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Anril®
Anril®

... reactions are the result of nitroglycerin's activity as a vasodilator. Headache, which may be severe, is the most commonly reported side effect. Headache may be recurrent with each daily dose, especially at higher doses. Transient episodes of lightheadedness, occasionally related to blood pressure c ...
Omega-3 Nutrition-Fish versus Supplements
Omega-3 Nutrition-Fish versus Supplements

... • Dietary intake of fish consistently found to be of benefit for the protection from heart disease and stroke. Higher fish intake was associated with lower incident rates of heart failure,o lower sudden cardiac death, stroke and myocardial infarction. • Heart Foundation recommends all Australians in ...
ATRIAL FIBRILLATION DECISION AID
ATRIAL FIBRILLATION DECISION AID

... Atrial fibrillation is an abnormal heart rhythm during which the upper or filling chambers of the heart beat irregularly. Normally the pacemaker of the heart generates an electrical impulse, which is conducted or carried to the lower or pumping chambers of the heart via the electrical conducting tis ...
Sudden Cardiac Arrest Fact Sheet
Sudden Cardiac Arrest Fact Sheet

... body. The lack of blood to the brain causes the person to lose consciousness quickly. If the person does not receive immediate treatment with defibrillation, brain damage and death can occur. 1 The chances of surviving SCA decrease by 7-10 percent with every minute that passes without a life-saving ...
Resistant Hypertension: A Comprehensive Overview
Resistant Hypertension: A Comprehensive Overview

... ASPIRANT study showed a much smaller 5.4/1 mmHg reduction in ambulatory BP by spironolactone 25mg daily versus placebo, highlighting the importance of placebo control [61]. Hyperkalemia with MRA and other PSDs is more common in patients with diabetes, CKD and/or elevated baseline potassium levels; m ...
of heart failure - Academy of Medicine of Malaysia
of heart failure - Academy of Medicine of Malaysia

... giddiness, his skin is warm and renal function is stable with good urine flow. If the patient fails to respond to the above therapy, further management would depend upon the blood pressure. ...
Women and Cardiovascular Disease
Women and Cardiovascular Disease

... Today, the incidence of hypertension approaches 35%. Of those with hypertension about 75% are aware of their condition but only 50% have their blood pressure under adequate control. Hypertension appears to affect both men and women equally but more men than women are on therapy at any one time. Hype ...
Therapy of Acute Coronary SyndromeTherapy of Acute Coronary
Therapy of Acute Coronary SyndromeTherapy of Acute Coronary

... Long-term therapies • CAD is a chronic condition and patients who have recovered from a STEMI are at high risk for new events and premature death !!! • Most patients with STEMI who die do so after discharge from the index event! ...
Anatomical Survey: Observation of Physical and Functional
Anatomical Survey: Observation of Physical and Functional

... The aforementioned coronary vessels carry blood to and from cardiac tissue and stretch across both anterior and posterior surfaces of the organ. Like the systemic vessels, coronary blood vessels are divided into arteries and veins. Moreover, the vessels of the heart are divided into left and right c ...
Primary FRCA SOE November 2016 Question topics for Monday 7
Primary FRCA SOE November 2016 Question topics for Monday 7

... PHY -051 - buffers | what is a buffer? ...
1. NAME OF THE MEDICINAL PRODUCT Cinfaval 80 mg film-coated tablets
1. NAME OF THE MEDICINAL PRODUCT Cinfaval 80 mg film-coated tablets

... and has much (about 20,000 fold) greater affinity for the AT1 receptor than for the AT2 receptor. Valsartan is not known to bind to or block other hormone receptors or ion channels known to be important in cardiovascular regulation. Valsartan does not inhibit ACE (also known as kininase II) which co ...


... mercury or aneroid sphygmomanometer, with the subject lying after 5 min rest. The subject was instructed to stand up quickly and the BP recorded immediately. The difference in systolic blood pressure (SBP) was calculated ("postural response"). Blood pressure response to sustained handgrip. The subje ...
Welcome to the Cardiac Rehabilitation Department
Welcome to the Cardiac Rehabilitation Department

... the heart, this blocks the blood flow to the area of heart muscle supplied by that artery. This portion of the heart muscle, deprived of oxygen, is then damaged. The amount of permanent damage to the heart muscle depends on a number of factors: the size of the clot; the location of the clot; how lon ...
Who Discovered the Frank-Starling Mechanism?
Who Discovered the Frank-Starling Mechanism?

