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The effect of aerobic continuous training and detraining on left
The effect of aerobic continuous training and detraining on left

... pressure. In training and competition, endurance-trained athletes sustain long intervals with high cardiac output, high heart rate, high stroke volume and a moderate increase in mean arterial blood pressure. Dynamic exercise imposes a volume load on the left ventricle. The cardiac output of trained ...
Long term survival study of patients with raised pulmonary arterial
Long term survival study of patients with raised pulmonary arterial

... the Student’s t-test for normally distributed, and the MannWhitney U-test for non-normally distributed continuous variables. The Chi-squared was employed for categorical variables. Unadjusted odds ratios (OR) with 95% confidence intervals (CI) were determined for hospitalization and causes of death. ...
Moderate Exercise Training Improves Survival and Ventricular
Moderate Exercise Training Improves Survival and Ventricular

... Key Words: survival 䡲 exercise 䡲 hypertrophy 䡲 valves 䡲 collagen ...
Continuous, non-invasive measurement of the - Heart
Continuous, non-invasive measurement of the - Heart

... Clinical studies have shown that limitation in exercise capacity is a strong predictor of cardiovascular and all cause mortality in diabetic patients with heart failure. Underlying pathophysiology is multifactorial and involves alterations in ventricular-vascular coupling consisting of cardiac chang ...
Circulation: Cardiovascular Quality and Outcomes Topic Review
Circulation: Cardiovascular Quality and Outcomes Topic Review

Paper Title (use style: paper title)
Paper Title (use style: paper title)

... The heart is the most important organs of the human body. This organ is a central pump and has the mission of create blood pressure that provides oxygen and nutrients to all cells of the body [1] [2]. The heart is a muscular organ with the size of a fist and comports four chambers: right atrium (or ...
Presentation of acute pulmonary oedema Definition
Presentation of acute pulmonary oedema Definition

...  Congestive cardiac failure (CCF): LVF and RVF co-exist, the latter usually secondary to the former  Cor pulmonale: RVF secondary to chronic lung pathology eg chronic obstructive pulmonary disease (COPD)  Low output cardiac failure: cardiac failure secondary to inadequate pumping and supply  Hig ...
Stroke - Canada.ca
Stroke - Canada.ca

... WHAT is a STROKE? A STROKE is a sudden loss of brain function caused by a sudden brain blood vessel blockage (ischemic stroke) or rupture (hemorrhagic stroke). Ischemic stroke is the most common type of stroke. Stroke can happen at any age, so know the signs and know what it looks like. ...
Advances in Arrhythmia and Electrophysiology
Advances in Arrhythmia and Electrophysiology

... CM signature of intermittent LBBB will be discussed in the following section along with right ventricular pacing. CM-related T-wave changes after intermittent right bundle branch block have not been described. The likely reason for that is that the delayed activation of the right ventricle produces ...
Crayfish Heart
Crayfish Heart

... Vertebrate hearts are myogenic; each muscle cell has intrinsic pacemaker properties. Each cell will beat in the absence of any neural input. The cells throughout the heart beat in a coordinated fashion because they are electrically coupled and beat at the same rate as the pacemaker cells in the sino ...
Long-Term Outcome of the Right Ventricular Outflow Tract Palliation
Long-Term Outcome of the Right Ventricular Outflow Tract Palliation

... One of the patients had coronary artery anomaly. All patients had spell on admission with active cyanosis (Table 1). Comparing laboratory and respiratory parameters 12 months after RVOT palliation (Table 2) showed a significant increase in arterial oxygen saturation (from 69.34 ± 13.07 to 86.29 ± 6. ...
Rheumatism is a systemic disease of a connective tissue of inflamm
Rheumatism is a systemic disease of a connective tissue of inflamm

... It is known from the anamnesis that 10 days ago he had quinsy. At physical examination: body temperature is 37,5’ C. The joints mentioned above are edematic,the body temperature above their surfaces is increased, tonsils are increased in size, there are purulent plugs in crypts. The left border of h ...
Images and Case Reports in Arrhythmia and Electrophysiology
Images and Case Reports in Arrhythmia and Electrophysiology

... potentials (Figure 4, left) and concealed entrainment indicated an endocardial circuit isthmus located between the aneurysm proximal border and the mitral valve. When the endocardial circuit was localized, radiofrequency energy was delivered interrupting the VT. Late potentials could be seen on that ...
A Case Series of Lyme Carditis with Complete Heart Block
A Case Series of Lyme Carditis with Complete Heart Block

... Chronic cases of Lyme have led to dilated cardiomyopathy in Europe, but there have been no reported cases of cardiomyopathies secondary to Lyme disease in the US.1,7 The most common cardiac manifestation of Lyme disease is fluctuating AV block.1-3,5 Almost all (98%) adults with Lyme carditis will ma ...
Modeling a Heart Pump
Modeling a Heart Pump

... from rather simple to very sophisticated numerical techniques, have been employed; see for example [9, 11, 16] and references therein for an overview of computational methods in cardiovascular fluid dynamics. A computationally cheap option to obtain information about the overall behavior of the card ...
Imaging of Coronary artery Bypass grafts and Stents
Imaging of Coronary artery Bypass grafts and Stents

