AML1-ETO expression is directly involved in the development of
... Result conDetection of AML1-ETO expression in the spleen and bone marrow cells from transgenic mice without ENU treatment (Tg), leukemic transgenic mice (Tg -ENU-AML or Tg-ENU-ALL), and wild-type (WT) mice. Representative results are shown. Kasumi-1 cell line RNA was used as a positive control. (A) ...
... Result conDetection of AML1-ETO expression in the spleen and bone marrow cells from transgenic mice without ENU treatment (Tg), leukemic transgenic mice (Tg -ENU-AML or Tg-ENU-ALL), and wild-type (WT) mice. Representative results are shown. Kasumi-1 cell line RNA was used as a positive control. (A) ...
Response to Nelson-Sathi et al. (Nature 517, 77-80
... Number of gene gains at the origin of archaeal phyla ...
... Number of gene gains at the origin of archaeal phyla ...
Systems memory consolidation in Drosophila
... to be acquired, encoded, stored, maintained and retrieved. As time passes after training, memories become less easily retrieved, but also become progressively more stable in the face of experimental perturbations. This process is referred to as consolidation. But the term has been used to describe t ...
... to be acquired, encoded, stored, maintained and retrieved. As time passes after training, memories become less easily retrieved, but also become progressively more stable in the face of experimental perturbations. This process is referred to as consolidation. But the term has been used to describe t ...
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... TA-5´ (b) 4 (c) ClaI: cannot be determined; TaqI: yes 5. A new restriction enzyme is discovered that recognizes an 8-base restriction sequence. About how many fragments of the Wombat genome (approximately 4.2 × 108 in size) would you expect if you digested it with this enzyme? Answer: An 8-base reco ...
... TA-5´ (b) 4 (c) ClaI: cannot be determined; TaqI: yes 5. A new restriction enzyme is discovered that recognizes an 8-base restriction sequence. About how many fragments of the Wombat genome (approximately 4.2 × 108 in size) would you expect if you digested it with this enzyme? Answer: An 8-base reco ...
279 - aaabg
... Microarray Suite (MAS 5.0) software during normalisation and making detection calls. After editing based on ‘Absent or Marginal’ detection calls, there were 16936 transcripts for further analyses. All statistical and bioinformatic analyses were performed using the Bioconductor package, limma (v.2.10 ...
... Microarray Suite (MAS 5.0) software during normalisation and making detection calls. After editing based on ‘Absent or Marginal’ detection calls, there were 16936 transcripts for further analyses. All statistical and bioinformatic analyses were performed using the Bioconductor package, limma (v.2.10 ...
This article was originally published in a journal published by
... website or repository, are prohibited. For exceptions, permission may be sought for such use through Elsevier’s permissions site at: http://www.elsevier.com/locate/permissionusematerial ...
... website or repository, are prohibited. For exceptions, permission may be sought for such use through Elsevier’s permissions site at: http://www.elsevier.com/locate/permissionusematerial ...
Transcriptional Repression of Hox Genes by C. elegans HP1/HPL
... play central roles in the formation of higher-order chromatin structure and gene expression. Recent studies have shown a physical interaction between H1 and HP1; however, the biological role of histone H1 and HP1 is not well understood. Additionally, the function of HP1 and H1 isoform interactions i ...
... play central roles in the formation of higher-order chromatin structure and gene expression. Recent studies have shown a physical interaction between H1 and HP1; however, the biological role of histone H1 and HP1 is not well understood. Additionally, the function of HP1 and H1 isoform interactions i ...
Genes and addiction
... Other aspects of drug exposure have been studied in genetic models. For example, withdrawal symptoms have been used as a measure of opiate dependence on many occasions29. The aversive (negative emotional) effects of drug withdrawal can be measured by conditioned place-avoidance assays, in which anim ...
... Other aspects of drug exposure have been studied in genetic models. For example, withdrawal symptoms have been used as a measure of opiate dependence on many occasions29. The aversive (negative emotional) effects of drug withdrawal can be measured by conditioned place-avoidance assays, in which anim ...
File
... to the principle of linkage. After identifying more than 50 Drosophila genes, Morgan discovered that many of them appeared to be “linked” together in ways that, at first glance, seemed to violate the principle of independent assortment. For example, a fly with reddish-orange eyes and miniature wings ...
