Proximal Aortic Distensibility Is an Independent Predictor of All
... independent 2-fold higher risk of hard CVD events. Decreased AAD was associated with CV events in low to intermediateCVD risk individuals with an HR for the first quintile of AAD of 5.3 (p ¼ 0.03) as well as with incident HF but not after full ...
... independent 2-fold higher risk of hard CVD events. Decreased AAD was associated with CV events in low to intermediateCVD risk individuals with an HR for the first quintile of AAD of 5.3 (p ¼ 0.03) as well as with incident HF but not after full ...
Cardiac Murmurs
... Diastolic regurgitant murmurs, which include aortic regurgitation murmurs and pulmonic valve regurgitation murmurs, result from retrograde flow across an incompetent valve. Diastolic filling murmurs, such as the murmur of mitral stenosis, result from turbulent flow across a valve (typically the mitr ...
... Diastolic regurgitant murmurs, which include aortic regurgitation murmurs and pulmonic valve regurgitation murmurs, result from retrograde flow across an incompetent valve. Diastolic filling murmurs, such as the murmur of mitral stenosis, result from turbulent flow across a valve (typically the mitr ...
Lecture Outline - Open.Michigan
... • Protrusion of MV leaflets into LA during systole; more common in women • Valve changes ...
... • Protrusion of MV leaflets into LA during systole; more common in women • Valve changes ...
Original Article - Circulation: Arrhythmia and Electrophysiology
... with SSS were diagnosed using the most recently available respective criteria.18,19 Epidemiological data of nonfamilial SSS (n=538) were obtained from the most recent databases of 4 Japanese institutions, in which SSS cases with a family history of pacemaker implantation, sudden death, or underlying ...
... with SSS were diagnosed using the most recently available respective criteria.18,19 Epidemiological data of nonfamilial SSS (n=538) were obtained from the most recent databases of 4 Japanese institutions, in which SSS cases with a family history of pacemaker implantation, sudden death, or underlying ...
Aortic Valve and Ascending Aorta Guidelines for Management and
... area, and energy loss); (3) durability, measured as freedom from structural valve deterioration; (4) event-free survival; and (5) ease of procedure. For aortic valve procedures to be accepted into general practice, however, by interventional cardiologists and surgeons, the sequence of steps would en ...
... area, and energy loss); (3) durability, measured as freedom from structural valve deterioration; (4) event-free survival; and (5) ease of procedure. For aortic valve procedures to be accepted into general practice, however, by interventional cardiologists and surgeons, the sequence of steps would en ...
Heart to Heart: Inherited Cardiovascular
... Genetic testing can aid clinical management by enabling more accurate diagnosis and risk assessment, and in some cases guiding the choice of treatment. Importantly, identification of a mutation in an affected person enables their relatives to be offered targeted testing for the same mutation. Those ...
... Genetic testing can aid clinical management by enabling more accurate diagnosis and risk assessment, and in some cases guiding the choice of treatment. Importantly, identification of a mutation in an affected person enables their relatives to be offered targeted testing for the same mutation. Those ...
Superior Vena Cava Syndrome
... inspection. The variety of collateral circulation and the differences in the venous rearrangement are expression of the SVC obstruction site (Figure 3,4,5). The anatomic classification includes three levels of obstruction: 1. Obstruction of the upper SVC, proximal to the azygos entry point. 2. Obstr ...
... inspection. The variety of collateral circulation and the differences in the venous rearrangement are expression of the SVC obstruction site (Figure 3,4,5). The anatomic classification includes three levels of obstruction: 1. Obstruction of the upper SVC, proximal to the azygos entry point. 2. Obstr ...
Aortic Stenosis: Pathophysiology, Diagnosis, and Medical Management of
... THERESA CARY, RN, MSN, ACNS-BC, CCRN, CHFN JUDITH PEARCE, RN, BSN, CCRN As the average lifespan continues to increase, nurses are managing more patients with aortic stenosis. When an asymptomatic patient begins to manifest signs and symptoms due to progressive narrowing and stiffening of the aortic ...
... THERESA CARY, RN, MSN, ACNS-BC, CCRN, CHFN JUDITH PEARCE, RN, BSN, CCRN As the average lifespan continues to increase, nurses are managing more patients with aortic stenosis. When an asymptomatic patient begins to manifest signs and symptoms due to progressive narrowing and stiffening of the aortic ...
Brugada Syndrome (2015)
... Brugada ECG pattern do not have a known mutation. (21) The majority of mutations in BrS are novel, found in single individuals or single families. Genotype‐phenotype correlations are mostly still unavailable.(22) Mutations often demonstrate incomplete disease penetrance and sign ...
... Brugada ECG pattern do not have a known mutation. (21) The majority of mutations in BrS are novel, found in single individuals or single families. Genotype‐phenotype correlations are mostly still unavailable.(22) Mutations often demonstrate incomplete disease penetrance and sign ...
