reduced left ventricular systolic function differentiate between
... increasing age and with decreasing LVEF (p < 0.05). A predicted concentration of NT-proBNP (corrected for age, sex, and serum creatinine) was determined for each patient. In patients with an NT-proBNP value less than predicted, the probability of having an LVEF of > 40% was more than 97%. This proba ...
... increasing age and with decreasing LVEF (p < 0.05). A predicted concentration of NT-proBNP (corrected for age, sex, and serum creatinine) was determined for each patient. In patients with an NT-proBNP value less than predicted, the probability of having an LVEF of > 40% was more than 97%. This proba ...
Infective Endocarditis
... is best to demonstrate anterior abscess of the aortic annulus [9]. Embolic events are common and symptomatic in 25% of cases with half incidentally found [10,11]. The risk of embolization is related to vegetation size. There is strong evidence that early surgery helps reduces embolic risk. When a ve ...
... is best to demonstrate anterior abscess of the aortic annulus [9]. Embolic events are common and symptomatic in 25% of cases with half incidentally found [10,11]. The risk of embolization is related to vegetation size. There is strong evidence that early surgery helps reduces embolic risk. When a ve ...
042601 Cardiac Resuscitation
... 2. Shock using 200 J, 200–300 J, and then 360 J.† 3. Intubate the trachea and confirm that tube placement is correct; establish intravenous catheter access. 4. Administer epinephrine (1 mg by intravenous push, repeated every 3–5 min) or vasopressin (a single dose of 40 U intravenously). 5. Shock usi ...
... 2. Shock using 200 J, 200–300 J, and then 360 J.† 3. Intubate the trachea and confirm that tube placement is correct; establish intravenous catheter access. 4. Administer epinephrine (1 mg by intravenous push, repeated every 3–5 min) or vasopressin (a single dose of 40 U intravenously). 5. Shock usi ...
lxxi. the isolation of histamine from
... The heart is not an exception. In fact, it yields an extract with powerful depressor activity. The marked similarity in the physiological behaviour of tissue extracts and of solutions of histamine gave rise to the view that histamine was present in these extracts, a view which has been confirmed rec ...
... The heart is not an exception. In fact, it yields an extract with powerful depressor activity. The marked similarity in the physiological behaviour of tissue extracts and of solutions of histamine gave rise to the view that histamine was present in these extracts, a view which has been confirmed rec ...
Primary synovial sarcoma of the right heart involving the tricuspid
... translocations, the cytogenetic hallmark of SS. More than 90 % of SS present this translocation, which gives rise to a fusion gene, SS18 (SYT)-SSX (SSX1 or SSX2, or both) [5–17], whereas MPNST and carcinosarcoma lack SS18SSX fusions. The SS18 rearrangement was also observed in this case, and MPNST a ...
... translocations, the cytogenetic hallmark of SS. More than 90 % of SS present this translocation, which gives rise to a fusion gene, SS18 (SYT)-SSX (SSX1 or SSX2, or both) [5–17], whereas MPNST and carcinosarcoma lack SS18SSX fusions. The SS18 rearrangement was also observed in this case, and MPNST a ...
Pulse pressure as a haemodynamic variable in systolic heart failure
... to have symptoms of heart failure at rest despite optimal therapy, within the 2 months before randomisation or have been recently admitted to hospital with worsening heart failure. Hospitalised patients were excluded, thus the study population was those with advanced but stable chronic heart failure ...
... to have symptoms of heart failure at rest despite optimal therapy, within the 2 months before randomisation or have been recently admitted to hospital with worsening heart failure. Hospitalised patients were excluded, thus the study population was those with advanced but stable chronic heart failure ...
Progress toward controlling in vivo fibrillating sheep
... to a desired target state by applying only minute perturbations to the system. The control strategies are quite general and do not require a detailed mathematical model of the system. The key idea is to design perturbations that direct the system near to or stabilize it about one of the unstable per ...
... to a desired target state by applying only minute perturbations to the system. The control strategies are quite general and do not require a detailed mathematical model of the system. The key idea is to design perturbations that direct the system near to or stabilize it about one of the unstable per ...
Cardiovascular Pharmacology
... The SVTs are generally benign (that is, non-life-threatening) tachycardias that either arise in the atria (that is, “supra” the ventricles), or involve the atria in the mechanism of the tachycardia. Many SVTs are due to extra, abnormal electrical connections between the atria and the ventricles. Ind ...
... The SVTs are generally benign (that is, non-life-threatening) tachycardias that either arise in the atria (that is, “supra” the ventricles), or involve the atria in the mechanism of the tachycardia. Many SVTs are due to extra, abnormal electrical connections between the atria and the ventricles. Ind ...
Simulation Study of the Electrophysiological Mechanisms for Heart
... HF phenotype, we performed a sensitivity analysis of the proposed HF model. This study provides understanding of how the reported variability in HF remodeling might modulate the main EP characteristics in HF. The properties of the ionic currents considered in the sensitivity study were the maximal c ...
... HF phenotype, we performed a sensitivity analysis of the proposed HF model. This study provides understanding of how the reported variability in HF remodeling might modulate the main EP characteristics in HF. The properties of the ionic currents considered in the sensitivity study were the maximal c ...
