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Gastro-oesophageal reflux disease and dyspepsia in adults
Gastro-oesophageal reflux disease and dyspepsia in adults

... important to note that children and young people (younger than 18 years) and people with a diagnosis of oesophagogastric cancer are not covered in this guideline update. In this guideline, specialist care is defined as treatment decisions made by a consultant-led service in secondary or tertiary car ...
Communicable Disease (Public Health Laboratories) Part 1
Communicable Disease (Public Health Laboratories) Part 1

... unique and specialized roles. A public health laboratory is one type of specialized medical laboratory. A certain level of redundancy amongst laboratories is also needed for instances where vulnerable areas may risk collapse and ongoing services (business continuity) are critical. Medical laboratori ...
hemorrhoids - Coastal Digestive Diseases, PC
hemorrhoids - Coastal Digestive Diseases, PC

... The National Digestive Diseases Information Clearinghouse (NDDIC) is a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The NIDDK is part of the National Institutes of Health of the U.S. Department of Health and Human Services. Established in 1980, the Clearin ...
National Guideline for the Control and Management of Sickle Cell
National Guideline for the Control and Management of Sickle Cell

... Sickle cell disease (SCD) is one of the top ten (10) non-communicable diseases (NCDs) in Nigeria causing significant morbidity and mortality and consequently undermining the attainment of the Millennium Development Goals (MDGs) 4, 5 and 6. SCD is particularly associated with increased maternal, neon ...
Dysphagia November 2001
Dysphagia November 2001

... identify vallecular stasis. The advantages of the study are that it uses no radiation, is portable, and normal food can be used. The disadvantages are that it is not widely available and the study is segmental in nature so that anatomic detail is poor. Flexible Endoscopic Evaluation of Swallowing (F ...
Facing - Johns Hopkins Medicine
Facing - Johns Hopkins Medicine

... existing NHLBI cohorts to enable analyses that were not possible before. The results of a new study led by Wendy Post, MD, show that people infected with the hepatitis C virus are at risk for more than liver damage: the infection may also spell heart trouble. The findings, published online July 27 i ...
- American Journal of Kidney Diseases
- American Journal of Kidney Diseases

... (bottom) 15 for PKD2. The coding regions are shaded; 50 and 30 untranslated regions are not shaded. Reproduced from Torres et al (“Autosomal dominant polycystic kidney disease.” Lancet. 2007;369(9569):1287-1301) with permission of Elsevier. (B) Predicted structures of polycystin 1 (PC1) and polycyst ...
GOUT
GOUT

... some other factors. With or without treatment, the symptoms usually go away within 3 to 10 days, and the next attack may not occur for months or even years, if at all. However, over time attacks can become more severe, last longer, and occur more often. There may be a genetic link: many people with ...
Full-text PDF
Full-text PDF

... pass through the marrow-blood barrier, which does not possess histocompatibility antigens. The main effect of such dysfunction is an attack on the immune system cells recognized by the body as foreign cells [41]. Autoimmune diseases also include thyroid dysfunctions such as lymphocytic thyroiditis ( ...
Canadian Heart Health Strategy and Action Plan
Canadian Heart Health Strategy and Action Plan

... As Chair of the Canadian Heart Health Strategy and Action Plan Steering Committee, it is my privilege to submit our final Strategy document, Building a Heart Healthy Canada, and its companion Action Plan. As the leading cause of death and hospitalizations among Canadians, cardiovascular disease is a ...
Handbook on Sickle Cell Disease - English
Handbook on Sickle Cell Disease - English

... a rope-like fiber that aligns with others to form a bundle, distorting the red cell into characteristic sickled forms (Figure 1). These deformed sickle red cells can occlude the micro vascular circulation producing vascular damage, organ infarcts, painful episodes and other symptoms associated with ...
i Regional Surveillance Systems for CAREC Member
i Regional Surveillance Systems for CAREC Member

... Programme Managers, and with inputs from disease prevention and control programmes in the Pan American Health Organization/World Health Organization (PAHO/WHO), with whom our surveillance programmes are congruent, as well as from other public health organizations. Surveillance systems are strengthen ...
Heartburn Understanding and Treating
Heartburn Understanding and Treating

... An internist, just like a family practice or general practice doctor, can serve as your primary care doctor. But internists are unique because they focus on adult medicine. Internists don’t deliver babies, they don’t treat children and they don’t do surgery. They do, however, have wide-ranging knowl ...
Adrenal Insufficiency and Addison`s Disease
Adrenal Insufficiency and Addison`s Disease

... • chronic candida infections, a type of fungal infection • chronic active hepatitis, a liver disease Type 2, sometimes called Schmidt’s syndrome, usually affects young adults and may include • an underactive thyroid gland, which pro­ duces hormones that regulate metabolism • slow sexual develo ...
Transabdominal ultrasound of the gastrointestinal tract
Transabdominal ultrasound of the gastrointestinal tract

