Genomic scans for selective sweeps using SNP data
... Access the most recent version at doi:10.1101/gr.4252305 ...
... Access the most recent version at doi:10.1101/gr.4252305 ...
Sequence of the Tribolium castaneum Homeotic Complex
... here confirm previous analyses and are included for completeness. Tclab is located at the 3⬘ end of the HOMC. The 13-kb transcription unit is composed of two exons (658 and 816 bp) separated by an 11.6-kb intron located 125 bp upstream of the homeobox. The mxp gene, located 13.8 kb upstream of Tclab ...
... here confirm previous analyses and are included for completeness. Tclab is located at the 3⬘ end of the HOMC. The 13-kb transcription unit is composed of two exons (658 and 816 bp) separated by an 11.6-kb intron located 125 bp upstream of the homeobox. The mxp gene, located 13.8 kb upstream of Tclab ...
Insertion (sufB) in the anticodon loop or base substitution (sufC) in
... flanking sequence similarity between the two species is about 83%, the similarity of the 3' flanking sequence is only 42%. Still, the Salmonella tRNA**"^ gene has a rho-independent transcriptional termination signal similar to the one present in E.coll tRNAPro2 gene. INTRODUCTION Nontriplet reading ...
... flanking sequence similarity between the two species is about 83%, the similarity of the 3' flanking sequence is only 42%. Still, the Salmonella tRNA**"^ gene has a rho-independent transcriptional termination signal similar to the one present in E.coll tRNAPro2 gene. INTRODUCTION Nontriplet reading ...
The Two Faces of Higher Eukaryotic DNA Replication Origins
... must emanate bidirectionally from a site that is no larger than 450 nucleotides. In this review, we hope to show that these apparently conflicting data are not necessarily irreconcilable. Instead, the two sets of data may illuminate two different faces of the higher eukaryotic chromosomal replicatio ...
... must emanate bidirectionally from a site that is no larger than 450 nucleotides. In this review, we hope to show that these apparently conflicting data are not necessarily irreconcilable. Instead, the two sets of data may illuminate two different faces of the higher eukaryotic chromosomal replicatio ...
Supplementary Figure Legends (doc 52K)
... profiles of bacterial PCR products from separated (a) [13C]-phenanthrene fractions aligned to equivalent [12C]-phenanthrene fractions, (b) [13C]naphthalene fractions aligned to equivalent [12C]-naphthalene fractions, and (c) [13C]-hexadecane fractions aligned to equivalent [12C]hexadecane fractions, ...
... profiles of bacterial PCR products from separated (a) [13C]-phenanthrene fractions aligned to equivalent [12C]-phenanthrene fractions, (b) [13C]naphthalene fractions aligned to equivalent [12C]-naphthalene fractions, and (c) [13C]-hexadecane fractions aligned to equivalent [12C]hexadecane fractions, ...
Brand, Veronica - Degenerate Primer Design using Computational Tools
... degenerate primers targeting 16S rRNA, as one might do for studying microbial diversity. This may not be a major limitation since 16S rRNA genes are generally more highly conserved than proteins; sequences may be sufficiently related to design primers manually. More significant limitations include t ...
... degenerate primers targeting 16S rRNA, as one might do for studying microbial diversity. This may not be a major limitation since 16S rRNA genes are generally more highly conserved than proteins; sequences may be sufficiently related to design primers manually. More significant limitations include t ...
Discovery and characterization of chromatin states for Please share
... 2.7% genome-wide (P<10−200, for all states). These states accounted for 59% of all RefSeq TSS while covering only 1.3% of genome. These states all had in common a high frequency of H3K4me3, but differed in terms of other associated marks, primarily H3K79me2/3, H4K20me1, H3K4me1/2, and H3K9me1, and t ...
... 2.7% genome-wide (P<10−200, for all states). These states accounted for 59% of all RefSeq TSS while covering only 1.3% of genome. These states all had in common a high frequency of H3K4me3, but differed in terms of other associated marks, primarily H3K79me2/3, H4K20me1, H3K4me1/2, and H3K9me1, and t ...
controversy and its implications Genetic hitchhiking versus
... distinguishing BGS and hitchhiking was a major activity in those years (until about 2000). An important question has been whether BGS alone can account for the patterns of variation we observe, or whether positive selection also needs to be invoked. Although numerous attempts have been made, the con ...
... distinguishing BGS and hitchhiking was a major activity in those years (until about 2000). An important question has been whether BGS alone can account for the patterns of variation we observe, or whether positive selection also needs to be invoked. Although numerous attempts have been made, the con ...
