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Lec-Functional Annotation and Functional Enrichment2010
Lec-Functional Annotation and Functional Enrichment2010

... entities (molecules or complexes) that perform the actions, and do not specify where or when, or in what context, the action takes place. Molecular functions generally correspond to activities that can be performed by individual gene products, but some activities are performed by assembled complexes ...
HL Protein Synthesis Question Sheet
HL Protein Synthesis Question Sheet

... prevent this. The average lifespan of a eukaryotic mRNA molecule is 10 minutes. In eukaryotes, some of the DNA does not code for polypeptides. Some of these non-coding regions can be found within coding regions, breaking up the code. They are called introns. These non-coding introns are transcribed ...
Diapositiva 1
Diapositiva 1

Gene Section SLC16A1 (solute carrier family 16, member 1
Gene Section SLC16A1 (solute carrier family 16, member 1

... 610A-G transition (resulting in a lys204-to-glu (K204E) substitution in a highly conserved residue) and 1414G-A transition (resulting in a gly472-to-arg (G472R) substitution halfway along the cytoplasmic Cterminal chain). These substitutions are not conserved, but were not identified in 90 healthy c ...
Evi3 - Blood Journal
Evi3 - Blood Journal

... the power of retroviral insertional mutagenesis for cancer gene identification in the postgenome era and suggest that retroviral insertional mutagenesis might be useful for identifying cancer genes that are not easy to identify directly in humans. One of the CISs identified in AKXD tumors is Evi3 (e ...
Chapter 18 Gene Expression and Protein Synthesis
Chapter 18 Gene Expression and Protein Synthesis

... • A regulatory gene that controls transcription; the regulatory gene is not transcribed but has control elements, one of which is the promoter. A promoter is unique to each gene. • There is always a sequence of bases on the DNA strand called an initiation signal. • Promoters also contain consensus s ...
Comment - The Journal of Cell Biology
Comment - The Journal of Cell Biology

... number of calcium-regulated signaling molecules were downregulated, potentially providing new insights into pathways affected by the altered calcium homeostasis that results from ruptures in the sarcolemma membrane. Perhaps more importantly, a number of novel observations were apparent that should i ...
Vibrio Cholera
Vibrio Cholera

... chromosome one carries two bacteriophages. ONE VIRUS is called the V. cholera pathogenicity island phage (VPI), which infects and inserts its DNA into the bacterial chromosome and allows the synthesis of a pilus which the bacteria uses to attach to the host intestine SECOND VIRUS is called the chole ...
Tool box for studying gene function in neural development
Tool box for studying gene function in neural development

From DNA to Protein: Genotype to Phenotype Reading Assignments
From DNA to Protein: Genotype to Phenotype Reading Assignments

... • RNA differs from DNA in three ways: It is singlesingle-stranded, its sugar molecule is ribose rather than deoxyribose, deoxyribose, and its fourth base is uracil rather than thymine. • The central dogma of molecular biology is DNA → RNA → protein. Unidirectional when genes are expressed. ...
Slides Part 2 PPTX
Slides Part 2 PPTX

Chapter 14: Gene Transcription and RNA Modification
Chapter 14: Gene Transcription and RNA Modification

... _____ 6. Removes the introns from the pre-mRNA. _____ 7. May produce an mRNA with different combinations of introns. _____ 8. Identifies the consensus sequence AAUAAA in the pre-mRNA. _____ 9. Attaches a guanosine monophosphate to the pre-mRNA. For questions 10 to 14, identify the type of splicing t ...
Human Inheritance
Human Inheritance

... ◦ Smile dimples – Draw a Punnett Square that shows a cross between two heterozygotes for smile dimples ...
Biol/Chem 473 See web site for Reading Assignment for next week`s
Biol/Chem 473 See web site for Reading Assignment for next week`s

... (purple) axial regions, the anterior boundary of expression of the Hoxc6 gene lies at the cervical-thoracic transition o the anterior boundary of the Hox c8 gene lies within the thorax o the Hoxa,b,c9 boundary lies at the thoracic-lumbar transition the vertebral column of snakes does not have a clea ...
Maternal effect genes
Maternal effect genes

Slide 1
Slide 1

... Consensus Coding Sequence (CCDS) set are imported directly and not altered by the genebuild process. • In addition, where manual curation is available for a transcript, the Ensembl and HAVANA transcript models are compared. • The Ensembl and HAVANA models are merged when they agree on the same codin ...
Genomic structure and promoter analysis of pathogen-induced genes from
Genomic structure and promoter analysis of pathogen-induced genes from

... less luciferase activity than the full-length construct A (−738/+464), suggesting that one or various elements important for promoter activity are located in this region. Activity of construct C (+253/+464), that only contained the major part of the intronic region of the 5′-UTR sequence but missing ...
Genome Annotation
Genome Annotation

Gene to Protein
Gene to Protein

Tasmanian Devil gene annotation methods
Tasmanian Devil gene annotation methods

... Targeted Stage: Generating coding models from devil evidence Devil protein sequences were downloaded from public databases (UniProt SwissProt/TrEMBL [8] and Genbank) and filtered to remove sequences based on predictions. The devil sequences were mapped to the genome using Pmatch as indicated in Figu ...
Dimerization of GT element interferes negatively with gene activation
Dimerization of GT element interferes negatively with gene activation

... transcript level (Gilmartin and Chua 1990), as in the case of rbcS-3A, suggesting critical sequence requirements for the activation of gene expression by the GT elements. However, deletions of 5–7 bp between them do not affect the rbcS-3A transcript level. None of the changes in spacing affects the bi ...
Top Scoring Pair
Top Scoring Pair

PowerPoint Presentation - Chapter 17 From Gene to Protein.
PowerPoint Presentation - Chapter 17 From Gene to Protein.

Supplementary Information (doc 46K)
Supplementary Information (doc 46K)

... mentioned in the text are included for P. xylostella since only uniref90 best hits ...
279 - aaabg
279 - aaabg

... Differential Gene Expression Analyses. Microarray data were processed using Affymetrix® Microarray Suite (MAS 5.0) software during normalisation and making detection calls. After editing based on ‘Absent or Marginal’ detection calls, there were 16936 transcripts for further analyses. All statistical ...
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Long non-coding RNA

Long non-coding RNAs (long ncRNAs, lncRNA) are non-protein coding transcripts longer than 200 nucleotides. This somewhat arbitrary limit distinguishes long ncRNAs from small regulatory RNAs such as microRNAs (miRNAs), short interfering RNAs (siRNAs), Piwi-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs), and other short RNAs.
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