Predictors of Appropriate Implantable Cardioverter
... tricular function as independent predictors of appropriate ICD therapy, whereas the extent of coronary disease was not predictive. Impaired renal function was also associated with a higher rate of appropriate ICD therapies, just reaching statistical significance in multivariate analysis. Among patie ...
... tricular function as independent predictors of appropriate ICD therapy, whereas the extent of coronary disease was not predictive. Impaired renal function was also associated with a higher rate of appropriate ICD therapies, just reaching statistical significance in multivariate analysis. Among patie ...
role of lipistat in protection against isoproterenol induced myocardial
... cardioprotective action of Lipistat, although microscopic histopathological findings were not statistically significant. From the gross histopathological data of this study it appears that 350 mg/kg might be the most effective dose. The mechanism of such a beneficial action might be through preserva ...
... cardioprotective action of Lipistat, although microscopic histopathological findings were not statistically significant. From the gross histopathological data of this study it appears that 350 mg/kg might be the most effective dose. The mechanism of such a beneficial action might be through preserva ...
Heart Failure with a Preserved Ejection Fraction
... signs and symptoms of heart failure may occur in patients in whom the ejection fraction of the left ventricle (LV) is within normal limits. Although originally studied in patients with genuine hypertrophic cardiomyopathy, heart failure with “preserved” LV ejection fraction (HFPEF) has now been recog ...
... signs and symptoms of heart failure may occur in patients in whom the ejection fraction of the left ventricle (LV) is within normal limits. Although originally studied in patients with genuine hypertrophic cardiomyopathy, heart failure with “preserved” LV ejection fraction (HFPEF) has now been recog ...
Medical Milestones in Myocardial Infarction
... • 58 million Americans have one or more types of cardiovascular disease • Approximately 1 million Americans will have a new/recurrent myocardial infarction this year • Coronary heart disease is the single largest cause of death in the United States • Estimated direct/indirect cost: • Coronary heart ...
... • 58 million Americans have one or more types of cardiovascular disease • Approximately 1 million Americans will have a new/recurrent myocardial infarction this year • Coronary heart disease is the single largest cause of death in the United States • Estimated direct/indirect cost: • Coronary heart ...
Braunwald`s Heart Disease Review and Assessment
... broaden our knowledge, changes in practice, treatment and drug therapy may become necessary or appropriate. Readers are advised to check the most current information provided (i) on procedures featured or (ii) by the manufacturer of each product to be administered, to verify the recommended dose or ...
... broaden our knowledge, changes in practice, treatment and drug therapy may become necessary or appropriate. Readers are advised to check the most current information provided (i) on procedures featured or (ii) by the manufacturer of each product to be administered, to verify the recommended dose or ...
Effects of Aging on the Cardiovascular System
... elastic arteries dilate, something that is evident to the naked eye, and that is well seen in arterial radiographic studies. These readily visible changes arise from microscopic changes in the wall structure of the centrally located, large elastic arteries.1,2 The arterial wall is composed of three ...
... elastic arteries dilate, something that is evident to the naked eye, and that is well seen in arterial radiographic studies. These readily visible changes arise from microscopic changes in the wall structure of the centrally located, large elastic arteries.1,2 The arterial wall is composed of three ...
The Relationship Between the Right€Ventricle and its Load
... elastance and arterial elastance E es /E a. The singlebeat analysis gives Ees/E a ¼ Pisovol /P es 1 (with Pes being end-systolic pressure); as a further simplification, P es is often set equal to mPAP. The slope of the P-V relation at end-diastole, called end-diastolic elastance (E ed ) (area C in ...
... elastance and arterial elastance E es /E a. The singlebeat analysis gives Ees/E a ¼ Pisovol /P es 1 (with Pes being end-systolic pressure); as a further simplification, P es is often set equal to mPAP. The slope of the P-V relation at end-diastole, called end-diastolic elastance (E ed ) (area C in ...
NON-VALVULAR ATRIAL FIBRILLATION AND STROKE
... This is described as 'grave' in the Framingham Study 1; the mortality is doubled and within this figure, the cardiovascular mortality is doubled 1. As regards morbidity, AF was associated with a six-fold increased risk of strokes, which were large with disabling residual deficits. Stroke appeared to ...
... This is described as 'grave' in the Framingham Study 1; the mortality is doubled and within this figure, the cardiovascular mortality is doubled 1. As regards morbidity, AF was associated with a six-fold increased risk of strokes, which were large with disabling residual deficits. Stroke appeared to ...
Role of Cardiac, Pulmonary, and Carotid
... decreases in hind-limb and renal blood flows during vagal cold block were not significantly different from those with only the heart in situ. In all eight dogs with only the lungs in situ, vagal block also was performed with the tidal volume set at 10 and at 40 ml/kg—that is, at half and at twice th ...
