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Cell Growth and Division Chapter 5 Mr. Scott Limits to cell growth 10-1 Cell Growth The ________________ a cell is, the more demands the cell places on its _______________________________. The cell has trouble moving enough ______________________________ across the cell membrane 10-1 Cell Growth DNA “overload” DNA – Small cells have ____________ need for that information than big cells Big cells may need so much information that the single copy of DNA cannot provide it to all areas of the cell 10-1 Cell Growth Exchanging materials Surface area of a cell determines the amount of material exchanged Total area of the cell membrane Volume of a cell determines how fast these materials are produced (waste) or used (food and oxygen) 10-1 Cell Growth Ratio of surface area to volume Surface area / volume Surface area units 2 Volume units 3 10-1 Cell Growth If the length of the cell doubles what happens to the ______? Volume Surface Area Ratio SA / V W hat does this do to the cell? Division of the cell 10-1 Cell Growth Cell division The process by which a cell _____________________________ This occurs when the cell becomes too big Before a cell divides, it __________________________________ 10-2 Cell Division Chromosomes Carries the cells ____________________ from one generation to the next. Made of _______________________________________________ Each cell contains a specific number of chromosomes Humans – 46 Ap e s - 4 8 Flies - 8 Carrot – 18 Dog - 78 10-2 Cell Division Chromatids One of two __________________ “sister” parts of a duplicated chromosome Area where the chromatids of a chromosome are attached 10-2 Cell Division The cell cycle Interphase Period of the cell cycle between ___________________________ Cell cycle During the cell cycle, a cell ______________________________________________________ each of which then begins the cycle again 10-2 Cell Division Events of the cell cycle G1 phase S phase DNA replication G2 phase M phase ) Mitosis 10-2 Cell Division Division of the cell nucleus Four phases (PMAT) 10-2 Cell Division Prophase 1st phase Chromosomes become visible Centrioles separate Spindles begin to form 10-2 Cell Division Metaphase Chromosomes ____________________________________ Each chromosome is connected to a spindle fiber 10-2 Cell Division Anaphase Sister chromatids __________________________________ Chromosomes move toward opposite poles 10-2 Cell Division Telophase Chromosomes gather at the poles and lose their shape ______________________________ surround each set of chromosomes Cytokinesis 10-2 Cell Division Division of the _______________________________________ Each daughter cell has an identical set of chromosomes 10-3 Regulating the Cell Cycle Controls of cell division Cell growth can be turned on or off On Off Cell cycle regulators 10-3 Regulating the Cell Cycle Something that tells the cell when it is time to divide, duplicate their chromosomes, or enter another phase Protein that cause spindles to form Regulate the timing of the cell cycle in eukaryotic cells Regulating the Cell Cycle Internal regulators __________________________ that respond to events inside the cell Allow the cell to proceed only when certain processes have happened Regulating the Cell Cycle External regulators Proteins that respond to events ____________________ the cell Direct the cell to speed up or slow down the cell cycle Ex. _____________________________ Uncontrolled cell growth Regulating the Cell Cycle Cancer cells do not respond to the signals that regulate the growth of most cells Asexual Reproduction _______________________________ is similar in function to mitosis. Asexual reproduction is the creation of offspring from a single parent. Binary fission produces two daughter cells genetically identical to the parent cell. Binary fission occurs in ______________________. Asexual Reproduction Environment determines what form of reproduction is most advantageous. Asexual reproduction is an advantage in ______________________________. Sexual reproduction is an advantage in ____________________________. Asexual Reproduction Some eukaryotes reproduce through mitosis. _____________________ forms a new organism from a small projection growing on the surface of the parent. Asexual Reproduction ___________________ is the splitting of the parent into pieces that each grow into a new organism. • Vegetative reproduction forms a _______________________________________________ on the parent plant. Multicellular Life Multicellular organisms depend on interactions among different cell types. ____________________ are groups of cells that perform a similar function. Organs are groups of ____________________ that perform a specific or related function. Organ systems are groups of organs that carry out similar functions. Multicellular Life Specialized cells perform specific functions. Cells develop into their mature forms through the process of ___________________________________ Cells differ because different combinations of genes are expressed. A cell’s location in an __________________________ helps determine how it will differentiate. Multicellular Life Stem cells are unique body cells. Stem cells have the ability to: __________________________________ themselves remain _______________________________________ in form develop into a variety of specialized cell types Multicellular Life Stem cells are classified into three types. ______________________________, or growing into any other cell type ______________________________, or growing into any cell type but a totipotent cell ______________________________, or growing into cells of a closely related cell family Multicellular Life Stem cells come from adults and embryos. Adult stem cells can be hard to isolate and grow. The use of adult stem cells may prevent transplant rejection. The use of embryonic stem cells raises ethical issues Embryonic stem cells are ______________________and can be grown indefinitely in culture. Multicellular Life The use of stem cells offers many currently realized and potential benefits. Stem cells are used to treat ______________________________________. Stem cells may cure disease or replace damaged ___________________. Stem cells may revolutionize the drug development process.