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BI 102 2013 Objectives and Assessments Week Activity # Any Any Lecture 1 Nature of Science (Lecture) 10 11 Compare and contrast aspects of the lives of Gregor Mendel and Charles Darwin. Exam #1 12 Describe the scientific studies and contributions of both Mendel and Darwin. Exam #1 2 3 4 5 7 8 9 1 Darwin, Mendel, and Scientific Inquiry (Recitation) 13 14 Genetics and Evolution of Corn (Lab) 15 16 17 18 Readings (Science, Darwin) 19 20 Mendel (Lecture) 21 2 22 DNA and Proteins (Lecture) Primary Assessment Describe a current biology news story that was introduced in lecture. Describe how science differs from other fields of study. List and describe the steps of the research process. Distinguish between theories and laws. Provide examples of how technology and society impact science. Describe early ideas of inheritance and whether species changed over time. Discuss the types of data Darwin collected on his voyage and in the years following the voyage. List the basic assumptions of Darwin’s theory of natural selection. Provide the response to Darwin’s theory and its role in the organization of biological knowledge. Define and provide different aspects of science, including observations, inferences, hypotheses, theories, and laws. 6 Darwin (Lecture) Objective 23 Reflect on personal understandings of science. Describe and complete a monohybrid (“one trait”) cross of corn kernel color, including three generations (P, F1, and F2). Define the following genetics terms: dominant, recessive, genotype, phenotype, gene/allele, homozygous, and heterozygous. Provide characteristics of corn structures, traits and life cycle. Discuss corn history including human domestication and uses of corn. Describe four assumptions of the scientific world view, five aspects of scientific inquiry, and four characteristics of the scientific enterprise. Discuss Darwin’s early life, how the Galápagos finches are an example of natural selection, and how Darwin’s theory related to the works of Lyell, Malthus, Wallace, and Boucher de Perthes. Describe Mendel’s work, including his background, the organisms used, and the conclusions Mendel drew from his experiments. Discuss how Mendel’s work was initially received and how the work of Meischer and others led to the realization of the significance of Mendel’s work. Recall the research studies that led to our understanding that DNA (not proteins) is the substance of heredity. Describe the structure of DNA, including the names and roles of the researchers associated with the discovery of DNA structure. 181 Any Exam Exam #1 Exam #1 Exam #1 Exam #1 Exam #1 Exam #1 Exam #1 Exam #1 Exam #1 Portfolio #1 Exam #1 Exam #1 Exam #1 Portfolio #1 Exam #1 Exam #1 Exam #1 Exam #1 Exam #1 Exam #1 24 25 26 27 Artificial Selection (Recitation) 28 29 30 31 Chromosomes, DNA, and Proteins (Lab) 32 33 34 Readings (Mendel, DNA and RNA, Protein Synthesis) 35 36 37 38 Mutation and Variation (Lecture) 39 40 41 42 Development (Lecture) 3 43 44 45 Variation (Recitation) 46 47 48 Reproduction and Growth (Lab) 49 50 51 Explain the relationship between chromosomes, DNA, genes, alleles, proteins, and observable traits. Provide information on basic protein structure and function including amino acids and polypeptides. Outline the steps of protein synthesis and provide examples of how toxins and antibiotics relate to protein synthesis. Describe possible processes of how wolves may have developed into many varieties of modern dogs. Give examples of traits artificially selected for that appear in modern dogs. Provide examples of how inbreeding relates to genetic disorders in dogs. Observe corn seedlings and analyze information. Utilize a model to construct DNA, make an mRNA copy of DNA (process of transcription) and from the mRNA, produce a small protein fragment (process of translation). Describe details of chromosome, DNA, RNA, and protein structure and function. Define terms related to genomes, including gene, intron, exon, and the genetic code. Summarize the process of protein synthesis in a drawing. Explain Mendel’s principles of segregation and independent assortment. Contrast the structures and functions of DNA and RNA. Distinguish between the three types of RNA, describe the processes of transcription and translation, and provide examples of gene control. List examples of non-Mendelian inheritance, including codominance, incomplete dominance, polygenic traits, and sex-linked traits. Discuss the complexity of inheritance, including variable expression of genes, modifier genes, master control genes, and environmental effects. Describe types of mutations, causes