... – 5 – 7 years post surgery – Atherosclerotic – Almost half of them may be asymptomatic ...
Heart failure in patients with preserved and - Heart
Heart failure in patients with preserved and - Heart

... information allowing optimisation of their treatment. ...
High Arteriovenous (AV) Access Flow and Cardiac Complications
High Arteriovenous (AV) Access Flow and Cardiac Complications

Beta-Blockers in the Management of Hypertension and/or Chronic
Beta-Blockers in the Management of Hypertension and/or Chronic

... in patients with hypertension [35]. This heart rate lowering causes a pseudoantihypertensive effect; that is, the central aortic pressure becomes less than the brachial pressure [7, 17, 18]. This phenomenon is thought to be one of mechanisms underlying the lower cardiovascular-protective effects of ...
Exercise Management
Exercise Management

... exercise because demands of the exercising muscle may be greater than the cardiac output available. •People with severe aortic stenosis should avoid vigorous physical activity because there is an increased risk of syncope or sudden death. ...
PDF - Romanian Journal of Cardiology
PDF - Romanian Journal of Cardiology

... prognosis, in both the short and the long term, independently of the size of infarction as evaluated by the levels of peak creatine kinase measured in the acute phase5. The authors mentioned as possible explanations for this finding the qualitative differences between the anterior and inferior walls ...
Phenotyping transgenic embryonic murine hearts using optical
Phenotyping transgenic embryonic murine hearts using optical

... The mouse is currently a widely used animal model for genetic manipulations, because it is a mammal with a four-chambered heart, a short gestation period (20 –21 days), and a completely mapped genome.1 The transcription factor hexamethylene-bis-acetamideinducible protein 1 (HEXIM1) is a tumor suppre ...
Mixed venous oxygen saturation predicts short-
Mixed venous oxygen saturation predicts short-

... are not well documented with regard to outcome. The aim of this study was to investigate SvO2 as a prognostic marker for short and long-term outcome in a large unselected CABG cohort and in subgroups with or without treatment for intraoperative heart failure. Methods: 2755 consecutive CABG patients ...
Full Paper - Daniel Burkhoff MD PhD
Full Paper - Daniel Burkhoff MD PhD

... present analysis, we sought to identify if there was a subgroup of patients who showed a response to CCM. Methods and Results: The protocol specified that multiregression analysis would be used to determine if baseline EF, NYHA functional class, pVO2, or etiology of heart failure influenced the impa ...
Computational modeling of passive myocardium
Computational modeling of passive myocardium

... approximately four-cell-thick sheets can easily slide along each while being stiffest in the direction of the large coiled perimysial fibers aligned with the long axes of the cardiomyocytes [3, 23, 25]. The underlying local orthotropy in the fiber-sheet system can still be modeled with an exponentia ...
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Myocardial infarction



Myocardial infarction (MI) or acute myocardial infarction (AMI), commonly known as a heart attack, occurs when blood flow stops to a part of the heart causing damage to the heart muscle. The most common symptom is chest pain or discomfort which may travel into the shoulder, arm, back, neck, or jaw. Often it is in the center or left side of the chest and lasts for more than a few minutes. The discomfort may occasionally feel like heartburn. Other symptoms may include shortness of breath, nausea, feeling faint, a cold sweat, or feeling tired. About 30% of people have atypical symptoms, with women more likely than men to present atypically. Among those over 75 years old, about 5% have had an MI with little or no history of symptoms. An MI may cause heart failure, an irregular heartbeat, or cardiac arrest.Most MIs occur due to coronary artery disease. Risk factors include high blood pressure, smoking, diabetes, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol intake, among others. The mechanism of an MI often involves the rupture of an atherosclerotic plaque, leading to complete blockage of a coronary artery. MIs are less commonly caused by coronary artery spasms, which may be due to cocaine, significant emotional stress, and extreme cold, among others. A number of tests are useful to help with diagnosis, including electrocardiograms (ECGs), blood tests, and coronary angiography. An ECG may confirm an ST elevation MI if ST elevation is present. Commonly used blood tests include troponin and less often creatine kinase MB.Aspirin is an appropriate immediate treatment for a suspected MI. Nitroglycerin or opioids may be used to help with chest pain; however, they do not improve overall outcomes. Supplemental oxygen should be used in those with low oxygen levels or shortness of breath. In ST elevation MIs treatments which attempt to restore blood flow to the heart are typically recommended and include angioplasty, where the arteries are pushed open, or thrombolysis, where the blockage is removed using medications. People who have a non-ST elevation myocardial infarction (NSTEMI) are often managed with the blood thinner heparin, with the additional use angioplasty in those at high risk. In people with blockages of multiple coronary arteries and diabetes, bypass surgery (CABG) may be recommended rather than angioplasty. After an MI, lifestyle modifications, along with long term treatment with aspirin, beta blockers, and statins, are typically recommended.Worldwide, more than 3 million people have ST elevation MIs and 4 million have NSTEMIs each year. STEMIs occur about twice as often in men as women. About one million people have an MI each year in the United States. In the developed world the risk of death in those who have had an STEMI is about 10%. Rates of MI for a given age have decreased globally between 1990 and 2010.
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