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CHAPTER 13 SECTION 1 (PAGE 366) I Blood Job A. Carry oxygen (O) from lungs to all body cells— carries carbon dioxide (CO) out of the cells. B. Blood carries waste products from cells to kidneys to be removed. C. Blood transports nutrients to body cells. D. Cells and molecules fight infections in blood, heal wounds. II Blood Parts A. plasma—liquid part of the blood made of water. 1. makes up more than half of blood made of water. 2. nutrients, minerals and oxygen are dissolved here—wastes also carried here. B. Red blood cells- have no nuclei 1. carry hemoglobin – molecule that carries O and CO. 2. hemoglobin carries O to cells and CO from cells as waste. 3. live only 120 days-2million-3million made every second. C. White blood cells 1. less in number than RBC-1mm has 5-10 thousand. 2. fight bacteria, viruses, and other infections. 3. go into tissues from blood and kills bacteria and than absorb it. 4. live only 1-3 days. D. Platelets 1. irregularly shaped cells fragments help clot blood. 2. 400,000 for every 1mm 3. live only 5-9 days. III Blood clotting 1. platelets stick to outside edge 2. platelets release fibrin-threadlike fibers where RBC are caught like a net. 3. catches blood cells and plasma—scab is formed 4. skin repairs itself underneath. 5. hemophilia-lacks clotting platelets-get blood transfusions of platelets IV Blood types A. 4 types a. A b. B c. AB d. O B. A, B, AB have antigens for those types on their blood cells C. O has no antigens D. AB is the universal recipient E. O is the universal donor Table –Who can donate and receive blood A B AB O A B AB O F. Receive wrong type—blood clots in blood vessels G. RH factor (+ or -) a. RH in blood-(+) b. RH not in blood-(-) (+) and (-) cannot get transfusions-pregnancy- RHneeds a Rhogam shot to prevent problems. V Blood disease A. anemia- not enough hemoglobin can’t get enough O to body parts. Causes--1. loss of blood 2. poor diet 3. hereditary B. sickle-cell anemia—sickle shaped Red Blood Cells. C. Lukemia—too many white blood cells in the body—immature cells and kill mature cells. SECTION 2 (PAGE 371) I Cardiovascular System A. heart, vessels, blood B. heart- 4 chambers Two upper chambers—atria or atrium Two lower chambers—ventricles C valves separate chambers II 3 types of circulation A. coronary—circulation through the vessels of the heart. i. Blocked—heart attack results B. pulmonary—circulation of the heart to the lungs – low O i. blood to heart—high O Diffusion—allows O into blood hemoglobin—wastes move out into lungs. **PATHWAY** Begins—right atrium -> right ventricle-> pulmonary artery-> pulmonary capillaries-> pulmonary veins-> left atrium-> left ventricle-> aorta-> the body-> inferior vena cava and superior vena cava-> right atrium. C. Systemic Circulation-moves blood to all organs and body tissues. i. O rich blood moves out of the heart to body ii. Body diffuses O into tissues and pick up waste iii. Blood returns to heart to be pumped to lungs for more O. IV Blood vessels A. capillaries- smallest vessels (diffusion takes place here) between veins and arteries. B. Arteries- carry blood away from heart. i. Muscular and pump blood pulse. C. veins—carry blood back to the heart- valves keep blood from flowing backwards. V Blood pressure A. pressure of blood against the walls of arteries. B. highest in the arteries, lowest in veins C. pressure rises when heart beats-lowers when it relaxes D. nerves in arteries send messages to the brain— the brain slows or speeds up the heart. VI Cardiovascular disease A. atherosclerosis- fatty deposits build up on arterial walls a. coronary arteries is very serious B. hypertension- blood pressure higher than normal all the time a. wears heart out—must work harder to pump blood. C. prevention a. exercise b. eating well c. no smoking VII Lymphatic system A. vessels and nodes that help filter blood and fight disease. B. Lymph- tissue fluid diffuses into the lymphatic capillaries C. Produces lymphocytes- helps body defend against disease-causing organisms D. Lymph nodes swell when collecting disease SECTION 3 (PAGE 377) I Immunity A. first defense-skin, respitory, digestive, and circulatory systems. 1. skin- keeps pathogens from entering body, oil and sweat helps. 2. respitory system- traps pathogens with hairlike structures called cilia and mucus. Mucus weakens cell walls of pathogens. 3. digestive system-uses siliva, enzymes, HCL and mucus. 4. white blood cells- surround and eat pathogens 5. inflammation- attracts white blood cells to swollen, warm area. B. specific defense 1. fights antigens-complex molecules 2. Killer T-cells – release enzymes that destroy invading matter. 3. helper T-cells – they turn on immune system to make antibodies. 4. memory T-cells – help make antibodies to specific pathogens. II Types of Immunity A. active immunity—your body makes its own antibodies- vaccinations. B. Passive immunity—antibodies produced in another animal and given to your body—newborns get antibodies from mother. i. These do not stay long. SECTION 4 (PAGE 381) I Disease A. micro-organisms cause disease—Louis Pasteur B. Pasteurization—process of heating a liquid to a certain temperature that will kill bacteria in it. EX: milk Page 381 table 3 Page 383 fig. 13—Koch’s rules C. infectious disease—caused by a virus, bacteria, protist, or fungus and spread by a infected organism. a. Spreads by 1. food 2. water 3. air 4. objects 5. biological vectors—carriers b. human vectors-people that carry disease i. Lister-proposed the first steril ER using carbolic acid soap ii. STD-spread through humans by sexual contact a. Examples-gonorrhea, syphilis, Chlamydia, herpies II HIV A. Human Immunodeficiency Virus B. Exists in the blood and body fluids C. Can hide for years D. Blood to blood contact—infection occurs E. Pregnant women can give it to their babies F. Can not live outside the body III AIDS A. Acquired Immune Deficiency Syndrome (AIDS) B. Attacks the immune system C. Can not fight it with antibiotics D. Anti-virals are used—terrible side effects E. How it kills— a. Attacks helper T-cells b. Enters T-cell and multiplies c. Bursts open-releases more HIV d. More T-cells destroyed than not e. Immune system is destroyed f. 2 million cases world wide-- 816,000 in U.S. IV Fight Disease A. soap and water B. bandages C. hygiene D. exercise V Non-infectious Disease A. not spread person to person B. chronic-lasts a long time Ex: lyme disease D. allergies a. Allergens are substances cause an allergic reaction b. Body reacts by making histamines—causing redness, swelling of tissues and glands c. Anti-histamines are given to stop reaction to allergen d. Treatment—drugs, injections E. diabetes a. level of insulin produced by pancreas are not normal b. Type 1-too little or no insulin c. Type 2- too much insulin d. Tired, thirst, frequent urination, tingling are signs. e. Long term high glucose—blurred vision, kidney failure, heart attack, stroke, loss of feeling, diabetic coma. F. Cancer a. Caused by uncontrolled cell growth b. Table 4 page 387 c. Exposure to chemicals, smoking, carcinogens are causes d. Table 5 page 388—warning signs e. Prevention—know the signs, healthy lifestyle