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Lorem Ipsum - University of Western Australia
Lorem Ipsum - University of Western Australia

Intro Nervous System and Neurons
Intro Nervous System and Neurons

...  Concerned with conservation of energy  Can dominate sympathetic system. Books says antagonistic, but they are more complimentary ...
PDF
PDF

Synaptogenesis
Synaptogenesis

... Following the period of PCD, axonal pathways and synaptic connections are refined by collateral and synapse elimination. Red lines: elements to be eliminated. ...
Ch10 Reading Guide
Ch10 Reading Guide

... 1. Released neurotransmitters diffuse across ______________________________ and react with ____________________ that form structures called _______________ in or on the______________________ neuron membrane. 2. Some neurotransmitters cause ion channels to _________________________ , some cause ion c ...
Central Nervous System
Central Nervous System

...  Posterior (dorsal) horns (cell bodies of interneurons)  Anterior (ventral) horns (cell bodies of motor neurons)  Lateral horns in thoracic and superior lumbar cord ...
Neurons
Neurons

03/02 PPT - Molecular and Cell Biology
03/02 PPT - Molecular and Cell Biology

... 1. neurons are intrinsically different from one another 2. Differences in position are biochemical in nature 3. Differences are acquired early in development ...
Nerve
Nerve

... a) dorsal horn (more pointy) -dorsal horn neurons are responsible for somatosensation, temperature sensation and pain sensation (innervate the skin) b) ventral horn (more rounded) -ventral horn neurons are responsible for movement (innervate skeletal muscle) C. The Brain 1. Cerebral Cortex (slide #1 ...
The Nervous System
The Nervous System

Cardiovascular system
Cardiovascular system

... Santiago Ramón y Cajal Nobel prize in physiology and medicine 1906 ...
methods of neuroanatomy
methods of neuroanatomy

... Weakness: fiber of passage problem (i.e., inability to tell whether labeling is attributable to direct effects on cell bodies at the lesion site or instead to damage to axons that pass through the lesion but originate elsewhere). Autoradiography: emerges in 1970's. Exploits axoplasmic flow (first of ...
4-Nervous system I: Structure and organization
4-Nervous system I: Structure and organization

... West, L. J., C. M. Pierce and W. D. Thomas. 1962. Lysergic acid diethylamide: its effects on a male Asiatic elephant. Science 138:1100-1103. Harwood, P. 1963. Therapeutic dosage in small and large mammals . Science 139: 684-685. ...
PDF
PDF

... mesoderm migration. In Drosophila embryos, presumptive mesoderm cells invaginate, undergo an epithelial-tomesenchymal transition (EMT), and then spread over the ectoderm to form a monolayer. On p. 3975, Murray and Saint investigate what types of cell rearrangements occur during this example of mesod ...
PDF
PDF

... mesoderm migration. In Drosophila embryos, presumptive mesoderm cells invaginate, undergo an epithelial-tomesenchymal transition (EMT), and then spread over the ectoderm to form a monolayer. On p. 3975, Murray and Saint investigate what types of cell rearrangements occur during this example of mesod ...
Nervous System ppt
Nervous System ppt

... • By end of this lesson, you should be able to: • Differentiate between the central and peripheral nervous systems. • Subdivide the peripheral nervous system into smaller groupings. • Describe the structure and function of a nerve cell (neuron). ...
Study Guide for The Spinal Cord – Chapter 8, Part B Be familiar with
Study Guide for The Spinal Cord – Chapter 8, Part B Be familiar with

Neuron Structure and Function
Neuron Structure and Function

PDF
PDF

Dopamine axons of substantia nigra pars compacta neurons and
Dopamine axons of substantia nigra pars compacta neurons and

... Although mutated genes, protein aggregates, environmental toxins and other factors associated with PD are widely distributed in the nervous system and affect many classes of neurons, dopamine (DA) neurons of the substantia nigra pars compacta (SNc) show exceptional and selective vulnerability. One f ...
PDF
PDF

... numbers of neurons are initially generated, before approximately half of them undergo programmed cell death (PCD), often during synapse formation. The factors that regulate central neuron survival and synaptic specificity remain largely unknown, but now, Joshua Sanes and colleagues (see p. 4141) rep ...
Note: This hypothesis is mainly concerned with peripheral neurons
Note: This hypothesis is mainly concerned with peripheral neurons

... Miller and Kaplan (2001) Neuron 32:767-770 ...
nervous system divisions cns, pns 1
nervous system divisions cns, pns 1

... 3. Reaction/Response: – Motor output. – response to information processed through stimulation of effectors • muscle contraction, glandular secretion The activation of muscles or glands (typically via the release of neurotransmitters (NTs)) ...
Classifications of Neurons 1. Function 2. Structure 3. Shape
Classifications of Neurons 1. Function 2. Structure 3. Shape

nervous system development and histology
nervous system development and histology

... axons training behind them. Their extension is controlled by chemical cues in their outside environment that ultimately direct them toward their appropriate targets. ...
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Netrin



Netrins are a class of proteins involved in axon guidance. They are named after the Sanskrit word ""netr"", which means ""one who guides."" Netrins are genetically conserved across nematode worms, fruit flies, frogs, mice, and humans. Structurally, netrin resembles the extracellular matrix protein laminin.Netrins are chemotropic; a growing axon will either move towards or away from a higher concentration of netrin. Though the detailed mechanism of axon guidance is not fully understood, it is known that netrin attraction is mediated through UNC-40/DCC cell surface receptors and repulsion is mediated through UNC-5 receptors. Netrins also act as growth factors, encouraging cell growth activities in target cells. Mice deficient in netrin fail to form the hippocampal comissure or the corpus callosum.A proposed model for netrin activity in the spinal column of developing human embryos is that netrins are released by the floor plate and then are picked up by receptor proteins embedded in the growth cones of axons belonging to neurons in the developing spinal column. The bodies of these neurons remain stationary while the axons follow a path defined by netrins, eventually connecting to neurons inside the embryonic brain by developing synapses. Research supports that new axons tend to follow previously traced pathways, rather than being guided by netrins or related chemotropic factors.
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