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NAME: ONI HERITAGE TOLULOPE MATRIC NO: 14/MHS01/114 COURSE CODE: ANA 203 DEPT: PHYSIOLOGY HISTOLOGY OF MUSCLE AND ITS TYPES Muscle cells, also known as muscle fibers or myocytes, are the fundamental units of your muscles. Humans have three types of muscle: skeletal, smooth and cardiac. Your skeletal muscles are under conscious control, while your smooth muscle -- found in the walls of your blood vessels and your hollow organs -- and cardiac muscle are not. All muscle cells share four primary properties that distinguish them from other cells. Skeletal muscle Skeletal Muscles are those which attach to bones and have the main function of contracting to facilitate movement of our skeletons. They are also sometimes known as striated muscles due to their appearance. The cause of this 'stripy' appearance is the bands of Actin and Myosin which form the Sarcomere, found within the Myofibrils. Skeletal muscles are also sometimes called voluntary muscles, because we have direct control over them through nervous impulses from our brains sending messages to the muscle. Contractions can vary to produce powerful, fast movements or small precision actions. Skeletal muscles also have the ability to stretch or contract and still return to their original shape. Smooth muscle Smooth muscle is also sometimes known as involuntary muscle due to our inability to control its movements, or Unstriated as it does not have the stripy appearance of skeletal muscle. Smooth muscle is found in the walls of hollow organs such as the Stomach, Esophagus, and Bronchi and in the walls of blood vessels. This muscle type is stimulated by involuntary neurogenic impulses and has slow, rhythmical contractions used in controlling internal organs, for example, moving food along the Oesophagus or constricting blood vessels during Vasoconstriction. Cardiac muscle (heart muscle) The three types of muscle (skeletal, cardiac and smooth) have significant differences. However, all three use the movement of actin against myosin to create contraction. In skeletal muscle, contraction is stimulated by electrical impulses transmitted by the nerves, the moto neurons (motor nerves) in particular. Cardiac and smooth muscle contractions are stimulated by internal pacemaker cells which regularly contract, and propagate contractions to other muscle cells they are in contact with. All skeletal muscle and many smooth muscle contractions are facilitated by the neurotransmitter acetylcholine. Function When sarcomere contracts, the Z lines move closer together, and the I band becomes smaller. The A band stays the same width. At full contraction, the thin and thick filaments overlap. The action a muscle generates is determined by the origin and insertion locations. The cross-sectional area of a muscle (rather than volume or length) determines the amount of force it can generate by defining the number of sarcomeres which can operate in parallel.[citation needed] The amount of force applied to the external environment is determined by lever mechanics, specifically the ratio of in-lever to out-lever. For example, moving the insertion point of the biceps more distally on the radius (farther from the joint of rotation) would increase the force generated during flexion (and, as a result, the maximum weight lifted in this movement), but decrease the maximum speed of flexion. Moving the insertion point proximally (closer to the joint of rotation) would result in decreased force but increased velocity. This can be most easily seen by comparing the limb of a mole to a horse - in the former, the insertion point is positioned to maximize force (for digging), while in the latter, the insertion point is positioned to maximize speed (for running). This type of muscle is found solely in the walls of the heart. It has similarities with skeletal muscles in that it is striated and with smooth muscles in that its contractions are not under conscious control. However this type of muscle is highly specialized. It is under the control of the autonomic nervous system, however, even without a nervous impute contractions can occur due to cells called pacemaker cells. Cardiac muscle is highly resistant to fatigue due to the presence of a large number of mitochondria, myoglobin and a good blood supply allowing continuous aerobic metabolism Anatomy Function of Muscle Tissue The main function of the muscular system is movement. Muscles are the only tissue in the body that has the ability to contract and therefore move the other parts of the body. Related to the function of movement is the muscular system’s second function: the maintenance of posture and body position. Muscles often contract to hold the body still or in a particular position rather than to cause movement. The muscles responsible for the body’s posture have the greatest endurance of all muscles in the body—they hold up the body throughout the day without becoming tired. Another function related to movement is the movement of substances inside the body. The cardiac and visceral muscles are primarily responsible for transporting substances like blood or food from one part of the body to another. The final function of muscle tissue is the generation of body heat. As a result of the high metabolic rate of contracting muscle, our muscular system produces a great deal of waste heat. Many small muscle contractions within the body produce our natural body heat. When we exert ourselves more than normal, the extra muscle contractions lead to a rise in body temperature and eventually to sweating. The Four Properties of Muscle Cells Muscle cells, also known as muscle fibers or myocytes, are the fundamental units of your muscles. Humans have three types of muscle: skeletal, smooth and cardiac. Your skeletal muscles are under conscious control, while your smooth muscle -- found in the walls of your blood vessels and your hollow organs -- and cardiac muscle are not. All muscle cells share four primary properties that distinguish them from other cells. Excitability For a muscle to contract and do work, its cells must be stimulated, most often by the nerves supplying them. Nervous impulses cause the release of the neurotransmitter acetylcholine at the nerve-muscle junction, and the acetylcholine activates receptors on the surface of the muscle cell. This results in an influx of positively charged sodium ions into the muscle cell and a depolarization of the muscle cell membrane, which in the resting state is quite negatively charged. If the membrane becomes sufficiently depolarized, an action potential results; the muscle cell is then "excited" from an electrochemical standpoint. Contractility In the case of skeletal muscles, muscle cells contract when stimulated by neural input; smooth and cardiac muscles do not require this input. When a muscle cell is excited, the impulse travels along various membranes of the cell to its interior, where it leads to the opening of calcium channels. Calcium ions flow toward and bind to a protein molecule called troponin, leading to sequential changes in shape and position of the associated proteins tropomyosin, myosin and actin. The upshot is that myosin binds to small strands within the cell called myofilaments and pulls them along, causing the cell to shorten, or contract. Since this is going on simultaneously and in a coordinated fashion in many thousands of myocytes at the same time, the muscle as a whole contracts. Extensibility Most of your body's cells lack the capacity to stretch; attempting to do so only damages or destroys them. Your long, cylindrical muscle cells, however, are a different story. Muscle cells contract, and in order for them to retain this ability, they must accordingly possess extensibility, or the capacity to lengthen. Your muscle cells can be stretched to about three times their contracted length without rupturing. This is important because in a lot of coordinated movements, so-called antagonistic muscles operate such that one is lengthening while the other is contracting. For example, when you run, the hamstring in the back of your thigh contracts while your quadriceps are extended and conversely. Elasticity When something is described as elastic, this is simply a statement that it can be stretched or contracted by some amount above or below its resting or default length without damaging it, and that it will return to this resting length once the stimulus for stretching or contraction is removed. Your muscles require the property of elastic recoil for them to be able to do their jobs. If, say, your biceps muscles failed to recoil to their resting length after being stretched during a series of curling exercises, they would become slack, and slack muscles with no tension are unable to generate any force and are therefore useless as levers. Reference: www.readingfanatic.com