Nucleolar Dominance - Indiana University Bloomington
... sets of rRNA genes. The dominance of X. laevis rRNA genes over X. borealis rRNA genes observed in hybrids can be mimicked using minigenes injected into frog oocytes (Reeder and Roan, 1984). When an X. laevis minigene is coinjected with an X. borealis minigene, the X. laevis rRNA gene is preferential ...
... sets of rRNA genes. The dominance of X. laevis rRNA genes over X. borealis rRNA genes observed in hybrids can be mimicked using minigenes injected into frog oocytes (Reeder and Roan, 1984). When an X. laevis minigene is coinjected with an X. borealis minigene, the X. laevis rRNA gene is preferential ...
Lecture 3-POSTED-BISC441-2012
... Hypothesis for the evolution of prostate cancer risk • Strong selection for compounds that enhance male reproductive function, even at a cost to females, and a cost to males, especially in terms of cancer risk * Seminal proteins evolve under sexual conflict - antagonistic coevolution between genome ...
... Hypothesis for the evolution of prostate cancer risk • Strong selection for compounds that enhance male reproductive function, even at a cost to females, and a cost to males, especially in terms of cancer risk * Seminal proteins evolve under sexual conflict - antagonistic coevolution between genome ...
The X to Autosome Expression Ratio in Haploid
... is apparently tolerated (in haploids). Taken together, our results argue against Ohno’s hypothesis for both haploid and diploid cells and demonstrate that, at least in humans, precise gene regulation for dosage balance, even for members of large protein complexes, are much less critical than is comm ...
... is apparently tolerated (in haploids). Taken together, our results argue against Ohno’s hypothesis for both haploid and diploid cells and demonstrate that, at least in humans, precise gene regulation for dosage balance, even for members of large protein complexes, are much less critical than is comm ...
Epigenetics and the exposomes: Obesity and beyond
... In reproduction, certain genes are turned on while others are turned off in the process of imprinting. In the case of imprinting, even though there are two copies of the gene, only one copy is expressed and there is no substitute functional allele. For this reason, imprinting makes the imprinted gen ...
... In reproduction, certain genes are turned on while others are turned off in the process of imprinting. In the case of imprinting, even though there are two copies of the gene, only one copy is expressed and there is no substitute functional allele. For this reason, imprinting makes the imprinted gen ...
Genomic analysis of gene expression Basics of
... Biological process: A biological process is accomplished by one or more ordered assemblies of molecular functions. Examples of broad biological process terms are cell growth and maintenance or signal transduction. Examples of more specific terms are pyrimidine metabolism or alpha-glucoside transport ...
... Biological process: A biological process is accomplished by one or more ordered assemblies of molecular functions. Examples of broad biological process terms are cell growth and maintenance or signal transduction. Examples of more specific terms are pyrimidine metabolism or alpha-glucoside transport ...
State-of-the-art Biological Processes Enrichment Using Gene Ontology
... a tree) in which each term may be a child of one or more than one parent • The relationships of child to parent can be of the “is a” type or the “part of” type ...
... a tree) in which each term may be a child of one or more than one parent • The relationships of child to parent can be of the “is a” type or the “part of” type ...
No Slide Title
... 2001) with a unique set of parameters and algorithms applied to all chromosome regions (Figure 1A). Its prediction quality has been tested by matching results against a set of experimentally defined full length cDNA as described by Rouzé and collaborators (Pavy et al., 1999). Quality assessment para ...
... 2001) with a unique set of parameters and algorithms applied to all chromosome regions (Figure 1A). Its prediction quality has been tested by matching results against a set of experimentally defined full length cDNA as described by Rouzé and collaborators (Pavy et al., 1999). Quality assessment para ...
Biochemistry
... The controller molecule attaches to the repressor removing it from the operator and transcription proceeds. 1.Structure and catabolite of glucose The molecular mechanisms responsible for the regulation of the genes involved in the metabolism of lactose are now among the best-understood in any organi ...
... The controller molecule attaches to the repressor removing it from the operator and transcription proceeds. 1.Structure and catabolite of glucose The molecular mechanisms responsible for the regulation of the genes involved in the metabolism of lactose are now among the best-understood in any organi ...
Genetic and epigenetic dissection of cis regulatory
... alleles of the expressed gene, whereas cis-acting loci represent genetic polymorphisms in regulatory elements of the expressed gene itself, which lead to steady-state differences in allele-specific expression (ASE) levels. In addition, local chromatin status, mediated through epigenetic modification ...
... alleles of the expressed gene, whereas cis-acting loci represent genetic polymorphisms in regulatory elements of the expressed gene itself, which lead to steady-state differences in allele-specific expression (ASE) levels. In addition, local chromatin status, mediated through epigenetic modification ...
Clinical Next Generation Sequencing (From Bench to Clinitions)
... Next-generation sequencing (NGS) allows for the fast generation of thousands to millions of base pairs of DNA sequence of an individual patient. ...
... Next-generation sequencing (NGS) allows for the fast generation of thousands to millions of base pairs of DNA sequence of an individual patient. ...
Chromatin Structure and Its Effects on Transcription
... Deacetylation of core histones removes binding sites for bromodomain proteins that are essential for transcription activation ...
... Deacetylation of core histones removes binding sites for bromodomain proteins that are essential for transcription activation ...
