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arXiv:0708.2724v1 [cond-mat.other] 20 Aug 2007
... With the continued improvement of sequencing technologies, the prospect of genome-based medicine is now at the forefront of scientific research. To realize this potential, however, we need a revolutionary sequencing method for the cost-effective and rapid interrogation of individual genomes. This ca ...
... With the continued improvement of sequencing technologies, the prospect of genome-based medicine is now at the forefront of scientific research. To realize this potential, however, we need a revolutionary sequencing method for the cost-effective and rapid interrogation of individual genomes. This ca ...
β-Scruin, a homologue of the actin crosslinking protein scruin, is
... Fig. 1. An alignment between the predicted amino acid sequence of β-scruin (top) and α-scruin (bottom) generated by ALIGN using the default settings. The cDNA sequence has been submitted to the EMBL Sequence Database, accession number Z47541. Exact identities between the two sequences are indicated ...
... Fig. 1. An alignment between the predicted amino acid sequence of β-scruin (top) and α-scruin (bottom) generated by ALIGN using the default settings. The cDNA sequence has been submitted to the EMBL Sequence Database, accession number Z47541. Exact identities between the two sequences are indicated ...
Phylogenetic Motif Detection by Expectation
... sequences as a mixture of multinomial models for motif and background and uses an Expectation-Maximization (EM) algorithm to estimate the parameters. Because functional binding sites are evolutionarily constrained, their preferential conservation relative to background sequence has proven a useful ...
... sequences as a mixture of multinomial models for motif and background and uses an Expectation-Maximization (EM) algorithm to estimate the parameters. Because functional binding sites are evolutionarily constrained, their preferential conservation relative to background sequence has proven a useful ...
RPG-Consent-aCGH NGS for aneuploidy_2015_Final
... methods being used clinically to perform PGS in human preimplantation embryos. Nevertheless, NGS is a new experimental technique and as such, the exact accuracy and potential limitations of the technique have not yet been conclusively determined. NGS is being introduced into clinical practice since ...
... methods being used clinically to perform PGS in human preimplantation embryos. Nevertheless, NGS is a new experimental technique and as such, the exact accuracy and potential limitations of the technique have not yet been conclusively determined. NGS is being introduced into clinical practice since ...
Plant Functional Genomics Plant Functional Genomics
... Large genomic DNA insert-containing libraries are essential for physical mapping, positional cloning, and genome sequencing of complex genomes. There are two principal large insert cloning systems that are constructed as yeast or bacterial artificial chromosomes (YACs and BACs, respectively). The YA ...
... Large genomic DNA insert-containing libraries are essential for physical mapping, positional cloning, and genome sequencing of complex genomes. There are two principal large insert cloning systems that are constructed as yeast or bacterial artificial chromosomes (YACs and BACs, respectively). The YA ...
Polycomb Group silencers collaborate with Notch pathway to cause
... HpaII will not cut at its recognition sequence if it contains a methylated cytosine (mCCGG), both MspI and HpaII digestion will be blocked if both cytosines are methylated (mCmCGG). ...
... HpaII will not cut at its recognition sequence if it contains a methylated cytosine (mCCGG), both MspI and HpaII digestion will be blocked if both cytosines are methylated (mCmCGG). ...
Isolation and characterization of Viviparous
... and Vp-1D genes (Table 1). Another three pairs of genome-specific primers, RTVp-1AF/R, RTVp-1BF/R, and RTVp-1DF/R (Table 1), were designed to perform RT-PCR of the Vp-1A, Vp-1B, and Vp-1D genes, respectively. The wheat ACTIN gene was included as an internal control in each reaction in order to norma ...
... and Vp-1D genes (Table 1). Another three pairs of genome-specific primers, RTVp-1AF/R, RTVp-1BF/R, and RTVp-1DF/R (Table 1), were designed to perform RT-PCR of the Vp-1A, Vp-1B, and Vp-1D genes, respectively. The wheat ACTIN gene was included as an internal control in each reaction in order to norma ...
Whole Exome Re-Sequencing Implicates CCDC38 and
... Funding: The whole exome re-sequencing of the 100 resistant smokers and the secondary control set (TwinsUK) was funded by Pfizer Ltd. MDT holds a Medical Research Council Senior Clinical Fellowship (G0902313). This report presents independent research funded partially by the National Institute for H ...