... decreases in hind-limb and renal blood flows during vagal cold block were not significantly different from those with only the heart in situ. In all eight dogs with only the lungs in situ, vagal block also was performed with the tidal volume set at 10 and at 40 ml/kg—that is, at half and at twice th ...
Data Supplement
... in both groups by abdominal aortic banding as we described previously1,3. Briefly, rats were anesthetized, the abdominal aorta was exposed under sterile conditions through a midline abdominal incision, and a blunted 25-gauge needle (outside diameter, 0.5 mm) placed between the right and left renal a ...
... in both groups by abdominal aortic banding as we described previously1,3. Briefly, rats were anesthetized, the abdominal aorta was exposed under sterile conditions through a midline abdominal incision, and a blunted 25-gauge needle (outside diameter, 0.5 mm) placed between the right and left renal a ...
Losartan Mylan film-coated tablet ENG SmPC
... during concomitant administration of lithium with ACE inhibitors. Very rare cases have also been reported with angiotensin II receptor antagonists. Co-administration of lithium and losartan should be undertaken with caution. If this combination proves essential, serum lithium level monitoring is rec ...
... during concomitant administration of lithium with ACE inhibitors. Very rare cases have also been reported with angiotensin II receptor antagonists. Co-administration of lithium and losartan should be undertaken with caution. If this combination proves essential, serum lithium level monitoring is rec ...
Role of ATP-binding cassette transporters in drug distribution to the
... and decreased the survival rate compared with doxorubicin alone [17]. Other studies in rodents demonstrated that two other multidrug-resistancereversing agents, cyclosporine A or its analog, PSC 833, could also increase doxorubicin concentrations [18,19]. This latter finding correlated with a greate ...
... and decreased the survival rate compared with doxorubicin alone [17]. Other studies in rodents demonstrated that two other multidrug-resistancereversing agents, cyclosporine A or its analog, PSC 833, could also increase doxorubicin concentrations [18,19]. This latter finding correlated with a greate ...
Aldo-HF trial - Dr Richard Bogle
... HF with preserved EF. The change in E/e' (ie, the relation of peak early transmitral ventricular filling velocity to early diastolic tissue Doppler velocity as an echocardiographic estimate of filling pressure) at 12 months and the change in maximum exercise capacity (peak V̇O2 on cardiopulmonary ex ...
... HF with preserved EF. The change in E/e' (ie, the relation of peak early transmitral ventricular filling velocity to early diastolic tissue Doppler velocity as an echocardiographic estimate of filling pressure) at 12 months and the change in maximum exercise capacity (peak V̇O2 on cardiopulmonary ex ...
Forearm Blood Flow In Individuals With CHF And Age
... the widespread prescription of vasodilators (such as ACE inhibitors, angiotensin receptor-blockers, ...
... the widespread prescription of vasodilators (such as ACE inhibitors, angiotensin receptor-blockers, ...
Safety and efficacy of exercise training in
... sudden cardiac death due to exercise is unknown, but probably quite low for mild to moderate exercise. However, it is at least a common clinical experience that heavy exercise can be dangerous in PH. In an animal model, exercise training significantly reduced the survival of those rats that received ...
... sudden cardiac death due to exercise is unknown, but probably quite low for mild to moderate exercise. However, it is at least a common clinical experience that heavy exercise can be dangerous in PH. In an animal model, exercise training significantly reduced the survival of those rats that received ...
Cardiac Activities
... Dissect the double pithed frog as described below: 1. Place the frog on its dorsal surface in the dissecting pan. 2. Pin the upper and lower extremities of the frog securely to the rubber mat in the pan. 3. Cut the skin from the pelvic region to the throat of the frog. 4. Make a mid ventral incision ...
... Dissect the double pithed frog as described below: 1. Place the frog on its dorsal surface in the dissecting pan. 2. Pin the upper and lower extremities of the frog securely to the rubber mat in the pan. 3. Cut the skin from the pelvic region to the throat of the frog. 4. Make a mid ventral incision ...
Palliative Care for Advanced Heart Failure: An Overview
... both common and on the rise1, and heart failure is a final common pathway of various cardiac conditions leading to death. In fact, advanced heart failure (AHF) was described as more ‘malignant’ than cancer because of its poor one-year survival rate and its prognosis worse than for most common forms ...
... both common and on the rise1, and heart failure is a final common pathway of various cardiac conditions leading to death. In fact, advanced heart failure (AHF) was described as more ‘malignant’ than cancer because of its poor one-year survival rate and its prognosis worse than for most common forms ...
