Arterial stiffness: insights from Framingham and Iceland
... aortic diameter, which may temporarily obscure the effect of wall stiffness on Zc and PP. On the basis of hemodynamics, aortic lumen enlargement seems to approach a limit after midlife when PP and CFPWV increase in parallel, suggesting an ongoing increase in aortic wall stiffness with minimal additi ...
... aortic diameter, which may temporarily obscure the effect of wall stiffness on Zc and PP. On the basis of hemodynamics, aortic lumen enlargement seems to approach a limit after midlife when PP and CFPWV increase in parallel, suggesting an ongoing increase in aortic wall stiffness with minimal additi ...
Aortic-Valve Stenosis — From Patients at Risk to Severe Valve
... Panel A shows a long-axis, two-dimensional echocardiographic view of a normal aortic valve, in which the thin valve leaflets are seen in the open position, parallel to the walls of the aorta, in mid-systole. The left ventricle is normal in size and wall thickness, the mitral valve is closed, and the ...
... Panel A shows a long-axis, two-dimensional echocardiographic view of a normal aortic valve, in which the thin valve leaflets are seen in the open position, parallel to the walls of the aorta, in mid-systole. The left ventricle is normal in size and wall thickness, the mitral valve is closed, and the ...
Aortic-Valve Stenosis - American College of Cardiology
... Panel A shows a long-axis, two-dimensional echocardiographic view of a normal aortic valve, in which the thin valve leaflets are seen in the open position, parallel to the walls of the aorta, in mid-systole. The left ventricle is normal in size and wall thickness, the mitral valve is closed, and the ...
... Panel A shows a long-axis, two-dimensional echocardiographic view of a normal aortic valve, in which the thin valve leaflets are seen in the open position, parallel to the walls of the aorta, in mid-systole. The left ventricle is normal in size and wall thickness, the mitral valve is closed, and the ...
Transcatheter aortic and mitral valve interventions
... The overwhelming majority of AV interventions is performed for degenerative disease, notably calcified aortic stenosis (AS). For this entity, surgical AV replacement (AVR) is currently the treatment of choice, with well-defined indications [6] and low perioperative morbidity and mortality [7] . Even ...
... The overwhelming majority of AV interventions is performed for degenerative disease, notably calcified aortic stenosis (AS). For this entity, surgical AV replacement (AVR) is currently the treatment of choice, with well-defined indications [6] and low perioperative morbidity and mortality [7] . Even ...
Flow Characteristics of the Medtronic CoreValve: Difficulties
... less-invasive alternative for patients with severe symptomatic aortic stenosis who are at high-risk for surgical AVR2,3. Survival after TAVI is higher compared to medical therapy alone4, and is comparable with surgical AVR at 1-year5. The need for accurate follow-up assessment of TAVI devices is the ...
... less-invasive alternative for patients with severe symptomatic aortic stenosis who are at high-risk for surgical AVR2,3. Survival after TAVI is higher compared to medical therapy alone4, and is comparable with surgical AVR at 1-year5. The need for accurate follow-up assessment of TAVI devices is the ...
Preparatory Balloon Aortic Valvuloplasty During Transcatheter Aortic
... the myocardial supply/demand ratio showed that the frequency of exceeding the cutoff values that have previously been associated with increased mortality was decreased in the balloon-sizing group (11,14,15). Reduction of PAR and its associated hemodynamic burden could play an important ...
... the myocardial supply/demand ratio showed that the frequency of exceeding the cutoff values that have previously been associated with increased mortality was decreased in the balloon-sizing group (11,14,15). Reduction of PAR and its associated hemodynamic burden could play an important ...
MCQs 3.25MB 2017-03
... d. is curative by removing the inciting eye e. can occur following cataract surgery ...
... d. is curative by removing the inciting eye e. can occur following cataract surgery ...
Auscultation of the Heart
... a systolic ejection murmur as the volume of ejected blood from the left ventricle is increased. Pansystolic murmurs result from retrograde flow from a high-pressure chamber to a low-pressure chamber. Common conditions associated with pansystolic murmurs include ventricular septal defect, mitral insu ...
... a systolic ejection murmur as the volume of ejected blood from the left ventricle is increased. Pansystolic murmurs result from retrograde flow from a high-pressure chamber to a low-pressure chamber. Common conditions associated with pansystolic murmurs include ventricular septal defect, mitral insu ...
Clinical significance of cardiac murmurs: Get the sound and rhythm
... valve area, radiating dorsally with an intensity varying between 1/6 and 5/6. The backflow of blood into the left atrium results in an increased atrial filling with more blood flow during early ventricular filling often producing a louder third heart sound. Increased atrial pressures impede pulmonar ...
... valve area, radiating dorsally with an intensity varying between 1/6 and 5/6. The backflow of blood into the left atrium results in an increased atrial filling with more blood flow during early ventricular filling often producing a louder third heart sound. Increased atrial pressures impede pulmonar ...
