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1 - Pdx
1 - Pdx

... correct errors that were made during replication. (5pts) Methylation occurs at GATC sites on the DNA. Since the methylation process takes some time to occur, the methyl-directed mismatch repair system is able to identify which strand is the newly replicated (unmethylated) strand of the DNA. Mismatch ...
Nucleic Acids - Rubin Gulaboski
Nucleic Acids - Rubin Gulaboski

... • Maintains correct genetic information • Two strands of DNA unwind ...
In Sickness and In Health
In Sickness and In Health

... Describe the function of the gene: Polycystin-1 is a glycoprotein. It may function as an integral membrane protein involved in cell-cell/matrix interactions, and may modulate intracellular calcium homoeostasis and other signal-transduction pathways. It plays a role in renal tubular development, and ...
Answers to Mastering Concepts Questions
Answers to Mastering Concepts Questions

... 7. Biologists once thought interphase is a time of cellular rest, but it is not. What happens during interphase? During interphase, the cell is not resting. Rather, the cell grows and produces molecules needed to build new organelles. In addition, during this stage, some organelles duplicate, the DN ...
Basic Bioinformatics
Basic Bioinformatics

... ACGT’s into knowledge of how the organism works is hard. Most of the work is on the computer, with key confirming experiments done in the “wet lab”. The sequence below contains a gene critical for life: the gene that initiates replication of the DNA. Can you spot it? We are now going to spend some t ...
Biotechnology
Biotechnology

... Molecular genetics- study of genes and how they are expressed Chromosome- part of cell nucleus that contains heredity information and promotes protein synthesis Gene- basic unit of heredity on a chromosome DNA- molecule in a chromosome that codes genetic information ...
Basic Bioinformatics - NIU Department of Biological Sciences
Basic Bioinformatics - NIU Department of Biological Sciences

... ACGT’s into knowledge of how the organism works is hard. Most of the work is on the computer, with key confirming experiments done in the “wet lab”. The sequence below contains a gene critical for life: the gene that initiates replication of the DNA. Can you spot it? We are now going to spend some t ...
Basic Bioinformatics
Basic Bioinformatics

... ACGT’s into knowledge of how the organism works is hard. Most of the work is on the computer, with key confirming experiments done in the “wet lab”. The sequence below contains a gene critical for life: the gene that initiates replication of the DNA. Can you spot it? We are now going to spend some t ...
Lecture 8. DNA AND THE LANGUAGE OF LIFE
Lecture 8. DNA AND THE LANGUAGE OF LIFE

... – He and other scientists, using this method, concluded the other amino acids represented by each codon. – There are 64 sequences (4³) with start and stop codes. ...
Pre-Lab: Molecular Biology
Pre-Lab: Molecular Biology

... The size of a piece of DNA can be analyzed by using a technique called gel electrophoresis. In this technique, a piece of DNA is cut into very specific sizes using enzymes called restriction enzymes. Restriction enzymes recognize specific sequences of DNA and will always cut in the same place. After ...
Notes Packet - Ms. Ottolini`s Biology Wiki!
Notes Packet - Ms. Ottolini`s Biology Wiki!

16792_bty100-4-2
16792_bty100-4-2

... A Gene is a segment of DNA and is located on the chromosome. Gene specifies the structure of particular protein that make up each cell. ...
Prokaryotes
Prokaryotes

... The first two domains are traditionally grouped as ‘prokaryotes’: - simpler internal structure than eukaryotic cells (no nucleus or other membrane enclosed organelles such as mitochondria) ...
Biotechnology
Biotechnology

... Molecular genetics- study of genes and how they are expressed Chromosome- part of cell nucleus that contains heredity information and promotes protein synthesis Gene- basic unit of heredity on a chromosome DNA- molecule in a chromosome that codes genetic information ...
Griffith`s Experiment
Griffith`s Experiment

... bacteria which killed the mice (pneumonia). The transformed bacteria were able to transmit the virulent property to offspring. DNA is the code that determines an organism’s traits. transformation: The ability of a bacteria to absorb DNA (transfer genes) from its surroundings. ...
2. In a double helix a region along one DNA strand
2. In a double helix a region along one DNA strand

