Etiology of Valvular Heart Disease in the 21st Century
... valvular vegetation formation which can involve all four valves, but left-sided lesions are more common. Vegetations consist of platelets within a fibrin mesh and a few inflammatory cells. Thromboembolic phenomena may occur. Right heart involvement with infective endocarditis occurs in patients who ...
... valvular vegetation formation which can involve all four valves, but left-sided lesions are more common. Vegetations consist of platelets within a fibrin mesh and a few inflammatory cells. Thromboembolic phenomena may occur. Right heart involvement with infective endocarditis occurs in patients who ...
Quantification of the Contribution of Cardiac and Arterial - VU-dare
... was considerably lower in the latter group than in all others, leading to higher values for peripheral resistance and lower values for total arterial compliance. Unfortunately, Roman et al14 did not report SV, limiting a more detailed and direct comparison of both data sets. The LV response to hyper ...
... was considerably lower in the latter group than in all others, leading to higher values for peripheral resistance and lower values for total arterial compliance. Unfortunately, Roman et al14 did not report SV, limiting a more detailed and direct comparison of both data sets. The LV response to hyper ...
Digoxin Uptake, Receptor Heterogeneity, and Inotropic Response in
... congestive heart failure because the inhibition of Na⫹/K⫹ATPase (sodium pump), which serves as a functional receptor for digitalis, results in an increase in positive inotropy. Binding of digitalis drugs, such as digoxin, to the catalytic ␣-subunit inhibits the sodium pump and increases intracellula ...
... congestive heart failure because the inhibition of Na⫹/K⫹ATPase (sodium pump), which serves as a functional receptor for digitalis, results in an increase in positive inotropy. Binding of digitalis drugs, such as digoxin, to the catalytic ␣-subunit inhibits the sodium pump and increases intracellula ...
SA Node: impulse
... distinct ECG pattern Just as the spread of electrical stimuli through the atria leads to atrial contraction, so the spread of the electrical stimuli through the ventricles leads to ventricular contraction with pumping of blood to the lungs and into the general circulation. In summary, the electrical ...
... distinct ECG pattern Just as the spread of electrical stimuli through the atria leads to atrial contraction, so the spread of the electrical stimuli through the ventricles leads to ventricular contraction with pumping of blood to the lungs and into the general circulation. In summary, the electrical ...
Reendothelialization of Human Heart Valve Neoscaffolds Using
... Background: Heart valve tissue engineering represents a concept for improving the current methods of valvular heart disease therapy. The aim of this study was to develop tissue engineered heart valves combining human umbilical vein endothelial cells (HUVECs) and decellularized human heart valve mat ...
... Background: Heart valve tissue engineering represents a concept for improving the current methods of valvular heart disease therapy. The aim of this study was to develop tissue engineered heart valves combining human umbilical vein endothelial cells (HUVECs) and decellularized human heart valve mat ...
A Glucagon-Like Peptide-1 Analog Reverses the
... corrected by liraglutide (Figure 2A). At this stage, insulininduced phosphorylation of Akt (same as protein kinase B) in both liver and heart were reduced in obese animals (Figure 2B), suggesting insulin resistance. Treatment with liraglutide for 1 week improved all insulin-activated signals examine ...
... corrected by liraglutide (Figure 2A). At this stage, insulininduced phosphorylation of Akt (same as protein kinase B) in both liver and heart were reduced in obese animals (Figure 2B), suggesting insulin resistance. Treatment with liraglutide for 1 week improved all insulin-activated signals examine ...
Assessment of diastolic dysfunction and heart failure with integrated
... Longitudinal systolic dysfunction (Sa <15 cm/s) was less frequent in group 1 (2/23 [8%]) than in group 2 (14/30 [47%]; p <0.05) or in group 3 (8/13 [61%]; p ...
... Longitudinal systolic dysfunction (Sa <15 cm/s) was less frequent in group 1 (2/23 [8%]) than in group 2 (14/30 [47%]; p <0.05) or in group 3 (8/13 [61%]; p ...
motion mode echocardiography on healthy male
... results in the final ventricular volume. High pressure in the ventricle causes blood to backflow and the valves to shut. The contraction of the papillary muscles pulling the chorda tendinae prevents the valves to prolapse into the atrium. From the right ventricle, blood is pumped through the pulmona ...
... results in the final ventricular volume. High pressure in the ventricle causes blood to backflow and the valves to shut. The contraction of the papillary muscles pulling the chorda tendinae prevents the valves to prolapse into the atrium. From the right ventricle, blood is pumped through the pulmona ...
