Is our heart a well-designed pump? The heart along animal evolution
... according to their O2 consumption, not to their respective mass.15 Cephalopods (octopus, squids) are highly sophisticated mollusks. They have a closed system of arteries, capillaries and veins lined by endothelial cells, and a double-pressure circulation. A two-chamber heart collecting blood from th ...
... according to their O2 consumption, not to their respective mass.15 Cephalopods (octopus, squids) are highly sophisticated mollusks. They have a closed system of arteries, capillaries and veins lined by endothelial cells, and a double-pressure circulation. A two-chamber heart collecting blood from th ...
Valsartan, Captopril, or Both in Myocardial Infarction
... for cardiovascular events after myocardial infarction. Combining valsartan with captopril increased the rate of adverse events without improving survival. ...
... for cardiovascular events after myocardial infarction. Combining valsartan with captopril increased the rate of adverse events without improving survival. ...
The Abdominojugular Reflux Sign
... vation with inspiration) is seen in 33% of patients with pure constrictive pericarditis (13,14) and, 33% to 100% of patients with right ventricular infarction (9). To the extent that Kussmaul’s sign is due to a similar physiology, abdominojugular reflux may have similar predictive ability. The value ...
... vation with inspiration) is seen in 33% of patients with pure constrictive pericarditis (13,14) and, 33% to 100% of patients with right ventricular infarction (9). To the extent that Kussmaul’s sign is due to a similar physiology, abdominojugular reflux may have similar predictive ability. The value ...
Pulmonary hypertension diagnosed by right heart catheterisation in sickle cell disease
... ABSTRACT: Recent studies have recognised the importance of pulmonary hypertension (PH) in sickle cell disease (SCD). The aim of this study was to determine the prevalence and prognostic impact of PH and its features in patients with SCD. 80 patients with SCD underwent baseline clinical evaluation, l ...
... ABSTRACT: Recent studies have recognised the importance of pulmonary hypertension (PH) in sickle cell disease (SCD). The aim of this study was to determine the prevalence and prognostic impact of PH and its features in patients with SCD. 80 patients with SCD underwent baseline clinical evaluation, l ...
AF Guidelines
... • We recommend administering idarucizimab for emergency reversal of dabigatran's anticoagulant effect in patients with uncontrollable or potentially life-threatening bleeding and/or in patients requiring urgent surgery for which normal hemostasis is necessary (Strong Recommendation, Moderate Quality ...
... • We recommend administering idarucizimab for emergency reversal of dabigatran's anticoagulant effect in patients with uncontrollable or potentially life-threatening bleeding and/or in patients requiring urgent surgery for which normal hemostasis is necessary (Strong Recommendation, Moderate Quality ...
Accuracy and precision of echocardiography versus right heart
... journal homepage: www.elsevier.com/locate/ijcard ...
... journal homepage: www.elsevier.com/locate/ijcard ...
NURS 2410 Unit 8 and 9 plus cardiac
... greater than ventilation (air exchange) in the lung bases. B, When ventilation is inadequate to well-perfused areas of the lungs, the ventilation-perfusion ratio is low or mismatched, resulting in shunting. Blood passing through the pulmonary capillaries gets less oxygen exchange than normal, and hy ...
... greater than ventilation (air exchange) in the lung bases. B, When ventilation is inadequate to well-perfused areas of the lungs, the ventilation-perfusion ratio is low or mismatched, resulting in shunting. Blood passing through the pulmonary capillaries gets less oxygen exchange than normal, and hy ...
Angiotensin II receptor blockade during gestation attenuates
... test the hypothesis that both AngII and TGF-b 1 are involved in cardiac connective tissue formation. We also sought to determine whether blockade of fetal AT1 or AT2 receptors would result in attenuation of cardiac collagen formation. To elucidate the AngII receptor subtype responsible for any obser ...
... test the hypothesis that both AngII and TGF-b 1 are involved in cardiac connective tissue formation. We also sought to determine whether blockade of fetal AT1 or AT2 receptors would result in attenuation of cardiac collagen formation. To elucidate the AngII receptor subtype responsible for any obser ...
Ventricular Tachycardia (VT) and Sudden Cardiac Arrest (SCA)
... influence the electrical substrate involved in VA; are especially useful in setting of hypomagnesemia and hypokalemia ♥ ACE inhibitors, angiotensin receptor blockers and aldosterone blockers can improve the myocardial substrate through reverse remodeling and thus reduce incidence of SCD ♥ Antithromb ...
