Erythroxylum coca
... m-opioid receptor KOs specifically lack responses to certain types of pain (next slide). 2. The a4b2 nicotinic receptor a4 or b2 nicotinic receptor knockouts: (1) respond less to nicotine in pain tests (next slide) (2) fail to self-administer nicotine (next slide). 3. The dopamine transporter Dopami ...
... m-opioid receptor KOs specifically lack responses to certain types of pain (next slide). 2. The a4b2 nicotinic receptor a4 or b2 nicotinic receptor knockouts: (1) respond less to nicotine in pain tests (next slide) (2) fail to self-administer nicotine (next slide). 3. The dopamine transporter Dopami ...
Lecture-13-2013-Bi
... m-opioid receptor KOs specifically lack responses to certain types of pain (next slide). 2. The a4b2 nicotinic receptor a4 or b2 nicotinic receptor knockouts: (1) respond less to nicotine in pain tests (next slide) (2) fail to self-administer nicotine (next slide). 3. The dopamine transporter Dopami ...
... m-opioid receptor KOs specifically lack responses to certain types of pain (next slide). 2. The a4b2 nicotinic receptor a4 or b2 nicotinic receptor knockouts: (1) respond less to nicotine in pain tests (next slide) (2) fail to self-administer nicotine (next slide). 3. The dopamine transporter Dopami ...
Adverse effects
... circulatory collapse. Headache, chills, and excessive sweating may also occur. Because of its cardiovascular effects, amphetamine should not be given to patients with cardiovascular disease or those receiving MAO inhibitors. Gastrointestinal system effects: anorexia, nausea, vomiting, abdominal cram ...
... circulatory collapse. Headache, chills, and excessive sweating may also occur. Because of its cardiovascular effects, amphetamine should not be given to patients with cardiovascular disease or those receiving MAO inhibitors. Gastrointestinal system effects: anorexia, nausea, vomiting, abdominal cram ...
amphetamine sulphate
... leading to a dental syndrome dubbed ‘meth mouth.’ Psychologically, regular and frequent speed use can cause a condition called Amphetamine Psychosis, typified by intense paranoia and anxiety. While the condition usually abates after the amphetamine use is discontinued, medical ...
... leading to a dental syndrome dubbed ‘meth mouth.’ Psychologically, regular and frequent speed use can cause a condition called Amphetamine Psychosis, typified by intense paranoia and anxiety. While the condition usually abates after the amphetamine use is discontinued, medical ...
Beyond the ABCs - Information for Professionals: Amphetamines
... Amphetamines are members of a class of drugs known as stimulants that includes caffeine, cocaine, and nicotine. Stimulants have the common property of increasing activity in the central nervous system (CNS). Some of these drugs are produced naturally by plants; others, like amphetamines, are the res ...
... Amphetamines are members of a class of drugs known as stimulants that includes caffeine, cocaine, and nicotine. Stimulants have the common property of increasing activity in the central nervous system (CNS). Some of these drugs are produced naturally by plants; others, like amphetamines, are the res ...
Stimulants - Littleton High School
... adrenaline, noradrenaline, and dopamine (these are all polar where amphetamine is nonpolar), it remains active in the body longer and effects can still be felt four to six hours after oral ingestion of a relatively ...
... adrenaline, noradrenaline, and dopamine (these are all polar where amphetamine is nonpolar), it remains active in the body longer and effects can still be felt four to six hours after oral ingestion of a relatively ...
principles of management of stimulant misuse
... enzymes Tolerance occurs partially due to transmitter depletion Neurotoxic to dopamine and serotonin neurons ...
... enzymes Tolerance occurs partially due to transmitter depletion Neurotoxic to dopamine and serotonin neurons ...
Testing For Amphetamines And Related Compounds
... 3. Assays that consist of dual assays for amphetamine and methamphetamine with low levels of cross-reactivity to OTC drugs. Up-to-date cross-reactivity data are typically listed in immunoassay package inserts or may be obtained from each manufacturer. Ideally, laboratories should perform cross-react ...
... 3. Assays that consist of dual assays for amphetamine and methamphetamine with low levels of cross-reactivity to OTC drugs. Up-to-date cross-reactivity data are typically listed in immunoassay package inserts or may be obtained from each manufacturer. Ideally, laboratories should perform cross-react ...
SE120144 - Sigma
... This kit avoids extraction of urine samples for measurement. It employs a d-amphetamine directed antiserum. Due to the proprietary method of orienting the antibody on the polystyrene microplate much higher sensitivity is achieved compared to passive adsorption. This allows an extremely small sample ...