Congenital Aneurysms of the Aortic Sinuses with
... of all three sinuses; they state that the increased pressure in the aorta proximal to the coarctation magnifies the congenital weakness of the elastic tissue at the base of the aorta and makes early aneurysm formation and rupture more likely. In 1955, Steinberg and Geller” reported three cases of ge ...
... of all three sinuses; they state that the increased pressure in the aorta proximal to the coarctation magnifies the congenital weakness of the elastic tissue at the base of the aorta and makes early aneurysm formation and rupture more likely. In 1955, Steinberg and Geller” reported three cases of ge ...
Percentage of Left Ventricular
... between the left ventricular stroke work loss and the aortic valve area in cm2 and cm2/m2 was - 0.79 and - 0.80, respectively (fig. 2). With five exceptions (cases 5, 6, 9, 10, and 47), patients who had aortic valve areas of 1.0 cm2 or less had greater than 30% left ventricular stroke work loss, and ...
... between the left ventricular stroke work loss and the aortic valve area in cm2 and cm2/m2 was - 0.79 and - 0.80, respectively (fig. 2). With five exceptions (cases 5, 6, 9, 10, and 47), patients who had aortic valve areas of 1.0 cm2 or less had greater than 30% left ventricular stroke work loss, and ...
Physical Examination of the Cardiovascular System
... not normally found in adults, except for pregnant women whose blood viscosity and velocity resemble children’s; when significant murmurs are found in nonpregnant adults, echocardiography is prudent [4]. An important issue that arises during the physical examination is how to distinguish physiologica ...
... not normally found in adults, except for pregnant women whose blood viscosity and velocity resemble children’s; when significant murmurs are found in nonpregnant adults, echocardiography is prudent [4]. An important issue that arises during the physical examination is how to distinguish physiologica ...
Congenital thoracic arterial anomalies in adults
... Pulmonary artery stenosis Pulmonary artery stenosis in adults is rare. Although it can be isolated, pulmonary artery stenosis is frequently associated with other congenital cardiac malformations. This abnormality is also associated with Williams syndrome, Ehlers-Danlos syndrome, Down syndrome, and i ...
... Pulmonary artery stenosis Pulmonary artery stenosis in adults is rare. Although it can be isolated, pulmonary artery stenosis is frequently associated with other congenital cardiac malformations. This abnormality is also associated with Williams syndrome, Ehlers-Danlos syndrome, Down syndrome, and i ...
Structural Heart Disease - Circulation: Cardiovascular Interventions
... Background—Aortic regurgitation (AR) after transcatheter aortic valve implantation (TAVI) has been associated with poor outcomes, but little is known about how it evolves over time. We evaluated left ventricular (LV) function, remodeling, and the occurrence and evolution of AR after TAVI by using ca ...
... Background—Aortic regurgitation (AR) after transcatheter aortic valve implantation (TAVI) has been associated with poor outcomes, but little is known about how it evolves over time. We evaluated left ventricular (LV) function, remodeling, and the occurrence and evolution of AR after TAVI by using ca ...
STG- TAVI seminar-DR. SANDEEP MOHANAN
... • Concomitant CAD : SVD/ TVD • Surgical Risk : STS-PROM at 30days - Low : <4% - Intermediate: 4-8% - High: >8-15% - Prohibitive : >15%, >50% all-cause mortality risk at 1 year , porcelain aorta, prior radiation, post bypass surgery with adherent grafts to chest wall, ≥3 major organ dysfunction ...
... • Concomitant CAD : SVD/ TVD • Surgical Risk : STS-PROM at 30days - Low : <4% - Intermediate: 4-8% - High: >8-15% - Prohibitive : >15%, >50% all-cause mortality risk at 1 year , porcelain aorta, prior radiation, post bypass surgery with adherent grafts to chest wall, ≥3 major organ dysfunction ...
Current Status of Transcatheter Aortic Valve Replacement
... Surgical aortic valve replacement (SAVR) has long been the mainstay of therapy for severe aortic stenosis. However, transcatheter aortic valve replacement (TAVR) is now generally accepted as the new standard of care for patients with symptomatic aortic stenosis who are not candidates for open surger ...
... Surgical aortic valve replacement (SAVR) has long been the mainstay of therapy for severe aortic stenosis. However, transcatheter aortic valve replacement (TAVR) is now generally accepted as the new standard of care for patients with symptomatic aortic stenosis who are not candidates for open surger ...
STATE OF ART ON TRANSCATHETER AORTIC VALVE
... demonstrated that the cerebral embolism can occur in any time during the TAVI procedure, the phase at greatest risk is undoubtedly that of the implant of the prosthetic valve, which would lead to identify emboli of elements of calcium of the native valve the leading cause of cerebral embolism associ ...
... demonstrated that the cerebral embolism can occur in any time during the TAVI procedure, the phase at greatest risk is undoubtedly that of the implant of the prosthetic valve, which would lead to identify emboli of elements of calcium of the native valve the leading cause of cerebral embolism associ ...
Aortic stiffness and valvular calcifications in patients with end
... aorta and other large vessels was reduced as compared to 90 healthy subjects. Blacher et al. [15] showed that in patients on hemodialysis aortic stiffness increases the risk of total and cardiovascular mortality. It results in the rise of arterial blood pressure, which is the direct cause for increa ...
