Morphological Basis of Learning and Memory: Vertebrates
... Greenough (1972) followed up these findings, reporting that visual cortical neurons of rats reared in enriched environments had larger dendritic fields than did those of cage housed controls. Dendrites of neurons receive the bulk of the synaptic input (see Figure 1), so the implication was that new ...
... Greenough (1972) followed up these findings, reporting that visual cortical neurons of rats reared in enriched environments had larger dendritic fields than did those of cage housed controls. Dendrites of neurons receive the bulk of the synaptic input (see Figure 1), so the implication was that new ...
doi:10
... whether neurogenesis occurs in the adult human brain, in regions previously identified as neurogenic in adult rodents and monkeys. Human brain tissue was obtained postmortem from patients who had been treated with the thymidine analog, bromodeoxyuridine (BrdU), that labels DNA during the S phase. Us ...
... whether neurogenesis occurs in the adult human brain, in regions previously identified as neurogenic in adult rodents and monkeys. Human brain tissue was obtained postmortem from patients who had been treated with the thymidine analog, bromodeoxyuridine (BrdU), that labels DNA during the S phase. Us ...
Imaging neurite development of adult
... Felix B. Kleine Borgmann1,2,3, Oliver Bracko1,2,3 and Sebastian Jessberger1,2,3,* SUMMARY Neural stem/progenitor cells (NSPCs) generate new neurons throughout life in the mammalian hippocampus. Newborn granule cells mature over several weeks to functionally integrate into the pre-existing neural cir ...
... Felix B. Kleine Borgmann1,2,3, Oliver Bracko1,2,3 and Sebastian Jessberger1,2,3,* SUMMARY Neural stem/progenitor cells (NSPCs) generate new neurons throughout life in the mammalian hippocampus. Newborn granule cells mature over several weeks to functionally integrate into the pre-existing neural cir ...
Running Improves Pattern Separation during Novel Object
... with 34 ± 4% of the dendrites extending well into the OML, significantly more than in control animals (21 ± 4%, P < 0.05, n = 10 each). Again this effect was largely constrained to the dorsal half of the hippocampus showing 3 times more dendrites in the OML in running animals (Fig. 2G, 34 ± 5% versu ...
... with 34 ± 4% of the dendrites extending well into the OML, significantly more than in control animals (21 ± 4%, P < 0.05, n = 10 each). Again this effect was largely constrained to the dorsal half of the hippocampus showing 3 times more dendrites in the OML in running animals (Fig. 2G, 34 ± 5% versu ...
– Cell loss Brain, Neuron
... neuronal necrosis. Compare this image with those of Figure 2 and Figure 3 depicting the same region of hippocampus in a control animal. The atrophy of this portion of the hippocampus interferes with normal function, notably learning, memory, and spatial recognition processes. Neuronal cell loss due ...
... neuronal necrosis. Compare this image with those of Figure 2 and Figure 3 depicting the same region of hippocampus in a control animal. The atrophy of this portion of the hippocampus interferes with normal function, notably learning, memory, and spatial recognition processes. Neuronal cell loss due ...
Characterization of the Bed Nucleus of the Stria Terminalis
... The bed nucleus of the stria terminalis (BNST) is part of the extended amygdala which receives heavy projections from the basolateral amygdala and other areas, and projects to hypothalamic and brainstem target areas that mediate autonomic and behavioral responses to aversive or threatening stimuli. ...
... The bed nucleus of the stria terminalis (BNST) is part of the extended amygdala which receives heavy projections from the basolateral amygdala and other areas, and projects to hypothalamic and brainstem target areas that mediate autonomic and behavioral responses to aversive or threatening stimuli. ...
GABA suppresses neurogenesis in the adult
... generated hippocampal granule neurons express GABAB receptors. Thirty days after injection of bromodeoxyuridine (BrdU), newborn neurons were identified by BrdU and Calbindin or NeuN immunostaining. BrdU-positive neurons express both GABAB1 and GABAB2 receptor subunits (G,H, arrowheads). (I-K) Expres ...
... generated hippocampal granule neurons express GABAB receptors. Thirty days after injection of bromodeoxyuridine (BrdU), newborn neurons were identified by BrdU and Calbindin or NeuN immunostaining. BrdU-positive neurons express both GABAB1 and GABAB2 receptor subunits (G,H, arrowheads). (I-K) Expres ...
