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The Heart_ Pressure-Propulsion Pump or Organ of Impedance?
The Heart_ Pressure-Propulsion Pump or Organ of Impedance?

... (IABP)-Shock II randomized, open-label multicenter trial found no difference in 30-day mortality (40%) in patients with acute myocardial infarction associated with cardiogenic shock and treated with combined pharmacologic therapy, percutaneous intervention and IABP, or with pharmacologic therapy and ...
Pros and Cons of HGH Therapy in Cardiovascular Disease/ Heart
Pros and Cons of HGH Therapy in Cardiovascular Disease/ Heart

... • HF is a chronic multisystem disease process which is wrought with significant morbidity, mortality and is burdensome on the health care system • Optimal medical management is oftentimes inadequate in fully controlling symptoms • As the end stage of HF results in a catabolic, pro-inflammatory condi ...
failure of the right ventricle
failure of the right ventricle

... was normal in weight and in the thickness of its walls. Practically all the increase in weight of the heart was due to the right ventricle, which weighed nearly as much as the left. The muscle fibres of the right ventricle were greatly hypertrophied ; those of the left ventricle were normal in thick ...
in Patients with Severe Congestive Heart Failure
in Patients with Severe Congestive Heart Failure

... not decreased by milrinone, and therefore, could not be matched to any nitroprusside dose. In the remaining 10 patients matched in this manner, mean arterial pressure was reduced to 70±3 mmHg at the maximum milrinone dose and to aq identical value, 70±4 mmHg with nitroprusside. After matching, the m ...
Document
Document

... pressure during a ventricular cycle Pulse pressure – the difference between systolic and diastolic pressure Mean arterial pressure (MAP) – pressure that propels the blood to the tissues MAP = diastolic pressure + 1/3 pulse pressure ...
Noncardiothoracic nonobstetric surgery in mild-to-moderate pulmonary hypertension
Noncardiothoracic nonobstetric surgery in mild-to-moderate pulmonary hypertension

... maintaining appropriate systemic perfusion pressure for adequate coronary perfusion and enhancing myocardial contractility [25]. There have been very few studies of well-characterised patients with PH undergoing noncardiothoracic nonobstetric surgery. Perioperative mortality and complication rates h ...
Right Heart Evaluation Right Heart Evaluation
Right Heart Evaluation Right Heart Evaluation

... • The parameters to be performed and reported should include: 1. RV size 2. RA size 3. RV systolic function (at least one of the following: FAC, S’, and TAPSE; with or without RV RIMP) 4. SPAP with estimate of RA pressure on the basis of IVC size and collapse • In many conditions, additional measure ...
Circulatory System and Blood
Circulatory System and Blood

... a) What is the blood type of Student 2? (1 mark) The student 2 has blood type A, because antigen A agglutinates with antibody A. b) Which student(s) may receive a transfusion of A blood (A-type blood that is Rh+) with no ill effect? (1 mark) Student 4 can receive blood A with Rh+. The data shows ...
Eur Heart J Cardiovasc Imaging-2014-Galderisi-ehjci-jeu022
Eur Heart J Cardiovasc Imaging-2014-Galderisi-ehjci-jeu022

... the mitral annulus. This parameter correlates with the rate of myocardial relaxation and is relatively independent on pressure flow gradients.6 In addition to be widely feasible and available, the E/e′ ratio predicts the outcome in the settings of acute myocardial infarction,7 heart failure,8 arteri ...
CARDIAC MURMUR What does it mean?
CARDIAC MURMUR What does it mean?

... below the aortic valve n  ...
Variation and association of body mass index with myocardial
Variation and association of body mass index with myocardial

... thickness], contractility, and heart rate. Other, less important factors include external work performed by the heart, the energy necessary for activation, and the basal metabolism of the myocardium.[1,2,11,12] Thus the study shows that there is hemodynamic stress to the heart in study subjects. Thi ...
Chapter 11 ppt - Fillmore Central Schools
Chapter 11 ppt - Fillmore Central Schools

... Congestive Heart Failure (CHF) • Decline in pumping efficiency of heart • Inadequate circulation • Progressive, also coronary atherosclerosis, high blood pressure and history of multiple Myocardial Infarctions • Left side fails = pulmonary congestion and suffocation • Right side fails = peripheral ...
Powerpoint
Powerpoint

... Congestive Heart Failure (CHF) • Decline in pumping efficiency of heart • Inadequate circulation • Progressive, also coronary atherosclerosis, high blood pressure and history of multiple Myocardial Infarctions • Left side fails = pulmonary congestion and suffocation • Right side fails = peripheral ...
Heart Failure with Preserved Ejection Fraction
Heart Failure with Preserved Ejection Fraction