... to the principle of linkage. After identifying more than 50 Drosophila genes, Morgan discovered that many of them appeared to be “linked” together in ways that, at first glance, seemed to violate the principle of independent assortment. For example, a fly with reddish-orange eyes and miniature wings ...
Three Dimensional Organization of Genome Might Have Guided the
... In eukaryotes, genes are nonrandomly organized into short gene-dense regions or “gene-clusters” interspersed by long gene-poor regions. How these gene-clusters have evolved is not entirely clear. Gene duplication may not account for all the gene-clusters since the genes in most of the clusters do no ...
... In eukaryotes, genes are nonrandomly organized into short gene-dense regions or “gene-clusters” interspersed by long gene-poor regions. How these gene-clusters have evolved is not entirely clear. Gene duplication may not account for all the gene-clusters since the genes in most of the clusters do no ...
Quiz 9 BIol203 Fall 2013ppt
... Arl is a transcription factor and thus must get into the nucleus to function. However, the nuclear localization sequence is NOT located on exon 1, exon 2, or exon 4. 4pts. Circle the portion of the above gene that you would use to make a transgene that expresses Arl in the leg only. 4pts. Mark with ...
... Arl is a transcription factor and thus must get into the nucleus to function. However, the nuclear localization sequence is NOT located on exon 1, exon 2, or exon 4. 4pts. Circle the portion of the above gene that you would use to make a transgene that expresses Arl in the leg only. 4pts. Mark with ...
Chapter 17
... DNA fingerprints have played central roles in many recent rape and murder trials. What is a DNA fingerprint? What roles do DNA prints play in these forensic cases? In some cases, geneticists have been concerned that DNA fingerprint data were being used improperly. What were some of their concerns, a ...
... DNA fingerprints have played central roles in many recent rape and murder trials. What is a DNA fingerprint? What roles do DNA prints play in these forensic cases? In some cases, geneticists have been concerned that DNA fingerprint data were being used improperly. What were some of their concerns, a ...
Inquiry into Life Twelfth Edition
... • High levels of repressor can repress transcription from PRM – Process may involve interaction of repressor dimers bound to OR1, OR2, and OR3 – Repressor dimers bound to OL1, OL2, and OL3 via ...
... • High levels of repressor can repress transcription from PRM – Process may involve interaction of repressor dimers bound to OR1, OR2, and OR3 – Repressor dimers bound to OL1, OL2, and OL3 via ...
MCDB 1041 3/15/13 Working with DNA and Biotechnology Part I
... Pst factors I A fragment of DNA containingCa promoter GLU that is only bound by transcription in the ...
... Pst factors I A fragment of DNA containingCa promoter GLU that is only bound by transcription in the ...
Non-coding RNAs are widely distributed in the 3 life domains
... CsrA and CsrA homolog RsmA and effect of sequestration by sRNA(A) Gene expression is controlled by CsrA binding to leader segments of target mRNAs (e.g. pgaABCD involved in PGA biosynthesis and export) affecting their translation and stability. CsrA activity is repressed via sequestration of CsrA b ...
... CsrA and CsrA homolog RsmA and effect of sequestration by sRNA(A) Gene expression is controlled by CsrA binding to leader segments of target mRNAs (e.g. pgaABCD involved in PGA biosynthesis and export) affecting their translation and stability. CsrA activity is repressed via sequestration of CsrA b ...
2015 department of medicine research day
... Background and Aims: Liver fibrosis, characterized by excess deposition of collagen within the hepatic parenchyma, is a multifactorial trait that develops in response to all types of chronic liver injury, including fatty liver (NAFLD/NASH), viral hepatitis (B & C), and alcohol abuse. The Hybrid Mous ...
... Background and Aims: Liver fibrosis, characterized by excess deposition of collagen within the hepatic parenchyma, is a multifactorial trait that develops in response to all types of chronic liver injury, including fatty liver (NAFLD/NASH), viral hepatitis (B & C), and alcohol abuse. The Hybrid Mous ...
Supporting Online Material
... Figure S9. Scheme of crossing for silencing of dUTPase in the dorsal compartment of Drosophila wing imaginal discs. Crossing scheme is shown on panel (A): virgin females of the MS1096 Gal4 enhancer trap line expressing Gal4 preferentially in the dorsal compartment of the wing and carrying UAS-Dicer2 ...