Western blots and quantitative RT-PCR
... BrdU+ cells per mm of subgranular layer (SGL) in old mice was not affected by Ink4a-deficiency (g). The numbers of BrdU+NeuN- non-neuronal cells and BrdU+NeuN+ neurons per mm of dentate gyrus (DG) in old mice were also not significantly affected by Ink4a deficiency (h). Note that control mice appear ...
... BrdU+ cells per mm of subgranular layer (SGL) in old mice was not affected by Ink4a-deficiency (g). The numbers of BrdU+NeuN- non-neuronal cells and BrdU+NeuN+ neurons per mm of dentate gyrus (DG) in old mice were also not significantly affected by Ink4a deficiency (h). Note that control mice appear ...
heledius - Society for the Advancement of Sexual Health
... The ability to transfer previous unconscious processes such as acting out as a result of stress into a conscious process of activating a new and healthier pathway in the brain when stress occurs. This is a result of new neuronal connections in the brain that include the cortex which is the ratio ...
... The ability to transfer previous unconscious processes such as acting out as a result of stress into a conscious process of activating a new and healthier pathway in the brain when stress occurs. This is a result of new neuronal connections in the brain that include the cortex which is the ratio ...
Neurogenesis in adulthood: a possible role in
... requires evidence that a progenitor cell has divided in adulthood and that its daughter cells attain a neuronal phenotype. The classical method of demonstrating cell division is that of 3H-thymidine autoradiography (Ref. a). For in vivo studies, this method involves injecting 3H-thymidine into live ...
... requires evidence that a progenitor cell has divided in adulthood and that its daughter cells attain a neuronal phenotype. The classical method of demonstrating cell division is that of 3H-thymidine autoradiography (Ref. a). For in vivo studies, this method involves injecting 3H-thymidine into live ...
The hidden side of the UPR signalling pathway - Reflexions
... Initially recognized as homeostatic signalling pathway that helps cells to cope with cellular stress, the Unfolded Protein Response (UPR) has kept an unexpected activity well hidden up until now. It would also seem that it plays an important physiological role in the development of the nervous syste ...
... Initially recognized as homeostatic signalling pathway that helps cells to cope with cellular stress, the Unfolded Protein Response (UPR) has kept an unexpected activity well hidden up until now. It would also seem that it plays an important physiological role in the development of the nervous syste ...
SMARCA3, a Chromatin-Remodeling Factor, Is Required for p11
... 20% of the population worldwide. Selective serotonin reuptake inhibitors (SSRIs), the most widely used class of antidepressants, generally take several weeks to show clinical efficacy, in spite of their immediate effect on serotonergic neurotransmission. This therapeutic delay signifies the involvem ...
... 20% of the population worldwide. Selective serotonin reuptake inhibitors (SSRIs), the most widely used class of antidepressants, generally take several weeks to show clinical efficacy, in spite of their immediate effect on serotonergic neurotransmission. This therapeutic delay signifies the involvem ...
BIOLOGY & BEHAVIOR
... because it is the basis of all behavior The NEURON is the fundamental unit of the nervous system ...
... because it is the basis of all behavior The NEURON is the fundamental unit of the nervous system ...
Seven principles in the regulation of adult neurogenesis
... Adult hippocampal neurogenesis attracts so much attention and interest because it has become increasingly clear that the new neurons exert critical functions in the hippocampus and help in explaining particular aspects of learning and memory (Becker & Wojtowicz, 2007; Kempermann, 2008; Appleby & Wis ...
... Adult hippocampal neurogenesis attracts so much attention and interest because it has become increasingly clear that the new neurons exert critical functions in the hippocampus and help in explaining particular aspects of learning and memory (Becker & Wojtowicz, 2007; Kempermann, 2008; Appleby & Wis ...
Reduction of the number of new cells reaching olfactory bulbs
... Neurogenesis in the olfactory bulbs 169 Mammals (as all vertebrates) throughout life constantly add new and remove old OB interneurons (Doetsch et al. 1999, Tramontin et al. 2003). It is postulated that this turnover allows for increased plasticity of the olfactory system and its easier adaptation ...
