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A review of hepatitis B virus infection in Sri Lanka
A review of hepatitis B virus infection in Sri Lanka

... The exact incidence or prevalence of HBV in the general population of Sri Lanka is unknown. Seroepidemiological studies carried out in the country indicate that the prevalence of HBsAg varies between 0.1 to 2.5%.12 Most studies carried out in Sri Lanka tend to concentrate on risk groups rather than ...
PATHOGEN SAFETY DATA SHEET Herpes Simplex Virus
PATHOGEN SAFETY DATA SHEET Herpes Simplex Virus

... Notify others working in the lab. Remove and don new PPE. Cover area of the spill with absorbent material and add 10 % Bleach. Allow 30 minutes hour of contact time. After 30 minutes and then cleanup and dispose of materials. ...
here - Wilbarger General Hospital
here - Wilbarger General Hospital

A Simulation Model Including Vaccination and
A Simulation Model Including Vaccination and

... which, it is dependent their capacity to generate severe forms of the disease. From a public health care point of view the most important virus is type A. This one may drive to pandemics associated with high mobility, high number of deaths due to the virus, and social and economic disruptions. This ...
IV Medicine Administration: Infection Control
IV Medicine Administration: Infection Control

1 - Norcross High School
1 - Norcross High School

... 12. What information does a karyotype give you? PICTURE OF CHROMOSOMES THAT CAN TELL YOU THE SEX OF THE ORGANISM AND IF IT HAS ANY GENETIC DISEASES. 13. How many chromosomes do human somatic cells have? 46 14. How many chromosomes do human sex cells have? 23 15. What are the sex chromosomes for male ...
CNS Viral Infections (Johnson) - Johns Hopkins Bloomberg School
CNS Viral Infections (Johnson) - Johns Hopkins Bloomberg School

... Most represent uncommon complications of common systemic infections Over 100 etiologic agents (some are not viruses) Spectrum of agents and syndromes overlap Most IMPORTANT: − Rule out non-viral causes that require specific treatment − Do not miss herpes simplex encephalitis, which has highly effect ...
October 9, 2014
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Communicable disease - Roads and Maritime Services
Communicable disease - Roads and Maritime Services

... become active when the body’s defences are lower. People who spend long periods of time in close contact with a person with infectious TB of the lung or respiratory tract and those who have a chronic illness that affects their immune system are at risk. People with TB in their lungs and throat can b ...
Streptococcus pneumoniae
Streptococcus pneumoniae

... S. pneumoniae was isolated independently by Pasteur and Steinberg more than 100 years ago. ...
Chapter 14 Study Guide Microbiology (Bauman 2007)
Chapter 14 Study Guide Microbiology (Bauman 2007)

... following learning objectives in mind. Once you have mastered this chapter, you should be able to: * Distinguish among the types of symbiosis, listing them in order from most beneficial to most harmful for the host. * Describe the relationships among the terms: parasite, host , and pathogen . * Desc ...
Table 1 - Creating Family Wellness
Table 1 - Creating Family Wellness

... Immunologic Abnormalities Reported for CFS • Elevated levels of antibodies to viral proteins. • Decreased natural killer cell activity. • Low or elevated antibody levels. • Increased or decreased levels of circulating immune complexes. • Increased cytokin (e.g., interleukin2)levels. • Decreased inte ...
Hepatitis B and Hepatitis C: Whom to Test
Hepatitis B and Hepatitis C: Whom to Test

... needlestick injury to a healthcare worker) II. Populations recommended for hepatitis B vaccination, without pre-vaccination serology1  Persons under 19 years of age who have not been vaccinated against hepatitis B  Persons having more than one (>1) sexual partner in the past six months  Persons s ...
Immune Reconstitution - UCLA Center for World Health
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... regiment combines three or more different drugs. Can virus be cleared by HAART and why? HAART regiments can reduce the amount of active virus and in some case can lower the number of virus until it is undetectable by current blood testing techniques. However, usual HAART treatment cannot clear HIV i ...
WASH and HIV: current research and opportunities
WASH and HIV: current research and opportunities

... of hospitalization, long-term illness, and death as a result of WASH-related infections • Children who are HIV+, as well as those who are HIV- but cared for by mothers that are HIV+, are at greater risk of poor nutritional status and health which can be caused or aggravated by enteric infection (Fil ...
Gender differences wrt immune responses
Gender differences wrt immune responses

... • estrogen is capable of triggering SLE-like autoimmunity (mice) • Additionally, androgens such as testosterone clearly play an important role in some autoimmune diseases • Female NOD mice are much more susceptible to spontaneous ...
Importance of Infection Control Measures in
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... Further to our letter dated 30 July 2014, we would like to provide further updates on the latest situation of the outbreak of Ebola Virus Disease (EVD). As of 30 July 2014, there have been 1,440 EVD cases and 826 deaths in West Africa. Latest distribution of cases has been uploaded to the Centre for ...
Seattle/Kenya Collaboration- MTCT
Seattle/Kenya Collaboration- MTCT

