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Goals of pharmacogenomics
Goals of pharmacogenomics

...  Proteome  All proteins in the cell  Larger than the genome  Alternative splicing  Post translational modification  Different proteins are found in different cells  Why proteins  Catalyze chemical reactions  Mount an immunological response to infection  chemical messengers to regulate gro ...
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Biology Test Chapters 13 Name and Honor Code: 1. The insertion of

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Slajd 1

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Epigenomics

Epigenomics is the study of the complete set of epigenetic modifications on the genetic material of a cell, known as the epigenome. The field is analogous to genomics and proteomics, which are the study of the genome and proteome of a cell (Russell 2010 p. 217 & 230). Epigenetic modifications are reversible modifications on a cell’s DNA or histones that affect gene expression without altering the DNA sequence (Russell 2010 p. 475). Two of the most characterized epigenetic modifications are DNA methylation and histone modification. Epigenetic modifications play an important role in gene expression and regulation, and are involved in numerous cellular processes such as in differentiation/development and tumorigenesis (Russell 2010 p. 597). The study of epigenetics on a global level has been made possible only recently through the adaptation of genomic high-throughput assays (Laird 2010) and.
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