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STUDY OUTLINE FOR TRANSPORT THROUGH A MEMBRANE I. II. III. IV. Membrane Structure a. Phospholipid bilayer b. Proteins embedded c. Fluid Mosaic Model Membrane Function a. Regulates what enters and leaves b. Maintains homeostasis c. Partitions eukaryotic cell into compartments d. Acts as a boundary e. Selectively permeable Different fatty acids Different proteins Different functions f. Protein functions (enzymes, transport, receptors, recognition) g. Cholesterol function h. What is responsible for different selective permeability in different membranes? What can and can’t pass through membrane a. Polar and ionic can’t (NaCl, glucose, amino acids, water) b. Nonpolar can (O2, steroids, and CO2) c. Small can d. Large can’t (amino acids) Passive transport a. No energy required but requires a concentration gradient b. Moves with or down concentration gradient (area of high concentration to area of low concentration) c. Due to random motion of molecules (kinetic energy, Brownian motion) d. Substances move independently of each other e. Dynamic equilibrium f. Three types of passive transport Diffusion i. O2 and CO2 move completely by diffusion ii. No energy required iii. Requires concentration gradient iv. Understand how oxygen and carbon dioxide move through lungs, circulatory system, and body cells Osmosis i. Diffusion of water through a selectively permeable membrane. ii. Hypertonic-Higher concentration of solute iii. Hypotonic-Lower concentration of solute iv. Isotonic-Equal concentration of solute v. vi. vii. V. VI. Facilitated diffusion i. ii. iii. iv. v. All three above compare two solutions-one inside cell and one outside cell. Tries to reach equal solute concentration. Water moves from hypotonic region to hypertonic region based on total solute concentration. No energy required Requires concentration gradient Has help from membrane proteins High to low concentration Through a membrane Water Balance between cells is crucial a. Animal Cells Lysis in hypotonic solution Shrivel in hypertonic solution Normal in isotonic solution (best environment) b. Plant Cells-Rigid cell makes a difference Flacid in isotonic solution Plasmolysis in hypertonic solution Turgid in hypotonic solution (best environment) Active Transport a. Requires energy b. Often goes against concentration gradient c. Through a membrane d. Requires protein e. Types of active transport Exocytosis Endocytosis i. Phagocytosis ii. Pinocytosis iii. Receptor mediated