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EXPERIENCE, INSIGHTS AND TECHNIQUES FOR CARDIAC
EXPERIENCE, INSIGHTS AND TECHNIQUES FOR CARDIAC

... really matter whether the heart is beating or not, functioning or nonfunctioning. In the OPCAB mode any variance from normal functioning will need to be identified in real-time, preferably beat-to-beat, allowing the earliest possible therapeutic and procedural response. An arterial line in combinati ...
The Apical First Heart Sound as an Aid in the Diagnosis
The Apical First Heart Sound as an Aid in the Diagnosis

... Splitting of the first hleart sounid was first lescribed by Potai.n'111 in the nineteenth century. He advaneed nio pLysiologic explanation for this finding, althouitgh he believed that the first heart sounlld was produced by closure of the atrioventrieular valves. In 1925, Katz" demnonistrated exper ...
Heart Failure With Normal Ejection Fraction
Heart Failure With Normal Ejection Fraction

... been attributed to impaired myocardial relaxation and has traditionally been described as diastolic HF [3–5]. However, this designation implies that a single pathophysiologic pathway explains what has become increasingly recognized as a syndrome comprising a heterogeneous group of patients. The como ...
Evolutionary origin of cardiac malformations
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... extension of my previous study (1) of common cardiac malformations that occur as isolated anomalies and occasionally in syndromes of multiple organ congenital anomalies in humans and many other placental mammals . I presented evidence that the origin of these malformations dated back to the evolutio ...
Lesson №1 Anatomy of cardiovascular system. The coronary
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... 2. Specifity of the test with dosed physical load in the diagnosis of IHD is highest: 1) in women; 2) young men; 3) in older and middle-aged men; 4) There is no right answer 5) no significant difference 3. The most informative ECG lead during exercise stress test in order to diagnose coronary artery ...
Inhibition of TGF-β1 by eNOS gene transfer provides cardiac
Inhibition of TGF-β1 by eNOS gene transfer provides cardiac

... Abstract: It has been observed that the incidence of heart failure and Brugada syndrome are higher in men, while women are more likely to have QT interval prolongation and develop torsades de pointes (TdP). Over the past decade, new studies have improved our understanding of the mechanisms of abnorm ...
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Complete Article - Journal of Morphological Science
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... of the sinuatrial nodal branch (SNA). In this work, we examined the anatomy of this atrial branch using cineangiography. We reviewed the records of 100 cineangiocoronariographies done between October 1991 and November 1992 in the teaching hospital of the Faculty of Medicine of Triângulo Mineiro. The ...
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Involvement of mitogen-activated protein kinases in adriamycin

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Profound Bradycardia With Decreased PEEP
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ECG interpretations
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Extreme respiratory sinus arrhythmia enables overwintering black bear
Extreme respiratory sinus arrhythmia enables overwintering black bear

... humans has been proposed for medical treatment and/or prolonged space travel [9]. Clinical applications of a reduced metabolic state typical of overwintering bears include treatment for human heart failure, stroke, myocardial infarction, and extending the duration of whole organ ischemia prior to tr ...
PDF - Circulation: Arrhythmia and Electrophysiology
PDF - Circulation: Arrhythmia and Electrophysiology

... beats.16 The original assumption of total independence (protection) of parasystolic focus from extraneous beats is no longer considered true. It is now evident that any pacemaker connected to the surrounding tissues by an area of depressed excitability producing entrance conduction disturbances whil ...
Functions of the Circulatory System
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... The Heart’s Blood Supply Heart muscle needs a constant supply of oxygen and nutrients. A pair of blood vessels called coronary arteries, which branch from the aorta and run through heart tissue, supply blood to the heart muscle. Coronary arteries and the vessels that branch from them are relatively ...
Accuracy of manual QRS duration assessment
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... 12-lead ECG with a QRSd 120 ms’.6 Although there is evidence for QRSd assessment to be based on the maximal QRSd in one or two leads, this was precisely the area where manual assessment demonstrated poorest concordance with the computer-calculated QRSd. In fact, apart from the ‘negative control’, a ...
Labetalol acls
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Arrhythmogenic Right Ventricular Dysplasia / Cardiomyopathy : A
Arrhythmogenic Right Ventricular Dysplasia / Cardiomyopathy : A

