Download Amino Acids 40 Profile

Amino Acids 40 Profile - Plasma
Assessing the Body's Fundamental Building Block
The Amino Acids 40 Plasma Profile
In addition to pinpointing problems in amino acid absorption and determining essential amino
acid imbalances, the plasma amino acid 40 test includes evaluation of limiting, branched chain,
and essential and non-essential amino acids. It also identifies several functional categories, such
as neuroendocrine, vascular, collagen status and detoxification, along with five calculated ratios,
and identifies vitamin and mineral insufficiencies.
Plasma Amino Acids
Fasting plasma levels represent a homeostatic balance between supply and utilization of amino
acids making this specimen option ideal for repeated assessments to monitor progress of
treatment. Collecting a fasting plasma specimen from a patient removes recent dietary intake
effects. The following factors can effect changes over time in plasma:
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Chronic dietary intake
Digestive efficiency
Hepatic uptake
Skeletal muscle's ability to maintain transamination
Why is amino acid testing important?
Amino acids, known as the "building blocks" of proteins, are found in every tissue of the body.
They play a major role in nearly every chemical process that affects both physical and mental
function including the formation of ligaments, tendons, bones, and antibodies, as well as
regulation of enzymes and blood transport proteins. Twenty different amino acids are used to
synthesize proteins.
The human body can synthesize all of the amino acids necessary to build proteins except for ten
called the "essential amino acids". These ten must be included in the diet or supplemented to be
in adequate supplies. Failure to obtain enough of even 1 of the 10 essential amino acids has
serious health implications and can result in degradation of the body's proteins. Muscle and other
protein structures may be dismantled to obtain the one amino acid that is needed.
Amino acids have more diverse functions than any other nutrient group,
including:
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Gastrointestinal function
Cellular energy production
Detoxification
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Neurotransmitter metabolism
Muscle catabolism
Collagen
Nutritional markers
Vascular function
Conditions Associated with Amino Acid Changes in Plasma:
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Cardiovascular disease
Depression
Anxiety
Insomnia
Chronic Fatigue Syndrome
Multiple sclerosis
Rheumatoid arthritis
Epilepsy
Congestive heart failure
Impotence/Erectile pain syndromes
Multiple chemical sensitivities
Detoxification disorders
Autism Spectrum Disorders
Alzhiemer's Disease
Hypothyroidism
Arrhythmias
Hypertension
ADD/ADHD
Infertility
Customized Amino Acid Formula
A formula for a customized amino acid blend, based on your patient's specific test results, is
provided with every plasma amino acid test result. These customized amino acid formulations
provide appropriate amounts of essential and conditionally essential amino acids, delivered in a
balanced ratio to offset the risk of imbalance sometimes seen with the use of single amino acid
supplements. This blend can be made by many compounding pharmacies.
Additional Amino Acids Profiles to Consider:
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Amino Acids Plasma 20 Profile
Bloodspot Amino Acids 11 Profile
Bloodspot Amino Acids 20 Profile
Test name(s)
0010 - Amino Acids - 40 analytes
0310 - Amino Acids - 40 analytes NY
Description
Fasting plasma levels of amino acids represent homeostatic balance between supply and
utilization of these critical building blocks. Problems in amino acid metabolism are revealed by
the amino acids and metabolites that are reported in categories according to function. Amino acid
analysis helps with determination of amino acid imbalances, evaluation of functional vitamin and
mineral deficiencies, and diagnosis of metabolic disorders. A formula for a custom amino acid
blend is provided with every plasma amino acid test result. This blend can be made by any
compounding pharmacy.
Method
Reversed Phase UHPLC Method
Turnaround Time
7-14 days, 10 days average
Analytes
1-Methylhistidine
3-Methylhistidine
Alanine
Alpha-Aminoadipic Acid
Alpha-Amino-N-Butyric Acid
Anserine
Arginine
Asparagine
Aspartic Acid
Beta-Alanine
Beta-Aminoisobutyric Acid
Carnosine
Citrulline
Cystahionine
Cystine
Ethanolamine
Gamma-Aminobutyric Acid
Glutamic Acid
Glutamine
Glycine
Histidine
Homocystine
Hydroxylysine
Isoleucine
Leucine
Lysine
Methionine
Ornithine
Phenylalanine
Phosphoethanolamine
Phosphoserine
Proline
Sarcosine
Serine
Taurine
Threonine
Tryptophan
Tyrosine
Valine
Ratios
Phenylalanine/Tyrosine
Glutamic Acid/Glutamine
Hydroxyproline/Proline
Alpha-ANB/Leucine
Tryptophan/LNAA (Large Neutral Amino Acids)