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Gill: Genes Enrichment, Gene Regulation I
Gill: Genes Enrichment, Gene Regulation I

How functions are combined within the ABC model
How functions are combined within the ABC model

... LEAFY is a plant-specific gene No homologues in animal cells A single copy gene in Arabidopsis No protein domains suggesting a biochemical function for the protein. ...
Answers to End-of-Chapter Questions – Brooker et al ARIS site
Answers to End-of-Chapter Questions – Brooker et al ARIS site

... round pollen, 3/16 of the offspring would have red flowers and long pollen and 1/16 of the offspring would have red flowers and round pollen. 3. How did the observed results differ from the predicted results? How did Bateson and Punnett explain the results of this particular cross? Answer: Though al ...
2 points - Triton Science
2 points - Triton Science

... first week of life shapes her pups' epigenomes. • And the epigenetic pattern that mom establishes tends to stay put, even after the pups become adults. • The mothers nurturing can activate the GR gene (unwinds the DNA so the gene is active) so that the pup has an easier time relaxing after stress. ...
Part 3
Part 3

Gene Section
Gene Section

... SMARCA4 conserved domains. Proline rich region, containing more than 25% of proline residues in the aminoacid sequence. HSA and BRK domains, containing motifs that may predict binding to DNA. ATPase/helicase domain, contains motifs present in the DEAD helicases superfamily, a diverse family of prote ...
here
here

... • Clear evidence role synaptic proteins. Indeed, the CPi neurons of midfetal PFC-MSC are among first to form synapsis. • Findings suggest that ASD genes converge at additional time points and brain regions • Small set of hcASD genes: prioritizes specificity over sensitivity • Results important to su ...
EVOLUTIONARY DEVELOPMENT AND THE INSECT BODY PLAN
EVOLUTIONARY DEVELOPMENT AND THE INSECT BODY PLAN

... •  Ubx
from
Artemia
and
Drosophila
both
 demonstrated
similar
suppression
of
the
 development
of
head
structures
in
the
thorax
 of
embryonic
Drosophila
 •  Big
difference:
Drosophila
Ubx
suppressed
all
 embryonic
limb
development
on
thorax,
while
 Artemia
Ubx
only
suppressed
15%
 •  Proposal:
Hexapod ...
Haoyang Zeng, Michela Meister, Subarna Sinha, David L. Dill
Haoyang Zeng, Michela Meister, Subarna Sinha, David L. Dill

... •  Recent work [1] revealed four subtypes of GBM : Classical, Mesenchymal, Proneural and Neural. •  We made up virtual genes of each subtype by evaluating the table in [1] which maps from each sample to subtype. •  Subtype virtual genes revealed the same signature as in [1], which are selectively sh ...
Gene Transcription in Prokaryotes
Gene Transcription in Prokaryotes

... • Single DNA-binding protein may act as either a repressor or an activator – araC protein ...
Supplementary Methods - Clinical Cancer Research
Supplementary Methods - Clinical Cancer Research

File S1
File S1

USMLE Step 1 Web Prep — Transcription and RNA Processing: Part
USMLE Step 1 Web Prep — Transcription and RNA Processing: Part

... inside the nucleus to form the mature mRNA molecule A 7-methylguanosine cap is added to the 5' end while the RNA molecule is still being synthesized. The cap structure serves as a ribosome-binding site and also helps to protect the mRNA chain from degradation. A poly-A tail is attached to the 3' end ...
Chapter 12: Mechanisms and Regulation of Transcription I
Chapter 12: Mechanisms and Regulation of Transcription I

... 5. The transcriptional unit gets transcribed into an RNA and starts its first base pair is noted by +1 B. The Structure Of A Gene: The RNA Polymerase II Core Promoters 1. As we saw, in order for a gene to be transcribed, it must have a promoter 2. In eukaryotes, the minimal amount of promoter sequen ...
Hands on Exercise - Berkeley`s D-Lab
Hands on Exercise - Berkeley`s D-Lab

