Linkage arrangement in the vitellogenin gene family of Xenopus
... The DNA was electrophoresed on a agarose gel along with 3 equivalents per haploid genome of the clones XXlv 107, 110, 221 or 228 or 6 equivalents of the clones XXIv 124 or 126 as where indicated. The DNA fragments were then transferred to a nitrocellulose membrane. The probes used are indicated in F ...
... The DNA was electrophoresed on a agarose gel along with 3 equivalents per haploid genome of the clones XXlv 107, 110, 221 or 228 or 6 equivalents of the clones XXIv 124 or 126 as where indicated. The DNA fragments were then transferred to a nitrocellulose membrane. The probes used are indicated in F ...
Expression and DNA Sequence of the Gene Coding for the lux
... nonfluorescent flavoprotein of unknown function containing a flavin adduct covalently linked with tetradecanoic acid (20). Interestingly, only Photobacterium strains with luxF have another gene, luxL, located approximately 600 bp upstream from the start of the lux operon transcribed in the opposite ...
... nonfluorescent flavoprotein of unknown function containing a flavin adduct covalently linked with tetradecanoic acid (20). Interestingly, only Photobacterium strains with luxF have another gene, luxL, located approximately 600 bp upstream from the start of the lux operon transcribed in the opposite ...
Leukaemia Section t(11;19)(q23;p13.1) Atlas of Genetics and Cytogenetics in Oncology and Haematology
... M4/M5 most often; M1/M2 at times; therapy related AL; however, clonal rearrangements of IgH gene have been found, demonstrating a biphenotypic nature. Epidemiology Children and, most often, adults (7 days to 83 yrs); congenital cases are rare, in contrast with the t(11;19)(q23;p13.3) leukaemia; bala ...
... M4/M5 most often; M1/M2 at times; therapy related AL; however, clonal rearrangements of IgH gene have been found, demonstrating a biphenotypic nature. Epidemiology Children and, most often, adults (7 days to 83 yrs); congenital cases are rare, in contrast with the t(11;19)(q23;p13.3) leukaemia; bala ...
Chromosome Structure
... Introns - May contain genes expressed independently of the exons they fall between. Many introns code for small nuclear RNAs (snoRNAs). These accumulate in the nucleolus, and may play a role in ribosome assembly. Thus the introns cut out of premRNA, may play a role in producing, or regulating produc ...
... Introns - May contain genes expressed independently of the exons they fall between. Many introns code for small nuclear RNAs (snoRNAs). These accumulate in the nucleolus, and may play a role in ribosome assembly. Thus the introns cut out of premRNA, may play a role in producing, or regulating produc ...
Genes Reading Group, Minutes 2. (Nov 13)
... not quite capture the fuzziness Rheinberger keeps talking about. There is a disconnect between the history he recounts and message he wants the history to convey (he is talking fuzziness and then there is integration after integration): things keep getting more and more complex but not necessarily c ...
... not quite capture the fuzziness Rheinberger keeps talking about. There is a disconnect between the history he recounts and message he wants the history to convey (he is talking fuzziness and then there is integration after integration): things keep getting more and more complex but not necessarily c ...
DMD Reviews 85 - Action Duchenne
... for the delivery of large genes’. They note that no other data on this concept have been published and they note that they are currently aiming to optimize the design of these triple trans-splicing vectors further so that the ‘splicing between the three vectors is more efficient and expression of th ...
... for the delivery of large genes’. They note that no other data on this concept have been published and they note that they are currently aiming to optimize the design of these triple trans-splicing vectors further so that the ‘splicing between the three vectors is more efficient and expression of th ...
Analysis of Transcription Initiation in the Panolisflammea Nuclear
... hybridization analyses (Smith & Summers, 1982), they do show similarity at the nucleotide and amino acid level when sequence data are compared (Rohrmann, 1986). In this same study a 12 nucleotide consensus was highlighted at the 5' end of all the polyhedrin and granulin genes which had been sequence ...
... hybridization analyses (Smith & Summers, 1982), they do show similarity at the nucleotide and amino acid level when sequence data are compared (Rohrmann, 1986). In this same study a 12 nucleotide consensus was highlighted at the 5' end of all the polyhedrin and granulin genes which had been sequence ...
PDF
... marsupials and eutherians. These genes encode proteins that are homologous to a retrotransposon Gag capsid protein and sometimes also have a Pol-like region. We previously demonstrated that PEG10 (SIRH1) and PEG11/RTL1 (SIRH2) play essential but different roles in placental development. PEG10 is con ...