... Funding: The whole exome re-sequencing of the 100 resistant smokers and the secondary control set (TwinsUK) was funded by Pfizer Ltd. MDT holds a Medical Research Council Senior Clinical Fellowship (G0902313). This report presents independent research funded partially by the National Institute for H ...
The Structures of DNA and RNA
... of intra-strand base pairing, RNA exhibits extensive double-helical character and is capable of folding into a wealth of diverse tertiary structures. These structures are full of surprises, such as non-classical base pairs, base-backbone interactions, and knot-like configurations. Most remarkable of ...
... of intra-strand base pairing, RNA exhibits extensive double-helical character and is capable of folding into a wealth of diverse tertiary structures. These structures are full of surprises, such as non-classical base pairs, base-backbone interactions, and knot-like configurations. Most remarkable of ...
DROSOPHILA MELANOGASTER - THE MODEL ORGANISM OF
... between homologous chromosomes and the chromosomal basis of sex determination (Sturtevant, 1965). But beyond these theoretical contributions, the genetic tools evolved from these studies have placed Drosophila in its unparalleled position in terms of understanding gene/protein function. In particula ...
... between homologous chromosomes and the chromosomal basis of sex determination (Sturtevant, 1965). But beyond these theoretical contributions, the genetic tools evolved from these studies have placed Drosophila in its unparalleled position in terms of understanding gene/protein function. In particula ...
Evidence, Mechanisms and Models for the Inheritance of Acquired
... addition to the templating activity associated with the multiplication of centrioles, features showing architectural continuity have been found in neuroblastoma and 3T3 cells in vitro (Albrecht-Buehler, 1977; Solomon, 1979), and caterpillar epidermis cells in vivo (Locke, 1988). We have described th ...
... addition to the templating activity associated with the multiplication of centrioles, features showing architectural continuity have been found in neuroblastoma and 3T3 cells in vitro (Albrecht-Buehler, 1977; Solomon, 1979), and caterpillar epidermis cells in vivo (Locke, 1988). We have described th ...
"PCR-based Species Identification and Gene Tagging"
... maize leaf _Bots infected leaf pt3 infected leaf pt1 P sorghi pt3 P sorghi pt1 Marker ...
... maize leaf _Bots infected leaf pt3 infected leaf pt1 P sorghi pt3 P sorghi pt1 Marker ...
WORKING WTH THE FIGURES
... The two loci P and Bz are normally 36 m.u. apart on the same arm of a certain plant chromosome. A paracentric inversion spans about one-fourth of this region but does not include either of the loci. What approximate recombinant frequency between P and Bz would you predict in plants that are a. heter ...
... The two loci P and Bz are normally 36 m.u. apart on the same arm of a certain plant chromosome. A paracentric inversion spans about one-fourth of this region but does not include either of the loci. What approximate recombinant frequency between P and Bz would you predict in plants that are a. heter ...
XSL Formatter - H:\XML
... instructions are provided for several common biological research problems that can be addressed by exploiting the whole-genome and positional perspectives of Map Viewer. Please be aware that the examples in these tutorials may return different results when you execute them, because the underlying da ...
... instructions are provided for several common biological research problems that can be addressed by exploiting the whole-genome and positional perspectives of Map Viewer. Please be aware that the examples in these tutorials may return different results when you execute them, because the underlying da ...
Test Info Sheet
... sporadic. Aniridia may be caused by heterozygous mutations in the PAX6 gene. PAX6 mutations have also been described in a host of other ocular developmental abnormalities that appear clinically distinct from aniridia, including: microphthalmia with or without coloboma; optic nerve hypoplasia and oth ...
... sporadic. Aniridia may be caused by heterozygous mutations in the PAX6 gene. PAX6 mutations have also been described in a host of other ocular developmental abnormalities that appear clinically distinct from aniridia, including: microphthalmia with or without coloboma; optic nerve hypoplasia and oth ...
Articles - American Scientist
... in more detail in the 3D model on the cover of this magazine. The stargate substructure of genetic material and protein coat) viruses. This unprecedented property lacks fibers and is visible as an indentation has an icosahedral core of ~500 nano- and other features of its lifestyle have in the fiber ...