... influence the electrical substrate involved in VA; are especially useful in setting of hypomagnesemia and hypokalemia ♥ ACE inhibitors, angiotensin receptor blockers and aldosterone blockers can improve the myocardial substrate through reverse remodeling and thus reduce incidence of SCD ♥ Antithromb ...
nt-pro b-type natriuretic peptide (bnp), serum
... NT-proBNP values < 300 pg/mL have a 99% negative predictive value for excluding acute congestive heart failure (CHF). A cutoff of 1,200 pg/mL for patients with an eGFR < 60 yields a diagnostic sensitivity and specificity of 89% and 72% for acute CHF. NT-proBNP values > 450 pg/mL are consistent with ...
... NT-proBNP values < 300 pg/mL have a 99% negative predictive value for excluding acute congestive heart failure (CHF). A cutoff of 1,200 pg/mL for patients with an eGFR < 60 yields a diagnostic sensitivity and specificity of 89% and 72% for acute CHF. NT-proBNP values > 450 pg/mL are consistent with ...
Figure 1: Autonomic function tests between congenitally deaf and
... description by Jervell-Lange in congenitally deaf children and later independently by Romano and Ward in persons with normal hearing. Both variants are characterized by prolongation of QT interval on surface ECG, T wave abnormalities and stress evoked syncope due to ventricular arrhythmias sometimes ...
... description by Jervell-Lange in congenitally deaf children and later independently by Romano and Ward in persons with normal hearing. Both variants are characterized by prolongation of QT interval on surface ECG, T wave abnormalities and stress evoked syncope due to ventricular arrhythmias sometimes ...
applying the finite speed thermodynamics (fst) to the human
... some differential equations which take into account losses through various irreversibilities. These schemes are very sophisticated and sometimes treat the processes three-dimensionally. After many computations (numerical integration), they find „a certain point” in which the machine works with certa ...
... some differential equations which take into account losses through various irreversibilities. These schemes are very sophisticated and sometimes treat the processes three-dimensionally. After many computations (numerical integration), they find „a certain point” in which the machine works with certa ...
My early start to life... - Apollo Bramwell Hospital
... as high blood pressure and tobacco smoke) are present, this risk increases even more. A person’s cholesterol level is also affected by age, sex, heredity and diet. We advise to have a cholesterol check if aged 40 or more, or if you have a strong family history, it is advised to have a check. t)JHI ...
... as high blood pressure and tobacco smoke) are present, this risk increases even more. A person’s cholesterol level is also affected by age, sex, heredity and diet. We advise to have a cholesterol check if aged 40 or more, or if you have a strong family history, it is advised to have a check. t)JHI ...
The Year in Cardiology 2013: heart failure
... Despite success of standard heart failure therapy, morbidity and mortality remain unacceptably high. Adding angiotensin receptor blockers (ARBs) or the renin inhibitor aliskiren to standard angiotensin converting enzyme inhibitors (ACEIs) has not added benefit but increased side effects.19 These stu ...
... Despite success of standard heart failure therapy, morbidity and mortality remain unacceptably high. Adding angiotensin receptor blockers (ARBs) or the renin inhibitor aliskiren to standard angiotensin converting enzyme inhibitors (ACEIs) has not added benefit but increased side effects.19 These stu ...
The Role of Skin and Muscle Resistance Vessels
... the resistance vessels in these tissues could play an important role in the regulation of arterial pressure. The present investigation served two major purposes. The first was to determine if the skin vessels, the muscle vessels, or both participate in baroreceptor-mediated reflexes. This problem ha ...
... the resistance vessels in these tissues could play an important role in the regulation of arterial pressure. The present investigation served two major purposes. The first was to determine if the skin vessels, the muscle vessels, or both participate in baroreceptor-mediated reflexes. This problem ha ...
Slides - Professional Heart Daily
... Low LVEF is a welldemonstrated risk factor for SCD. While low LVEF has been effectively used to select high risk patients for application of therapy to prevent sudden cardiac death, LVEF has limited sensitivity-the majority of SCDs occur in patients with more preserved ...
... Low LVEF is a welldemonstrated risk factor for SCD. While low LVEF has been effectively used to select high risk patients for application of therapy to prevent sudden cardiac death, LVEF has limited sensitivity-the majority of SCDs occur in patients with more preserved ...
Is our heart a well-designed pump? The heart along animal evolution
... cephalopods (octopus) and in all vertebrates. Blood volume is lower (6–8% of body weight), but pressure is higher. The presence of an O2-carrier pigment increases O2 delivery 20–40 times. Haeme pigments are found in practically all classes of living beings. They evolved from enzymes such as cytochro ...
... cephalopods (octopus) and in all vertebrates. Blood volume is lower (6–8% of body weight), but pressure is higher. The presence of an O2-carrier pigment increases O2 delivery 20–40 times. Haeme pigments are found in practically all classes of living beings. They evolved from enzymes such as cytochro ...
