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Profile Documents Logout
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2012
2012

... Circle the correct answer 23. [3 points] Describe briefly the relationship between chromatin structure and transcription in eukaryotes. In eukaryotic chromosomes promoter access is restricted. Condensed chromatin is inaccessible and must be remodeled. Remodeling can occur through covalent modificati ...
Alignments -> Database Searching
Alignments -> Database Searching

... Protein function can be divided into three broad areas: molecular function, biological process and cellular component. Molecular function describes activity at the molecular level, such as catalysis, which is commonly predicted through methods that identify homologues or orthologues. Biological pro ...
Effects of mutations
Effects of mutations

... possible carcinogens by looking for mutations to occur. Once a mutagen is identified, it is tested in animals to test if it is a carcinogen. ...
Microbial pathogenesis - International Microbiology
Microbial pathogenesis - International Microbiology

It used to be thought that new proteins only evolved as a
It used to be thought that new proteins only evolved as a

... proteins could evolve much more suddenly. One of the first was 30 years ago when a study showed how a single extra base of DNA could create a new protein. Proteins are composed of amino acids, and three nucleotide bases (or “letters”) of DNA determines which of 20 possible amino acids is eventually m ...
Some Topics in Philosophy of Biology
Some Topics in Philosophy of Biology

Topic: Genetic Mutations
Topic: Genetic Mutations

... • How is reading the DNA like a recipe? • What happens when recipes go wrong? • How does a wrong recipe relate to having the wrong “DNA” recipe? ...
14MG-Website-Content-Draft-v2-2014-11-10
14MG-Website-Content-Draft-v2-2014-11-10

... knowledge will enable us to develop clinical diagnotstic tools to improve the diagnosis, treatment and outcomes of patients affected by these diseases. ...
Horizontal gene transfer of antimicrobial
Horizontal gene transfer of antimicrobial

... (MRSA) acquires AMR genes at very high frequency as it colonizes the host, but also loses resistances frequently. We have now built laboratory models to investigate how this gene transfer occurs, how it is regulated, whether we can encourage resistance gene loss and how AMR populations evolve. These ...
Chapter 2- Genetics
Chapter 2- Genetics

...  Free-floating nucleotides in cells are derived from the food one eats.  ____ new strands of DNA are formed into the double helix. f) The genetic code  With only 4 bases, billions of genes can be coded.  Proteins are made from specific _______ __________________ called genes.  A protein is a ch ...
Bacterial plasmids
Bacterial plasmids

Recombination and Genetic Engineering
Recombination and Genetic Engineering

... and the termini tend to be l0 to 40 base pairs in length with perfect or nearly perfect repeats. These sequences also tend to have RNA termination signals as well as nonsense codons in all three reading frames and are therefore polar. Typically they encode one large open reading frame of 300 to 400 ...
DNA Extraction Lab
DNA Extraction Lab

... In this investigation, you will isolate DNA from strawberries and liver. DNA is 100 000 times longer than the cell itself, but only takes up about 10% of the space in the cell. It achieves this by tight folding and packaging with proteins. DNA extraction is the first step in many biotechnological pr ...
DNA damage and repair
DNA damage and repair

Answers to Problem Set 3A
Answers to Problem Set 3A

... 4. What does telomerase use as template for synthesizing more DNA on the ends of chromosomes? What does it use as primer? It uses its own RNA as template and uses the 3’ hydroxyl on the DNA at the end of the chromosome as its primer. 5. Why do Ds elements need the presence of an Ac element in order ...
presentation UCSC part 1 - Biomedical Genomics Group
presentation UCSC part 1 - Biomedical Genomics Group

... We will walk through them together 2 styles: questions only, and step-by-step When we are finished the formal exercises, we can help you to investigate issues that you want to understand for your research ...
Recombinant DNA and Gene Cloning
Recombinant DNA and Gene Cloning

... But how to detect those clones of E. coli that have been transformed by a plasmid carrying a piece of human DNA? The key is that the EcoRI site is within the kanr gene, so when a piece of human DNA is inserted there, the gene's function is destroyed. All E. coli cells transformed by the vector, whet ...
DNA, RNA, and Protein Synthesis Notes
DNA, RNA, and Protein Synthesis Notes

... Translation - process where proteins are made from RNA Where: in the cytoplasm; at a ribosome ...
EOC Review Jeopardy EOC Double Jeopardy
EOC Review Jeopardy EOC Double Jeopardy

DNA
DNA

DNA notes 2015 - OG
DNA notes 2015 - OG

... An insertion mutation is when a nitrogen base is added to the existing DNA A deletion mutation is when a nitrogen base is subtracted from the DNA A substitution mutation is when one nitrogen base is put in place of another. If our DNA was AATTGGCC An insertion would be AATTAGGCC A deletion would be ...
Recombinant DNA
Recombinant DNA

... – Compare genomes of organisms – Identify similarities between the sequence of human bases and those of other organisms – Provide way to study genome changes through time • Track evolution of HIV ...
Mutations
Mutations

... – Change in third position often does nothing – Change in second position often either does nothing or changes one amino acid for a similar one ...
Determining Compensatory Genes from Loss of Vacuolar
Determining Compensatory Genes from Loss of Vacuolar

... We have successfully compared the complete genomes of two different mutant strains of Saccharomyces cerevisiae, vsp33 and vsp41, to a wild type strain using DNA microarray technology. Repeated trials have consistently shown up-regulation of 12 different genes in both mutant strains (Tables 1 & 2). A ...
Lecture 6 - EukDNAexpression2007 - Cal State LA
Lecture 6 - EukDNAexpression2007 - Cal State LA

...  Late gene transcription occurs during and after DNA replication and is controlled by regulatory proteins and the configuration of the newly made DNA.  After DNA replication begins, early mRNAs are not transcribed as efficiently, therefore less early mRNA is made. Those that are made are also degr ...
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Genomics

Genomics is a discipline in genetics that applies recombinant DNA, DNA sequencing methods, and bioinformatics to sequence, assemble, and analyze the function and structure of genomes (the complete set of DNA within a single cell of an organism). Advances in genomics have triggered a revolution in discovery-based research to understand even the most complex biological systems such as the brain. The field includes efforts to determine the entire DNA sequence of organisms and fine-scale genetic mapping. The field also includes studies of intragenomic phenomena such as heterosis, epistasis, pleiotropy and other interactions between loci and alleles within the genome. In contrast, the investigation of the roles and functions of single genes is a primary focus of molecular biology or genetics and is a common topic of modern medical and biological research. Research of single genes does not fall into the definition of genomics unless the aim of this genetic, pathway, and functional information analysis is to elucidate its effect on, place in, and response to the entire genome's networks.
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