The American University in Cairo School of Science and Engineering
... thought that the amino acid substitutions result in the enlargement of the active site resulting in novel enzyme-substrate interactions that take place between the large oxyimino substituents of the extended-spectrum cephalosporins (Sturenburg and Mack, ...
... thought that the amino acid substitutions result in the enlargement of the active site resulting in novel enzyme-substrate interactions that take place between the large oxyimino substituents of the extended-spectrum cephalosporins (Sturenburg and Mack, ...
Variant Effect Predictor Web interface Documentation
... most rich annotation through the VEP. GENCODE Basic is a subset of the GENCODE gene set, and is intended to provide a simplified, high-quality subset of the GENCODE transcript annotations that will be useful to the majority of users. GENCODE Basic includes all genes in the GENCODE gene set, with a r ...
... most rich annotation through the VEP. GENCODE Basic is a subset of the GENCODE gene set, and is intended to provide a simplified, high-quality subset of the GENCODE transcript annotations that will be useful to the majority of users. GENCODE Basic includes all genes in the GENCODE gene set, with a r ...
List of references - UC Davis Plant Sciences
... Despres, C., M. Sabaelleil, S.R. Rivard and D. Morse. 1994. Molecular cloning of two Solanum chacoense S-alleles and a hypothesis concerning their evolution. Sexual Plant Reproduction 7:169-176. du Jardin, P. 1990. Homologies to plastid DNA in the nuclear and mitochondrial genomes of potato. TAG 79: ...
... Despres, C., M. Sabaelleil, S.R. Rivard and D. Morse. 1994. Molecular cloning of two Solanum chacoense S-alleles and a hypothesis concerning their evolution. Sexual Plant Reproduction 7:169-176. du Jardin, P. 1990. Homologies to plastid DNA in the nuclear and mitochondrial genomes of potato. TAG 79: ...
Harvey ras (H-ras) Point Mutations Are Induced by 4
... stained cryosections and dissected (Fig. 1). Genomic DNA was iso lated from the lesion and amplified by nested PCR. RFLP Analysis. 4NQO acting as a DNA alkylating agent should result in 0 to A transversion (4,5). Of the codons previously impli cated in H-ras activation, codon 12 has two available G ...
... stained cryosections and dissected (Fig. 1). Genomic DNA was iso lated from the lesion and amplified by nested PCR. RFLP Analysis. 4NQO acting as a DNA alkylating agent should result in 0 to A transversion (4,5). Of the codons previously impli cated in H-ras activation, codon 12 has two available G ...
mic.sgmjournals.org
... Corynebacterium glutamicum is a Gram-positive organism, isolated by Kinoshita and coworkers as a biotin-auxotrophic bacterium, that excretes large amounts of Lglutamate when grown aerobically under biotin limitation with glucose as a carbon source (Kinoshita et al., 1957; Kikuchi & Nakao, 1986). C. ...
... Corynebacterium glutamicum is a Gram-positive organism, isolated by Kinoshita and coworkers as a biotin-auxotrophic bacterium, that excretes large amounts of Lglutamate when grown aerobically under biotin limitation with glucose as a carbon source (Kinoshita et al., 1957; Kikuchi & Nakao, 1986). C. ...
Genomic analysis of clinical samples with serologic ABO blood
... by a missense or nonsense mutation for which screening by allele-specific primer polymerase chain reaction was performed. The novel mutations were encountered in 28 of the remaining 60 A and B subgroup samples but not among normal donors. As a result of this study, the number of definable alleles as ...
... by a missense or nonsense mutation for which screening by allele-specific primer polymerase chain reaction was performed. The novel mutations were encountered in 28 of the remaining 60 A and B subgroup samples but not among normal donors. As a result of this study, the number of definable alleles as ...
molecular genetics of tibial muscular dystrophy (tmd) and - E
... During the preceding two decades, there has been immense progress in resolving the molecular genetic background of the inherited muscular dystrophies and myopathies. Most of the classified entities have been assigned to a chromosomal locus or the causative gene and mutations are known. This has resu ...
... During the preceding two decades, there has been immense progress in resolving the molecular genetic background of the inherited muscular dystrophies and myopathies. Most of the classified entities have been assigned to a chromosomal locus or the causative gene and mutations are known. This has resu ...
Designing synthetic MLPA probes - MRC
... Hybridising parts of LPO and RPO. Bind to adjacent target DNA sequences. Probe oligonucleotide that is situated on the left when probe is shown from 5’ to 3’. Consists of forward PCR primer sequence (5’ end) and hybridising sequence (3’ end). 3’ nucleotide of LPO and 5’ nucleotide of RPO, where liga ...
