- Journal of Clinical Investigation
... Wiggers (1925) has compared cardiac failure in man to the conditions in animals poisoned by cliloroform or other drugs which "depress" the heart. He believed that "back-pressure," when it occurred was secondary to decreased output due to myocardial weakness. Gibson (1927) believed that both diminish ...
... Wiggers (1925) has compared cardiac failure in man to the conditions in animals poisoned by cliloroform or other drugs which "depress" the heart. He believed that "back-pressure," when it occurred was secondary to decreased output due to myocardial weakness. Gibson (1927) believed that both diminish ...
PROGRAM 31st TURKISH CARDIOLOGY
... Renal denervation: Have the results of recent trials changed our practice? Murat Akçay Learning objective: Based on the results of recent trials, should renal denervation therapy still be preferred in the presence of hypertension? Can it be used in case of conditions other than hypertension, such as ...
... Renal denervation: Have the results of recent trials changed our practice? Murat Akçay Learning objective: Based on the results of recent trials, should renal denervation therapy still be preferred in the presence of hypertension? Can it be used in case of conditions other than hypertension, such as ...
Ranolazine Reduces Remodeling of the Right Ventricle and
... 2013; Toischer et al., 2013) are also implicated in the progression of RV failure in PAH (Voelkel et al., 2012; FreundMichel et al., 2013; Shryock et al., 2013; Toischer et al., 2013). It was recently reported that RAN reduced RV mass, improved RV performance, and increased exercise capacity in 10 p ...
... 2013; Toischer et al., 2013) are also implicated in the progression of RV failure in PAH (Voelkel et al., 2012; FreundMichel et al., 2013; Shryock et al., 2013; Toischer et al., 2013). It was recently reported that RAN reduced RV mass, improved RV performance, and increased exercise capacity in 10 p ...
2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS Guideline for the
... updating, and revising practice guidelines for cardiovascular diseases and procedures, directs and oversees this effort. Writing committees are charged with regularly reviewing and evaluating all available evidence to develop balanced, patientcentric recommendations for clinical practice. Experts in ...
... updating, and revising practice guidelines for cardiovascular diseases and procedures, directs and oversees this effort. Writing committees are charged with regularly reviewing and evaluating all available evidence to develop balanced, patientcentric recommendations for clinical practice. Experts in ...
Full Text
... updating, and revising practice guidelines for cardiovascular diseases and procedures, directs and oversees this effort. Writing committees are charged with regularly reviewing and evaluating all available evidence to develop balanced, patientcentric recommendations for clinical practice. Experts in ...
... updating, and revising practice guidelines for cardiovascular diseases and procedures, directs and oversees this effort. Writing committees are charged with regularly reviewing and evaluating all available evidence to develop balanced, patientcentric recommendations for clinical practice. Experts in ...
Short-Acting Я-Adrenergic Antagonist Esmolol Given at
... fibrillation (VF) in patients with sudden cardiac death. However, return of spontaneous circulation (ROSC) is less common, occurring in ⬇76% of these patients, and survival to hospital discharge is much lower, at 28%.1 The mechanism(s) of myocardial dysfunction after resuscitation is poorly understo ...
... fibrillation (VF) in patients with sudden cardiac death. However, return of spontaneous circulation (ROSC) is less common, occurring in ⬇76% of these patients, and survival to hospital discharge is much lower, at 28%.1 The mechanism(s) of myocardial dysfunction after resuscitation is poorly understo ...
Comprehensive T Wave Morphology Assessment
... how additional calcium or late sodium block, that can decrease torsade risk, affects T wave morphology. Methods and Results-—Twenty-two healthy subjects received a single dose of a pure hERG blocker (dofetilide) and 3 drugs that also block calcium or sodium (quinidine, ranolazine, and verapamil) as ...
... how additional calcium or late sodium block, that can decrease torsade risk, affects T wave morphology. Methods and Results-—Twenty-two healthy subjects received a single dose of a pure hERG blocker (dofetilide) and 3 drugs that also block calcium or sodium (quinidine, ranolazine, and verapamil) as ...
Heart Failure Booklet
... affect how long you live. But with proper medicine in the right doses and careful management, you can live longer and feel better. Many people with heart failure lead normal lives. They can do so because they have learned to take good care of themselves. You too can help control your heart failure b ...
... affect how long you live. But with proper medicine in the right doses and careful management, you can live longer and feel better. Many people with heart failure lead normal lives. They can do so because they have learned to take good care of themselves. You too can help control your heart failure b ...
Cardiac Cycle - Just In Time Medicine
... Each cardiac cycle (heart beat) consists of ventricular diastole (relaxation), followed by ventricular systole (contraction). Atrial systole (atrial contraction) occurs during ventricular diastole. Atrial contraction is initiated by atrial depolarization, which is indicated by the P wave in the ECG. ...
... Each cardiac cycle (heart beat) consists of ventricular diastole (relaxation), followed by ventricular systole (contraction). Atrial systole (atrial contraction) occurs during ventricular diastole. Atrial contraction is initiated by atrial depolarization, which is indicated by the P wave in the ECG. ...