... in more detail in the 3D model on the cover of this magazine. The stargate substructure of genetic material and protein coat) viruses. This unprecedented property lacks fibers and is visible as an indentation has an icosahedral core of ~500 nano- and other features of its lifestyle have in the fiber ...
A DNA-sequence based phylogeny for triculine snails (Gastropoda
... For each data set a χ 2 -test for intertaxon variation in nucleotide frequency was performed using PAUP∗ v. 4.0b10 (Swofford, 2002). The data were tested for (substitution) saturation using plots of the numbers of transitions and transversions against the genetic distances estimated under the approp ...
... For each data set a χ 2 -test for intertaxon variation in nucleotide frequency was performed using PAUP∗ v. 4.0b10 (Swofford, 2002). The data were tested for (substitution) saturation using plots of the numbers of transitions and transversions against the genetic distances estimated under the approp ...
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... obligate endosymbionts such as Blochmannia poses distinct experimental challenges. First, the inability to culture Blochmannia outside the host required that we isolate Blochmannia cells from C. pennsylvanicus workers prior to DNA preparation within agarose plugs. This direct isolation from hosts ne ...
... obligate endosymbionts such as Blochmannia poses distinct experimental challenges. First, the inability to culture Blochmannia outside the host required that we isolate Blochmannia cells from C. pennsylvanicus workers prior to DNA preparation within agarose plugs. This direct isolation from hosts ne ...
Special Feature —Manipulating Genes to Understand
... advances in our understanding of the mechanisms of gene expression and regulation and the development of animal models of human diseases are but two examples of how this technology has affected medical science. Transgenic animals are defined as animals in which a segment of DNA has been physically i ...
... advances in our understanding of the mechanisms of gene expression and regulation and the development of animal models of human diseases are but two examples of how this technology has affected medical science. Transgenic animals are defined as animals in which a segment of DNA has been physically i ...
Dynamics and control of DNA sequence amplification
... operating conditions is required. However, in the absence of such a dynamic model, the operating conditions for PCR reactions are typically selected based on analysis of reaction thermodynamics, and, to a lesser extent, qualitative analysis of reaction kinetics. Reductions in cycle efficiency (eithe ...
... operating conditions is required. However, in the absence of such a dynamic model, the operating conditions for PCR reactions are typically selected based on analysis of reaction thermodynamics, and, to a lesser extent, qualitative analysis of reaction kinetics. Reductions in cycle efficiency (eithe ...
You`re one in a googol: optimizing genes for protein expression
... There is an implicit assumption that, because we know the genetic code, it will be straightforward to choose a DNA sequence to encode any protein. But we need to think about more than the sequences that will ensure enough mRNA and an adequate rate of translational initiation: the codon choices thems ...
... There is an implicit assumption that, because we know the genetic code, it will be straightforward to choose a DNA sequence to encode any protein. But we need to think about more than the sequences that will ensure enough mRNA and an adequate rate of translational initiation: the codon choices thems ...
SpliceCenter_DataBuild
... database build process. Dr. Kahn and Zeeberg developed a splice variant database, EVDB [5], which was based on NCBI Evidence Viewer [8] data. EVDB demonstrated the merits of constructing a repository of distinct splice variants that included each variant’s exon structure in chromosomal coordinates. ...
... database build process. Dr. Kahn and Zeeberg developed a splice variant database, EVDB [5], which was based on NCBI Evidence Viewer [8] data. EVDB demonstrated the merits of constructing a repository of distinct splice variants that included each variant’s exon structure in chromosomal coordinates. ...
The Acquisition of Student Nurses` Knowledge of Genetics
... The completion of the Human Genome Project (HGP) in 2003 marked a turning point in the history of genomic knowledge and resources available for healthcare professionals including nurses (Thompson & Brooks, 2010). It was not until after the completion of the HGP that 49 nursing organizations came to ...
... The completion of the Human Genome Project (HGP) in 2003 marked a turning point in the history of genomic knowledge and resources available for healthcare professionals including nurses (Thompson & Brooks, 2010). It was not until after the completion of the HGP that 49 nursing organizations came to ...