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MIDWESTERN ASSOCIATION OF FORENSIC SCIENTISTS, INC
MIDWESTERN ASSOCIATION OF FORENSIC SCIENTISTS, INC

... explained through the microscope by projection. Particles that require specialized analytical instrumentation for certain identification will be pointed out when encountered and the techniques of dealing with them will be described, specifically with respect to types of information that may be obtai ...
Conjugative plasmids: vessels of the communal gene pool
Conjugative plasmids: vessels of the communal gene pool

Conjugative plasmids: vessels of the communal gene pool
Conjugative plasmids: vessels of the communal gene pool

... These two factors, compactness and gene clustering, mean that many conferrable traits can be transferred between discrete replicating elements (chromosomes or plasmids) by the movement of relatively small fragments of DNA. Phylogenetic analyses of complete genomes have also shown that some prokaryot ...
Chapter 29 Slides
Chapter 29 Slides

... Genetic Information Can Be Transferred Between Bacteria • In 1946, Lederberg and Tatum showed that two different strains of bacteria with different growth requirements could exchange genes • Lederberg and Tatum surmised that the bacterial cells must interact with each other - the process is now know ...
2. Assessing the probative value of DNA evidence
2. Assessing the probative value of DNA evidence

Assessing the Probative Value of DNA Evidence
Assessing the Probative Value of DNA Evidence

... proceedings. We have stopped well short of presuming to specify formal criteria of legal admissibility or to formulate concrete guidance that judges might repeat to juries in criminal trials. It is not for us to make detailed recommendations on the law and practice of criminal procedure. ...
Chromosomes Carrying Meiotic Avoidance Loci
Chromosomes Carrying Meiotic Avoidance Loci

... apomixis in Hieracium praealtum. Genetic markers linked to these loci have been determined using a deletion mapping approach (Catanach et al., 2006). The roles of these two loci and their interactions with the sexual pathway have been determined from the analyses of apomixis mutants, transgenic abla ...
- Philsci-Archive
- Philsci-Archive

... inappropriate level, to explore some of the interrelationships among these notions, and locate them notions within a larger framework for discussing causation and explanation. I will also try to illustrate how a concern with whether causal relationships are specific, stable and so on arises in a ver ...
Nanopore Unzipping of Individual DNA Hairpin Molecules
Nanopore Unzipping of Individual DNA Hairpin Molecules

... not entail the physical coupling of the molecules under test to a force transducer, very high throughput can be achieved. We used our method to study DNA unzipping kinetics at small forces, which have not been accessed before. We find that in this regime the static unzipping times decrease exponentia ...
Biology 30 June 1999 Grade 12 Diploma Exam
Biology 30 June 1999 Grade 12 Diploma Exam

... In rare cases, human males develop functioning mammary glands. Hormone levels are known to affect the development and function of mammary glands in both males and females. ...
Understanding Reads in RNA-Seq Analysis
Understanding Reads in RNA-Seq Analysis

... This white paper explains some basic concepts related to alignment and mapping in Partek® Genomics Suite™ (PGS) v6.6 under the RNA-seq workflow. The term “alignment” describes the process of finding the position of a sequencing read on the reference genome, while “mapping” refers to assigning alread ...
MA112 Expresso® Rhamnose SUMO Cloning and
MA112 Expresso® Rhamnose SUMO Cloning and

... is designed for expression in E. coli, fusion clones constructed using this system can also be transferred into eukaryotic expression vectors for expression of SUMO-tagged proteins in mammalian or insect cells. The rhaP BAD promoter is a versatile tool for protein expression. In the absence of rhamn ...
Gene Ontology (GO) Tutorial
Gene Ontology (GO) Tutorial

Bacteroides mobilizable and conjugative genetic elements
Bacteroides mobilizable and conjugative genetic elements

... the tetQ-rteA-rteB operon, should be regulated similarly to production of TetQ. That is, the proteins are produce at detectable levels only when the cells are stimulated with tetracycline. Since rteA and rteB have been shown to be in the same operon as tetQ, production of these proteins is presumabl ...
New and Redesigned pRS Plasmid Shuttle Vectors for Genetic
New and Redesigned pRS Plasmid Shuttle Vectors for Genetic