An Improved Method for Echographic Detection of Left
... Ani echographic "sweep' of the left ventricular outflow tract utilizing a continuous strip) chart recorder (record not retoulched). Area A is the central region of the left ventricle (LV) and is characterized by the echoes from the interve ntricuilar septum (IVS), left ventricular posterior wall (LV ...
... Ani echographic "sweep' of the left ventricular outflow tract utilizing a continuous strip) chart recorder (record not retoulched). Area A is the central region of the left ventricle (LV) and is characterized by the echoes from the interve ntricuilar septum (IVS), left ventricular posterior wall (LV ...
the carotid pulse i: diagnosis of aortic stenosis by external
... not seen, particularly in the more severe cases. To achieve a high level of accuracy in diagnosis, it has proved necessary to consider three aspects of the pulse-the contour, the upstroke time, and the ejection time. Analysed in this way, aortic stenosis could be recognized in 32 out of 33 patients, ...
... not seen, particularly in the more severe cases. To achieve a high level of accuracy in diagnosis, it has proved necessary to consider three aspects of the pulse-the contour, the upstroke time, and the ejection time. Analysed in this way, aortic stenosis could be recognized in 32 out of 33 patients, ...
What Do You Mean by Aortic Valve Area: Geometric Orifice Area
... area or anatomic area (GOA), depending on the technique used to assess stenosis severity (Table II). The differences between these three AVA values depend mainly on the valve inflow shape and the cross-sectional area of the ascending aorta: the discrepancy between Doppler echocardiography and cathet ...
... area or anatomic area (GOA), depending on the technique used to assess stenosis severity (Table II). The differences between these three AVA values depend mainly on the valve inflow shape and the cross-sectional area of the ascending aorta: the discrepancy between Doppler echocardiography and cathet ...
Slide 1
... • 1. When the patient lying on his or her stomach, and propped up on the elbows. Also this position is useful to detect a pericardial friction rub. • 2. The patient standing, leaning forward with his/her hands on the wall. • The great majority of murmurs of aortic regurgitation are heard louder at t ...
... • 1. When the patient lying on his or her stomach, and propped up on the elbows. Also this position is useful to detect a pericardial friction rub. • 2. The patient standing, leaning forward with his/her hands on the wall. • The great majority of murmurs of aortic regurgitation are heard louder at t ...
PDF
... can occur, depending on the severity of the obstruction. Clinical outcome varies from mild systemic hypertension to serious heart failure and death. the clinical manifestations are variable and so is the age of diagnosis. A rapid progression with heart failure can be seen in the neonate, but sometim ...
... can occur, depending on the severity of the obstruction. Clinical outcome varies from mild systemic hypertension to serious heart failure and death. the clinical manifestations are variable and so is the age of diagnosis. A rapid progression with heart failure can be seen in the neonate, but sometim ...
Diagnosis of Pupillary Disorders
... Lower concentrations of phenylephrine (about 2%) are well suited to the pharmacologic detection of weakened pupillary dilators. Among infants, one often finds an anisocoria with normal pupillary light reactions and no ptosis that persists after instillation of topical cocaine. If the anisocoria pers ...
... Lower concentrations of phenylephrine (about 2%) are well suited to the pharmacologic detection of weakened pupillary dilators. Among infants, one often finds an anisocoria with normal pupillary light reactions and no ptosis that persists after instillation of topical cocaine. If the anisocoria pers ...
Almanac 2011: Valvular Heart Disease. The National Society
... Additional data indicate that reducing plasma lipid levels by genetic inactivation of the MTTP gene in hypercholesterolaemic mice with early aortic valve disease normalises oxidative stress, reduces proosteogenic signalling and halts the progression of aortic valve stenosis. 34 Patients with AS and ...
... Additional data indicate that reducing plasma lipid levels by genetic inactivation of the MTTP gene in hypercholesterolaemic mice with early aortic valve disease normalises oxidative stress, reduces proosteogenic signalling and halts the progression of aortic valve stenosis. 34 Patients with AS and ...
Impacts of aortic stenosis and hypertension on left ventricular
... It has been reported that 30–40% of patients with aortic stenosis are hypertensive. In such patients, the left ventricle faces a double (i.e. valvular and vascular) pressure overload, which results in subsequent wall volume hypertrophy. From a clinical standpoint, it is difficult to separate the resp ...
... It has been reported that 30–40% of patients with aortic stenosis are hypertensive. In such patients, the left ventricle faces a double (i.e. valvular and vascular) pressure overload, which results in subsequent wall volume hypertrophy. From a clinical standpoint, it is difficult to separate the resp ...
The Aortomitral Angle is Suspended by the Anterior Mitral Basal “Stay”
... annulus plane was defined as plane that included both FTs (T1 and T2) and the middle of the posterior mitral annulus (PMA). The aortic annulus plane was defined as plane incorporating both FTs (T1 and T2) and the lowest point of the RCS (Fig. 2). Both planes defined the base of the heart with the hi ...
