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Noncoding DNA - University of Mysore
Noncoding DNA - University of Mysore

... induces transcription of the satellite III sequences, located on centromeric heterochromatin of human chromosomes 9 and 11. A variety of RNA processing proteins, RNA polymerase II and heat shock transcription factor etc get sequestered with these transcripts as stress granules in heat shocked human ...
lecture 21
lecture 21

... information from parent to offspring Horizontal gene transfer: transfer of genetic information from one genome to another between two species (horizontal) or between ...
Model for transcriptional activation
Model for transcriptional activation

... Eukaryotic Promoters • Three classes of eukaryotic promoters: I, II and III which are recognized by RNA Pol I, II, and III, respectively. • Class I promoters not well conserved in sequence amongst different species but general architecture consists of a core element and an upstream promoter element ...
The DNA Connection
The DNA Connection

...  A single base may be substituted for another  One or more bases may be removed from a section of DNA or new bases inserted Some mutations happen during Meiosis:  Chromosomes don’t separate correctly  Cell can end up with too many or too few chromosomes  Cell could end up with fragments of chro ...
Biochemistry I (CHE 418 / 5418)
Biochemistry I (CHE 418 / 5418)

... –discrete, functional unit of DNA –when expressed, (transcribed) yields a functional product • rRNA, tRNA, snRNA • mRNA - translated into a polypeptide sequence. –Open reading frame - long stretch of nucleotides that can encode polypeptide due to absence of stop codons. ...
RrYy - Lemon Bay High School
RrYy - Lemon Bay High School

... cells. • four genetically different haploid cells. • four genetically identical haploid cells. • two genetically different diploid cells. ...
Dragonfly genome project
Dragonfly genome project

... Phylogeny: dragonfly among another insects Ancient and interesting, but not so well known insects ...
Nucleic Acids, the Genetic Code, and the Synthesis of
Nucleic Acids, the Genetic Code, and the Synthesis of

... Both DNA and RNA chains are produced by copying of template DNA strands Nucleic acid strands (poly-nucleotides) grow by the addition of one nucleotide at a time, and always in the 5’ -> 3’ direction RNA polymerases can initiate strand growth but DNA polymerases require a primer strand The primary po ...
Question How does DNA control a cell?By controlling Protein
Question How does DNA control a cell?By controlling Protein

... Left-over ...
Gene Section AF4 (ALL1 fused gene from chromosome 4)
Gene Section AF4 (ALL1 fused gene from chromosome 4)

... Additional chromosome anomalies are found in ¼ of cases of which is the i(7q). Hybrid/Mutated Gene 5’ MLL - 3’ AF4; 12 kb. Abnormal Protein 240 kDa protein with about 1400 amino acids from NH2 MLL and 850 from COOH AF4 (variable breakpoints); the reciprocal may or may not be expressed. ...
Transcription in Eukaryotes Eukaryotes have 3 different RNA
Transcription in Eukaryotes Eukaryotes have 3 different RNA

... •5 of 7 aa’s of heptad have ‘-OH’ groups that can be phosphorylated ...
Biosketch - UNC School of Medicine - UNC
Biosketch - UNC School of Medicine - UNC

... 4) Defining the impact of genomic imprinting on transcriptional output in mammals. Genomic imprinting is an epigenetic process initiated during mammalian gametogenesis, which results in preferential expression of genes from one parentally inherited allele over the other. Over one hundred fifty impr ...
Transcription
Transcription

... a. Larger genome size with many non-coding regions. Prokaryotes do not have non-coding regions. b. Compartmentalization within the cell. Nuclear encoded gene products must be transported to organelles. c. More extensive transcript processing; introns removed, 5’ cap and ...
Developmental Biology 8/e - Florida International University
Developmental Biology 8/e - Florida International University

... 9.28 Expression and regulatory interactions among gap genes products High levels of Bicoid and Hunchback induce the expression of giant, while Kruppel transcript appears over the region where Hunchback begins to decline. ...
240.1 Caren
240.1 Caren

... been alleged to contain one or more tumor suppressor genes. We and others have previously narrowed down this region to 1p36.2-3 and more specifically to the gene region involving the genes: UBE4B-KIF1BPGD-CORT-DFFA-PEX14. The known genes in the region have been analyzed for mutations and a few have ...
Genetics exam 4
Genetics exam 4

... B. A sugar-phosphate bond is formed between the 3' hydroxyl and the 5' phosphate C. Deoxyribonucleotides are incorporated into the growing sequence D. Both RNA and DNA polymerase require oligonucleotide priming E. Both RNA and DNA polymerase initiate at promoter sequences _____ Which of the followin ...
PowerPoint 簡報
PowerPoint 簡報

... which inactivate them. These dead genes are called pseudogenes. • These processed pseudogenes have probably been produced by the reverse transcription of the mature mRNA transcript of a gene (which will itself lack introns and promoter sequences. • Pseudogenes are sometimes found on a different chro ...
No Slide Title
No Slide Title

... orders on the basis of their mechanistic features, sequence organization, and reverse transcriptase phylogeny: LTR retrotransposons, DIRS-like elements, Penelope-like elements, LINEs, and SINEs. ...
How Proteins are Made - MDC Faculty Web Pages
How Proteins are Made - MDC Faculty Web Pages

... that acts as a binding site for RNA polymerase) to copy all three genes as one transcript. • Between promoter and first gene is a region called the operator, a sequence of DNA that can act in two different states. – The operator can bind a repressor (protein from the i gene; only role is to regulate ...
Gene Section AF9 (ALL1 fused gene from chromosome 9)
Gene Section AF9 (ALL1 fused gene from chromosome 9)

... M5/M4 de novo and therapy related ANLL. Prognosis The prognosis may not be as poor as in other 11q23 leukaemias in de novo cases; very poor prognosis in secondary ANLL cases. Cytogenetics May be overlooked; often as a sole anomaly. Hybrid/Mutated Gene Variable breakpoints on both genes. Abnormal Pro ...
Secondary structures
Secondary structures

...  Unlike three dimensional structures of proteins, DNA molecules assume simple double helical structures independent on their sequences.  There are three kinds of double helices that have been observed in DNA: type A, type B, and type Z, which differ in their geometries. ...
DNA Replication
DNA Replication

... 1.Transcripts begin and end beyond the coding region ...
Genome Annotation - Virginia Commonwealth University
Genome Annotation - Virginia Commonwealth University

... previously cloned and sequenced looking for sequence similarity using BLAST programs Predict genes using computer programs to scan genomic DNA using known elements Many strategies use a combination of both ...
Gen677_Week5a_HGT_2012
Gen677_Week5a_HGT_2012

... * Environmental genes * Poorly characterized genes * Orphan genes (no homology to any known gene) * More mobile elements, phage sequences, repeats ...
dna sequence information independent technologies for
dna sequence information independent technologies for

... Gain of function mutagenesis-trait generator This is the final step in Transgenomics, where combinatorial matching of transactivator (pattern) lines from step 1 and UAS tagged (target) lines from step Occurs. Traditional genetic crossing between pattern and target lines allows transactivator protein ...
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Short interspersed nuclear elements (SINEs)

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