... to have cardiomegaly. His history was negative for cardiac symptoms except for one brief presyncopal spell lasting a few seconds while playing basketball as an adolescent. He had continued to engage in vigorous activity after that without any discomfort. His older brother had died suddenly at the ag ...
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... ECG Waveform Characteristics • Waveform usually contains three distinct segments P wave (atrial excitation) ...
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... Males and females exhibit different rates of central obesity, cardiovascular disease and diabetes. Furthermore, altered concentrations of sex steroid hormones can lead to altered rates of these diseases in the afflicted populations, suggesting these hormones can affect metabolism and, in the long te ...
Trisomy 13 Facts
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... Trisomy 13 syndrome is a disorder of human chromosomes which occurs in approximately 1 in 10,000 live born infants. Trisomy refers to three copies of a chromosome instead of the normal two and in Trisomy 13 there is the presence of an extra #13 chromosome. Approximately 80% of infants with Trisomy 1 ...
Stable myocardial specific AAV6-S100A1 gene therapy results in
Stable myocardial specific AAV6-S100A1 gene therapy results in

... S100A1 is highly and preferentially expressed in the healthy heart, whereas it is found to be significantly downregulated in HF.12,13,16 Previous studies by our laboratory have shown that targeting S100A1 expression in HF is a promising strategy to recover deranged intracellular Ca2⫹ cycling and to ...
to the S-ICD Brochure
to the S-ICD Brochure

... How did you decide on the S-ICD System? “The cardiologist said I needed the implanted defibrillator to manage my high risk of sudden cardiac death. They also gave me the great option of the S-ICD System, an implanted device that didn’t go into the veins, which could cause me to have a blood clot iss ...
The Heart
The Heart

...  Blood in the heart chambers does not nourish the myocardium  The heart has its own nourishing circulatory system consisting of  Coronary arteries—branch from the aorta to supply the heart muscle with oxygenated blood  Cardiac veins—drain the myocardium of blood  Coronary sinus—a large vein on ...
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Myocardial infarction



Myocardial infarction (MI) or acute myocardial infarction (AMI), commonly known as a heart attack, occurs when blood flow stops to a part of the heart causing damage to the heart muscle. The most common symptom is chest pain or discomfort which may travel into the shoulder, arm, back, neck, or jaw. Often it is in the center or left side of the chest and lasts for more than a few minutes. The discomfort may occasionally feel like heartburn. Other symptoms may include shortness of breath, nausea, feeling faint, a cold sweat, or feeling tired. About 30% of people have atypical symptoms, with women more likely than men to present atypically. Among those over 75 years old, about 5% have had an MI with little or no history of symptoms. An MI may cause heart failure, an irregular heartbeat, or cardiac arrest.Most MIs occur due to coronary artery disease. Risk factors include high blood pressure, smoking, diabetes, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol intake, among others. The mechanism of an MI often involves the rupture of an atherosclerotic plaque, leading to complete blockage of a coronary artery. MIs are less commonly caused by coronary artery spasms, which may be due to cocaine, significant emotional stress, and extreme cold, among others. A number of tests are useful to help with diagnosis, including electrocardiograms (ECGs), blood tests, and coronary angiography. An ECG may confirm an ST elevation MI if ST elevation is present. Commonly used blood tests include troponin and less often creatine kinase MB.Aspirin is an appropriate immediate treatment for a suspected MI. Nitroglycerin or opioids may be used to help with chest pain; however, they do not improve overall outcomes. Supplemental oxygen should be used in those with low oxygen levels or shortness of breath. In ST elevation MIs treatments which attempt to restore blood flow to the heart are typically recommended and include angioplasty, where the arteries are pushed open, or thrombolysis, where the blockage is removed using medications. People who have a non-ST elevation myocardial infarction (NSTEMI) are often managed with the blood thinner heparin, with the additional use angioplasty in those at high risk. In people with blockages of multiple coronary arteries and diabetes, bypass surgery (CABG) may be recommended rather than angioplasty. After an MI, lifestyle modifications, along with long term treatment with aspirin, beta blockers, and statins, are typically recommended.Worldwide, more than 3 million people have ST elevation MIs and 4 million have NSTEMIs each year. STEMIs occur about twice as often in men as women. About one million people have an MI each year in the United States. In the developed world the risk of death in those who have had an STEMI is about 10%. Rates of MI for a given age have decreased globally between 1990 and 2010.
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