AHA Scientific Statement: Drugs That May Cause or Exacerbate
... eart failure (HF) remains the leading discharge diagnosis among patients ≥65 years of age. The estimated cost for treatment of HF in Medicare recipients is $31 billion and is expected to increase to $53 billion by 2030.1 Hospitalization for HF is the largest segment of those costs. It is likely that ...
... eart failure (HF) remains the leading discharge diagnosis among patients ≥65 years of age. The estimated cost for treatment of HF in Medicare recipients is $31 billion and is expected to increase to $53 billion by 2030.1 Hospitalization for HF is the largest segment of those costs. It is likely that ...
McSharry P.E., Clifford G.D., Tarassenko L., Smith L.
... in a large database such as the Physionet database [8]. While this gives the operator an indication of the accuracy of a given algorithm when applied to real data, it is difficult to infer how the performance would vary in different clinical settings with a range of noise levels and sampling frequen ...
... in a large database such as the Physionet database [8]. While this gives the operator an indication of the accuracy of a given algorithm when applied to real data, it is difficult to infer how the performance would vary in different clinical settings with a range of noise levels and sampling frequen ...
Cognitive function is associated with impaired heart rate
... ventricular ectopic beats and noise were excluded from the signal using linear interpolation. All recordings were screened for atrial fibrillation (AF) using criteria from the European society of cardiology (ESC ...
... ventricular ectopic beats and noise were excluded from the signal using linear interpolation. All recordings were screened for atrial fibrillation (AF) using criteria from the European society of cardiology (ESC ...
To or view the full scientific statement, click here.
... eart failure (HF) remains the leading discharge diagnosis among patients ≥65 years of age. The estimated cost for treatment of HF in Medicare recipients is $31 billion and is expected to increase to $53 billion by 2030.1 Hospitalization for HF is the largest segment of those costs. It is likely that ...
... eart failure (HF) remains the leading discharge diagnosis among patients ≥65 years of age. The estimated cost for treatment of HF in Medicare recipients is $31 billion and is expected to increase to $53 billion by 2030.1 Hospitalization for HF is the largest segment of those costs. It is likely that ...
PPT Ch 11Circulatory System
... •Superior and inferior venae cavae dump blood into the right atrium •From right atrium, through the tricuspid valve, blood travels to the right ventricle •From the right ventricle, blood leaves the heart as it passes through the pulmonary semilunar valve into the pulmonary trunk •Pulmonary trunk spl ...
... •Superior and inferior venae cavae dump blood into the right atrium •From right atrium, through the tricuspid valve, blood travels to the right ventricle •From the right ventricle, blood leaves the heart as it passes through the pulmonary semilunar valve into the pulmonary trunk •Pulmonary trunk spl ...
Diastolic Dysfunction and Its Management in Elderly Patients
... Positive inotropic agents (such as digoxin) are generally not recommended in the treatment of patients with isolated diastolic CHF, because left ventricular ejection fraction is preserved in these patients. However, results of the Digitalis Investigation Group trial16 suggest that even patients with ...
... Positive inotropic agents (such as digoxin) are generally not recommended in the treatment of patients with isolated diastolic CHF, because left ventricular ejection fraction is preserved in these patients. However, results of the Digitalis Investigation Group trial16 suggest that even patients with ...
Circulatory Power Point File
... •Superior and inferior venae cavae dump blood into the right atrium •From right atrium, through the tricuspid valve, blood travels to the right ventricle •From the right ventricle, blood leaves the heart as it passes through the pulmonary semilunar valve into the pulmonary trunk •Pulmonary trunk spl ...
... •Superior and inferior venae cavae dump blood into the right atrium •From right atrium, through the tricuspid valve, blood travels to the right ventricle •From the right ventricle, blood leaves the heart as it passes through the pulmonary semilunar valve into the pulmonary trunk •Pulmonary trunk spl ...
Biventricular implantable cardioverter defibrillator use in
... recurrent ‘breakthrough’ ventricular tachycardia. The baseline ECG during right ventricular pacing demonstrated a paced QRS duration of >200 ms with a left bundle branch block pattern. We therefore proceeded to biventricular ICD implantation. A Medtronic GEM DR dual chamber ICD (Medtronic Inc, Minne ...
... recurrent ‘breakthrough’ ventricular tachycardia. The baseline ECG during right ventricular pacing demonstrated a paced QRS duration of >200 ms with a left bundle branch block pattern. We therefore proceeded to biventricular ICD implantation. A Medtronic GEM DR dual chamber ICD (Medtronic Inc, Minne ...
Twist Mechanics of the Left Ventricle
... For example, LV systolic twisting and untwisting can almost double with short-term exercise because of augmented rotation of both apical and basal levels (40), storing additional potential energy that is released for improving diastolic suction (41,42). Long-term exercise training may, however, redu ...
... For example, LV systolic twisting and untwisting can almost double with short-term exercise because of augmented rotation of both apical and basal levels (40), storing additional potential energy that is released for improving diastolic suction (41,42). Long-term exercise training may, however, redu ...