... Hybridising parts of LPO and RPO. Bind to adjacent target DNA sequences. Probe oligonucleotide that is situated on the left when probe is shown from 5’ to 3’. Consists of forward PCR primer sequence (5’ end) and hybridising sequence (3’ end). 3’ nucleotide of LPO and 5’ nucleotide of RPO, where liga ...
HW4_final
... Transcription Factors (which usually bind double-stranded DNA) and compete with the natural promoter of a gene which is regulated by that Transcription Factor. This is another elegant way by which the cell can regulate the gene expression. To-date there are only very few known examples of lncRNA tha ...
... Transcription Factors (which usually bind double-stranded DNA) and compete with the natural promoter of a gene which is regulated by that Transcription Factor. This is another elegant way by which the cell can regulate the gene expression. To-date there are only very few known examples of lncRNA tha ...
A MIAME-compliant Microarray Database
... • Contains information about how words in the ontology relate to one another • Allows computers to understand annotation as well as humans ...
... • Contains information about how words in the ontology relate to one another • Allows computers to understand annotation as well as humans ...
Why are most organelle genomes transmitted maternally?
... mechanisms are variable between organisms and organelles. For example, sorting-out of plastids in seed plants is a rapid process that is typically completed before flower formation (Fig. 1). In contrast, at least in some animal systems, heteroplasmy (in the germ line) can persist for several generat ...
... mechanisms are variable between organisms and organelles. For example, sorting-out of plastids in seed plants is a rapid process that is typically completed before flower formation (Fig. 1). In contrast, at least in some animal systems, heteroplasmy (in the germ line) can persist for several generat ...
WASP - Genome Institute, BIOTEC
... Background: Allele-specific (AS) Polymerase Chain Reaction is a convenient and inexpensive method for genotyping Single Nucleotide Polymorphisms (SNPs) and mutations. It is applied in many recent studies including population genetics, molecular genetics and pharmacogenomics. Using known AS primer de ...
... Background: Allele-specific (AS) Polymerase Chain Reaction is a convenient and inexpensive method for genotyping Single Nucleotide Polymorphisms (SNPs) and mutations. It is applied in many recent studies including population genetics, molecular genetics and pharmacogenomics. Using known AS primer de ...
IMPROVE SMALL RNA-MEDIATED GENE SILENCING
... trigger in Caenorhabditis elegans and proposed the term RNA interference (RNAi) for the first time (Fire et al. 1998). Later on, the potency of dsRNA to induce gene silencing was also demonstrated in plants (Waterhouse et al. 1998), protozoa (Ngo et al. 1998), and insects (Kennerdell and Carthew 199 ...
... trigger in Caenorhabditis elegans and proposed the term RNA interference (RNAi) for the first time (Fire et al. 1998). Later on, the potency of dsRNA to induce gene silencing was also demonstrated in plants (Waterhouse et al. 1998), protozoa (Ngo et al. 1998), and insects (Kennerdell and Carthew 199 ...
Genetic studies of psoriasis and psoriatic arthritis
... PSORS5 yielded no significant association. It is therefore unlikely that they harbor the genetic cause of psoriasis at this locus. Fine-mapping of the PSORS5 region revealed both point-wise and haplotype associations that might contribute to psoriasis susceptibility. The only gene within this region ...
... PSORS5 yielded no significant association. It is therefore unlikely that they harbor the genetic cause of psoriasis at this locus. Fine-mapping of the PSORS5 region revealed both point-wise and haplotype associations that might contribute to psoriasis susceptibility. The only gene within this region ...
T-box-mediated control of the anabolic proline biosynthetic genes of
... Vitreschak et al., 2008; Wels et al., 2008; Winkler, 2007). Tbox systems are RNA-based regulatory switches (Henkin, 2008) that are used in many Gram-positive microorganisms to regulate the expression of aminoacyl-tRNA synthetase genes and of genes involved in amino acid ...
... Vitreschak et al., 2008; Wels et al., 2008; Winkler, 2007). Tbox systems are RNA-based regulatory switches (Henkin, 2008) that are used in many Gram-positive microorganisms to regulate the expression of aminoacyl-tRNA synthetase genes and of genes involved in amino acid ...
Fulltext - Jultika
... characterized here. It was found to consist of 68 exons and span 160 kb, excluding introns 1 and 4. Over 50 kb of new intronic sequences were defined. The exon-intron organization coding for the major triple helical domain was found to be identical to that of the human COL11A2 gene, which codes for ...