Low risk - The Cardiology Report
... 10. Healey JS, Hart RG, Pogue J, et al. Risks and benefits of oral anticoagulation compared with clopidogrel plus aspirin in patients with atrial fibrillation according to stroke risk: the atrial fibrillation clopidogrel trial with irbesartan for prevention of vascular events (ACTIVE-W). Stroke. 200 ...
... 10. Healey JS, Hart RG, Pogue J, et al. Risks and benefits of oral anticoagulation compared with clopidogrel plus aspirin in patients with atrial fibrillation according to stroke risk: the atrial fibrillation clopidogrel trial with irbesartan for prevention of vascular events (ACTIVE-W). Stroke. 200 ...
Effects of colchicine on risk of cardiovascular events among patients
... the non-randomised retrospective design, adds valuable evidence on a potential new role of this old drug in cardiovascular disease—a prospect which has come under scrutiny over the past few years.2 We would like to contribute a few comments and pose some questions. With regard to the reported appare ...
... the non-randomised retrospective design, adds valuable evidence on a potential new role of this old drug in cardiovascular disease—a prospect which has come under scrutiny over the past few years.2 We would like to contribute a few comments and pose some questions. With regard to the reported appare ...
Acute and Fulminant Viral Myocarditis
... 2. New-onset heart failure of 2 weeks to 3 months duration associated with a dilated left ventricle and new ventricular arrhythmias, second- or third-degree heart block, or failure to responds to usual care with 1-2 weeks ...
... 2. New-onset heart failure of 2 weeks to 3 months duration associated with a dilated left ventricle and new ventricular arrhythmias, second- or third-degree heart block, or failure to responds to usual care with 1-2 weeks ...
door to needle time of streptokinase and st segment resolution
... interventional approaches.4 Thrombolytic therapy for acute myocardial infarction reduces fatality and improves clinical outcomes. However, in 60% of patients the treatment does not restore perfusion in the myocardium at risk and such failure indicates a worse prognosis.5 Reperfusion therapy in STEMI ...
... interventional approaches.4 Thrombolytic therapy for acute myocardial infarction reduces fatality and improves clinical outcomes. However, in 60% of patients the treatment does not restore perfusion in the myocardium at risk and such failure indicates a worse prognosis.5 Reperfusion therapy in STEMI ...
infarcts
... • 10% of hospital patients die from this (50,000/yr). • 95% originate in the deep veins of the legs above knee. • Saddle embolus is one that lodges at the common iliac bifurcation. • Most are asymptomatic due to small size. • With greater than 60% of pulmonary arterial system blocked patients develo ...
... • 10% of hospital patients die from this (50,000/yr). • 95% originate in the deep veins of the legs above knee. • Saddle embolus is one that lodges at the common iliac bifurcation. • Most are asymptomatic due to small size. • With greater than 60% of pulmonary arterial system blocked patients develo ...
VitalSim - Laerdal Medical
... Vital signs for manikins and skill trainers The VitalSim Vital Signs Simulator is the heart of Laerdal s VitalSim product line. When connected to VitalSim enabled manikins and skills trainers, VitalSim simulates ECGs, heart sounds, fetal heart tones, breath sounds, bowel sounds, blood pressure and p ...
... Vital signs for manikins and skill trainers The VitalSim Vital Signs Simulator is the heart of Laerdal s VitalSim product line. When connected to VitalSim enabled manikins and skills trainers, VitalSim simulates ECGs, heart sounds, fetal heart tones, breath sounds, bowel sounds, blood pressure and p ...
Antihypertensive drug
Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34%, of ischaemic heart disease by 21%, and reduce the likelihood of dementia, heart failure, and mortality from cardiovascular disease. There are many classes of antihypertensives, which lower blood pressure by different means. Among the most important and most widely used drugs are thiazide diuretics, calcium channel blockers, ACE inhibitors, angiotensin II receptor antagonists (ARBs), and beta blockers.Which type of medication to use initially for hypertension has been the subject of several large studies and resulting national guidelines. The fundamental goal of treatment should be the prevention of the important endpoints of hypertension, such as heart attack, stroke and heart failure. Patient age, associated clinical conditions and end-organ damage also play a part in determining dosage and type of medication administered. The several classes of antihypertensives differ in side effect profiles, ability to prevent endpoints, and cost. The choice of more expensive agents, where cheaper ones would be equally effective, may have negative impacts on national healthcare budgets. As of 2009, the best available evidence favors the thiazide diuretics as the first-line treatment of choice for high blood pressure when drugs are necessary. Although clinical evidence shows calcium channel blockers and thiazide-type diuretics are preferred first-line treatments for most people (from both efficacy and cost points of view), an ACE inhibitor is recommended by NICE in the UK for those under 55 years old.