... c. logFC tells you the magnitude of the gene expression change. It is in log2 scale. So a value of 3.67 is 2 to the power of 3.67 (2^3.67), or ~12 fold. In other words, the levels of gene expression for this gene are 12 times higher in patients than in normal healthy controls. Click on the name of t ...
Gene Section GREB1 (growth regulation by estrogen in breast cancer 1)
Gene Section GREB1 (growth regulation by estrogen in breast cancer 1)

... The GREB1 gene contains a distal enhancer 20 kb upstream of the transcription start site containing 3 estrogen response elements (EREs), which bind estrogen receptor α (ERα) in the presence of estrogen. In breast cancer cells, the steroid receptor co-activator SRC-3, phosphorylated RNA polymerase II ...
Leukemia Section t(17;19)(q22;p13) Atlas of Genetics and Cytogenetics in Oncology and Haematology
Leukemia Section t(17;19)(q22;p13) Atlas of Genetics and Cytogenetics in Oncology and Haematology

... E2A-HLF with altered DNA binding affinity compared with native HLF; it functions as an antiapoptotic transcription factor in leukemic cell transformation; when E2A-HLF protein was introduced into murine pro-B lymphocytes, it reverted both interleukin-3dependent and p53-mediated apoptosis; E2A-HLF co ...
Document
Document

... The regulator matrix R is a subset of D, containing only the rows corresponding to the intergenic region assigned to each regulator, in the same order as the columns of regulators. - Autoregulatory motif: Find each non-zero entry on the diagonal of R. - Feedforward loop: For each master regulator (c ...
Maternal effect genes
Maternal effect genes

... Maternal effect genes • Phenotype of the embryo is determined by the genotype of the mother. • The polarity and spatial coordinates of the embryo are initially set by the products of these genes (therefore, sometimes called “coordinate genes”). • The gene products, either mRNA transcripts, protein ...
Document
Document

... (2) Are all genes expressed in all cells? Explain why or why not. How do scientists study gene expression? ...
Gene Section ENPP2 (ectonucleotide pyrophosphatase/phosphodiesterase 2) Atlas of Genetics and Cytogenetics
Gene Section ENPP2 (ectonucleotide pyrophosphatase/phosphodiesterase 2) Atlas of Genetics and Cytogenetics

... The mRNA for ENPP2 is 3276 bp with exon 12 and 3120 bp without it. The ENPP2 promoter is reported to have four SP1 sites as well as binding sites for NFAT and NF-kappaB but no TATA or CAAT boxes. The only transcription factor that has been proven to increase ENPP2 protein expression is NFATC2/NFAT1, ...
Gene Section NFATC2 (nuclear factor of activated T cells, cytoplasmic, calcineurin
Gene Section NFATC2 (nuclear factor of activated T cells, cytoplasmic, calcineurin

... are two serine rich regions (SRRs) and three SPXXrepeat motifs (SPs), where X stands for any amino acid. Calcineurin and NFAT kinases regulate the activity of the NFAT proteins by determining the phosphorylation status of the serine residues, interacting with NFAT proteins at the NHR. Another, highl ...
l(1)sc
l(1)sc

Genomics - FSU Biology - Florida State University
Genomics - FSU Biology - Florida State University

... content of the DNA itself. Searching by content utilizes the fact that genes necessarily have many implicit biological constraints imposed on their genetic code. This induces certain periodicities and patterns to produce distinctly unique coding sequences; non-coding stretches do not exhibit this ty ...
beyond Mendel - the molecular basis of inheritance
beyond Mendel - the molecular basis of inheritance

... • If genes are completely linked, then expect only parental types in offspring • Crossing over in Prophase I accounts for recombination of linked genes • Genes that are located in the same chromosome close to each other are less likely to separate during synapsis. Genes that are further apart are m ...
< 1 ... 114 115 116 117 118 119 120 121 122 ... 207 >

Long non-coding RNA

Long non-coding RNAs (long ncRNAs, lncRNA) are non-protein coding transcripts longer than 200 nucleotides. This somewhat arbitrary limit distinguishes long ncRNAs from small regulatory RNAs such as microRNAs (miRNAs), short interfering RNAs (siRNAs), Piwi-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs), and other short RNAs.
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