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Genetic engineering
Genetic engineering

... natural diversity that we observe among members of the same species as well as among different species. DNA sequences within most genes contain the information to direct the order of amino acids within polypeptides according to the genetic code. In the code, a three-base sequence specifies one parti ...
DNA - Snow Elementary School
DNA - Snow Elementary School

... 1. Watson and Crick showed: the two strands of the parental molecule separate, and each functions as a template for synthesis of a new complementary strand. ...
Genetic Mutations & Genetic Engineering
Genetic Mutations & Genetic Engineering

... Transformation: A cell takes in DNA from outside the cell Plasmid: Foreign DNA formed into a small circular DNA molecule. Used to incorporate foreign DNA into bacteria that will replicate allow it to be replicated Genetic Marker: Gene that makes it possible to distinguish bacteria that carry plasmid ...
Multiple Choice
Multiple Choice

... ____ 4. During mitosis, the a. DNA molecules unwind. b. histones and DNA molecules separate. c. DNA molecules become more tightly coiled. d. nucleosomes become less tightly packed. ____ 5. Unlike DNA, RNA contains a. adenine. c. phosphate groups. b. uracil. d. thymine. ____ 6. Which type(s) of RNA i ...
10.1 filled in notes CD
10.1 filled in notes CD

... like a rubber band twisted upon itself many times. ...
Science Notebook DNA, RNA, and Protein
Science Notebook DNA, RNA, and Protein

... Write the correct term in the left column for each definition below. process in which RNA is synthesized from DNA a group of three nitrogenous bases in DNA or mRNA that code for one amino acid nucleic acid made of ribose, phosphate, and one of four nitrogenous bases—adenine, cytosine, guanine, or ur ...
Nucleic Acids - cpprashanths Chemistry
Nucleic Acids - cpprashanths Chemistry

... P = Phosphate Group S= 5 Carbon Sugar (ribose or deoxyribose) B= Nitrogen Base ...
Palindromic Sequences
Palindromic Sequences

... insulin with performic acid. The sequence of fraction B was determined experimentally as being at least composed of phenylalanine, valine, aspartic acid, and glutamic acid, and well as threonine, proline, lysine, and alanine. This was done using a prepared sample of polypeptide fragments, which were ...
Introductory Biology Primer
Introductory Biology Primer

... • All hereditary information encoded in doublestranded DNA • Each cell in an organism has same DNA • DNA  RNA  protein • Proteins have many diverse roles in cell ...
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... of DNA from a complex mixture of DNA molecules. Major disadvantage: it is time-consuming (several days to produce recombinants) and, in parts, difficult procedure. The next major technical breakthrough (1983) after gene cloning was PCR. It achieves the amplifying of a short fragment of a DNA molecul ...
DNA
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... A GENE Each gene is a segment of doublestranded DNA that holds the recipe for making a specific molecule, usually a protein. These recipes are spelled out in varying sequences of the four chemical bases in DNA: adenine (A), thymine (T), guanine (G) and cytosine (C). The bases for interlocking pairs ...
Unit Title
Unit Title

... Students will explain the role of DNA in protein synthesis. Cells store and use information to guide their functions. The genetic information stored in DNA directs the synthesis of the thousands of proteins that each cell requires. Errors that may occur during this process may result in mutations th ...
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NMEICT PROJECT

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Enzyme POGIL-PCR

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... •The nucleotide sequence of 33.8 × 106 nucleotides is known; the rest of the chromosome consists primarily of very short repeated sequences that do not code for proteins or RNA. •** A pseudogene is a nucleotide sequence of DNA closely resembling that of a functional gene, but containing numerous del ...
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... 1. Who proposed the structure of of nucleic acid? 2. Which are the three covalently bound parts of nucleotides? 3. What are the sugars of nucleic acid? 4. Which are the bases of nucleic acid? 5. How nucleotides polymerize to form nucleotides? 6. What are the features of nucleic acid defined by Watso ...
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... Human genome is over 3 Billion bases long, arranged on 23 chromosomes. ...
DNA Structure, Replication and Translation Review
DNA Structure, Replication and Translation Review