... • A major focus of HIV vaccine efforts is trying to elicit HIVspecific NAbs. • Most successful vaccines are thought to work through antibody-mediated protection. • Do NAbs protect against HIV? ...
Use of steroids for prolonged cholestasis secondary to
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Danielle M. Tufts , Kyle Spencer , Wayne Hunter , and Blake Bextine
Danielle M. Tufts , Kyle Spencer , Wayne Hunter , and Blake Bextine

... sense RNA, and are between 7.2 and 9.0 kb long (Mettenleiter and Sobrino 2008). Solenopsis invicta virus (SINV-1) is in the Dicistroviridae subgroup, only infectious to S. invicta (Fig. 3) (Valles et al. 2007). The genome of this SINV-1 is 8026 nucleotides long, has a polyadenylated tail, and includ ...
57. Expression of receptors during the host immune response to FMDV
57. Expression of receptors during the host immune response to FMDV

... selected at random and inoculated by subepidermo-lingual injection of approximately 0.5 ml of FMDV O UKG 34/2001 as described elsewhere (Alexandersen et al., 2003a, Zhang et al., 2004) while the other half of the animals were kept as direct contacts throughout the experiment. After inoculation, anim ...
Introduction to Viral Diseases of Fish 1
Introduction to Viral Diseases of Fish 1

... that a virus is responsible. Three techniques are used for initial identification of a virus. First, electron microscopy (EM) is used to visualize virus particles within tissue cells. Second, an effort is made to grow the virus in the laboratory using established cell-lines, which are living cells g ...
Approach to lymphadenopathy
Approach to lymphadenopathy

... macrophages, leading to enlargement of nodes. There may also be localized infiltration by inflammatory cells in response to an infection of the nodes themselves. This is known as a lymphadenitis. Finally, it is crucial to rule out rarer, more serious causes such as lymphomas or leukemias, which are ...
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Hepatitis B



Hepatitis B is an infectious disease caused by the hepatitis B virus (HBV) which affects the liver. It can cause both acute and chronic infections. Many people have no symptoms during the initial infection. Some develop a rapid onset of sickness with vomiting, yellowish skin, feeling tired, dark urine and abdominal pain. Often these symptoms last a few weeks and rarely does the initial infection result in death. It may take 30 to 180 days for symptoms to begin. In those who get infected around the time of birth 90% develop chronic hepatitis B while less than 10% of those infected after the age of five do. Most of those with chronic disease have no symptoms; however, cirrhosis and liver cancer may eventually develop. These complications results in the death of 15 to 25% of those with chronic disease.The virus is transmitted by exposure to infectious blood or body fluids. Infection around the time of birth or from contact with other people's blood during childhood is the most frequent method by which hepatitis B is acquired in areas where the disease is common. In areas where the disease is rare, intravenous drug use and sexual intercourse are the most frequent routes of infection. Other risk factors include working in healthcare, blood transfusions, dialysis, living with an infected person, travel in countries where the infection rate is high, and living in an institution. Tattooing and acupuncture led to a significant number of cases in the 1980s; however, this has become less common with improved sterility. The hepatitis B viruses cannot be spread by holding hands, sharing eating utensils, kissing, hugging, coughing, sneezing, or breastfeeding. The infection can be diagnosed 30 to 60 days after exposure. Diagnosis is typically by testing the blood for parts of the virus and for antibodies against the virus. It is one of five known hepatitis viruses: A, B, C, D, and E.The infection has been preventable by vaccination since 1982. Vaccination is recommended by the World Health Organization in the first day of life if possible. Two or three more doses are required at a later time for full effect. This vaccine works about 95% of the time. About 180 countries gave the vaccine as part of national programs as of 2006. It is also recommended that all blood be tested for hepatitis B before transfusion and condoms be used to prevent infection. During an initial infection, care is based on the symptoms that a person has. In those who develop chronic disease antiviral medication such as tenofovir or interferon maybe useful, however these drugs are expensive. Liver transplantation is sometimes used for cirrhosis.About a third of the world population has been infected at one point in their lives, including 240 million to 350 million who have chronic infections. Over 750,000 people die of hepatitis B each year. About 300,000 of these are due to liver cancer. The disease is now only common in East Asia and sub-Saharan Africa where between 5 and 10% of adults have chronic disease. Rates in Europe and North America are less than 1%. It was originally known as serum hepatitis. Research is looking to create foods that contain HBV vaccine. The disease may affect other great apes as well.
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