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A Serine/Proline-Rich Protein Is Fused To HRX in t(4
A Serine/Proline-Rich Protein Is Fused To HRX in t(4

... More specific localization was obtained by fluorescence in situ hybridization to human metaphase chromosomes. Two probes (2 and 3; Fig 2, B and C) were hybridized to the chromosomes simultaneously; 11 of 31 metaphases scored had specific signal on at least one chromosome 4 homolog. Two of these 1 1 ...
Evolution of genes, evolution of species: the case of aminoacyl
Evolution of genes, evolution of species: the case of aminoacyl

... Doolittle and Brown (1994) called ‘‘the Woesian revolution,’’ was probably the delineation of the three kingdoms of life (Eukaryotes, Eubacteria, and Archaebacteria) based on the analysis of ribosomal RNA sequences (Fox et al. 1977; Woese and Fox 1977). Later, Iwabe et al. (1989) and Gogarten et al. ...
1548 Tn Gene Is Borne by Composite Transposon Aminoglycoside
1548 Tn Gene Is Borne by Composite Transposon Aminoglycoside

... of ca. 90 kb which also encodes the extended-spectrum ␤-lactamase CTX-M-3. Thirty-four enterobacteria from various countries that were likely to produce a CTX-M enzyme since they were more resistant to cefotaxime than to ceftazidime were studied. The armA gene was detected in 12 clinical isolates of ...
Mutation Screening of the EXT Genes in Patients with Hereditary
Mutation Screening of the EXT Genes in Patients with Hereditary

... 3 out of 9 affected members; the frequencies of these alleles (T and G at position 966) were 0.833 and 0.167, respectively. However, results obtained from healthy (non-HME) individuals were 0.9 and 0.1, respectively. In other words, the frequency of G allele was higher in HME versus non-HME individu ...
From Genes to Proteins
From Genes to Proteins

... base-pairs with another nucleic acid. transcription A gene’s instructions for making a protein are coded in the translation sequence of nucleotides in the gene. The instructions for making a gene expression protein are transferred from a gene to an RNA molecule in a process RNA polymerase called tra ...
Phytozome Tutorial from David Goodstein
Phytozome Tutorial from David Goodstein

... genes for 18 plant genomes (in version 5). Sequence similarity (BLAST/BLAT) and keywordbased searching can help you pinpoint genes and gene families of interest. You can navigate the evolutionary history of each gene family, and identify closely related families (via shared functional annotation or ...
Synthetic Biology and the CBD
Synthetic Biology and the CBD

... DNA mean that ‘digital’ biopiracy is now possible, circumventing rules on access and benefit sharing. Parties at COP13 should agree to a two-step process where the issue of digital sequences can be quickly considered at a technical level by the AHTEG and then brought to the Parties to the Nagoya Pro ...
Lac A
Lac A

... 2In humans trisomy of chromosome 21 is responsible of the Down syndrome. - which gametes originated an affected person? - draw a scheme of the meiotic stages that can give rise to the mutated gamete and indicate the name of this process. - Chromosomes are distributed to gametes incorrectly - The ga ...
Amplified fragment length polymorphism (AFLP)
Amplified fragment length polymorphism (AFLP)

... mechanisms (Martin et al., 1993; Tanksley et al., 1995). Restriction fragment length polymorphism (RFLP) markers have been routinely previously used for agronomic crops linkage analysis and genomes mapping (Tanksley et al., 1989). However, construction of RFLP maps has been very difficult due to the ...
PowerPoint - Beef Improvement Federation
PowerPoint - Beef Improvement Federation

... Animal Biotechnology and Genomics Education ...
LOSS OF HETEROZYGOSITY DUE TO SHORT-TRACT AND LONG-TRACT SACCHAROMYCES CEREVISIAE Thomas Coates
LOSS OF HETEROZYGOSITY DUE TO SHORT-TRACT AND LONG-TRACT SACCHAROMYCES CEREVISIAE Thomas Coates

Multiple Mechanisms Contribute to Lateral Transfer of an
Multiple Mechanisms Contribute to Lateral Transfer of an

... The oriV was predicted based on sequence homology to other annotated or predicted oriVs and by performing GC skew analysis (Grigoriev 1998). While calculating the GC skew, the ratio of (G-C) to (G +C) was calculated per each window of equal length split over the total sequence of pPDL2. The GC skew ...
Guidelines for interpretation of 16S rRNA gene sequence
Guidelines for interpretation of 16S rRNA gene sequence

... characterization were given for this strain. Therefore, the true identity of this strain is difficult to ascertain. In the present study and a previous one (Woo et al., 2007), we used .3, 2–3 and ,2 % differences between the most representative 16S rRNA gene sequence of species obtained from GenBank ...
Chromatin Domain Boundaries: Defining the Functional Domains in
Chromatin Domain Boundaries: Defining the Functional Domains in