Automated Analysis of the 12-lead ECG in the Emergency
... P = 0.006], whereas an opposite sex composition was observed in non-African-Americans [66 (45.5%) women vs. 79 (54.5%) men; P = 0.006]. Risk factors of coronary heart disease were frequently observed: 263 patients (64%) had hypertension, 131 patients (32%) had diabetes mellitus, and 263 patients (6 ...
... P = 0.006], whereas an opposite sex composition was observed in non-African-Americans [66 (45.5%) women vs. 79 (54.5%) men; P = 0.006]. Risk factors of coronary heart disease were frequently observed: 263 patients (64%) had hypertension, 131 patients (32%) had diabetes mellitus, and 263 patients (6 ...
Physical Examination of the Cardiovascular System
... value, and establishes rapport between patient and physician [2]. First, it is important to be systematic. Second, form a differential diagnosis before you start, so the physical will help rule in/out the possible diagnoses. In addition, try to correlate all information e.g. if the patient has an El ...
... value, and establishes rapport between patient and physician [2]. First, it is important to be systematic. Second, form a differential diagnosis before you start, so the physical will help rule in/out the possible diagnoses. In addition, try to correlate all information e.g. if the patient has an El ...
hERG Blocking Effects
... ▶ Recommended a large value (often cited as >30) ▶ Based on the experimental observation that for compounds ▶ A ratio <30, 95% produce TdP and only 5% do not, ▶ A ratio >30, 15% produce TdP and 85% do not produce. Another safety margin is the time of QT interval lengthening. ▶Concern about the dru ...
... ▶ Recommended a large value (often cited as >30) ▶ Based on the experimental observation that for compounds ▶ A ratio <30, 95% produce TdP and only 5% do not, ▶ A ratio >30, 15% produce TdP and 85% do not produce. Another safety margin is the time of QT interval lengthening. ▶Concern about the dru ...
Vasovagal Syncope (The Common Faint): What
... domains: treatment of the impending reflex (efferent pathway) and prevention of the reflex (afferent pathway) (Alboni, 2010). A list of nonpharmacological interventions for syncope can be seen in Table 1. We will now explore the use of physical manoeuvres and psychological therapies as potential treat ...
... domains: treatment of the impending reflex (efferent pathway) and prevention of the reflex (afferent pathway) (Alboni, 2010). A list of nonpharmacological interventions for syncope can be seen in Table 1. We will now explore the use of physical manoeuvres and psychological therapies as potential treat ...
Folie 1 - PULSION Medical Systems SE: Startseite
... • The variation in stroke volume over the respiratory cycle • Correlates directly with the response of the cardiac ejection to preload increase (volume responsiveness) ...
... • The variation in stroke volume over the respiratory cycle • Correlates directly with the response of the cardiac ejection to preload increase (volume responsiveness) ...
Pulmonary arterial disease with multifocal dissecting
... appeared to have been forced out by the swelling of the outer media, so that the contour of the periphery of the arteries was tuberose rather than regular. Many of the elastic laminae appeared abnormally thick, and some of them showed degeneration of elastin with alternate bands of normal and decrea ...
... appeared to have been forced out by the swelling of the outer media, so that the contour of the periphery of the arteries was tuberose rather than regular. Many of the elastic laminae appeared abnormally thick, and some of them showed degeneration of elastin with alternate bands of normal and decrea ...
Effects of glycyl-glutamine dipeptide supplementation on myocardial
... ischemic damage by preventing cellular memand received anaesthesia, but were not burned. brane leakage [16]. In addition, it can protect Sixty-four burned rats from the B and GG groups myocardial cells by enabling ATP-depleted cells were inflicted with 30% total body surface area to maintain their s ...
... ischemic damage by preventing cellular memand received anaesthesia, but were not burned. brane leakage [16]. In addition, it can protect Sixty-four burned rats from the B and GG groups myocardial cells by enabling ATP-depleted cells were inflicted with 30% total body surface area to maintain their s ...
This gene encodes an alpha-1 subunit of a voltage
... acts on the skeleton to increase bone reabsorption; it acts on the kidney to decrease excretion of calcium. The gene that produces this protein is present in many malignant tissues. (2.2) Granulomatous disorders: High levels of calcitriol may be found in patients with sarcoidosis and other granuloma ...
... acts on the skeleton to increase bone reabsorption; it acts on the kidney to decrease excretion of calcium. The gene that produces this protein is present in many malignant tissues. (2.2) Granulomatous disorders: High levels of calcitriol may be found in patients with sarcoidosis and other granuloma ...
a. equipment failure
... IV. Management/Intervention Column: this column lists specific actions taken by the perfusion staff to prevent each failure mode by pre-emptive management or manage each failure if it does occur. Column V. Risk Priority Number (RPN): Some RPNs are available for common failure modes associated with o ...
... IV. Management/Intervention Column: this column lists specific actions taken by the perfusion staff to prevent each failure mode by pre-emptive management or manage each failure if it does occur. Column V. Risk Priority Number (RPN): Some RPNs are available for common failure modes associated with o ...
