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- human genetics
- human genetics

... a. make a DNA fingerprint of every person's DNA. b. sequence all human DNA. c. cure human diseases. d. identify alleles in human DNA that are recessive. The human genome was sequenced a. by sequencing each gene on each chromosome, one at a time. b. using DNA fingerprinting. c. by looking for overlap ...
This examination paper consists of 4 pages
This examination paper consists of 4 pages

... Is divided into 24 chromosomes 17. Operons Occur only in bacterial genomes Contain more than one gene Contain more than one promoter Were discovered in the 19th century Contain long intergenic sequences ...
Chapter 12 Test Review
Chapter 12 Test Review

... Avery - Destroyed all cell products but DNA to find what genes are made of Hershey and Chase - Radioactive viruses used to show DNA is molecule of heredity Chargraff - Said the % of “A” = % of “T” and the % of “C” = % of “G” Rosalind Franklin - Discovered the shape of DNA through x-ray diffraction W ...
Chapter 12 Test Review
Chapter 12 Test Review

... Avery - Destroyed all cell products but DNA to find what genes are made of Hershey and Chase - Radioactive viruses used to show DNA is molecule of heredity Chargraff - Said the % of “A” = % of “T” and the % of “C” = % of “G” Rosalind Franklin - Discovered the shape of DNA through x-ray diffraction W ...
1 Biology 20 Protein Synthesis DNA: How is this linear information
1 Biology 20 Protein Synthesis DNA: How is this linear information

... If mutations occur in the gametes (sperm or ovum), then they can be transferred to offspring Gene mutation: Point mutations: 2 types of mutations: 1) Base substitution: a) could make no difference at all, why? GGC Æ GGU in mRNA; still codes for glycine b) could be: c) could be detrimental (useless p ...
Study Guide: Unit 1 Test 1. How would a DNA analyst`s job differ
Study Guide: Unit 1 Test 1. How would a DNA analyst`s job differ

Nutrition and Gene Expression Jan 29, 2015
Nutrition and Gene Expression Jan 29, 2015

... Problems in newborns from simple mutations are less common. The mutation rate is very low: the genes that a child inherits usually only differ at about 100 base pairs, from the genes in the parental DNA. Most of those sequence changes are harmless. ...
Name Class Date Skills Worksheet Look
Name Class Date Skills Worksheet Look

... In the spaces provided, write the letters of the two terms or phrases that are linked together by the term or phrase in the middle. The choices can be placed in any order. 15. ______ transformation ______ 16. ______ transformation not stopped by proteindestroying enzymes _______ 17. ______ five-carb ...
Chapter 13 - Angelfire
Chapter 13 - Angelfire

... – If a gene is marked, not passed on and that trait doesn’t show up, it may help identify the gene ...
DNA as Genetic Material
DNA as Genetic Material

... DNA polymerase can only add nucleotides to 3’ end of growing strand For each daughter DNA being synthesized there is leading strand and a lagging strand Leading strand grows from OOR in 3’ direction Lagging strand is filled in discontinuously on the 5’ end of the strand ...
ChapteR 16 The molecular basis of inheritance
ChapteR 16 The molecular basis of inheritance

... • Bacterial = one double-stranded, circular DNA molecule associated with a small amount of protein • Eukaryotic = linear DNA molecules associated with large amounts of protein ...
[ the current understanding of DNA has changed dramatically from
[ the current understanding of DNA has changed dramatically from

... inherit mtDNA from their maternal parent. In plants, cpDNA is transmitted maternally in most species, biparentally in some, and paternally in others. In many pine species, cpDNA is transmitted paternally and mtDNA maternally. In coast redwood, however, both cpDNA and mtDNA are inherited paternally. ...
Certificate of Analysis MicroSeq(R) 500 16S rDNA
Certificate of Analysis MicroSeq(R) 500 16S rDNA

... The combined forward and reverse sequencing accuracy is at least 99.5 % for the amplified product from E. coli genomic DNA. The combined forward and reverse sequencing clear read is at least 476 base pairs for the fragment sequenced using the amplified PCR product from E. coli genomic DNA ...
Lecture 10: Nucleic acids (DNA & RNA)
Lecture 10: Nucleic acids (DNA & RNA)

... viruses). 2) Ribonucleic acid (RNA): in some viruses, RNA serves as the genetic material.  Nucleic acids store and transmit genetic information ‫المعلومات الوراثية‬  Organisms inherit ‫ ترث‬DNA from their parents.  Each DNA molecule is very long and usually consists of hundreds to thousands of ge ...
Chapter 26: Biotechnology
Chapter 26: Biotechnology