SNP
... alleles (0.1% of total SNPs is tri-allelic markers in TSC data). SNPs has lower mutation rate than do repeat sequences, but not as informative as microsatellite markers. detection methods for SNPs are potentially more suitable for genetic screening in automated and large-scale. the SNPs are likely b ...
... alleles (0.1% of total SNPs is tri-allelic markers in TSC data). SNPs has lower mutation rate than do repeat sequences, but not as informative as microsatellite markers. detection methods for SNPs are potentially more suitable for genetic screening in automated and large-scale. the SNPs are likely b ...
Inherited Representations are Read in
... input side, incoming bees are disposed to produce dances that do correlate with the location of nectar. When an incoming bee produces a dance of type D, of three waggles in the vertical direction, there is a good chance of nectar 250 metres away in the direction of the sun (Condition (b)). Furthermo ...
... input side, incoming bees are disposed to produce dances that do correlate with the location of nectar. When an incoming bee produces a dance of type D, of three waggles in the vertical direction, there is a good chance of nectar 250 metres away in the direction of the sun (Condition (b)). Furthermo ...
Major City Chiefs Position Paper on Sworn vs
... Hybrid Models – The Committee recommends that hybrid units of civilian and sworn personnel, if implemented, are considered carefully. o A hybrid model, as long as all staff meet the same scientific/technical standards, can be beneficial due to the diversity of experiences. o This model also has the ...
... Hybrid Models – The Committee recommends that hybrid units of civilian and sworn personnel, if implemented, are considered carefully. o A hybrid model, as long as all staff meet the same scientific/technical standards, can be beneficial due to the diversity of experiences. o This model also has the ...
Cutting Edge: DNA Polymerases and Are Dispensable for Ig Gene
... whose contribution is crucial to diversify the third complementarity-determining region of Ig and TCR genes during V(D)J rearrangement; 2) despite a ubiquitous expression, a higher level of transcription in lymphoid tissues, in particular B cells from tonsils, but also, and obviously not in favor of ...
... whose contribution is crucial to diversify the third complementarity-determining region of Ig and TCR genes during V(D)J rearrangement; 2) despite a ubiquitous expression, a higher level of transcription in lymphoid tissues, in particular B cells from tonsils, but also, and obviously not in favor of ...
Influence of industrial contamination on mobile genetic elements
... extension. To ensure specificity for each reaction, multiple analyses were conducted. A melt curve was analyzed after each qPCR run, while randomly selected samples were run on a 1% agarose gel in 10 TBE solution for 30 min at 80 V to check for the presence of a single band of the appropriate size ...
... extension. To ensure specificity for each reaction, multiple analyses were conducted. A melt curve was analyzed after each qPCR run, while randomly selected samples were run on a 1% agarose gel in 10 TBE solution for 30 min at 80 V to check for the presence of a single band of the appropriate size ...
Genomic surveys and expression analysis of bZIP gene family in
... genes) and b (including 15 genes) were the most prevalent. The pattern a had an intron in P2 behind the position −22 (R) within the basic region, whereas the pattern b had an intron in P0 before the position −5 (A) within the hinge region. The pattern c (including 7 genes) had two introns (each in P ...
... genes) and b (including 15 genes) were the most prevalent. The pattern a had an intron in P2 behind the position −22 (R) within the basic region, whereas the pattern b had an intron in P0 before the position −5 (A) within the hinge region. The pattern c (including 7 genes) had two introns (each in P ...
Using Ontology Graphs to Understand Annotations and Reason about Them
... that the allele annotations segregate in separate ontology branches. Only the allelic composition Arxtm1Kki/Y highlevel phenotypes correspond to nervous system and reproductive system phenotypes, while only the allelic composition Arxtm1Pgr/Y corresponds to homeostasis/metabolism and growth/size phe ...
... that the allele annotations segregate in separate ontology branches. Only the allelic composition Arxtm1Kki/Y highlevel phenotypes correspond to nervous system and reproductive system phenotypes, while only the allelic composition Arxtm1Pgr/Y corresponds to homeostasis/metabolism and growth/size phe ...
Genetic dissection of Helicobacter pylori AddAB role in homologous
... modeling the AddAB complex structure, we investigated using a genetics approach the in vivo roles of the H. pylori addA and addB gene products during recombinational repair, exogenous DNA incorporation and intrachromosomal recombination. Furthermore, using double or triple mutants in HR genes, we de ...