... I. (40 pts total- 1 pt. per question) Multiple choice, fill in the blanks, matching. Choose the best answer. 1. Which molecule contains the most potential energy? a. b. c. d. e. ...
File
File

... The entire chain of shapes represent a chromosome - the individual shapes represent genes. The offspring inherits a pair of genes for each trait. When the genes are identical the offspring is called homozgous or purebred for that trait. When the genes are different, the offspring is called heterozyg ...
3D structures of RNA
3D structures of RNA

... structures as proteins, as well as simple double helix of type A.  The ability of being both informational and diverse in structure suggests that RNA was the prebiotic molecule that could function in both replication and catalysis (The RNA World Hypothesis).  In fact, some viruses encode their gen ...
Protein-coding genes in eukaryotic DNA
Protein-coding genes in eukaryotic DNA

... colleagues (2006) suggest that there are ~19,000 pseudogenes in the human genome, slightly fewer than the number of functional protein-coding genes. (11,000 non-processed, 8,000 processed [lack introns].) ...
DNA, Protein Synth, Mutations
DNA, Protein Synth, Mutations

... • sometimes mutations have no effect because they occur in a part of the DNA that is not used for protein synthesis or the mutated protein is not required for survival. These are known as NEUTRAL MUTATIONS and have they have NO EFFECT on the organism. • e.g. mutation in the gene that codes for fur c ...
Protein sequence database
Protein sequence database

... identification. Along with these advances has come a flood of genetic and biochemical data. But with the existence of these public data bases containing billions of data entries, the need for a robust, analytical approach in handling this data with respect to its biological significance ...
Mitochondrial DNA and Maximum Oxygen Consumption
Mitochondrial DNA and Maximum Oxygen Consumption

... training with mitochondrial DNA morphs detected by 22 restriction enzymes. The subjects were 46 North Americans who were sedentary at the time of the study. Of the variants identified, those subjects harboring a morph in the gene encoding Subunit 5 of NADH dehydrogenase demonstrated a significantly ...
Title goes here
Title goes here

... based on orthology, defined as bi-directional best BLAST hits, manually refined based on “Ortholog tables” and chromosomal clusters • Poorly documented, but seems to generate a lot less false positives than PathoLogic ...
Lesson 3 | DNA and Genetics
Lesson 3 | DNA and Genetics

... hemoglobin was genetically different from those who got the disease. This genetic change gave the patients’ red blood cells a sickle shape, rather than a normal disk shape. The change was also associated with a high risk of contracting a potentially fatal blood disease called sickle-cell disease. In ...
Chapter 10
Chapter 10

... Making Recombinant DNA 1. A restriction enzyme recognizes specific base sequences in DNA from two different sources 2. Restriction enzymes cut DNA into fragments with single-stranded tails (“sticky ends”) 3. DNA fragments from different sources are mixed together; matching sticky ends base-pair 4. ...
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Extrachromosomal DNA



Extrachromosomal DNA is any DNA that is found outside of the nucleus of a cell. It is also referred to as extranuclear DNA or cytoplasmic DNA. Most DNA in an individual genome is found in chromosomes but DNA found outside of the nucleus also serves important biological functions.In prokaryotes, nonviral extrachromosomal DNA is primarily found in plasmids whereas in eukaryotes extrachromosomal DNA is primarily found in organelles. Mitochondrial DNA is a main source of this extrachromosomal DNA in eukaryotes. Extrachromosomal DNA is often used in research of replication because it is easy to identify and isolate.Extrachromosomal DNA was found to be structurally different from nuclear DNA. Cytoplasmic DNA is less methylated than DNA found within the nucleus. It was also confirmed that the sequences of cytoplasmic DNA was different from nuclear DNA in the same organism, showing that cytoplasmic DNAs are not simply fragments of nuclear DNA.In addition to DNA found outside of the nucleus in cells, infection of viral genomes also provides an example of extrachromosomal DNA.
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