... right), there was also an increase in diastolic volume that enabled the heart to eject a normal stroke volume (upper recording; Fig. 3, right). In both cases, diastolic fiber length was increased. In a subsequent paper, it was shown that oxygen consumption of the isolated heart is determined by its ...
Cardiac Disease In Cats 2016
Cardiac Disease In Cats 2016

... Hypertrophic Cardiomyopathy (HCM): This is the most common form of heart disease in domestic cats. In humans, HCM has a genetic basis, and several hundred mutations have been associated with the disease. HCM is known to be inherited in several breeds, and genetic mutations (in “Myosin Binding Protei ...
Loss of Epidermal Growth Factor Receptor in Vascular
Loss of Epidermal Growth Factor Receptor in Vascular

... protein 22) promoter. While the reproduction of knockout animals was not impaired, life span was significantly reduced. Systolic blood pressure was not different between the 2 genotypes—neither in tail cuff nor in intravascular measurements— whereas total peripheral vascular resistance, diastolic bl ...
living with heart failure
living with heart failure

... Vasodilators – widen (dilate) blood vessels. When blood vessels widen, blood flows more easily and the heart doesn’t have to work as hard. These medications can be used with ACE inhibitors and ARB’s. Or, they can be used alone if you can’t use the other medications. Some vasodilators, such as nitrat ...
Internal Medicine Board Review: Cardiology Acute Coronary
Internal Medicine Board Review: Cardiology Acute Coronary

... Key Points • Medical therapy for acute, recent myocardial infarction includes B-blocker, aspirin, ACE-inhibitor and statins • This is an uncomplicated (based on the absence of further symptoms and EKG changes) anterior STEMI • Late fibrinolysis is not beneficial for most patients and may be associa ...
Slide 1
Slide 1

... Aortic pressure pulse contours in arteriosclerosis, aortic stenosis, patent ductus arteriosus, and aortic regurgitation ...
cardiovascular physiology and cardiopulmonary interactions
cardiovascular physiology and cardiopulmonary interactions

... Pressure – Left Atrial Pressure / Qp. Where Q is pulmonary blood flow. Heart Rate Normal ranges for HR vary according to age / size of child. Cardiac output is equal to heart rate (HR) X stroke volume (SV). Therefore if the SV is fixed, the CO will increase in direct proportion to the HR. In small i ...
Pericarditis
Pericarditis

... The right side of the heart has less diastolic pressure than left side of the heart and for that reason the cardiac temponade compress right side of the heart because the pressure reach to diastolic pressure of right ventricle or right atrium before reach to left ventricle and so all patients presen ...
heart sounds s2
heart sounds s2

... systemic vascular resistance, it takes some time for the blood flow from the right ventricle to stop • This corresponds to the hangout interval. • On the left side of the heart because impedance is much greater, the hangout interval between the aorta and ...
Guidelines for Perioperative Cardiovascular Evaluation for
Guidelines for Perioperative Cardiovascular Evaluation for

... Very few deaths/ MI during hospitalization, no difference between groups Significant reduction in 6m, 1y, and 2y death and cardiovascular outcomes in the treatment group Mechanism - prevention of catecholamine-induced changes in the coronaries that render patients more susceptible to later complicat ...
Cardiovascular Objectives
Cardiovascular Objectives

... Careful measurement of jugular venous pressure (JVP) is an important and, in some instances, critical portion of the physical exam. The patient initially is placed in the supine position. This position results in engorgement of the jugular veins. The head of the bed is raised gradually until the jug ...
Eplerenone Reduces Mortality 30 Days After Randomization
Eplerenone Reduces Mortality 30 Days After Randomization

... mg after 30 days based on serum potassium levels in the EPHESUS trial, this analysis shows that the lower dose of eplerenone, 25 mg/day, showed significant reductions in mortality and morbidity within 30 days. Aspirin, coronary reperfusion, ACE inhibitors, betablockers, and statins seem to be most e ...
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Antihypertensive drug



Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34%, of ischaemic heart disease by 21%, and reduce the likelihood of dementia, heart failure, and mortality from cardiovascular disease. There are many classes of antihypertensives, which lower blood pressure by different means. Among the most important and most widely used drugs are thiazide diuretics, calcium channel blockers, ACE inhibitors, angiotensin II receptor antagonists (ARBs), and beta blockers.Which type of medication to use initially for hypertension has been the subject of several large studies and resulting national guidelines. The fundamental goal of treatment should be the prevention of the important endpoints of hypertension, such as heart attack, stroke and heart failure. Patient age, associated clinical conditions and end-organ damage also play a part in determining dosage and type of medication administered. The several classes of antihypertensives differ in side effect profiles, ability to prevent endpoints, and cost. The choice of more expensive agents, where cheaper ones would be equally effective, may have negative impacts on national healthcare budgets. As of 2009, the best available evidence favors the thiazide diuretics as the first-line treatment of choice for high blood pressure when drugs are necessary. Although clinical evidence shows calcium channel blockers and thiazide-type diuretics are preferred first-line treatments for most people (from both efficacy and cost points of view), an ACE inhibitor is recommended by NICE in the UK for those under 55 years old.
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