... ABSTRACT We have constructed a set of 42 plasmid shuttle vectors based on the widely used pRS series for use in the budding yeast Saccharomyces cerevisiae and the bacterium Escherichia coli. This set of pRSII plasmids includes new shuttle vectors that can be used with histidine and adenine auxotroph ...
Youngson and Whitelaw, 2008
Youngson and Whitelaw, 2008

... Transgenerational epigenetic effects and transgenerational epigenetic inheritance are not the same, but a novice to the discipline would find this hard to understand. The situation has arisen because the word epigenetic has changed its meaning over the past fifty years. In the phrase ‘transgenerationa ...
Detecting copy number variants and runs of homozygosity on a
Detecting copy number variants and runs of homozygosity on a

... or syndrome is a key objective in human genetics. Copy number variants (CNVs) and other forms of structural variation are important in understanding the underlying mechanisms to many common diseases. CNVs are defined as chromosomal segments, at least 1000 bases in length that vary in copy number (CN ...
The Effects of Deleterious Mutations on Evolution at
The Effects of Deleterious Mutations on Evolution at

Codon usage bias from tRNA`s point of view
Codon usage bias from tRNA`s point of view

... genomes. This suggests an optimization of the translation machinery to use a small subset of optimal codons and anticodons in fast-growing bacteria and in highly expressed genes. As a result, the overrepresented codons in highly expressed genes tend to be the same in very different genomes to match ...
Minimum SNPs version 2043 user manual
Minimum SNPs version 2043 user manual

... can be accurately sequenced on both strands using an automated DNA sequencer. For each house-keeping gene, the different sequences present within a bacterial species are assigned as distinct alleles and, for each isolate, the alleles at each of the seven loci define the allelic profile or sequence t ...
Genes and Genetic Testing in Hereditary Ataxias
Genes and Genetic Testing in Hereditary Ataxias

... of dominant ataxias is repeat expansions, where increasing lengths of repeated DNA sequences result in non-functional proteins that accumulate in the body causing disease. Greater understanding of all ataxia genes has helped identify several different pathways, such as DNA repair, ubiquitination, an ...
controlling flowering time and plant height in
controlling flowering time and plant height in

... et a!. (1993). However, in many cases the traits vary quantitatively suggesting that they are controlled by many genes. Molecular marker maps, usually based on RFLPs, have been widely used to map quantitative trait loci ...
Full text - PAHdb - McGill University
Full text - PAHdb - McGill University

... databases recapitulate the science in their various ways and they can recreate it in silico. Databases have thus become necessary resources in genetics. They are repositories of the vast wealth of data being gathered about individual genes and the genomes they inhabit. PAHdb is one such legacy and r ...
The murine homologue of HIRA, a DiGeorge
The murine homologue of HIRA, a DiGeorge

... commonly deleted region (17). The two SRDOs are mutually exclusive. At present it is not clear whether the CATCH22 phenotype is the result of haploinsufficiency of one or more genes. The balanced t(2;22)(q14.1;q11.1) translocation breakpoint in DGS patient ADU (20) was the major target of positional ...
Direct and indirect consequences of meiotic recombination
Direct and indirect consequences of meiotic recombination

... The second, which we term ‘hotspot drive’, results from the biased transmission of non-recombinogenic alleles over recombinogenic ones in hotspots of recombination [19]. The third, which we term ‘indel drive’, refers to the biased transmission of either the shorter or longer allele of an indel durin ...
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Genomics

Genomics is a discipline in genetics that applies recombinant DNA, DNA sequencing methods, and bioinformatics to sequence, assemble, and analyze the function and structure of genomes (the complete set of DNA within a single cell of an organism). Advances in genomics have triggered a revolution in discovery-based research to understand even the most complex biological systems such as the brain. The field includes efforts to determine the entire DNA sequence of organisms and fine-scale genetic mapping. The field also includes studies of intragenomic phenomena such as heterosis, epistasis, pleiotropy and other interactions between loci and alleles within the genome. In contrast, the investigation of the roles and functions of single genes is a primary focus of molecular biology or genetics and is a common topic of modern medical and biological research. Research of single genes does not fall into the definition of genomics unless the aim of this genetic, pathway, and functional information analysis is to elucidate its effect on, place in, and response to the entire genome's networks.
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