... characterized here. It was found to consist of 68 exons and span 160 kb, excluding introns 1 and 4. Over 50 kb of new intronic sequences were defined. The exon-intron organization coding for the major triple helical domain was found to be identical to that of the human COL11A2 gene, which codes for ...
NIH Public Access
... by standard extraction-based approaches, we pursued a different approach to manipulate the binding or release of XIST RNA directly within living cells. This strategy built upon a significant clue from our earlier demonstration that XIST RNA releases from the mitotic Xi during early prophase in human ...
... by standard extraction-based approaches, we pursued a different approach to manipulate the binding or release of XIST RNA directly within living cells. This strategy built upon a significant clue from our earlier demonstration that XIST RNA releases from the mitotic Xi during early prophase in human ...
Getting Started With Gel Electrophoresis
... Due to their relatively small molecular weight, the dyes will continue to diffuse after the electrophoresis is finished. For this reason, make sure to take any measurements or photos shortly after the run is complete. By the following day, the bands of dye will not be clearly defined in the gel. ...
... Due to their relatively small molecular weight, the dyes will continue to diffuse after the electrophoresis is finished. For this reason, make sure to take any measurements or photos shortly after the run is complete. By the following day, the bands of dye will not be clearly defined in the gel. ...
Careful risk assessment needed to evaluate transgenic fish
... probability of carrying human pathogens, and the fact that aquaculture is ...
... probability of carrying human pathogens, and the fact that aquaculture is ...
Conservation of Brachyury (T) genes in amphioxus and vertebrates
... end of the tail bud stage (Wilkinson et al., 1990; Herrmann, 1991; Herrmann and Kispert, 1994). Recently the Brachyury protein has been shown to act as a transcription factor (Kispert, Koschorz and Herrmann, unpublished data), which binds specifically to a palindromic recognition sequence in vitro. ...
... end of the tail bud stage (Wilkinson et al., 1990; Herrmann, 1991; Herrmann and Kispert, 1994). Recently the Brachyury protein has been shown to act as a transcription factor (Kispert, Koschorz and Herrmann, unpublished data), which binds specifically to a palindromic recognition sequence in vitro. ...
A Novel Mouse Chromosome 17 Hybrid Sterility Locus
... The effects of heterospecific combinations of mouse chromosome 17 on male fertility and transmission ratio were investigated through a series of breeding studies. Animals were bred to carry complete chromosome 17 homologs, or portions thereof, from three differentsources-Mus domesticus, Mus spretus ...
... The effects of heterospecific combinations of mouse chromosome 17 on male fertility and transmission ratio were investigated through a series of breeding studies. Animals were bred to carry complete chromosome 17 homologs, or portions thereof, from three differentsources-Mus domesticus, Mus spretus ...
Identification and isolation of active N2O reducers in rice paddy soil
... the 16S rRNA and functional gene diversities of microbial populations involved in specific functions. Previously, 13C-assimilating populations under denitrifying conditions were analyzed by DNA-based SIP analysis (Ginige et al., 2004; Osaka et al., 2006; Osaka et al., 2008; Saito et al., 2008). Howe ...
... the 16S rRNA and functional gene diversities of microbial populations involved in specific functions. Previously, 13C-assimilating populations under denitrifying conditions were analyzed by DNA-based SIP analysis (Ginige et al., 2004; Osaka et al., 2006; Osaka et al., 2008; Saito et al., 2008). Howe ...
Evolution of Closely Linked Gene Pairs in
... of base pairs between the beginning and/or ends of the transcripts as annotated in Ensembl. In the better annotated genomes, this includes the 5# and 3# untranslated regions (UTR); in poorly annotated genomes, information about the UTRs may be incomplete, and the number of closely linked gene pairs ...
... of base pairs between the beginning and/or ends of the transcripts as annotated in Ensembl. In the better annotated genomes, this includes the 5# and 3# untranslated regions (UTR); in poorly annotated genomes, information about the UTRs may be incomplete, and the number of closely linked gene pairs ...
Full-Text PDF
... to different antibiotic classes and can be used to direct therapy, but are slow and take up to 72 h. In the absence of rapid results, treatment will often use broad-spectrum antibiotics on an empirical basis, which may contribute to increased drug resistance. The emergence of multi-drug-resistant (M ...
... to different antibiotic classes and can be used to direct therapy, but are slow and take up to 72 h. In the absence of rapid results, treatment will often use broad-spectrum antibiotics on an empirical basis, which may contribute to increased drug resistance. The emergence of multi-drug-resistant (M ...