of mutations, and effects of mutations. Link chromosomes to the processes of meiosis, fertilization, mitosis, growth and overgrowth (cancer). Outline the role of genes in embryonic development, including organ development Explain how gene expression can be controlled, resulting in different cells making different proteins even though they have the same chromosomes. Explain what “nature versus nurture” means, including the possible impact of epigenetics. Provide different sources and examples of variation within species. Utilize different models linking variation to artificial and natural selection. Follow the inheritance pattern of traits in a dihybrid cross. Complete a dihybrid cross with correct genotypes and phenotypes. Describe the processes of mitosis and meiosis. Link meiosis and mitosis to the life cycles of various species. Utilize a model to demonstrate how crossing over during meiosis can lead to increased genetic variation. 182 Exam #1 Exam #1 Exam #1 Exam #1 Exam #1 Exam #1 Portfolio #1 Exam #1 Exam #1 Exam #1 Portfolio #1 Exam #1 Exam #1 Exam #1 Exam #1 Exam #1 Exam #1 Exam #1 Exam #1 Exam #1 Exam #1 Exam #1 Exam #1 Exam #1 Portfolio #2 Exam #1 Exam #1 Exam #1 52 53 Readings (Mutations, Epigenes, Fruit Flies) 54 55 56 Mechanisms of Change (Lecture) 57 58 59 60 Eons of Life on Earth (Lecture) 61 62 63 4 Evolutionary Case Studies (Recitation) 64 65 66 67 Eras and Periods of Time (Lab) 68 69 70 Readings (Darwin’s Finches, Evolution Today 71 72 73 Tree of Life (Lecture 74 75 5 Origins of Species (Lecture) Dinosaurs and 76 77 78 79 Map the location of genes on a chromosome using crossover data. Distinguish between types of single base (“point”) mutations, insertions, deletions, translocations, and duplications. Describe the epigenetics, including what the “epigenome” is and examples of research studies that may suggest the significance of epigenetic changes. Describe the fruit fly as a model research organism, including the name of the species commonly use, its behaviors, genome size, and life cycle. Explain how mutations can increase variation and why genetic variation is necessary for evolutionary change. Define genetic drift and gene flow and provide examples of each. Define fitness and relate fitness to variation. Provide examples of selection in various species. Discuss the Precambrian, including earth’s characteristics and hypotheses of the origin of life. Outline major transitions of the Paleozoic, Mesozoic, and Cenozoic eras. Provide representative organisms of the Paleozoic, Mesozoic, and Cenozoic eras. Describe how fossils, DNA, and geographical data are used to reconstruct relationships. Provide examples of the impact of variation on evolutionary change. List key aspects of fish evolution. Analyze exam results to improve learning and performance on future exams. Outline geologic time, including major events like the Permian-Triassic extinction. Provide examples of different organisms from the Precambrian and the three most recent eras. Describe fossil organisms, including specimens found in Oregon. Construct a paper timeline that shows the relative timespan of life on Earth. Decribe the Grants’ research on the finches of the Galápagos islands, as well as the conclusions drawn. (you do not need to do the exercises at the bottom). Provide examples of vestigial organs, homologies, characteristics of tetrapods, embryology, and the relationship of DNA to evolution (you are just responsible for the material in the “How do we know living things are related?” section) Define types of evolutionary trees, including phylogenies and cladograms. Describe the types of data used to construct evolutionary trees. Provide an example of how trees are used to develop and test hypotheses about evolutionary transitions Define and provide examples of species. Explain how species can form, including various forms of reproductive isolation. Provide examples of new species forming (speciation). Provide examples of transitions in vertebrate evolution. 