... researchers know the sequence of three billion base pairs after 15 years of research. The two agencies that completed the task are The International Human Genome Sequencing Consortium and Celera Genomics, a private company. ...
Chapter 26: Biotechnology
Chapter 26: Biotechnology

... researchers know the sequence of three billion base pairs after 15 years of research. The two agencies that completed the task are The International Human Genome Sequencing Consortium and Celera Genomics, a private company. ...
NEW revision booklt - Eduspace
NEW revision booklt - Eduspace

... in nuclear DNA. 2 Highly repetitive sequences (satellite DNA) constitute 5–45% of the genome. The sequences are typically between 5 and 300 base pairs per repeat, and may be duplicated as many as 105 times per genome. Highly repetitive sequences were once classified as “junk DNA”, showing a degree o ...
Clinical Utility of Red Cell and Platelet Antigen Genotyping In
Clinical Utility of Red Cell and Platelet Antigen Genotyping In

... testing. Beware of variants! • Prenatal testing using fetal DNA in maternal plasma may help avoid invasive procedures • Red cell genotyping can be used to provide an expanded antigen profile on patients and for identifying antigen-negative donors. ...
Portfolio 4 Index
Portfolio 4 Index

... 16- The human genome consists of approximately how many DNA base pairs? a- 30,000 b- 3,000,000 c- 300,000,000 d- 3,000,000,000 17- The fraction of the human genome that actually codes for proteins is about a- 2% b- 20% c- 98% d- 100% 18- Cutting DNA into small pieces that can be sequenced is accompl ...
stranded DNA from genomic library
stranded DNA from genomic library

... • Combining nucleotide sequences from 2 sources to form a single DNA ...
HONORS BIOLOGY FINAL EXAM REVIEW PACKET AND FORMAT
HONORS BIOLOGY FINAL EXAM REVIEW PACKET AND FORMAT

... DNA REPLICATIONOCCURS AT REPLICATION FORKS, USES DNA POLYMERASE WHICH CAN ONLY WORK IN ONE DIRECTION, NITROGEN BASES ARE ADDED AT REPLICATION FORKS, ERRORS CAN BE CORRECTED USING DNA LIGASE AND PROOFREADER ENZYMES, THE DNA STRAND IS NOT DISSEMBLED WHEN CORRECTING FOR ERRORS MDOUBLE CHROMOSOMES ARE ...
DNA and the Chromosome
DNA and the Chromosome

... The next 6 slides will refer to material found in chapter 18. ...
zChap00_Front_140901
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Introduction to Next Generation Sequencing
Introduction to Next Generation Sequencing

... • Generate Read Enrichment Profile (e.g., Wald Lab tool) • Develop Null Model and Calculate Significantly Enriched Sites • High level analysis: compare to annotations, other data sets, etc ...
Document
Document

... • The Huntington's disease gene was localized to chromosome 4 by RFLP analysis. • One gene within the isolated chromosomal region that was abnormal in people with Huntington's disease had an unusual number of CAG codons at the 5' end of the coding region. Healthy individuals have about 11–25 of ...
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Cell-free fetal DNA

Cell-free fetal DNA (cffDNA) is fetal DNA circulating freely in the maternal blood stream. It can be sampled by venipuncture on the mother. Analysis of cffDNA provides a method of non-invasive prenatal diagnosis.cffDNA originates from the trophoblasts making up the placenta. It is estimated that 2-6% of the DNA in the maternal blood is fetal in origin. The fetal DNA is fragmented and makes its way into the maternal bloodstream via shedding of the placental microparticles into the maternal bloodstream (figure 1). Studies have shown that cffDNA can first be observed as early as 7 weeks gestation, and the amount of cffDNA increases as the pregnancy progresses. cffDNA diminishes quickly after the birth of the baby, so that it is no longer detectable in the maternal blood approximately 2 hours after birth. cffDNA is significantly smaller than the maternal DNA in the bloodstream, with fragments approximately 200bp in size. Many protocols to extract the fetal DNA from the maternal plasma use its size to distinguish it from the maternal DNA.Studies have looked at, and some even optimized, protocols for testing non-compatible RhD factors, sex determination for X-linked genetic disorders and testing for single gene disorders. Current studies are now looking at determining aneuploidies in the developing fetus. These protocols can be done earlier than the current prenatal testing methods, and have no risk of spontaneous abortion, unlike current prenatal testing methods. Non-invasive prenatal diagnosis (NIPD) has been implemented in the UK and parts of the US; it has clear benefits above the standard tests of chorionic villi sample (CVS) and amniocentesis which have procedure-related miscarriage risks of about 1 in 100 pregnancies and 1 in 200 pregnancies, respectively.As a method of prenatal diagnosis, cell-free fetal DNA techniques share the same ethical and practical issues, such as the possibility of prenatal sex discernment and sex selection.
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