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Left ventricular long-axis diastolic function is
Left ventricular long-axis diastolic function is

... quantification of myocardial velocities from different ventricular segments. Tissue Doppler data can be acquired in digital format from every region of the ventricles at the same time as grey-scale images are acquired, and the data can then be analysed off-line after an echo study [4]. This allows r ...
Tricuspid Valve
Tricuspid Valve

... lining of endocardial cells o Cardiac jelly, extensive extracellular matrix (ECM), separates the two layers o Cardiac jelly expands to form cardiac cushions at the sites of future valves  Outflow track (OT) valves = aortic and pulmonic valves  Final valves derived from endothelial-mesenchymal cell ...
ENDOCRINE SYSTEM TOPICS
ENDOCRINE SYSTEM TOPICS

... Since  the  thyroid  gland  makes  mostly  T4,  and  very  little  T3,  each  cell  must  take  in  the  T4  and  use  an  enzyme to cut off an iodine to make their own T3. Under normal conditions, the iodine that the enzyme  removes  makes  T3  that  increases  metabolism.  Recently  it  has  been  ...
PDF - Circulation
PDF - Circulation

... decline with age.1"'12 There are fewer data in humans, and many prior studies have been confounded by the failure to rigorously exclude underlying occult cardiovascular disease, which might alter 13-adrenergic responses. Available studies in humans have documented reduced blood pressure or venodilat ...
Full Text  - Asian Journal of Sports Medicine
Full Text - Asian Journal of Sports Medicine

... Data primarily from Framingham’s heart study have shown left ventricular hypertrophy (LVH) either physiologic or pathologic is an independent risk factor for arrhythmia and sudden cardiac death [13, 14]. Trans thoracic Echocardiography is the most useful noninvasive tool for evaluation of LVH and my ...
Full Paper - Daniel Burkhoff MD PhD
Full Paper - Daniel Burkhoff MD PhD

... because these patients as a whole may have different underlying etiologies and varied numbers and severity of comorbid conditions, so that different therapies may be needed to address different patient subgroups. However, regardless of etiology or comorbid conditions, an overarching pathophysiologic ...
Document
Document

... As the case is presented, mark off the required information in the appropriate fields on your Macstrak form. At the end of each case study, the form will be reviewed with the correct answers supplied. ...
Lecture 7 Chapter 13:Therapeutic/Prosthetic
Lecture 7 Chapter 13:Therapeutic/Prosthetic

... 6. Draw the 2 possible of paddles placement in the case of external electrodes. 7. Can one use a defibrillator with a patient on a OR table? Why? ...
Circulation Research
Circulation Research

... The nature and location of the cardiac receptors that send their afferent fibers centrally in the pericoronary nerve is only partially known. Brown and Malliani (unpublished observations) found some afferent fibers in the third thoracic ramus communicans excited by increases or decreases in coronary ...
Increased plasma levels of adrenomedullin in patients with
Increased plasma levels of adrenomedullin in patients with

... has been detected in human plasma, and human adrenomedullin messenger RNA is reported to be highly expressed not only in pheochromocytoma, but also in the normal adrenal medulla, kidney, lung and ventricle (2). Recent studies (3,4) report that vascular smooth muscle cells possess specific adrenomedu ...
The formation and function of the cardiac conduction system
The formation and function of the cardiac conduction system

Full Text
Full Text

... the hypothesis that HF is a state of deficiency of active BNP 1-32, thus accounting partially for the discrepancy between the high immunoreactive BNP levels and the lack of biological activity in severe HF. However, it has to be pointed out that all these studies used plasma from patients with New Y ...
stroke volume during incremental exercise Heart rate deflection
stroke volume during incremental exercise Heart rate deflection

... Beyond this methodological criticism, the cause of the HRDP phenomena can also be questioned. Although left ventricular ejection fraction (LVEF) increased from rest to the LT in healthy male subjects (12, 25, 26), the break point in the HR-work performance curve became less pronounced or was absent ...
A brief glossary of the most used cardiac acronyms and medical
A brief glossary of the most used cardiac acronyms and medical

here
here

... animals and humans consisted of 8 –12 equally spaced electrodes, with a micromanometer mounted between electrodes 3 and 4 so it would lie within the LV. The catheter was placed with its distal tip in the LV apex, and proximal electrode just beyond the aortic valve. A high-frequency (⬃20 kHz), lowamp ...
Intracoronary KAI-9803 as an Adjunct to Primary Percutaneous Coronary Intervention... Acute ST-Elevation Myocardial Infarction
Intracoronary KAI-9803 as an Adjunct to Primary Percutaneous Coronary Intervention... Acute ST-Elevation Myocardial Infarction

... age, presented with at least 30 minutes of ischemic chest pain and within 6 hours of symptom onset, had persistent ST-segment elevation of ≥ 0.2 mV in at least 2 contiguous precordial leads indicating anterior MI location (leads V1–V4), had complete occlusion of the left anterior descending artery ( ...
Heart Lung Transplant
Heart Lung Transplant

... fibrosis (14%). Eisenmenger syndrome is a form of congenital heart disease in which systemicto-pulmonary shunting leads to pulmonary vascular resistance. Eventually, pulmonary hypertension may lead to a reversal of the intracardiac shunting and inadequate peripheral oxygenation, or cyanosis.1 Howeve ...
Left Ventricular Systolic Longitudinal Function, Afterload and
Left Ventricular Systolic Longitudinal Function, Afterload and

... Objective: The aim of this study was to evaluate SLF alterations and their relationship with afterload and myocardial contractility in patients with severe AS. Methods: One hundred and one patients with severe AS (AVA <1 cm2) and 63 normal control subjects were studied with Doppler echocardiography. ...
Left Atrial Appendage: Useless or Priceless?
Left Atrial Appendage: Useless or Priceless?