... on the other hand have broadened its applications. The spectrum of indications comprises not only acute conditions such as appendicitis, diverticulitis, or bowel obstruction but also a number of subacute and chronic diseases. The ability of US (similar to CT and MRI) to evaluate the transmural infla ...
Pathophysiology and Etiology of Osteoarthritis - e
Pathophysiology and Etiology of Osteoarthritis - e

... Osteoarthritis (OA) is a degenerative joint disease, chronic and progressive, affecting synovial joints mobile [2,12,13] These processes result in different interactions between the joint cartilage and adjacent tissues in response to injury or chondrocyte extracellular matrix [14,15]. This disease c ...
national eye institute - uveitis - VISION 2020 e
national eye institute - uveitis - VISION 2020 e

... diseases can slightly reduce vision or lead to severe vision loss. The term “uveitis” is used because the diseases often affect a part of the eye called the uvea. Nevertheless, uveitis is not limited to the uvea. These diseases also affect the lens, retina, optic nerve, and vitreous, producing reduc ...
Renal Dysfunction After Non-Renal Solid Organ Transplantation
Renal Dysfunction After Non-Renal Solid Organ Transplantation

... GFR estimated from serum creatinine using MDRD Study equation based on age, gender, race and calibration for se-rum creatinine. * N is based on number of individuals in each listed GFR range in NHANES III, 1988–1994. Prevalence and number of individuals estimated by extrapolation to population of US ...
A Diagnostic Approach to Pruritus
A Diagnostic Approach to Pruritus

... pruritus is often overemphasized as an early manifestation of cancer.4,21 Chronic Renal Disease. More than 50 percent of patients with chronic renal disease and up to 80 percent of patients on dialysis have pruritus.2 The pruritus is often generalized, but may be localized to the back.25 Liver Disea ...
Are You at Increased Risk for Chronic Kidney Disease?
Are You at Increased Risk for Chronic Kidney Disease?

... feel sick. You may experience other problems like high blood pressure, anemia, weak bones, poor nutritional health and nerve damage. Anemia means there is a short supply of red blood cells in the body, which can make you feel tired and have little energy. CKD also increases your risk of worsening he ...
Leg ulcers: atypical presentations and associated comorbidities
Leg ulcers: atypical presentations and associated comorbidities

... vessel walls and can affect any blood vessel in any organ. Vasculitis of the skin usually results from the inflammation and ischemia of small- to medium-sized blood vessels 22, 23. Although vasculitis is activated by many factors, current research suggests that the deposition of circulating immune c ...
F2005C00455 F2005C00455 - Federal Register of Legislation
F2005C00455 F2005C00455 - Federal Register of Legislation

... (c) Comparison of products should be factual, fair and capable of substantiation. (d) Advertisements to the general public should help people to make rational decisions on the use of drugs determined to be legally available without prescription. While they should take into account people's legitimat ...
Generalised Pustular Psoriasis
Generalised Pustular Psoriasis

... (von Zumbusch variant) occurs with erythematous lesions producing burning sensation and may be associated with upper respiratory system or other systemic infections. High temperature appears suddenly with shiver and chills. The patient experiences constitutional signs and symptoms. Formation of mult ...
The blue book
The blue book

... been recognised that laboratory notification of infectious diseases should be an integral part of any disease surveillance system. The Health (Infectious Diseases) Regulations 2001 require laboratories to notify tests indicating the probable presence of a human pathogenic organism associated with an ...
Evaluation and management of lymphadenopathy in children.
Evaluation and management of lymphadenopathy in children.

... More indolent causes of lymphadenitis include Bartonella henselae (cat-scratch disease), Mycobacterium tuberculosis, and atypical mycobacteria. With these infections, fluctuant lymph nodes may develop over weeks to months, and tenderness and signs of inflammation frequently are absent. The nontuberc ...
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Disease



A disease is a particular abnormal condition, a disorder of a structure or function, that affects part or all of an organism. The causal study of disease is called pathology. Disease is often construed as a medical condition associated with specific symptoms and signs. It may be caused by factors originally from an external source, such as infectious disease, or it may be caused by internal dysfunctions, such as autoimmune diseases. In humans, ""disease"" is often used more broadly to refer to any condition that causes pain, dysfunction, distress, social problems, or death to the person afflicted, or similar problems for those in contact with the person. In this broader sense, it sometimes includes injuries, disabilities, disorders, syndromes, infections, isolated symptoms, deviant behaviors, and atypical variations of structure and function, while in other contexts and for other purposes these may be considered distinguishable categories. Diseases usually affect people not only physically, but also emotionally, as contracting and living with a disease can alter one's perspective on life, and one's personality.Death due to disease is called death by natural causes. There are four main types of disease: pathogenic disease, deficiency disease, hereditary disease, and physiological disease. Diseases can also be classified as communicable and non-communicable. The deadliest disease in humans is ischemic heart disease (blood flow obstruction), followed by cerebrovascular disease and lower respiratory infections respectively.
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