PDF
... in the territory of one of its branches. This concept was later redefined by including autonomic symptoms such as a decrease in cardiovascular function less than 20%. This new trigeminocardiac reflex definition is even more inclusive for clinical studies (12). In severe instances, this response can ...
... in the territory of one of its branches. This concept was later redefined by including autonomic symptoms such as a decrease in cardiovascular function less than 20%. This new trigeminocardiac reflex definition is even more inclusive for clinical studies (12). In severe instances, this response can ...
Newly Diagnosed Atrial Fibrillation
... regularity of the cardiac cycle, especially when accompanied by short coupling intervals, and rapid heart rates in atrial fibrillation lead to a reduction in diastolic filling, stroke volume, and cardiac output. In a study of patients who were evaluated while in atrial fibrillation and again during ...
... regularity of the cardiac cycle, especially when accompanied by short coupling intervals, and rapid heart rates in atrial fibrillation lead to a reduction in diastolic filling, stroke volume, and cardiac output. In a study of patients who were evaluated while in atrial fibrillation and again during ...
Falls-associated elevation of troponin level in an older woman with
... In March 2015, a 75-year old woman was taken by ambulance to the emergency department with a head injury and scalp laceration secondary to a nonsyncopal fall. She had normal cognitive function and no history of ischaemic heart disease, diabetes mellitus, or hypertension. She was a non-smoker and non ...
... In March 2015, a 75-year old woman was taken by ambulance to the emergency department with a head injury and scalp laceration secondary to a nonsyncopal fall. She had normal cognitive function and no history of ischaemic heart disease, diabetes mellitus, or hypertension. She was a non-smoker and non ...
Long-term Outcomes in Individuals With Prolonged PR
... the associations of PR interval with the incidence of arrhythmic events and death. Main Outcome Measures Incident atrial fibrillation (AF), pacemaker implantation, and all-cause mortality. Results During follow-up, 481 participants developed AF, 124 required pacemaker implantation, and 1739 died. At ...
... the associations of PR interval with the incidence of arrhythmic events and death. Main Outcome Measures Incident atrial fibrillation (AF), pacemaker implantation, and all-cause mortality. Results During follow-up, 481 participants developed AF, 124 required pacemaker implantation, and 1739 died. At ...
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
... are – for example, how tall we will be or what colour hair we will have. This genetic information is held in our DNA in the cells of our body. The genetic information is produced through a coding system of proteins, represented by letters, that tells all of the cells in our bodies what their functio ...
... are – for example, how tall we will be or what colour hair we will have. This genetic information is held in our DNA in the cells of our body. The genetic information is produced through a coding system of proteins, represented by letters, that tells all of the cells in our bodies what their functio ...
Drug-induced QT prolongation journal article
... it was originally intended, and performs better than Bazett’s formula when used on an intention-to-treat basis, including those patients with tachycardia. Although our search for TdP cases was systematic, it was not exhaustive. It did not include searching databases of spontaneously reported adverse ...
... it was originally intended, and performs better than Bazett’s formula when used on an intention-to-treat basis, including those patients with tachycardia. Although our search for TdP cases was systematic, it was not exhaustive. It did not include searching databases of spontaneously reported adverse ...
hyperbaric oxygen therapy for acute coronary syndrome
... Reviewers' conclusions: For people with ACS, individual small trials suggest the addition of HBOT reduced the risk of Major Adverse Cardiac Events, some dysrrhythmias, and reduced the time to relief from ischaemic pain, but did not reduce mortality. In view of the modest number of patients, methodol ...
... Reviewers' conclusions: For people with ACS, individual small trials suggest the addition of HBOT reduced the risk of Major Adverse Cardiac Events, some dysrrhythmias, and reduced the time to relief from ischaemic pain, but did not reduce mortality. In view of the modest number of patients, methodol ...
Antihypertensive drug
Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34%, of ischaemic heart disease by 21%, and reduce the likelihood of dementia, heart failure, and mortality from cardiovascular disease. There are many classes of antihypertensives, which lower blood pressure by different means. Among the most important and most widely used drugs are thiazide diuretics, calcium channel blockers, ACE inhibitors, angiotensin II receptor antagonists (ARBs), and beta blockers.Which type of medication to use initially for hypertension has been the subject of several large studies and resulting national guidelines. The fundamental goal of treatment should be the prevention of the important endpoints of hypertension, such as heart attack, stroke and heart failure. Patient age, associated clinical conditions and end-organ damage also play a part in determining dosage and type of medication administered. The several classes of antihypertensives differ in side effect profiles, ability to prevent endpoints, and cost. The choice of more expensive agents, where cheaper ones would be equally effective, may have negative impacts on national healthcare budgets. As of 2009, the best available evidence favors the thiazide diuretics as the first-line treatment of choice for high blood pressure when drugs are necessary. Although clinical evidence shows calcium channel blockers and thiazide-type diuretics are preferred first-line treatments for most people (from both efficacy and cost points of view), an ACE inhibitor is recommended by NICE in the UK for those under 55 years old.