The role of marine omega-3 fatty acids in preventing and treating
... Thirty of these have been subject to meta-analysis which found that EPA+DHA decreased resting heart rate if the baseline rate was > 69/minute (89). Christensen et al. reported a positive correlation between the n-3 fatty acid content of platelets and heart rate variability in patients with type-1 di ...
... Thirty of these have been subject to meta-analysis which found that EPA+DHA decreased resting heart rate if the baseline rate was > 69/minute (89). Christensen et al. reported a positive correlation between the n-3 fatty acid content of platelets and heart rate variability in patients with type-1 di ...
Left Ventricular Assist Device as Permanent Support in Patients with
... Heart failure is a serious condition with an increased risk of premature death risk of permanent illness or damage, or reduced quality of life risk of disability and impaired health-related quality of life The prevalence and incidence of heart failure In a recently published report the prevale ...
... Heart failure is a serious condition with an increased risk of premature death risk of permanent illness or damage, or reduced quality of life risk of disability and impaired health-related quality of life The prevalence and incidence of heart failure In a recently published report the prevale ...
Atrial Fibrillation - Ulster Medical Society
... sinus rhythm is lower than that of amiodarone. Median time to first recurrent episode of AF was 116 days in patients taking dronedarone in comparison to placebo (53 days; p<0.0001).34 Dronedarone should not be used in patients with a history of heart failure, moderate to severe left ventricular syst ...
... sinus rhythm is lower than that of amiodarone. Median time to first recurrent episode of AF was 116 days in patients taking dronedarone in comparison to placebo (53 days; p<0.0001).34 Dronedarone should not be used in patients with a history of heart failure, moderate to severe left ventricular syst ...
Clinical research priorities in adult congenital heart disease
... 13. What criteria should be used to determine need and timing of systemic atrioventricular (i.e. tricuspid) valve regurgitation in a systemic RV? 14. What is the optimal medical therapy for preservation of ventricular systolic and diastolic function in Fontan patients? 15. What are the ideal criteri ...
... 13. What criteria should be used to determine need and timing of systemic atrioventricular (i.e. tricuspid) valve regurgitation in a systemic RV? 14. What is the optimal medical therapy for preservation of ventricular systolic and diastolic function in Fontan patients? 15. What are the ideal criteri ...
Health Care Provider Study Review Guide Handout Page
... be evaluated by checking for a transmitted pulse during the performance of compressions. If no pulse can be felt, the rescuer needs to push harder. Two rescuer CPR can be performed on adults, children and infants. Please refer to the American Heart Association Healthcare Provider Manual for more in ...
... be evaluated by checking for a transmitted pulse during the performance of compressions. If no pulse can be felt, the rescuer needs to push harder. Two rescuer CPR can be performed on adults, children and infants. Please refer to the American Heart Association Healthcare Provider Manual for more in ...
Body Mass Index and Blood Pressure Influences on Left Ventricular
... Gottdiener et al studied a hospital-based population of white American and African American men at 14 VA medical centers nationwide and found a significant association between both obesity and hypertension and cardiac structure and function.20 In this study, obesity was found to be the strongest cli ...
... Gottdiener et al studied a hospital-based population of white American and African American men at 14 VA medical centers nationwide and found a significant association between both obesity and hypertension and cardiac structure and function.20 In this study, obesity was found to be the strongest cli ...
THE CARDIAC IMPULSE AND THE MOTION OF THE HEART
... beat was recorded in the angiocardiogram, the marker being placed in position while the patient was lying flat on the angiocardiogram table. Studies were carried out on 26 patients, who were being investigated before possible cardiac surgery; impulse cardiograms and timed left ventricular angiocardi ...
... beat was recorded in the angiocardiogram, the marker being placed in position while the patient was lying flat on the angiocardiogram table. Studies were carried out on 26 patients, who were being investigated before possible cardiac surgery; impulse cardiograms and timed left ventricular angiocardi ...
Solid Tumour Section Heart: Cardiac Myxoma Atlas of Genetics and Cytogenetics
... Left ventricular myxomas have a higher rate of embolism (64%) than those in other locations, and tend to embolise to the brain more frequently than to other sites in the systemic circulation. Right sided myxomas embolise in approximately 10% of cases, and have the potential to cause fatal pulmonary ...
... Left ventricular myxomas have a higher rate of embolism (64%) than those in other locations, and tend to embolise to the brain more frequently than to other sites in the systemic circulation. Right sided myxomas embolise in approximately 10% of cases, and have the potential to cause fatal pulmonary ...
ISUOG consensus statement: what constitutes a fetal
... mothers with a family history of CHD, maternal diabetes or exposure to teratogenic drugs, and fetuses that have had an increased nuchal translucency thickness measurement. Fetal cardiac abnormalities may occur in association with extracardiac anomalies and therefore a detailed cardiac scan may be in ...
