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Biology End-of-Course Test Study Guide This study guide is based on the NC Standard Course of Study for Biology. Goal 1: Learner will develop abilities necessary to do and understand scientific inquiry. Hypothesis Independent Variable vs. Dependent Variable Control Group vs. Experimental Group Measurement Tools Interpreting/Analyzing Data Interpreting/Analyzing Charts, Graphs Observations vs. Inferences vs. Predictions Lab Safety Hazards Quantitative Data vs. Qualitative Data Goal 2: Learner will develop an understanding of the physical, chemical and cellular basis of life. Organic compound groups (know monomers, examples and functions of proteins, lipids, carbohydrate, nucleic acids) Know Structure/Function of Starch, Cellulose, Insulin, Glycogen, Glucose, Hemoglobin, Fats, DNA and RNA Iodine used for starch test Brown Paper used for lipid test Benedict’s Solution used for monosaccharide test Biuret Reagent used for protein test Enzymes (lock and key, characteristics, factors that effect enzyme function, etc.) Cellular Organelles structure and function (nucleus, plasma membrane, cell wall, mitochondria, vacuoles, chloroplasts and ribosomes) Microscope technique (total magnification) Cellular organization (cellstissuesorgansorgan systems) Plant cells vs. Animal cells Homeostasis (temperature, pH, water balance, etc.) Osmosis Diffusion Passive vs. Active Transport Selective Permeability of cell membrane Cell Reactions to different solution concentrations Acids vs. Bases Buffers Energy for biochemical reactions Equation (reactants and products) for Photosynthesis Equation (reactants and products) for Cellular Respiration Aerobic vs. anaerobic respiration Lactic acid fermentation Alcoholic fermentation Goal 3: Learner will develop an understanding of the continuity of life and the changes of organisms over time. Compare and contrast DNA and RNA Base pairing rules DNA Replication Process Mutations Hydrogen bonding in DNA Protein Synthesis (transcription and translation) Peptide Bonding Codon Chart Expression of genes in different cells Cancer Tumors Sexual vs. Asexual Reproduction Compare and contrast Mitosis and Meiosis Haploid vs. Diploid Cells Mitosis Phases/Diagrams in order (Be able to sequence the pictures.) Sources of variation (crossing over, random assortment of chromosomes, gene mutations, nondisjunction, fertilization) Dominant vs. Recessive Genotype vs. Phenotype Mendel’s experiments and laws Karyotyping (gender determination and chromosome abnormalities) Homozygous vs. Heterozygous Complete vs. Incomplete dominance Codominance Autosomal inheritance patterns (sickle cell, cystic fibrosis and Huntington’s disease) Multiple alleles (blood types) Polygenic traits (hair color, skin color, height) Sex-linked traits (colorblindness and hemophilia) Understand why males are more likely to express sex-linked traits Human sex chromosomes (male and female) Independent assortment Test cross Pedigrees Punnett squares (monohybrids and dihybrids) Human Genome project Applications of biotechnology (DNA fingerprinting, gel electrophoresis, transgenic organisms) Ethical issues associated with biotechnology Theory of evolution by Natural Selection Composition of early Earth’s atmosphere (Oparin, Miller and Urey) Endosymbiotic Theory Homologous vs. Analogous structures Biochemical similarities of different species How is common ancestry determined among species? Fossil dating Geographic isolation vs. Reproductive isolation Speciation Applications of pesticide and antibiotic resistance to natural selection Goal 4: Learner will develop an understanding of the unity and diversity of life. Kingdoms Co-evolution 7 classification categories Binomial nomenclature Basis of classification (evolutionary phylogeny, DNA and biochemical analysis, embryology and morphology) Interpret Phylogenetic trees Similarities and differences between prokaryotic and eukaryotic organisms Similarities and differences among eukaryotic kingdoms (Animalia, Plantae, Fungi and Protista) Dichotomous Keys Compare and contrast nonvascular plants, gymnosperms and angiosperms Physiological functions among annelids, insects, amphibians and mammals Animal transport, excretion, respiration, regulation, nutrition, synthesis, reproduction, growth and development Structural adaptations for organisms to live on land Viruses (HIV, Influenza, Smallpox) Contrast viruses and bacteria Bacteria (Streptococcus) External effects on health and disease (Malaria, Cancer, Tobacco use, Diet/Exercise, Diabetes, PKU/Diet) Immune response (vaccines, active and passive immunity, T cells, B cells, antibodies/antigens) Nutrition (obesity, poor nutrition, malnutrition and optimal health) Animal behavior Innate behavior (migration, estivation, hibernation, instinct, taxis) Learned behavior (habituation, imprinting, trial and error, conditioning) Social behavior (pheromones, courtship dances, territoriality) Goal 5: Learner will develop an understanding of the ecological relationships among organisms. Levels of ecological organization (organismpopulationcommunityecosystembiosphere) Symbiotic relationships (commensalisms, mutualism, parasitism) Predator/prey relationships Biotic and abiotic factors Effect of limiting factors on carrying capacity Interpret population growth graphs Relationship of Carbon Cycle to photosynthesis and cellular respiration Trophic levels and energy transfer (food chains, food webs and energy pyramid) The sequence of organisms in food chains Human population growth (birth rate, death rate, density, population size, resources) Human impact on ecosystems (acid rain, habitat destruction, introduction of non-native species) Greenhouse effect (Carbon cycling, impact of human influence, volcanoes) Deforestation Pesticide use Bioaccumulation research Examples of sustainable practices/stewardship Biology students should use their class notes, textbooks, worksheets, handouts, labs and all other materials from this school year to prepare for the Biology End-of-Course Test.