... annulus plane was defined as plane that included both FTs (T1 and T2) and the middle of the posterior mitral annulus (PMA). The aortic annulus plane was defined as plane incorporating both FTs (T1 and T2) and the lowest point of the RCS (Fig. 2). Both planes defined the base of the heart with the hi ...
СARRENT ISSUES OF THE AORTIC FUNCTIONAL MORPHOLOGY
... of the lack of morphological evidence that account for a number of postoperative complications and the ways to prevent them. The other problem that runs through a lot of recent articles is an insufficient presentation of interaction of the heart and aorta lymphatic and nervous apparatuses. When the ...
... of the lack of morphological evidence that account for a number of postoperative complications and the ways to prevent them. The other problem that runs through a lot of recent articles is an insufficient presentation of interaction of the heart and aorta lymphatic and nervous apparatuses. When the ...
Transcatheter Aortic Valve Implantation for Aortic Stenosis
... randomized trials have compared the self-expandable valve with best medical therapy. However, results from the single-arm CoreValve Extreme Risk Pivotal Trial met the authors’ prespecified objective performance goal. The evidence is sufficient to determine qualitatively that the technology results i ...
... randomized trials have compared the self-expandable valve with best medical therapy. However, results from the single-arm CoreValve Extreme Risk Pivotal Trial met the authors’ prespecified objective performance goal. The evidence is sufficient to determine qualitatively that the technology results i ...
Carrent issues of the aortic functional morphology
... problem of the lack of morphological evidence that account for a number of postoperative complications and the ways to prevent them. The other problem that runs through a lot of recent articles is an insufficient presentation of interaction of the heart and aorta lymphatic and nervous apparatuses. W ...
... problem of the lack of morphological evidence that account for a number of postoperative complications and the ways to prevent them. The other problem that runs through a lot of recent articles is an insufficient presentation of interaction of the heart and aorta lymphatic and nervous apparatuses. W ...
Bicuspid Aortic Valve Is Associated With Altered Wall Shear Stress
... significantly elevated WSS occurred for both the nonstenotic and the stenotic RL BAV patient groups compared with the age/ size controls. All RL BAV subgroups were significantly elevated compared with the age/size controls for the circumferentially averaged WSSsystole (P<0.001) and WSSt_avg (P<0.05 ...
... significantly elevated WSS occurred for both the nonstenotic and the stenotic RL BAV patient groups compared with the age/ size controls. All RL BAV subgroups were significantly elevated compared with the age/size controls for the circumferentially averaged WSSsystole (P<0.001) and WSSt_avg (P<0.05 ...
Brugada Syndrome - Circulation: Arrhythmia and Electrophysiology
... The prevalence of BrS appears to be low in the general population. According to recent studies in Europe, the incidence of sudden death in the general population (age 7–64 years) is 1.34 per 100 000 per year,51 and ≈5% show no structural heart abnormality.52 Extensive familial examination of such ca ...
... The prevalence of BrS appears to be low in the general population. According to recent studies in Europe, the incidence of sudden death in the general population (age 7–64 years) is 1.34 per 100 000 per year,51 and ≈5% show no structural heart abnormality.52 Extensive familial examination of such ca ...
Aortic stenosis: Who should undergo surgery, transcatheter valve
... the Western world, affects mainly people over age 60. It is characterized by years to decades of slow progression followed by rapid clinical deterioration and a high death rate once symptoms develop. Drug therapy for it remains ineffective, and surgical aortic valve replacement is the only effective ...
... the Western world, affects mainly people over age 60. It is characterized by years to decades of slow progression followed by rapid clinical deterioration and a high death rate once symptoms develop. Drug therapy for it remains ineffective, and surgical aortic valve replacement is the only effective ...
Marfan syndrome
Marfan syndrome (also called Marfan's syndrome) is a genetic disorder of connective tissue. It has a variable clinical presentation, ranging from mild to severe systemic disease. The most serious manifestations involve defects of the heart valves and aorta, which may lead to early death if not properly managed. The syndrome also may affect the lungs, eyes, dural sac surrounding the spinal cord, the skeleton, and the hard palate. People with Marfan syndrome tend to be unusually tall, with long limbs and long, thin fingers and toes.The syndrome is caused by the misfolding of fibrillin-1, a glycoprotein which forms elastic fibers in connective tissue and contributes to cell signaling activity by binding to and sequestering transforming growth factor beta (TGF-β). The mutated fibrillin binds poorly to TGF-β, which results in an accumulation of excess TGF-β in the lungs, heart valves, and aorta. This in turn causes abnormal structure and function of vascular smooth muscle and reduced integrity of the extracellular matrix, which weaken the tissues and cause the features of Marfan syndrome.Named after Antoine Marfan, the French pediatrician who first described the condition in 1896, the disease is an autosomal dominant disorder. Management often includes the use of angiotensin II receptor antagonists (ARBs) and beta blockers.