... mothers with a family history of CHD, maternal diabetes or exposure to teratogenic drugs, and fetuses that have had an increased nuchal translucency thickness measurement. Fetal cardiac abnormalities may occur in association with extracardiac anomalies and therefore a detailed cardiac scan may be in ...
Inflow quantification in three-dimensional cardiovascular MR imaging
... coronary imaging, which applies a single large slab over the entire heart in an axial orientation obviates the use of multiple thin slab 3D acquisitions targeted to the right and left coronary arteries (6 – 8). Similarly, single breath-hold (9) or self-navigated 3D cine acquisitions are now becoming ...
... coronary imaging, which applies a single large slab over the entire heart in an axial orientation obviates the use of multiple thin slab 3D acquisitions targeted to the right and left coronary arteries (6 – 8). Similarly, single breath-hold (9) or self-navigated 3D cine acquisitions are now becoming ...
Getting a New Heart
... Your doctor and transplant staff will watch for these signs: 1. Rejection: The risk of rejection never goes away. You will always need anti-rejection drugs. Your doctor may lower the dosage, but you should never skip or stop taking the drugs. A biopsy of the heart is the best way to know if your bo ...
... Your doctor and transplant staff will watch for these signs: 1. Rejection: The risk of rejection never goes away. You will always need anti-rejection drugs. Your doctor may lower the dosage, but you should never skip or stop taking the drugs. A biopsy of the heart is the best way to know if your bo ...
Left Heart Failure With a Normal Ejection Fraction: Identification of
... syndrome, a single pathophysiologic mechanism, diastolic dysfunction, is often ascribed to explain this condition. In view of the clinical heterogeneity of these patients, we hypothesized that subgroups of HFNEF patients may have different underlying pathophysiologic mechanisms. Methods and Results: ...
... syndrome, a single pathophysiologic mechanism, diastolic dysfunction, is often ascribed to explain this condition. In view of the clinical heterogeneity of these patients, we hypothesized that subgroups of HFNEF patients may have different underlying pathophysiologic mechanisms. Methods and Results: ...
Myocardial infarction
Myocardial infarction (MI) or acute myocardial infarction (AMI), commonly known as a heart attack, occurs when blood flow stops to a part of the heart causing damage to the heart muscle. The most common symptom is chest pain or discomfort which may travel into the shoulder, arm, back, neck, or jaw. Often it is in the center or left side of the chest and lasts for more than a few minutes. The discomfort may occasionally feel like heartburn. Other symptoms may include shortness of breath, nausea, feeling faint, a cold sweat, or feeling tired. About 30% of people have atypical symptoms, with women more likely than men to present atypically. Among those over 75 years old, about 5% have had an MI with little or no history of symptoms. An MI may cause heart failure, an irregular heartbeat, or cardiac arrest.Most MIs occur due to coronary artery disease. Risk factors include high blood pressure, smoking, diabetes, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol intake, among others. The mechanism of an MI often involves the rupture of an atherosclerotic plaque, leading to complete blockage of a coronary artery. MIs are less commonly caused by coronary artery spasms, which may be due to cocaine, significant emotional stress, and extreme cold, among others. A number of tests are useful to help with diagnosis, including electrocardiograms (ECGs), blood tests, and coronary angiography. An ECG may confirm an ST elevation MI if ST elevation is present. Commonly used blood tests include troponin and less often creatine kinase MB.Aspirin is an appropriate immediate treatment for a suspected MI. Nitroglycerin or opioids may be used to help with chest pain; however, they do not improve overall outcomes. Supplemental oxygen should be used in those with low oxygen levels or shortness of breath. In ST elevation MIs treatments which attempt to restore blood flow to the heart are typically recommended and include angioplasty, where the arteries are pushed open, or thrombolysis, where the blockage is removed using medications. People who have a non-ST elevation myocardial infarction (NSTEMI) are often managed with the blood thinner heparin, with the additional use angioplasty in those at high risk. In people with blockages of multiple coronary arteries and diabetes, bypass surgery (CABG) may be recommended rather than angioplasty. After an MI, lifestyle modifications, along with long term treatment with aspirin, beta blockers, and statins, are typically recommended.Worldwide, more than 3 million people have ST elevation MIs and 4 million have NSTEMIs each year. STEMIs occur about twice as often in men as women. About one million people have an MI each year in the United States. In the developed world the risk of death in those who have had an STEMI is about 10%. Rates of MI for a given age have decreased globally between 1990 and 2010.