... Neurogenesis in the olfactory bulbs 169 Mammals (as all vertebrates) throughout life constantly add new and remove old OB interneurons (Doetsch et al. 1999, Tramontin et al. 2003). It is postulated that this turnover allows for increased plasticity of the olfactory system and its easier adaptation ...
Lewis FT 1923 The significance of the term hippocampus. J Comp
... of cerebral substance were being compared with fish or beast, and no one could be sure which end was the head." Lewis FT 1923 The significance of the term hippocampus. J Comp Neurol 35: 213 ...
... of cerebral substance were being compared with fish or beast, and no one could be sure which end was the head." Lewis FT 1923 The significance of the term hippocampus. J Comp Neurol 35: 213 ...
Regulation of Stroke-Induced Neurogenesis in Adult Brain—Recent
... (MCAO), causing infarction in the striatum and cerebral cortex, gives rise to increased cell proliferation in the adult rat subventricular zone (SVZ) (Jin and others 2001; Zhang and others 2001; Zhang R, Zhang Z, Zhang C, and others 2004). The newly formed neuroblasts migrate from the SVZ into the d ...
... (MCAO), causing infarction in the striatum and cerebral cortex, gives rise to increased cell proliferation in the adult rat subventricular zone (SVZ) (Jin and others 2001; Zhang and others 2001; Zhang R, Zhang Z, Zhang C, and others 2004). The newly formed neuroblasts migrate from the SVZ into the d ...
Development & Neuroplasticity - U
... Neurodevelopment • Experience alters neural development in at least 3 different ways: (1) by influencing gene expression for cell adhesion molecules; (2) by influencing the release of neurotrophins (3) and by altering the spontaneous activity of certain brain regions ...
... Neurodevelopment • Experience alters neural development in at least 3 different ways: (1) by influencing gene expression for cell adhesion molecules; (2) by influencing the release of neurotrophins (3) and by altering the spontaneous activity of certain brain regions ...
Slide ()
... The paraventricular nucleus in the hypothalamus is a microcosm of neuroendocrine, autonomic, and sensory-motor integration. The three structuralfunctional divisions of the paraventricular nucleus are shown. The magnocellular neuroendocrine division comprises two distinct although partly interdigitat ...
... The paraventricular nucleus in the hypothalamus is a microcosm of neuroendocrine, autonomic, and sensory-motor integration. The three structuralfunctional divisions of the paraventricular nucleus are shown. The magnocellular neuroendocrine division comprises two distinct although partly interdigitat ...
Slide ()
... The paraventricular nucleus in the hypothalamus is a microcosm of neuroendocrine, autonomic, and sensory-motor integration. The three structuralfunctional divisions of the paraventricular nucleus are shown. The magnocellular neuroendocrine division comprises two distinct although partly interdigitat ...
... The paraventricular nucleus in the hypothalamus is a microcosm of neuroendocrine, autonomic, and sensory-motor integration. The three structuralfunctional divisions of the paraventricular nucleus are shown. The magnocellular neuroendocrine division comprises two distinct although partly interdigitat ...
PDF
... areas during development, so why isn’t lateral inhibition disrupted where these wavefronts contact non-neurogenic tissue? José María Frade, Saúl Ares and colleagues investigate this puzzle on p. 2321. The researchers show that Deltalike 1 (Dll1) is widely expressed by non-neurogenic precursors at th ...
... areas during development, so why isn’t lateral inhibition disrupted where these wavefronts contact non-neurogenic tissue? José María Frade, Saúl Ares and colleagues investigate this puzzle on p. 2321. The researchers show that Deltalike 1 (Dll1) is widely expressed by non-neurogenic precursors at th ...
What are Neurons
... Interneurons are responsible for communicating information between different neurons in the body. ...
... Interneurons are responsible for communicating information between different neurons in the body. ...
Chapter 10 Slides
... A series of periodic brain stimulations eventually elicits convulsions – the kindling phenomenon Neural changes are permanent Produced by stimulation distributed over time ...
... A series of periodic brain stimulations eventually elicits convulsions – the kindling phenomenon Neural changes are permanent Produced by stimulation distributed over time ...
Step Up To: Psychology
... • B) Enriched-environment rats showed more stress and aggression. • C) Enriched-environment rats were able to ...
... • B) Enriched-environment rats showed more stress and aggression. • C) Enriched-environment rats were able to ...