Cardiac Iodine-123 Metaiodobenzylguanidine Imaging
... Follow-up. All of the study patients were then followed up prospectively in our hospital at least once a month by clinicians who were not aware of the results of cardiac MIBG imaging, SAECG, HRV, or QT dispersion. The primary end point of this study was SCD, defined as witnessed cardiac arrest or de ...
... Follow-up. All of the study patients were then followed up prospectively in our hospital at least once a month by clinicians who were not aware of the results of cardiac MIBG imaging, SAECG, HRV, or QT dispersion. The primary end point of this study was SCD, defined as witnessed cardiac arrest or de ...
Effect of skeletal muscle demand on
... exercise is how well the respiratory muscles compete with locomotor muscles for blood flow. Historically, the influence of respiratory muscle work on the cardiovascular system has been regarded as having a minimal role. However, during strenuous exercise in highly fit humans, when the level of venti ...
... exercise is how well the respiratory muscles compete with locomotor muscles for blood flow. Historically, the influence of respiratory muscle work on the cardiovascular system has been regarded as having a minimal role. However, during strenuous exercise in highly fit humans, when the level of venti ...
Lucía Romero, Esther Pueyo, Martin Fink and Blanca Rodríguez
... in the proarrhythmic responses associated with ion current alterations that result in APD prolongation. In both cases variability arises not only through variability in one particular ion channel expression but also because of the complex electrophysiological interplay in which ion channel inhibitio ...
... in the proarrhythmic responses associated with ion current alterations that result in APD prolongation. In both cases variability arises not only through variability in one particular ion channel expression but also because of the complex electrophysiological interplay in which ion channel inhibitio ...
Pak Heart J - Pakistan Heart Journal
... currently used in Egypt are based on standards of values of other countries. Estimations can be made with different modalities. M-mode echocardiography is widely used in clinical and scientific practice, despite its lacking accuracy and reproducibility.1-3 Age, height, weight, and sex emerged as the ...
... currently used in Egypt are based on standards of values of other countries. Estimations can be made with different modalities. M-mode echocardiography is widely used in clinical and scientific practice, despite its lacking accuracy and reproducibility.1-3 Age, height, weight, and sex emerged as the ...
the Cardiology Advanced Training Curriculum
... Graduates from this training program will be equipped to function effectively within the current and emerging professional, medical and societal contexts. At the completion of the Advanced Training Program in Adult Cardiology, as defined by this curriculum, it is expected that a new Fellow will have ...
... Graduates from this training program will be equipped to function effectively within the current and emerging professional, medical and societal contexts. At the completion of the Advanced Training Program in Adult Cardiology, as defined by this curriculum, it is expected that a new Fellow will have ...
Myocardial infarction
Myocardial infarction (MI) or acute myocardial infarction (AMI), commonly known as a heart attack, occurs when blood flow stops to a part of the heart causing damage to the heart muscle. The most common symptom is chest pain or discomfort which may travel into the shoulder, arm, back, neck, or jaw. Often it is in the center or left side of the chest and lasts for more than a few minutes. The discomfort may occasionally feel like heartburn. Other symptoms may include shortness of breath, nausea, feeling faint, a cold sweat, or feeling tired. About 30% of people have atypical symptoms, with women more likely than men to present atypically. Among those over 75 years old, about 5% have had an MI with little or no history of symptoms. An MI may cause heart failure, an irregular heartbeat, or cardiac arrest.Most MIs occur due to coronary artery disease. Risk factors include high blood pressure, smoking, diabetes, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol intake, among others. The mechanism of an MI often involves the rupture of an atherosclerotic plaque, leading to complete blockage of a coronary artery. MIs are less commonly caused by coronary artery spasms, which may be due to cocaine, significant emotional stress, and extreme cold, among others. A number of tests are useful to help with diagnosis, including electrocardiograms (ECGs), blood tests, and coronary angiography. An ECG may confirm an ST elevation MI if ST elevation is present. Commonly used blood tests include troponin and less often creatine kinase MB.Aspirin is an appropriate immediate treatment for a suspected MI. Nitroglycerin or opioids may be used to help with chest pain; however, they do not improve overall outcomes. Supplemental oxygen should be used in those with low oxygen levels or shortness of breath. In ST elevation MIs treatments which attempt to restore blood flow to the heart are typically recommended and include angioplasty, where the arteries are pushed open, or thrombolysis, where the blockage is removed using medications. People who have a non-ST elevation myocardial infarction (NSTEMI) are often managed with the blood thinner heparin, with the additional use angioplasty in those at high risk. In people with blockages of multiple coronary arteries and diabetes, bypass surgery (CABG) may be recommended rather than angioplasty. After an MI, lifestyle modifications, along with long term treatment with aspirin, beta blockers, and statins, are typically recommended.Worldwide, more than 3 million people have ST elevation MIs and 4 million have NSTEMIs each year. STEMIs occur about twice as often in men as women. About one million people have an MI each year in the United States. In the developed world the risk of death in those who have had an STEMI is about 10%. Rates of MI for a given age have decreased globally between 1990 and 2010.