... 8. What are Okazaki fragments? Why is the DNA in the lagging strand synthesized in fragments rather than continuously? Okazaki fragments are the pieces of DNA that are synthesized on the lagging strand of DNA, which are later joined together to create a continuous strand of DNA. The lagging strand i ...
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Investigation 3: DNA - connorericksonbiology
Investigation 3: DNA - connorericksonbiology

wind your way around your own dna - Ozias
wind your way around your own dna - Ozias

... chromosomes (one chromosome in each pair coming from each parent). A CHROMOSOME Each of the 46 human chromosomes contains the DNA for hundreds or thousands of individual genes, the units of heredity. A GENE Each gene is a segment of double-stranded DNA that holds the recipe for making a specific mol ...
summary - VU Research Portal
summary - VU Research Portal

... of four essential DNA processes is discussed: (i) DNA organization, on storing DNA in cells; (ii) DNA replication, or how a copy of DNA is made for a daughter cell; (iii) DNA transcription, reading of the DNA to synthesize mRNA for the production of proteins; and (iv) DNA repair, which is needed whe ...
Biology 303 EXAM II 3/14/00 NAME
Biology 303 EXAM II 3/14/00 NAME

... 3. although DNA damage doesn't necessarily lead to mutation, when a mutation does occur it is always caused by DNA damage. 4. DNA damage can lead to mutation, but doesn't always. ...
Chapter 20 Inheritance, Genetics, and Molecular Biology So how
Chapter 20 Inheritance, Genetics, and Molecular Biology So how

... o Occurs when two different alleles are equally expressed in a heterozygote Multiple alleles o The gene exists in several allelic forms o A person only has 2 of the possible alleles o A good example is the ABO blood system o IA and IB are codominant alleles o The i allele is recessive to both IA and ...
Biology 303 EXAM II 3/14/00 NAME
Biology 303 EXAM II 3/14/00 NAME

... 3. although DNA damage doesn't necessarily lead to mutation, when a mutation does occur it is always caused by DNA damage. 4. DNA damage can lead to mutation, but doesn't always. ...
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Nucleosome



A nucleosome is a basic unit of DNA packaging in eukaryotes, consisting of a segment of DNA wound in sequence around eight histone protein cores. This structure is often compared to thread wrapped around a spool.Nucleosomes form the fundamental repeating units of eukaryotic chromatin, which is used to pack the large eukaryotic genomes into the nucleus while still ensuring appropriate access to it (in mammalian cells approximately 2 m of linear DNA have to be packed into a nucleus of roughly 10 µm diameter). Nucleosomes are folded through a series of successively higher order structures to eventually form a chromosome; this both compacts DNA and creates an added layer of regulatory control, which ensures correct gene expression. Nucleosomes are thought to carry epigenetically inherited information in the form of covalent modifications of their core histones.Nucleosomes were observed as particles in the electron microscope by Don and Ada Olins and their existence and structure (as histone octamers surrounded by approximately 200 base pairs of DNA) were proposed by Roger Kornberg. The role of the nucleosome as a general gene repressor was demonstrated by Lorch et al. in vitro and by Han and Grunstein in vivo.The nucleosome core particle consists of approximately 147 base pairs of DNA wrapped in 1.67 left-handed superhelical turns around a histone octamer consisting of 2 copies each of the core histones H2A, H2B, H3, and H4. Core particles are connected by stretches of ""linker DNA"", which can be up to about 80 bp long. Technically, a nucleosome is defined as the core particle plus one of these linker regions; however the word is often synonymous with the core particle. Genome-wide nucleosome positioning maps are now available for many model organisms including mouse liver and brain.Linker histones such as H1 and its isoforms are involved in chromatin compaction and sit at the base of the nucleosome near the DNA entry and exit binding to the linker region of the DNA. Non-condensed nucleosomes without the linker histone resemble ""beads on a string of DNA"" under an electron microscope.In contrast to most eukaryotic cells, mature sperm cells largely use protamines to package their genomic DNA, most likely to achieve an even higher packaging ratio. Histone equivalents and a simplified chromatin structure have also been found in Archea, suggesting that eukaryotes are not the only organisms that use nucleosomes.
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