Implantable Cardioverter Defibrillator
... Waiting Period: An important issue in the timing of ICD insertion for primary prevention, which has garnered increasing attention recently, is the “waiting period” prior to ICD implantation for certain indications. This has resulted from guidelines and payment policies, predominantly on the part of ...
... Waiting Period: An important issue in the timing of ICD insertion for primary prevention, which has garnered increasing attention recently, is the “waiting period” prior to ICD implantation for certain indications. This has resulted from guidelines and payment policies, predominantly on the part of ...
Screening for Lipid Disorders in Adults
... Would these patients benefit from treatment for elevated triglyceride levels? Older evidence on this question is inconclusive,6 as are recent clinical trials. Because statins, like some other classes of lipid-lowering drugs, reduce triglyceride levels as well as LDL-C levels, they cannot help determ ...
... Would these patients benefit from treatment for elevated triglyceride levels? Older evidence on this question is inconclusive,6 as are recent clinical trials. Because statins, like some other classes of lipid-lowering drugs, reduce triglyceride levels as well as LDL-C levels, they cannot help determ ...
Management of Patients With Atrial Fibrillation
... deterioration of mechanical function. AF is the most common Clinical Eval. ...
... deterioration of mechanical function. AF is the most common Clinical Eval. ...
management of patients with repaired congenital heart disease
... PBF5. The extent of right-to-left shunting depends mainly on the magnitude of the RV outflow tract obstruction as well as the SVR5. Surgical repair Treatment of TOF has shifted from palliation with subsequent repair to early total repair6. Symptomatic children are now repaired at any age, and electi ...
... PBF5. The extent of right-to-left shunting depends mainly on the magnitude of the RV outflow tract obstruction as well as the SVR5. Surgical repair Treatment of TOF has shifted from palliation with subsequent repair to early total repair6. Symptomatic children are now repaired at any age, and electi ...
Cardioprotective Effects of Acute Normovolemic
... Study objectives: We hypothesized that lowering blood viscosity with acute normovolemic hemodilution (ANH) would confer additional cardioprotection in patients undergoing coronary artery bypass surgery (CABG) with aortic cross-clamping. Design: In a prospective, randomized controlled trial, we studi ...
... Study objectives: We hypothesized that lowering blood viscosity with acute normovolemic hemodilution (ANH) would confer additional cardioprotection in patients undergoing coronary artery bypass surgery (CABG) with aortic cross-clamping. Design: In a prospective, randomized controlled trial, we studi ...
Relation of plasma matrix metalloproteinase
... the early and late post-MI period.[3,4] Among MMP types, MMP-8 and MMP-9 exhibit significantly higher levels in the early post-MI period. Increased early levels of these two MMPs have been associated with early remodeling and even infarct rupture.[5,6] However, these MMPs may have a biphasic plasma ...
... the early and late post-MI period.[3,4] Among MMP types, MMP-8 and MMP-9 exhibit significantly higher levels in the early post-MI period. Increased early levels of these two MMPs have been associated with early remodeling and even infarct rupture.[5,6] However, these MMPs may have a biphasic plasma ...
投影片 1
... Do not administer AV nodal blocking agents such as adenosine, calcium channel blockers, digoxin, ß-blockers . (can cause a paradoxical increase in the ventricular response to the rapid atrial impulses of atrial fibril ...
... Do not administer AV nodal blocking agents such as adenosine, calcium channel blockers, digoxin, ß-blockers . (can cause a paradoxical increase in the ventricular response to the rapid atrial impulses of atrial fibril ...
Antihypertensive drug
Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34%, of ischaemic heart disease by 21%, and reduce the likelihood of dementia, heart failure, and mortality from cardiovascular disease. There are many classes of antihypertensives, which lower blood pressure by different means. Among the most important and most widely used drugs are thiazide diuretics, calcium channel blockers, ACE inhibitors, angiotensin II receptor antagonists (ARBs), and beta blockers.Which type of medication to use initially for hypertension has been the subject of several large studies and resulting national guidelines. The fundamental goal of treatment should be the prevention of the important endpoints of hypertension, such as heart attack, stroke and heart failure. Patient age, associated clinical conditions and end-organ damage also play a part in determining dosage and type of medication administered. The several classes of antihypertensives differ in side effect profiles, ability to prevent endpoints, and cost. The choice of more expensive agents, where cheaper ones would be equally effective, may have negative impacts on national healthcare budgets. As of 2009, the best available evidence favors the thiazide diuretics as the first-line treatment of choice for high blood pressure when drugs are necessary. Although clinical evidence shows calcium channel blockers and thiazide-type diuretics are preferred first-line treatments for most people (from both efficacy and cost points of view), an ACE inhibitor is recommended by NICE in the UK for those under 55 years old.