... aorta and other large vessels was reduced as compared to 90 healthy subjects. Blacher et al. [15] showed that in patients on hemodialysis aortic stiffness increases the risk of total and cardiovascular mortality. It results in the rise of arterial blood pressure, which is the direct cause for increa ...
Progression of Aortic Stenosis
... are no reliable clinical predictors to help us identify into which subgroup an individual patient will fall. Although it is generally accepted that patients presenting for coronary artery bypass grafting with moderate or severe aortic stenosis (regardless of symptom status) undergo concomitant aorti ...
... are no reliable clinical predictors to help us identify into which subgroup an individual patient will fall. Although it is generally accepted that patients presenting for coronary artery bypass grafting with moderate or severe aortic stenosis (regardless of symptom status) undergo concomitant aorti ...
outline31107
... Conjugate, horizontal-torsional, increases with fixation attempt, progression from pendular to jerk, family history often positive, constant, conjugate, with or without associated sensory system deficits (e.g., alhinism, achromatopsia), associated strabismus or refractive error, decreases with conve ...
... Conjugate, horizontal-torsional, increases with fixation attempt, progression from pendular to jerk, family history often positive, constant, conjugate, with or without associated sensory system deficits (e.g., alhinism, achromatopsia), associated strabismus or refractive error, decreases with conve ...
Case Report: Congenital sub mitral left ventricle aneurysm with
... many years5].In our patient mitral valve was ...
... many years5].In our patient mitral valve was ...
PHACE Syndrome Handbook: A Guide for
... PHACE syndrome have been identified; with every child diagnosed with PHACE syndrome, we discover more about this condition. Every child diagnosed with PHACE syndrome has a different combination of abnormalities associated with the syndrome. Not every affected child has all of the same symptoms, and ...
... PHACE syndrome have been identified; with every child diagnosed with PHACE syndrome, we discover more about this condition. Every child diagnosed with PHACE syndrome has a different combination of abnormalities associated with the syndrome. Not every affected child has all of the same symptoms, and ...
Minimally Invasive Aortic Valve Replacement 1
... of sonar that they invented back in World War II to look for things in the water. Basically, you use sound waves to bounce off the tissues in the body. Those sound waves bounce back to a transducer, and the computer puts together those sound waves in a two-dimensional picture and allows us to see st ...
... of sonar that they invented back in World War II to look for things in the water. Basically, you use sound waves to bounce off the tissues in the body. Those sound waves bounce back to a transducer, and the computer puts together those sound waves in a two-dimensional picture and allows us to see st ...
Simultaneous Bilateral Subdural Hygromas
... dehydration in the elderly, lymphoma, and connective tissue diseases. Differentiation of subdural hygroma from subdural hematoma on imaging can be difficult and gadoliniumenhanced MRI is the imaging modality of choice.3 Empty sella syndrome is divided broadly into primary empty sella, a congenital d ...
... dehydration in the elderly, lymphoma, and connective tissue diseases. Differentiation of subdural hygroma from subdural hematoma on imaging can be difficult and gadoliniumenhanced MRI is the imaging modality of choice.3 Empty sella syndrome is divided broadly into primary empty sella, a congenital d ...
Is It Reasonable to Treat All Calcified Stenotic Aortic Valves
... Recourse to percutaneous AVI is expected to increase in the future. However, the actual clinical experience remains limited, and many problems need to be solved. Aside from coronary obstruction and perivalvular leakage, conservation of the native aortic valve may lead to other, still unknown complic ...
... Recourse to percutaneous AVI is expected to increase in the future. However, the actual clinical experience remains limited, and many problems need to be solved. Aside from coronary obstruction and perivalvular leakage, conservation of the native aortic valve may lead to other, still unknown complic ...
Marfan syndrome
Marfan syndrome (also called Marfan's syndrome) is a genetic disorder of connective tissue. It has a variable clinical presentation, ranging from mild to severe systemic disease. The most serious manifestations involve defects of the heart valves and aorta, which may lead to early death if not properly managed. The syndrome also may affect the lungs, eyes, dural sac surrounding the spinal cord, the skeleton, and the hard palate. People with Marfan syndrome tend to be unusually tall, with long limbs and long, thin fingers and toes.The syndrome is caused by the misfolding of fibrillin-1, a glycoprotein which forms elastic fibers in connective tissue and contributes to cell signaling activity by binding to and sequestering transforming growth factor beta (TGF-β). The mutated fibrillin binds poorly to TGF-β, which results in an accumulation of excess TGF-β in the lungs, heart valves, and aorta. This in turn causes abnormal structure and function of vascular smooth muscle and reduced integrity of the extracellular matrix, which weaken the tissues and cause the features of Marfan syndrome.Named after Antoine Marfan, the French pediatrician who first described the condition in 1896, the disease is an autosomal dominant disorder. Management often includes the use of angiotensin II receptor antagonists (ARBs) and beta blockers.