... marsupials and eutherians. These genes encode proteins that are homologous to a retrotransposon Gag capsid protein and sometimes also have a Pol-like region. We previously demonstrated that PEG10 (SIRH1) and PEG11/RTL1 (SIRH2) play essential but different roles in placental development. PEG10 is con ...
Leukaemia Section t(5;11)(q35;q12) NSD1/FEN1 Atlas of Genetics and Cytogenetics in Oncology and Haematology
... The FEN1 gene contains 2 exons, of which a sole is coding, spanning 4 kb (Hiraoka et al., 1995). Protein The protein has 380 amino acids and localizes to the nucleus. It is a structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair ...
... The FEN1 gene contains 2 exons, of which a sole is coding, spanning 4 kb (Hiraoka et al., 1995). Protein The protein has 380 amino acids and localizes to the nucleus. It is a structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair ...
Slide 1
... Neuroscience Centre, Institute of Cell and Molecular Sciences Barts and The London School of Medicine and Dentistry Queen Mary University of London ...
... Neuroscience Centre, Institute of Cell and Molecular Sciences Barts and The London School of Medicine and Dentistry Queen Mary University of London ...
Developmental Psychobiology - Champagne Lab
... have clearly demonstrated that there must be other parentof-origin mechanisms at play. For instance, reciprocal hybrid mice produced from mating either C57BL/6 and CBA/Ca strains or C57BL/6 and DBA strains were found to avoid the urine of their genetic maternal strain in an odor preference test even ...
... have clearly demonstrated that there must be other parentof-origin mechanisms at play. For instance, reciprocal hybrid mice produced from mating either C57BL/6 and CBA/Ca strains or C57BL/6 and DBA strains were found to avoid the urine of their genetic maternal strain in an odor preference test even ...
DNA level results in a phenotype of the patient
... phenotypes. Another study by (Ho et al. 2004) showed decreased expression of MBNL1 in cultured cells caused aberrant splicing in both the cardiac troponin T (cTNT) and insulin receptor (IR) genes, which is consistent with DM1 individuals. While there is much evidence supporting MBNL1 sequestration a ...
... phenotypes. Another study by (Ho et al. 2004) showed decreased expression of MBNL1 in cultured cells caused aberrant splicing in both the cardiac troponin T (cTNT) and insulin receptor (IR) genes, which is consistent with DM1 individuals. While there is much evidence supporting MBNL1 sequestration a ...
DmTTF, a novel mitochondrial transcription termination factor that
... termination factor. FlyBase GadFly Genome Annotation Database reports that the DmTTF gene is 1587 bp long; it is composed of three exons and two introns and generates a transcript of 1468 nt. The cDNA of DmTTF was cloned by means of PCR on a cDNA library of D.melanogaster. The sequence of the ORF (a ...
... termination factor. FlyBase GadFly Genome Annotation Database reports that the DmTTF gene is 1587 bp long; it is composed of three exons and two introns and generates a transcript of 1468 nt. The cDNA of DmTTF was cloned by means of PCR on a cDNA library of D.melanogaster. The sequence of the ORF (a ...
Improving bone properties and fracture susceptibility: experimental
... exercise). Because fractures are caused by a number of different factors, reducing fracture incidence requires a multifactorial approach to unraveling the underlying biology of bone metabolism, in order to discover new ways to improve bone properties and prevent fractures. We have taken such an appr ...
... exercise). Because fractures are caused by a number of different factors, reducing fracture incidence requires a multifactorial approach to unraveling the underlying biology of bone metabolism, in order to discover new ways to improve bone properties and prevent fractures. We have taken such an appr ...
Epigenetic Signatures of AutismTrimethylated
... From: Epigenetic Signatures of AutismTrimethylated H3K4 Landscapes in Prefrontal Neurons Arch Gen Psychiatry. 2012;69(3):314-324. doi:10.1001/archgenpsychiatry.2011.151 ...
... From: Epigenetic Signatures of AutismTrimethylated H3K4 Landscapes in Prefrontal Neurons Arch Gen Psychiatry. 2012;69(3):314-324. doi:10.1001/archgenpsychiatry.2011.151 ...
Are all genes regulatory genes?
... nucleus to the cytoplasm. Such precursor-microRNAs can originate, for example, from specifically transcribed DNA segments with own promoters or from introns of spliced protein-coding genes. Exploiting the base-pairing capabilities of these single-stranded microRNAs, the RNA-induced silencing complex ...
... nucleus to the cytoplasm. Such precursor-microRNAs can originate, for example, from specifically transcribed DNA segments with own promoters or from introns of spliced protein-coding genes. Exploiting the base-pairing capabilities of these single-stranded microRNAs, the RNA-induced silencing complex ...