183 Portfolio #2 Exam #1 Exam #1 Exam #1 Exam #2 Exam #2 Exam #2 Exam #2 Exam #2 Exam #2 Exam #2 Exam #2 Exam #2 Exam #2 Portfolio #2 Exam #2 Exam #2 Exam #2 Portfolio #2 Exam #2 Exam #2 Exam #2 Exam #2 Exam #2 Exam #2 Exam #2 Exam #2 Exam #2 Other Reptiles (Recitation) 80 81 82 83 Dinosaurs and Speciation (Lab) 84 85 86 Readings (Speciation, Alamosaurus News) 87 88 89 Extinctions (Lecture) 90 91 92 93 Coevolution (Lecture) 94 95 96 6 Mammalian Evolution (Recitation) 97 98 99 100 Islands and Introduced Species (Lab) 101 102 103 Readings Reciprocal Altruism, Vertebrate Evolution) 7 Sexual Selection 104 105 106 Discuss the types of evidence used to reconstruct dinosaur history, including dinosaur flight. Link dinosaurs to reptilian transitions to water and the origins of birds. Locate and summarize a current news story about dinosaurs. Utilize a model to describe how geographic isolation can lead to alterations in allele frequencies and formation of a new species. Describe characteristics of dinosaurs, including claws, skulls, teeth, and feeding characteristics. Classify and provide examples of different groups of dinosaurs Make follow-up observations of corn seedlings and analyze information. Describe physical differences between Darwin’s finches, the role of intense competition in speciation, and speciation in the house mice of Madeira. Describe the newly published Alamosaurus fossil find, including the type of fossil found, its location, the dinosaur group this fossil belonged to, and its possible significance. Discuss the possible causes and impacts of previous mass extinctions. Explain how researchers are currently utilizing “wild” genes. Describe the primary causes of current extinctions, including examples of organisms. List possible solutions to reduce current extinction rates. Define coevolution and provide examples. List and provide examples of types of relationships between species. Explain how coevolution can impact impact biodiversity. Describe how microscopic organisms and viruses became a permanent part of other species Describe and provide specific examples of mammalian evolution. Examine characteristics and ancestry of primates. Take detailed notes on mammalian video footage, including monotremes and marsupials. List a variety of reasons for current species extinctions on the Hawaiian Islands. Analyze phylogenetic trees of lizard species on the Canary Islands. Provide specific examples of introduced species as well as threatened and endangered species. Locate, organize, and list information about an introduced species. Explain reciprocal altruism, including what it is, examples of organisms that may engage in this process, and why it may be beneficial for survival (impact fitness). Starting with “vertebral column and brain case,” list and describe the evolutionary changes that led to carnivores. (you are just responsible for these transitions, not all on the chart) Hypothesize why sexual reproduction is widespread in nature. 184 Exam #2 Exam #2 Portfolio #2 Exam #2 Exam #2 Exam #2 Portfolio #2 Exam #2 Exam #2 Exam #2 Exam #2 Exam #2 Exam #2 Exam #2 Exam #2 Exam #2 Exam #2 Exam #2 Exam #2 Portfolio #3 Exam #2 Exam #2 Exam #2 Portfolio #3 Exam #2 Exam #2 Final Exam (Lecture) 107 108 109 Behaviors (Lecture) 110 111 Structures and Behaviors (Recitation) 112 113 114 115 116 Innate and Learned Behaviors (Lab) 117 118 119 120 Readings (Bowerbirds, Crows, Jane Goodall) 121 122 123 Hominin (Lecture) 124 125 126 8 Modern Humans (Lecture) 127 128 129 130 Human Genetics (Recitation) 131 132 133 Describe how sexual reproduction has led to differences in males and females. Provide examples of sexual selection, including male competition, female choice, and unusual forms of sexual selection. Distinguish between innate and learned behaviors and provide examples of organism behaviors that are a combination of both. Provide specific examples of different types of innate and learned behaviors . Link animal behaviors to genetics and evolution. Model and describe relationships between predator and prey populations. Summarize the impact of chance on a population, as well as the significance of adaptations. Analyze and discuss predator-prey data. Provide examples of innate and learned behaviors that impact organism fitness. Describe the activity patterns of montane voles in relationship to circadian rhythms. Define invertebrates and describe the physical characteristics, habitats, and basic behaviors of planaria, earthworms, daphnia, sowbugs, and Madagascar hissing cockroaches. Distinguish between kinesis and taxis behaviors. Observe crickets and make detailed notes and drawings about physical structures and behaviors. Explain how male “satin” bowerbirds attract female bowerbirds. Describe recent research on crow cognition, including brain size, use of tools, and social interactions that may indicate the presence of imagination Describe the research of Jane Goodall, including specific chimpanzee behaviors. Describe the different types of evidence used to construct a timeline of human evolution. List the major transitions in human evolution, including the approximate times, fossil finds, and representative hominids. List human evolutionary constraints, the factors that may impact current human evolution. Provide examples of evolution in