the result would be a cell with
A) a single large nucleus.
B) high concentrations of actin and myosin.
C) two abnormally small nuclei.
D) two nuclei.
E) two nuclei but with half the amount of DNA.
11) The formation of a cell plate is beginning across the middle of a cell and nuclei are
re-forming at opposite ends of the cell. What kind of cell is this?
A) an animal cell in metaphase
B) an animal cell in telophase
C) an animal cell undergoing cytokinesis
D) a plant cell in metaphase
E) a plant cell undergoing cytokinesis
27) Chromosomes first become visible during which phase of mitosis?
A) prometaphase
B) telophase
C) prophase
D) metaphase
E) anaphase
12) Chromosomes first become visible during which phase of mitosis?
A) prophase
B) telophase
C) prometaphase
D) metaphase
E) anaphase
13) During which phases of mitosis are chromosomes composed of two chromatids?
A) from interphase through anaphase
B) from G1 of interphase through metaphase
C) from metaphase through telophase
D) from anaphase through telophase
E) from G2 of interphase through metaphase
14) Why do chromosomes coil during mitosis?
A) to increase their potential energy
B) to allow the chromosomes to move without becoming entangled and breaking
C) to allow the chromosomes to fit within the nuclear envelope
D) to allow the sister chromatids to remain attached
E) to provide for the structure of the centromere
15) Which of the following best describes how chromosomes move toward the poles of
the spindle during mitosis?
A) The chromosomes are "reeled in" by the contraction of spindle microtubules.
B) Motor proteins of the kinetochores move the chromosomes along the spindle
microtubules.
C) Non-kinetochore spindle fibers serve to push chromosomes in the direction of the
poles.
D) both A and B
E) A, B, and C
16) If mammalian cells receive a go-ahead signal at the G1 checkpoint, they will
A) move directly into telophase.
B) show a drop in MPF concentration.
C) complete the cycle and divide.
D) exit the cycle and switch to a nondividing state.
E) complete cytokinesis and form new cell walls.
17) Which is a general term for enzymes that activate or inactivate other proteins by
phosphorylating them?
A) PDGF
B) MPF
C) Cdk
D) cyclin
E) protein kinase
18) Which of the following is a protein synthesized at specific times during the cell cycle
that associates with a kinase to form a catalytically active complex?
A) PDGF
B) MPF
C) protein kinase
D) cyclin
E) Cdk
19) Which of the following triggers the cell's passage past the G2 checkpoint into
mitosis?
A) MPF
B) PDGF
C) protein kinase
D) cyclin
E) Cdk
20) The "restriction point" occurs here:
A) G0
B) S
C) G1
D) G2
E) M
21) Which of the following is true concerning cancer cells?
A) They do not exhibit density-dependent inhibition when growing in culture.
B) When they stop dividing, they do so at random points in the cell cycle.
C) They are not subject to cell cycle controls.
D) B and C only
E) A, B, and C
1. A
2. D
3. C
4. B
5. D
6. D
7. A
8. D
9. B
10. D
11. E
12. A
13. E
14. B
15. B
16. C
17. E
18. D
19. A
20. C
21. E