Chpt19_TxnlRegEuk.doc
... 2. Example: GAL4 a. After induction with galactose, the GAL4 protein will stimulate expression of genes in the GAL regulon of yeast, which encodes the enzymes that catalyze entry of galactose into intermediary metabolism. E.g. GAL1 encodes galactokinase, which converts the substrate to galactose-1-p ...
... 2. Example: GAL4 a. After induction with galactose, the GAL4 protein will stimulate expression of genes in the GAL regulon of yeast, which encodes the enzymes that catalyze entry of galactose into intermediary metabolism. E.g. GAL1 encodes galactokinase, which converts the substrate to galactose-1-p ...
Bacteriophage-mediated nucleic acid immunisation
... clone was selected from the MmmSC library by performing plaque lifts and Western blotting with bovine convalescent and rabbit hyperimmune serum raised against MmmSC. Plaques which showed good responses against both sera were picked, ampli¢ed and stored. This selection was possible since insert genes ...
... clone was selected from the MmmSC library by performing plaque lifts and Western blotting with bovine convalescent and rabbit hyperimmune serum raised against MmmSC. Plaques which showed good responses against both sera were picked, ampli¢ed and stored. This selection was possible since insert genes ...
Welcome to the Gene and Allele Database Tutorial
... Associated Data is under the Gene detail. The number represent numbers of associations. Click a category to expand the table and access that data in Gramene (see slides 8–13). Grayed-out categories have no associations. ...
... Associated Data is under the Gene detail. The number represent numbers of associations. Click a category to expand the table and access that data in Gramene (see slides 8–13). Grayed-out categories have no associations. ...
Gene Section MLL (myeloid/lymphoid or mixed lineage leukemia) Atlas of Genetics and Cytogenetics
... t(9;11)(p22;q23)/ANLL → MLL/AF9 Disease M5/M4 de novo and therapy related ANLL. Prognosis The prognosis may not be as poor as in other 11q23 leukaemias in de novo cases; very poor prognosis in secondary ANLL cases. Cytogenetics May be overlooked; often as a sole anomaly. Hybrid/Mutated Gene Variable ...
... t(9;11)(p22;q23)/ANLL → MLL/AF9 Disease M5/M4 de novo and therapy related ANLL. Prognosis The prognosis may not be as poor as in other 11q23 leukaemias in de novo cases; very poor prognosis in secondary ANLL cases. Cytogenetics May be overlooked; often as a sole anomaly. Hybrid/Mutated Gene Variable ...
Full Text - Genes | Genomes | Genetics
... fully resolved. In Drosophila, upSETe00365/e00365 flies were described to be viable, but with a female fertility defect due to derepression of transposable elements in the ovary (Rincon-Arano et al. 2012). We previously identified the UpSET protein (CG9007) as a top interactor with the MSL3 protein by ...
... fully resolved. In Drosophila, upSETe00365/e00365 flies were described to be viable, but with a female fertility defect due to derepression of transposable elements in the ovary (Rincon-Arano et al. 2012). We previously identified the UpSET protein (CG9007) as a top interactor with the MSL3 protein by ...
Acute stress and hippocampal histone H3 lysine 9 trimethylation, a
... but it was associated with reductions (stress down) at only 1,438 loci (Fig. 3A) [false-discovery rate (FDR) <0.0001, P < 0.05]. When categorized by repetitive-element class, differences emerge in the enrichment of stress-up versus stress-down peaks: the autonomous long interspersed element (LINE) r ...
... but it was associated with reductions (stress down) at only 1,438 loci (Fig. 3A) [false-discovery rate (FDR) <0.0001, P < 0.05]. When categorized by repetitive-element class, differences emerge in the enrichment of stress-up versus stress-down peaks: the autonomous long interspersed element (LINE) r ...
2011 CSH - Harvard University
... factors may require the recruitment of chromatin-modifying enzymes to their target gene promoters prior to making these genes competent for stimulus-regulated transcription (Hargreaves et al. 2009). Finally, a late wave of gene transcription is mediated by induced expression of immediate-early gene ...
... factors may require the recruitment of chromatin-modifying enzymes to their target gene promoters prior to making these genes competent for stimulus-regulated transcription (Hargreaves et al. 2009). Finally, a late wave of gene transcription is mediated by induced expression of immediate-early gene ...
Example Presentation
... •Adult leaves have an elongated petiole/midrib similar to PHAN mutants in Antirrhinum. •The vascular system is cylindrical but a dorsal rib is present in a normal position. ...
... •Adult leaves have an elongated petiole/midrib similar to PHAN mutants in Antirrhinum. •The vascular system is cylindrical but a dorsal rib is present in a normal position. ...