... The results of the above mentioned trials with ACE-inhibitors and ARBs seem counterintuitive. In HFREF patients, ACE-inhibitors and ARBs have been shown to promote reverse remodelling and reduce myocardial fibrosis. The extent of myocardial fibrosis in HFPEF is less than in HFREF [42], a finding t ...
The Cardiovascular System
The Cardiovascular System

... Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings ...
Cardiac Hypertrophy Is Associated With Decreased eNOS
Cardiac Hypertrophy Is Associated With Decreased eNOS

... cardiovascular system and thus, counteract the growthpromoting action of AT1 receptors.1–3 However, the pathophysiologic relevance of AT2 receptors for cardiac remodeling has not yet been firmly established. Recently, transgenic and gene-targeted mouse models with overexpression or deficiency in ang ...
Brain Natriuretic Peptide (BNP) Level
Brain Natriuretic Peptide (BNP) Level

... B-type natriuretic peptide (BNP) is a cardiac neurohormone produced mainly in the left ventricle. It is secreted in response to ventricular volume expansion and pressure overload, factors often found in congestive heart failure (CHF). Used in conjunction with other clinical information, rapid measur ...
Fontan failure associated with a restrictive systemic
Fontan failure associated with a restrictive systemic

... diastolic pressure, end-systolic volume, and stroke volume. Chronic volume deprivation, however, is a rare and largely unknown phenomenon. There has been some interest in the effects of chronic volume deprivation in patients with mitral stenosis.3,4 These studies demonstrate that a chronic deprivati ...
Slide 11.2a - domenicoscience
Slide 11.2a - domenicoscience

... Congestive Heart Failure (CHF) • Decline in pumping efficiency of heart • Inadequate circulation • Progressive, also coronary atherosclerosis, high blood pressure and history of multiple Myocardial Infarctions • Left side fails = pulmonary congestion and suffocation • Right side fails = peripheral ...
Staged Surgical Treatment in an Infant with Huge Aortopulmonary
Staged Surgical Treatment in an Infant with Huge Aortopulmonary

... tachypnea, dyspnea, cardiomegaly, and systemic venous congestion. Growth retardation and pulmonary hypertension may be associated with APW. In case of a delayed diagnosis, adult patients and even infants may be considered as inoperable because of the development of the pulmonary vascular disease and ...
European multicentre validation study of the accuracy of E/e ratio in
European multicentre validation study of the accuracy of E/e ratio in

... the mitral annulus. This parameter correlates with the rate of myocardial relaxation and is relatively independent on pressure flow gradients.6 In addition to be widely feasible and available, the E/e′ ratio predicts the outcome in the settings of acute myocardial infarction,7 heart failure,8 arteri ...
Cardiovascular Disease in OB - UC San Diego Health Sciences
Cardiovascular Disease in OB - UC San Diego Health Sciences

... • How much can the patient do before she gets symptoms? • Let’s hear it for the history! ...
Cardiovascular disease in obstetrics
Cardiovascular disease in obstetrics

... • How much can the patient do before she gets symptoms? • Let’s hear it for the history! ...
The Framingham Heart Study and the epidemiology of
The Framingham Heart Study and the epidemiology of

... In 1947, as legislators were drafting the National Heart Act, the US Public Health Service delegated a young officer and physician, Gilcin Meadors, to compile a proposal for the future epidemiological study (figure 1). Although the study initially focused on ischaemic heart disease, Meadors set the ton ...
File
File

... Congestive Heart Failure (CHF) • Decline in pumping efficiency of heart • Inadequate circulation • Progressive, also coronary atherosclerosis, high blood pressure and history of multiple Myocardial Infarctions • Left side fails = pulmonary congestion and suffocation • Right side fails = peripheral ...
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Antihypertensive drug



Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34%, of ischaemic heart disease by 21%, and reduce the likelihood of dementia, heart failure, and mortality from cardiovascular disease. There are many classes of antihypertensives, which lower blood pressure by different means. Among the most important and most widely used drugs are thiazide diuretics, calcium channel blockers, ACE inhibitors, angiotensin II receptor antagonists (ARBs), and beta blockers.Which type of medication to use initially for hypertension has been the subject of several large studies and resulting national guidelines. The fundamental goal of treatment should be the prevention of the important endpoints of hypertension, such as heart attack, stroke and heart failure. Patient age, associated clinical conditions and end-organ damage also play a part in determining dosage and type of medication administered. The several classes of antihypertensives differ in side effect profiles, ability to prevent endpoints, and cost. The choice of more expensive agents, where cheaper ones would be equally effective, may have negative impacts on national healthcare budgets. As of 2009, the best available evidence favors the thiazide diuretics as the first-line treatment of choice for high blood pressure when drugs are necessary. Although clinical evidence shows calcium channel blockers and thiazide-type diuretics are preferred first-line treatments for most people (from both efficacy and cost points of view), an ACE inhibitor is recommended by NICE in the UK for those under 55 years old.
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