human parasites. Provide examples of human hosts evolving defenses against parasites. Discuss the hypothetical impact of larger brains, language and emotion on human evolution. Examine the impact of social behaviors on human survival. Study human traits to determine whether they follow Mendelian or non-Mendelian patterns of inheritance. Analyze human pedigrees to determine the genetic basis of inherited traits. Provide characteristics of the human genome, including karyotype and chromosomal features. Construct a human pedigree based on family data. 185 Final Exam Final Exam Final Exam Final Exam Final Exam Final Exam Final Exam Portfolio #3 Final Exam Final Exam Final Exam Final Exam Portfolio #3 Final Exam Final Exam Final Exam Final Exam Final Exam Final Exam Final Exam Final Exam Final Exam Final Exam Final Exam Final Exam Final Exam Portfolio #3 134 Parasites and Human Evolution (Lab) 135 136 137 138 Readings (Flores Man, Guinea Worm) 139 140 141 Human Inheritance (Lecture) 142 143 Genetic Technologies and Medicine (Lecture) 9 144 145 146 147 Genetic Disorders (Lab) 148 149 150 Readings (Gene Therapy, Stem Cells) 151 152 153 Genetic Engineering and Agriculture (Lecture) 154 155 156 10 157 Future Frontiers (Lecture) Genetic Technologies (Lab) 158 159 160 161 Describe basic structures of viruses, bacteria, protists, and animals that cause disease in humans, as well as how they impact the human body. Provide characteristics of Hominan, as well as research on Homo sapiens sapiens. Explain the difference between the four blood types and Rh factor and the relationship between blood types and human disease. Describe how incidence of malaria relates to frequency of the sickle cell anemia allele. Discuss how it may be too simplistic to label alleles as “good” or “bad” using sickle cell anemia as an example. Describe characteristics of Homo floresiensis. Describe “Guinea Worm,” including the countries where human infections are still occurring, the impact on the human body, and how infection by the parasite can be avoided. Describe human genetics, including number of chromosomes and the roles of meiosis, fertilization, and mitosis. Provide examples of variation in human traits, and possible explanations of those variations. Explain the genetic basis and symptoms of various human genetic disorders. List various types of genetic screening and the current use of gene therapy. Explain what stem cells are, where stem cells are found, the current use of stem cells, and potential uses of stem cells. Describe the eugenics movement, including the scientific flaws associated with the movement. Identify chromosomal disorders from karyotype data. Provide the genetic basic, inheritance patterns and symptoms for various gene-based genetic disorders. Examine pedigree and geographic data to study the genetic basis of lactose intolerance. Describe why humans lack the ability to produce vitamin C. Describe different approaches to gene therapy and the factors that have kept gene therapy from becoming an effective treatment for genetic disorders. List possible uses of stem cells and the technical problems that exist related to working with stem cells. Describe the basic techniques that are used in genetic engineering. List the steps involved in making genetically engineered crops. Define and provide examples of transgenic organisms. Describe the technique of cloning and provide examples of organisms that have been recently cloned. Describe the genetic basis and evolutionary changes in cancer List the genetic and evolutionary aspects of aging, as well as the potential to “cure” aging processes. Examine the potentials and pitfalls of reviving relic DNA. List the basic techniques and uses of genetic technologies. Provide examples of genetically modified organisms (GMOs), including successes and failures in producing chimeras. 186 Final Exam Finale Exam Final Exam Final Exam Portfolio #3 Final Exam Final Exam Final Exam Final Exam Final Exam Final Exam Final Exam Final Exam Final Exam Final Exam Final Exam Final Exam Final Exam Final Exam Final Exam Final Exam Final Exam Final Exam Final Exam Final Exam Final Exam Final Exam Fianl Exam 162 163 164 Readings (Cloning) 165 Describe how DNA fingerprinting can be used in criminal and paternity cases, as well as for tracking genetic disorders. Give examples of recent advancement in stem cell and cancer research. Discuss major themes in biology, and provide supporting examples from this course. Distinguish between DNA cloning, reproductive cloning, and therapeutic cloning and describe possible uses of cloning technologies. 187 Final Exam Final Exam Final Exam Final Exam 188