... This kit avoids extraction of urine samples for measurement. It employs a d-amphetamine directed antiserum. Due to the proprietary method of orienting the antibody on the polystyrene microplate much higher sensitivity is achieved compared to passive adsorption. This allows an extremely small sample ...
Amphetamines - EDAS Essential Drugs and Alcohol Services
... With some people, and especially as the body's energy stores become run down, feelings of anxiety, irritability and restlessness are common. Taking a lot, especially over a few days, can produce panic and paranoia. This usually goes once the drug is eliminated from the body. The strong 'upper' effec ...
... With some people, and especially as the body's energy stores become run down, feelings of anxiety, irritability and restlessness are common. Taking a lot, especially over a few days, can produce panic and paranoia. This usually goes once the drug is eliminated from the body. The strong 'upper' effec ...
AMPHETAMINES RATIONALE FOR INCLUSION IN PA PROGRAM
... effectiveness of Vyvanse for treatment of obesity have not been established (6). ...
... effectiveness of Vyvanse for treatment of obesity have not been established (6). ...
Caffeine
... Agonist at presynaptic 5HT1 receptors in the midbrain and stimulates 5H2 receptors. Physical effects LSD can cause pupil dilatation, reduce or increase appetite, increased wakefulness, numbness, hypo or hyperthermia, elevated blood sugar, increase heart rate, jaw clenching. LSD is not considered add ...
... Agonist at presynaptic 5HT1 receptors in the midbrain and stimulates 5H2 receptors. Physical effects LSD can cause pupil dilatation, reduce or increase appetite, increased wakefulness, numbness, hypo or hyperthermia, elevated blood sugar, increase heart rate, jaw clenching. LSD is not considered add ...
Drug Facts Sheet Amphetamines
... larger percentage of the drug remains unchanged in the body, producing prolonged stimulant effects. Chronic abuse produces a psychosis that resembles schizophrenia and is characterized by: Paranoia, picking at the skin, preoccupation with one’s own thoughts, and auditory and visual hallucinations. V ...
... larger percentage of the drug remains unchanged in the body, producing prolonged stimulant effects. Chronic abuse produces a psychosis that resembles schizophrenia and is characterized by: Paranoia, picking at the skin, preoccupation with one’s own thoughts, and auditory and visual hallucinations. V ...
L5 ADHD
... Dopamine-dependent, mediated by the brain reward system Dose dependent increase in: -All behaviours resulting in fragmentation of behaviour swichtching – finally stereotypy Dopamin-dependent, mediated by striatum and N.accumbens ...
... Dopamine-dependent, mediated by the brain reward system Dose dependent increase in: -All behaviours resulting in fragmentation of behaviour swichtching – finally stereotypy Dopamin-dependent, mediated by striatum and N.accumbens ...
Benzedrine
... tolerance for them, can require increasingly large doses. • When the drugs wear off, a long period of sleep ensues, often followed by hunger and depression, which can lead to further use of amphetamines. • Amphetamine addiction has been common among such diverse groups as truck drivers, students, an ...
... tolerance for them, can require increasingly large doses. • When the drugs wear off, a long period of sleep ensues, often followed by hunger and depression, which can lead to further use of amphetamines. • Amphetamine addiction has been common among such diverse groups as truck drivers, students, an ...
LC-MS/MS Chiral Separation of âdâ and âlâ Enantiomers of
... AB SCIEX; Concord, Canada; 2Clinical Reference Laboratory, Kansas, USA Amphetamine and methamphetamine are psycho-stimulant drugs of the phenethylamine and amphetamine class of psychoactive drugs. Both compounds occur in two enantiomers, dextrorotary and levorotary. In the case of the methamphetamin ...
... AB SCIEX; Concord, Canada; 2Clinical Reference Laboratory, Kansas, USA Amphetamine and methamphetamine are psycho-stimulant drugs of the phenethylamine and amphetamine class of psychoactive drugs. Both compounds occur in two enantiomers, dextrorotary and levorotary. In the case of the methamphetamin ...
Amphetamines - MelsSchoolSite
... Long term, heavy amphetamine use can lead to insomnia and malnutrition. Psychological and emotional problems such as depression, paranoia and extreme aggressiveness can develop. In some cases, users may experience amphetamine psychosis - a psychological state, similar to schizophrenia - characterise ...
... Long term, heavy amphetamine use can lead to insomnia and malnutrition. Psychological and emotional problems such as depression, paranoia and extreme aggressiveness can develop. In some cases, users may experience amphetamine psychosis - a psychological state, similar to schizophrenia - characterise ...
Essay B5 Chem 151 Professor Whitesell Amphetamines Honestly
... treatment for attention deficit hyperactive disorder (ADHD). Adderall is a racemic mixture of dextroamphetamine and levoamphetamine (the D and L forms of the drug). Interestingly, it was found that dextroamphetamine form has a stronger effect on the CNS while the levoamphetamine form has a stronger ...