... modeling the AddAB complex structure, we investigated using a genetics approach the in vivo roles of the H. pylori addA and addB gene products during recombinational repair, exogenous DNA incorporation and intrachromosomal recombination. Furthermore, using double or triple mutants in HR genes, we de ...
Mutation, Mutagens, and DNA Repair
... the integrity of bacterial DNA is confirmed by the observation that dam- strains of E. coli have increased rates of spontaneous mutation. The mismatch repair system can act at a distance - in other words, a mismatch can be repaired even though the nearest hemimethylated site is 1000 bp away. Repair ...
... the integrity of bacterial DNA is confirmed by the observation that dam- strains of E. coli have increased rates of spontaneous mutation. The mismatch repair system can act at a distance - in other words, a mismatch can be repaired even though the nearest hemimethylated site is 1000 bp away. Repair ...
Driscoll Katee Driscoll Dr. Ely Genetics October 20, 2013 Effects of
... optimal prediction model, which relied on the method of splitting the data (using some of the data as a training set to predict the HTT CAG repeat lengths for the remaining samples that comprised the other set) (Lee et al. 2013). When the model was run, it was found to predict CAG repeat lengths wit ...
... optimal prediction model, which relied on the method of splitting the data (using some of the data as a training set to predict the HTT CAG repeat lengths for the remaining samples that comprised the other set) (Lee et al. 2013). When the model was run, it was found to predict CAG repeat lengths wit ...
PDF - Molecular Cytogenetics
... Molecular cytogenetic investigation has confirmed that the translocation present in the proband and his sister was maternally inherited. The coincident and unexpected finding of mosaicism of X-chromosome in the aunt (C3) and grandmother (G1) is intriguing. Chromosomal mosaicisms are not heritable si ...
... Molecular cytogenetic investigation has confirmed that the translocation present in the proband and his sister was maternally inherited. The coincident and unexpected finding of mosaicism of X-chromosome in the aunt (C3) and grandmother (G1) is intriguing. Chromosomal mosaicisms are not heritable si ...
Blue cone monochromacy: Causative mutations and associated
... (BCM), and to determine the underlying molecular genetic basis of disease. Methods: Affected members of three British families with BCM were examined clinically and underwent detailed electrophysiological and psychophysical testing. Blood samples were taken for DNA extraction. Molecular analysis inv ...
... (BCM), and to determine the underlying molecular genetic basis of disease. Methods: Affected members of three British families with BCM were examined clinically and underwent detailed electrophysiological and psychophysical testing. Blood samples were taken for DNA extraction. Molecular analysis inv ...
Differential roles of TGIF family genes in mammalian reproduction Open Access
... Human TGIFLX and its orthologue, Tex1 in the mouse, are X-linked genes that are only expressed in the adult testis. TGIF2 arose from TGIF1 by duplication, whereas TGIFLX arose by retrotransposition to the X-chromosome. These genes have not been characterised in any non-eutherian mammals. We therefor ...
... Human TGIFLX and its orthologue, Tex1 in the mouse, are X-linked genes that are only expressed in the adult testis. TGIF2 arose from TGIF1 by duplication, whereas TGIFLX arose by retrotransposition to the X-chromosome. These genes have not been characterised in any non-eutherian mammals. We therefor ...
B. thuringiensis kurstaki
... Therefore, under these conditions the toxin will be produced in high quantities. Many crops might be attacked by different insect species, therefore, it would be advantageous if we could create microbial insecticides with broad spectrum of target insects. This could be done by; Transferring a gene ...
... Therefore, under these conditions the toxin will be produced in high quantities. Many crops might be attacked by different insect species, therefore, it would be advantageous if we could create microbial insecticides with broad spectrum of target insects. This could be done by; Transferring a gene ...
rolduc meeting. feel connected!
... and physics in Frankfurt am Main from 1962 to 1964. At the university of Tübingen she received her diploma in biochemistry in 1968 and her PhD (genetics) in 1973. She worked as a postdoc subsequently in the laboratories of Prof. Dr. Walter Gehring at the Biozentrum in Basel (Switzerland) and of Prof ...
... and physics in Frankfurt am Main from 1962 to 1964. At the university of Tübingen she received her diploma in biochemistry in 1968 and her PhD (genetics) in 1973. She worked as a postdoc subsequently in the laboratories of Prof. Dr. Walter Gehring at the Biozentrum in Basel (Switzerland) and of Prof ...