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P - World Congress on Virology
P - World Congress on Virology

... An ideal vaccine stimulates four components of the immune system. 1) Elicit neutralizing antibody at high titer. 2) Stimulate a cellular (T-Cell) immune response, especially cytotoxic T-cells. 3) Stimulate mucosal immunity. 4) Provoke the innate immune system. ...
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slide1_medical-virology-1

... 3. Small size: viruses are smaller than other organisms, vary in size (diameter) from 10 nm - 300 nm. 4. Genome: either DNA or RNA. The nucleic acid is encased in a protein shell, which may be surrounded by a lipid – containing membrane. The entire infectious unit is termed a virion. ...
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TB - Columbia University
TB - Columbia University

... HIV infection Tuberculin skin test conversion Fibrotic lesions (on chest X-ray) consistent with old, healed TB Injection drug use Diabetes mellitus Prolonged high-dose corticosteroid therapy or other intensive immunosuppressive therapy Chronic renal failure Some hematologic disorders, such as leukem ...
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... 3. Small size: viruses are smaller than other organisms, vary in size (diameter) from 0 nm - 300 nm. 4. Genome: either DNA or RNA. The nucleic acid is encased in a protein shell, which may be surrounded by a lipid – containing membrane. The entire infectious unit is termed a virion. ...
Standing orders for administering hepatitis B vaccine to adults
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Ebola Virus Disease (EVD) Fact Sheet for Health Professionals
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Lecture Notes: How Does Infection Occur?

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... The virus then invades the sub-epithelial tissues and reaches the lymphatic system and the blood stream . The virus then spreads by blood and infects the endothelial cells of the blood vessels. The cytotoxic T-cells attack virus infected vascular endothelial cells. And this will lead to the developm ...
A Prospective Study of Transfusion-Transmitted GB Virus C Infection
A Prospective Study of Transfusion-Transmitted GB Virus C Infection

... seven were positive at both first and 6-month posttransfusion samples, three were positive at 6 months, and one was positive at the first posttransfusion samples only. Therefore, to avoid including recipients with carry-over rather than true infection and to save the resources and time of so manyPCR ...
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... Critical Gaps in the Viral Hepatitis Response  Viral hepatitis infections are increasing rather than moving toward elimination because of the opioid epidemic.  There are critical gaps in the response to viral hepatitis that make elimination difficult.  Existing resources do not support active su ...
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... The clinical spectrum of acute infection caused by human immunodeficiency virus type 1 (HIV-1), which is also referred to as acute HIV infection, acute retroviral syndrome, HIV seroconversion syndrome, or primary HIV infection, ranges from asymptomatic seroconversion to a severe symptomatic illness ...
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... A bloodborne exposure occurs when a patient’s infectious body fluids enter the blood stream of our employee. The most common way this happens is that a needle which has entered the patients skin then punctures our employees skin. Exposure can also occur if the patient’s body fluids come in contact w ...
Cytokine and Chemokine Gene Expression after Primary and
Cytokine and Chemokine Gene Expression after Primary and

... tions per time point, and the duration of study. With the exception of IL-10, the expression of which did not begin until postinfection day 2, all the remaining genes examined (GRO, IFN-a, IFN-g, IL-1b, IL-6, IP-10, MIP-1b, RANTES, and TNF-a) showed increased expression within 24 h of infection. Suc ...
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Influenza epidemic spread simulation for Poland a large

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(HBV) in a Case of HBV Infection Acquir

... of genetic distance and phylogenetic tree analysis have been used recently to determine the transmission route of viral infection. Molecular evolutionary analysis of the route of infection was first used in a study of the transmission pattern of HIV in one dental practice [15]. After that study, HCV ...
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Hepatitis B



Hepatitis B is an infectious disease caused by the hepatitis B virus (HBV) which affects the liver. It can cause both acute and chronic infections. Many people have no symptoms during the initial infection. Some develop a rapid onset of sickness with vomiting, yellowish skin, feeling tired, dark urine and abdominal pain. Often these symptoms last a few weeks and rarely does the initial infection result in death. It may take 30 to 180 days for symptoms to begin. In those who get infected around the time of birth 90% develop chronic hepatitis B while less than 10% of those infected after the age of five do. Most of those with chronic disease have no symptoms; however, cirrhosis and liver cancer may eventually develop. These complications results in the death of 15 to 25% of those with chronic disease.The virus is transmitted by exposure to infectious blood or body fluids. Infection around the time of birth or from contact with other people's blood during childhood is the most frequent method by which hepatitis B is acquired in areas where the disease is common. In areas where the disease is rare, intravenous drug use and sexual intercourse are the most frequent routes of infection. Other risk factors include working in healthcare, blood transfusions, dialysis, living with an infected person, travel in countries where the infection rate is high, and living in an institution. Tattooing and acupuncture led to a significant number of cases in the 1980s; however, this has become less common with improved sterility. The hepatitis B viruses cannot be spread by holding hands, sharing eating utensils, kissing, hugging, coughing, sneezing, or breastfeeding. The infection can be diagnosed 30 to 60 days after exposure. Diagnosis is typically by testing the blood for parts of the virus and for antibodies against the virus. It is one of five known hepatitis viruses: A, B, C, D, and E.The infection has been preventable by vaccination since 1982. Vaccination is recommended by the World Health Organization in the first day of life if possible. Two or three more doses are required at a later time for full effect. This vaccine works about 95% of the time. About 180 countries gave the vaccine as part of national programs as of 2006. It is also recommended that all blood be tested for hepatitis B before transfusion and condoms be used to prevent infection. During an initial infection, care is based on the symptoms that a person has. In those who develop chronic disease antiviral medication such as tenofovir or interferon maybe useful, however these drugs are expensive. Liver transplantation is sometimes used for cirrhosis.About a third of the world population has been infected at one point in their lives, including 240 million to 350 million who have chronic infections. Over 750,000 people die of hepatitis B each year. About 300,000 of these are due to liver cancer. The disease is now only common in East Asia and sub-Saharan Africa where between 5 and 10% of adults have chronic disease. Rates in Europe and North America are less than 1%. It was originally known as serum hepatitis. Research is looking to create foods that contain HBV vaccine. The disease may affect other great apes as well.
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