... treatment for attention deficit hyperactive disorder (ADHD). Adderall is a racemic mixture of dextroamphetamine and levoamphetamine (the D and L forms of the drug). Interestingly, it was found that dextroamphetamine form has a stronger effect on the CNS while the levoamphetamine form has a stronger ...
fatovich_amphetamine.aspx
... Professor Fatovich said there have been changing patterns of drug usage over time. In Australia the peak of heroin availability and use occurred around 1998–1999. This was followed by a shortage known as the “heroin drought” and a rise in amphetamine use, which peaked around 2005. This was followed ...
... Professor Fatovich said there have been changing patterns of drug usage over time. In Australia the peak of heroin availability and use occurred around 1998–1999. This was followed by a shortage known as the “heroin drought” and a rise in amphetamine use, which peaked around 2005. This was followed ...
Slide 1
... The Controlled Substances Act of 1970 placed all drugs into one of five schedules. Restricted the manufacture, distribution and use of amphetamines. Limited the medically-accepted uses to narcolepsy, attention deficit disorders, and short-term obesity. Can only be received by a written prescripti ...
... The Controlled Substances Act of 1970 placed all drugs into one of five schedules. Restricted the manufacture, distribution and use of amphetamines. Limited the medically-accepted uses to narcolepsy, attention deficit disorders, and short-term obesity. Can only be received by a written prescripti ...
Stimulant Amphetamine use in high intensity exercise athletes
... No link between socio-demographic characteristics or level of education amongst users. Increased incidence of combined amphetamine and illicit drug use … such as steroids. Implications for extended drug action in the exercised ...
... No link between socio-demographic characteristics or level of education amongst users. Increased incidence of combined amphetamine and illicit drug use … such as steroids. Implications for extended drug action in the exercised ...
ADDERALL (the study drug)
... concentration task not on Adderall. The yellow and green colors show significant decreased activity in the top surface of the Brain. ...
... concentration task not on Adderall. The yellow and green colors show significant decreased activity in the top surface of the Brain. ...
Amphetamine
Amphetamine (contracted from alpha‑methylphenethylamine) is a potent central nervous system (CNS) stimulant that is used in the treatment of attention deficit hyperactivity disorder (ADHD), narcolepsy, and obesity. Amphetamine was discovered in 1887 and exists as two enantiomers: levoamphetamine and dextroamphetamine. Amphetamine properly refers to a specific chemical, the racemic free base, which is equal parts of the two enantiomers, levoamphetamine and dextroamphetamine, in their pure amine forms. However, the term is frequently used informally to refer to any combination of the enantiomers, or to either of them alone. Historically, it has been used to treat nasal congestion, depression, and obesity. Amphetamine is also used as a performance and cognitive enhancer, and recreationally as an aphrodisiac and euphoriant. It is a prescription medication in many countries, and unauthorized possession and distribution of amphetamine are often tightly controlled due to the significant health risks associated with recreational use.The first pharmaceutical amphetamine was Benzedrine, a brand of inhalers used to treat a variety of conditions. Currently, pharmaceutical amphetamine is prescribed as racemic amphetamine, Adderall, dextroamphetamine, or the inactive prodrug lisdexamfetamine. Amphetamine, through activation of a trace amine receptor, increases biogenic amine and excitatory neurotransmitter activity in the brain, with its most pronounced effects targeting the catecholamine neurotransmitters norepinephrine and dopamine. At therapeutic doses, this causes emotional and cognitive effects such as euphoria, change in libido, increased wakefulness, and improved cognitive control. It induces physical effects such as decreased reaction time, fatigue resistance, and increased muscle strength.Much larger doses of amphetamine may impair cognitive function and induce rapid muscle breakdown. Drug addiction is a serious risk with large recreational doses, but rarely arises from medical use. Very high doses can result in psychosis (e.g., delusions and paranoia) which rarely occurs at therapeutic doses even during long-term use. Recreational doses are generally much larger than prescribed therapeutic doses and carry a far greater risk of serious side effects.Amphetamine belongs to the phenethylamine class. It is also the parent compound of its own structural class, the substituted amphetamines, which includes prominent substances such as bupropion, cathinone, MDMA (ecstasy), and methamphetamine. As a member of the phenethylamine class, amphetamine is also chemically related to the naturally occurring trace amine neuromodulators, specifically phenethylamine and N-methylphenethylamine, both of which are produced within the human body. Phenethylamine is the parent compound of amphetamine, while N-methylphenethylamine is a constitutional isomer that differs only in the placement of the methyl group.