... Figure S9. Scheme of crossing for silencing of dUTPase in the dorsal compartment of Drosophila wing imaginal discs. Crossing scheme is shown on panel (A): virgin females of the MS1096 Gal4 enhancer trap line expressing Gal4 preferentially in the dorsal compartment of the wing and carrying UAS-Dicer2 ...
How Genes and Genomes Evolve
... • Adult mammalian females are genetic mosaics (with different alleles functioning in different cells) – A. This is true since paternal & maternal X chromosomes may have different alleles for same trait – B. X-linked pigment genes in cats – calico – C. Pigmentation genes in humans are not found on X ...
... • Adult mammalian females are genetic mosaics (with different alleles functioning in different cells) – A. This is true since paternal & maternal X chromosomes may have different alleles for same trait – B. X-linked pigment genes in cats – calico – C. Pigmentation genes in humans are not found on X ...
ab initio and Evidence-Based Gene Finding
... Ab initio gene prediction Ab initio = from the beginning Predict genes using only the genomic DNA sequence Search for signals of protein coding regions Based on a probabilistic model Hidden Markov Models (HMM) Support Vector Machines (SVM) ...
... Ab initio gene prediction Ab initio = from the beginning Predict genes using only the genomic DNA sequence Search for signals of protein coding regions Based on a probabilistic model Hidden Markov Models (HMM) Support Vector Machines (SVM) ...
Illumina Infinium HumanMethylation450 BeadChip Data
... powerful embedded statistics and visualizations to yield deep biological interpretation. Going from raw data to biological interpretation has never been easier. ...
... powerful embedded statistics and visualizations to yield deep biological interpretation. Going from raw data to biological interpretation has never been easier. ...
File
... 9. In genome mapping, the most general procedure uses the following methods: RFLP mapping (R), FISH (F), DNA sequencing (S), and physical mapping (P). Which of the following is the most appropriate order of these techniques? * A) RFPS B) PSRF C) SRFP D) FRPS E) PRFS 10. A minisatellite marker band p ...
... 9. In genome mapping, the most general procedure uses the following methods: RFLP mapping (R), FISH (F), DNA sequencing (S), and physical mapping (P). Which of the following is the most appropriate order of these techniques? * A) RFPS B) PSRF C) SRFP D) FRPS E) PRFS 10. A minisatellite marker band p ...
Genetics of Quantitative Variation in Human Gene Expression
... The extent of variation among individuals at the DNA sequence level has been well characterized. The goal of many genetic studies is to determine the consequences of these sequence variants, for both normal and disease phenotypes. We have extended the study of genome variation from the sequence to m ...
... The extent of variation among individuals at the DNA sequence level has been well characterized. The goal of many genetic studies is to determine the consequences of these sequence variants, for both normal and disease phenotypes. We have extended the study of genome variation from the sequence to m ...
File - Joris Vangeneugden
... combined symptomatology is referred to as post-traumatic stress disorder, which has a lifetime prevalence of 5-8% globally (Kessler et al., 2005) and up to 35% in post-war countries (Priebe et al., 2010). Although not everybody experiencing the same traumatic event will eventually develop PTSD, conv ...
... combined symptomatology is referred to as post-traumatic stress disorder, which has a lifetime prevalence of 5-8% globally (Kessler et al., 2005) and up to 35% in post-war countries (Priebe et al., 2010). Although not everybody experiencing the same traumatic event will eventually develop PTSD, conv ...
Differential Roles of the Frontal Cortex, Basal Ganglia, and
... true only for the hyperset that had been learned. The likelihood of anticipatory saccade increased gradually over 20–30 days of practice of the particular hyperset. The time course was similar to that for the hand sequence. Another feature of skill learning is that the skill is maintained for a long ...
... true only for the hyperset that had been learned. The likelihood of anticipatory saccade increased gradually over 20–30 days of practice of the particular hyperset. The time course was similar to that for the hand sequence. Another feature of skill learning is that the skill is maintained for a long ...
A Brief History of Memory and Aging
... memory. Contrary to Socrates’ dismissal of the art of writing, Confucius felt that it was a very useful memory aid: “The palest ink is better than the best memory.” Moving forward in time we come to Aristotle (384–322 BCE), who is a favorite of memory researchers because he wrote a treatise specific ...
... memory. Contrary to Socrates’ dismissal of the art of writing, Confucius felt that it was a very useful memory aid: “The palest ink is better than the best memory.” Moving forward in time we come to Aristotle (384–322 BCE), who is a favorite of memory researchers because he wrote a treatise specific ...