... As it is more distensible than the left atrium itself it can act as a decompression chamber when left atrial pressure is high. Animal experiments have shown that eliminating access to the LAA results in an increase in the size and mean pressure in the left atrium. ...
Ventricular Assist Devices
Ventricular Assist Devices

... *NYHA Class IV = inability to carry on any activity without symptoms; symptoms may be present at rest 4. For use to provide temporary left sided mechanical circulatory support as a bridge to cardiac transplantation for pediatric patients who meet both of the following criteria: a. NYHA Class IV end- ...
Systolic and Diastolic Myocardial Mechanics in Patients with
Systolic and Diastolic Myocardial Mechanics in Patients with

... elevated LV filling pressures. However, that is not to say that the observed systolic abnormalities are necessarily the cause of elevated LV filling pressure, as it has been recognized in different populations that the main pathophysiologic abnormality in patients with clinical heart failure and pre ...
Ashburn DA, Blackstone EH, Wells WJ, Jonas RA, Pigula FA
Ashburn DA, Blackstone EH, Wells WJ, Jonas RA, Pigula FA

... ventricular septum were entered into a prospective study by 33 institutions. Competing risks analysis was used to demonstrate the prevalence of 6 end states. Factors predictive of attaining each end state were identified by means of multivariable analysis with bootstrap validation. Results: Overall ...
Evaluation of right and left ventricular function
Evaluation of right and left ventricular function

... strain 1.6 percentage points (PP) (COV = 8.2%), the same in various locations of the heart. The inter-individual error was, as expected, greater, 2.5 PP (COV = 12.7%), with 2D strain error in the mid level of the RV being significantly greater expressed in absolute but not in relative terms (3.94 PP ...
NCC Pediatrics Continuity Clinic Curriculum
NCC Pediatrics Continuity Clinic Curriculum

... May indicate CHF, poor cardiac fitness, or a genetic disorder or syndrome; poor weight gain most commonly reflects decreased cardiac output or left-to-right shunts with pulmonary hypertension ...
Cardiology in the Young Atrial structure in the presence of visceral
Cardiology in the Young Atrial structure in the presence of visceral

... which underscore the development of symmetry as opposed to lateralisation within the bodily organs. The evidence is becoming increasingly more convincing that concepts of the five-segmented primary heart tube are unduly simplistic. When the heart tube is first formed, the convincing studies of de la ...
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Myocardial infarction



Myocardial infarction (MI) or acute myocardial infarction (AMI), commonly known as a heart attack, occurs when blood flow stops to a part of the heart causing damage to the heart muscle. The most common symptom is chest pain or discomfort which may travel into the shoulder, arm, back, neck, or jaw. Often it is in the center or left side of the chest and lasts for more than a few minutes. The discomfort may occasionally feel like heartburn. Other symptoms may include shortness of breath, nausea, feeling faint, a cold sweat, or feeling tired. About 30% of people have atypical symptoms, with women more likely than men to present atypically. Among those over 75 years old, about 5% have had an MI with little or no history of symptoms. An MI may cause heart failure, an irregular heartbeat, or cardiac arrest.Most MIs occur due to coronary artery disease. Risk factors include high blood pressure, smoking, diabetes, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol intake, among others. The mechanism of an MI often involves the rupture of an atherosclerotic plaque, leading to complete blockage of a coronary artery. MIs are less commonly caused by coronary artery spasms, which may be due to cocaine, significant emotional stress, and extreme cold, among others. A number of tests are useful to help with diagnosis, including electrocardiograms (ECGs), blood tests, and coronary angiography. An ECG may confirm an ST elevation MI if ST elevation is present. Commonly used blood tests include troponin and less often creatine kinase MB.Aspirin is an appropriate immediate treatment for a suspected MI. Nitroglycerin or opioids may be used to help with chest pain; however, they do not improve overall outcomes. Supplemental oxygen should be used in those with low oxygen levels or shortness of breath. In ST elevation MIs treatments which attempt to restore blood flow to the heart are typically recommended and include angioplasty, where the arteries are pushed open, or thrombolysis, where the blockage is removed using medications. People who have a non-ST elevation myocardial infarction (NSTEMI) are often managed with the blood thinner heparin, with the additional use angioplasty in those at high risk. In people with blockages of multiple coronary arteries and diabetes, bypass surgery (CABG) may be recommended rather than angioplasty. After an MI, lifestyle modifications, along with long term treatment with aspirin, beta blockers, and statins, are typically recommended.Worldwide, more than 3 million people have ST elevation MIs and 4 million have NSTEMIs each year. STEMIs occur about twice as often in men as women. About one million people have an MI each year in the United States. In the developed world the risk of death in those who have had an STEMI is about 10%. Rates of MI for a given age have decreased globally between 1990 and 2010.
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