... associated with the protein of interest. ChIP can be combined with micro array to identify such sites on a genome level a technique termed ChIP-on-chip [26]. In this method ChIP is performed as usual and the DNA is analyzed using a chip of whole genome tiling array. This technique can be used to ide ...
The Evolution of tRNA-Leu Genes in Animal
The Evolution of tRNA-Leu Genes in Animal

... amino acid. In the standard genetic code, Arginine also has a four- and a two-codon family. However, in mitochondria, the two codon family is either used as stop codons or reassigned to form a four codon Serine family. The L and L2 genes on the mitochondrial genome of any one species must, by defini ...
SEC62 Encodes a Putative Membrane Protein Required for Protein
SEC62 Encodes a Putative Membrane Protein Required for Protein

... disruption allele (strain RPD99 and RPD95) were also hybridized to the 32p-labeled Eco RVc-CIa I fragment of pSEC6207 at high stringency as described above. In these cases, hybridization to the fragment bearing the wild-type SEC62 allele always decreased in intensity by ,x,2 fold (relative to W303-L ...
DNA and the Book of Mormon: A Phylogenetic Perspective
DNA and the Book of Mormon: A Phylogenetic Perspective

... can claim to do scientific research, it is widely accepted within the scientific community that the touchstone of quality in a research program is the ability to obtain external funding from a nationally peer-reviewed granting agency and to publish the results in a reputable scientific journal. To b ...
CS790 – Introduction to Bioinformatics
CS790 – Introduction to Bioinformatics

... GCG-TIntro to Bioinformatics – Sequence Alignment ...
University of Bucharest, Faculty of Biology, Molecular Biology Center
University of Bucharest, Faculty of Biology, Molecular Biology Center

... Figure 2. Electrophoresis pattern of amplified fragments after digestion with Ava I enzyme. Lines 1-7, two fragments of 108 and 28bp characteristic for homozygous cattle (BLAD); lines 1-7, three fragments of 51, 36 and 21bp characteristic for homozygous cattle (DUMPS). Line 8, molecular size marker ...
Replicational and transcriptional selection on codon usage in
Replicational and transcriptional selection on codon usage in

... level of replication. An organism that can replicate more quickly could have a selective advantage over one whose replication is retarded. It was pointed out by Fraser et al. (7) that approximately two-thirds of the genes on the B. burgdorferi genome were transcribed away from the origin of replicat ...
Query Results
Query Results

... Step 4: The user can choose to map the experimental tags against a subset of genomic tags upon a large amount of different features. For details see the help links or: Malig, R., Varela, C., Agosin, E. and Melo, F. (2006) Accurate and unambiguous tag-to-gene mapping in SAGE by a hierarchical gene a ...
Ecological Risks of Gene Drive Technologies
Ecological Risks of Gene Drive Technologies

... Some gene drive mechanisms are ‘global’, designed to spread throughout a population from very low initial numbers, and hence potentially to all populations, and even to closely related species. With global gene drives there may be no such thing as a confined field trial. Other ‘local’ gene drives ca ...
Ionic distribution around simple DNA models. I
Ionic distribution around simple DNA models. I

... and ions seems to be the natural choice ~for a review on full-atom DNA molecular dynamics simulations see Ref. 18!. Unfortunately, this approach suffers from various inconveniences. The huge computational demand of the simulations with explicit water coerces its application to small systems with few ...
Two Cyp19 (P450 Aromatase) Genes on Duplicated Zebrafish
Two Cyp19 (P450 Aromatase) Genes on Duplicated Zebrafish

... branched as expected from the known evolutionary relationships of the species. All fish Cyp19 genes clustered together on the same branch, suggesting that they were all orthologs of the single mammalian Cyp19 gene. The fish branch, however, bifurcated into two subbranches with a high bootstrap value ...
Direct Deletion Analysis in Two Duchenne Muscular Dystrophy
Direct Deletion Analysis in Two Duchenne Muscular Dystrophy

... results confirm that only the paternal allele (2 nucleotides heavier than the maternal) is present in the proband. Case 2: This case is a clear example of how an indirect analysis (using STRs) becomes a direct one. A deletion of two of the six loci that were studied for this family was identified in ...
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Genomics

Genomics is a discipline in genetics that applies recombinant DNA, DNA sequencing methods, and bioinformatics to sequence, assemble, and analyze the function and structure of genomes (the complete set of DNA within a single cell of an organism). Advances in genomics have triggered a revolution in discovery-based research to understand even the most complex biological systems such as the brain. The field includes efforts to determine the entire DNA sequence of organisms and fine-scale genetic mapping. The field also includes studies of intragenomic phenomena such as heterosis, epistasis, pleiotropy and other interactions between loci and alleles within the genome. In contrast, the investigation of the roles and functions of single genes is a primary focus of molecular biology or genetics and is a common topic of modern medical and biological research. Research of single genes does not fall into the definition of genomics unless the aim of this genetic, pathway, and functional information analysis is to elucidate its effect on, place in, and response to the entire genome's networks.
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