Leukaemia Section t(2;8)(p23;p11) KAT6A/ASXL2 Atlas of Genetics and Cytogenetics in Oncology and Haematology
... KAT6A is a histone acetyltransferase (HAT). KAT6A has intrinsic HAT activity; KAT6A also forms complexes with MEAF6 (1p34), ING5 (2q37), and BRPF1 (3p25) to acetylate histones H3. KAT6A is a transcriptional co-activator; it interacts with RUNX1 (21q22) and SPI1/PU.1 (11p11) to regulate the expressio ...
... KAT6A is a histone acetyltransferase (HAT). KAT6A has intrinsic HAT activity; KAT6A also forms complexes with MEAF6 (1p34), ING5 (2q37), and BRPF1 (3p25) to acetylate histones H3. KAT6A is a transcriptional co-activator; it interacts with RUNX1 (21q22) and SPI1/PU.1 (11p11) to regulate the expressio ...
A Short Guide to the Human Genome
... The figures in this section were generated from the table of repeats annotated onto release 36.2 of the reference genome sequence. All entries with names beginning with L1 were collected. Because of the methods used during the annotation process, adjacent or overlapping segments may have related ann ...
... The figures in this section were generated from the table of repeats annotated onto release 36.2 of the reference genome sequence. All entries with names beginning with L1 were collected. Because of the methods used during the annotation process, adjacent or overlapping segments may have related ann ...
Identifying Stage-Specific Genes by Combining
... were strongly up-regulated in the sporozoite and gametocyte stages using data generated from both synchronization procedures. As shown in Tables 1 and 2, both synchronizations yielded similar results. Furthermore, the majority of genes were identified in both synchronization datasets. Table 1 shows ...
... were strongly up-regulated in the sporozoite and gametocyte stages using data generated from both synchronization procedures. As shown in Tables 1 and 2, both synchronizations yielded similar results. Furthermore, the majority of genes were identified in both synchronization datasets. Table 1 shows ...
first of Chapter 11: Gene Regulation
... lac operon model • 2 kinds of genes: structural, regulatory elements. • Polycistronic structural genes, with promoter and operator constitute the lac operon. • Promoter mutants make no lac mRNA. • lacI gene makes a repressor, which binds to the operator. • When operator is ‘repressed’ no transcript ...
... lac operon model • 2 kinds of genes: structural, regulatory elements. • Polycistronic structural genes, with promoter and operator constitute the lac operon. • Promoter mutants make no lac mRNA. • lacI gene makes a repressor, which binds to the operator. • When operator is ‘repressed’ no transcript ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) ISSN: 2278-3008.
... Department of Biochemistry, Quaid-i-Azam University Islamabad, Pakistan. Department of Bioinformatics and Biotechnology, International Islamic University, Islamabad, Pakistan. ...
... Department of Biochemistry, Quaid-i-Azam University Islamabad, Pakistan. Department of Bioinformatics and Biotechnology, International Islamic University, Islamabad, Pakistan. ...
Omics and Overview tutorial script
... Genes in the outer ring batched by having exactly the same regulators as each ...
... Genes in the outer ring batched by having exactly the same regulators as each ...
copy number variation, methylation and coregulation in nfkb
... Most of the studied genes that are constitutively upregulated in celiac disease belong to the core of the NFkB route and disruption of coexpression is a relevant feature of the active celiac gut. a) Constitutively overexpressed genes show physical interactions among them and are part of the core of ...
... Most of the studied genes that are constitutively upregulated in celiac disease belong to the core of the NFkB route and disruption of coexpression is a relevant feature of the active celiac gut. a) Constitutively overexpressed genes show physical interactions among them and are part of the core of ...
(CH11) Transcription In Eukaryotes (Slides)
... • The whole process may take hours, or in some cases, months for developmentally regulated genes. • Gene expression can be controlled at many different levels. ...
... • The whole process may take hours, or in some cases, months for developmentally regulated genes. • Gene expression can be controlled at many different levels. ...
Lack of RHCE-Encoded Proteins in the D
... studied by Huang et al.' but our results are different. because we ascertained that this D-- gene complex most likely resulted from a homologous recombination event between RHD and RHCE genes. as indicated by sequence analysis and by a reverse transcriptasepolymerase chain reaction (RT-PCR) assay th ...
... studied by Huang et al.' but our results are different. because we ascertained that this D-- gene complex most likely resulted from a homologous recombination event between RHD and RHCE genes. as indicated by sequence analysis and by a reverse transcriptasepolymerase chain reaction (RT-PCR) assay th ...
Lec-Functional Annotation and Functional Enrichment2010
... entities (molecules or complexes) that perform the actions, and do not specify where or when, or in what context, the action takes place. Molecular functions generally correspond to activities that can be performed by individual gene products, but some activities are performed by assembled complexes ...
... entities (molecules or complexes) that perform the actions, and do not specify where or when, or in what context, the action takes place. Molecular functions generally correspond to activities that can be performed by individual gene products, but some activities are performed by assembled complexes ...
HL Protein Synthesis Question Sheet
... prevent this. The average lifespan of a eukaryotic mRNA molecule is 10 minutes. In eukaryotes, some of the DNA does not code for polypeptides. Some of these non-coding regions can be found within coding regions, breaking up the code. They are called introns. These non-coding introns are transcribed ...
... prevent this. The average lifespan of a eukaryotic mRNA molecule is 10 minutes. In eukaryotes, some of the DNA does not code for polypeptides. Some of these non-coding regions can be found within coding regions, breaking up the code. They are called introns. These non-coding introns are transcribed ...