The Frontal Cortex and Working with Memory
... then turned off while the rats waited the prescribed delay period for the levers to reappear. There was no difference between hippocampus-lesioned and control groups in learning the conditional rule in the 0-delay condition, but the group with FC lesions improved at a much slower rate and, as can be ...
... then turned off while the rats waited the prescribed delay period for the levers to reappear. There was no difference between hippocampus-lesioned and control groups in learning the conditional rule in the 0-delay condition, but the group with FC lesions improved at a much slower rate and, as can be ...
Chapter 6: Gene Expression
... information in the form of a nucleotide sequence is converted to an amino acid sequence of a protein. Researchers identified four nucleotides in RNA (A, U, G, and C) and 20 amino acids. Mathematically, there could not be a oneto-one relationship between nucleotides and amino acids, nor could there b ...
... information in the form of a nucleotide sequence is converted to an amino acid sequence of a protein. Researchers identified four nucleotides in RNA (A, U, G, and C) and 20 amino acids. Mathematically, there could not be a oneto-one relationship between nucleotides and amino acids, nor could there b ...
Synaptic reverberation underlying mnemonic persistent activity
... Fig. I. Three types of working memory encoding. (a) Discrete working memory. In a delayed match (M)-to-sample (S) experiment, an inferotemporal neuron shows sustained high activity for the color red (but not green) of a visual cue, during a delay period of 16 s. Redrawn, with permission, from Fuster ...
... Fig. I. Three types of working memory encoding. (a) Discrete working memory. In a delayed match (M)-to-sample (S) experiment, an inferotemporal neuron shows sustained high activity for the color red (but not green) of a visual cue, during a delay period of 16 s. Redrawn, with permission, from Fuster ...
Eukaryotic RNA Polymerases and their Promoters
... – Spacing between these elements is important ...
... – Spacing between these elements is important ...
DNA repair disorders
... of its mutational load by free radical production. A wide variety of other DNA damaging agents, both natural and man made, are known, many are used as chemotherapeutic agents. DNA repair The DNA double helix seems to have evolved so that mutations, even as small as individual base damage, are easily ...
... of its mutational load by free radical production. A wide variety of other DNA damaging agents, both natural and man made, are known, many are used as chemotherapeutic agents. DNA repair The DNA double helix seems to have evolved so that mutations, even as small as individual base damage, are easily ...
Challenge Problems 2 - AHS
... products. AaBb and aabb are our minor/mutated products. (They resulted from crossing over.) To ...
... products. AaBb and aabb are our minor/mutated products. (They resulted from crossing over.) To ...
Journal of Advanced Computing (2012) 1
... node knowledge was derived from the three GO ontologies (GO molecular function ontology, GO biological process ontology, and GO cellular component ontology). When evaluated on 19 diseases for which we derived root node sets, KNGP using both link and node knowledge performed better that using only li ...
... node knowledge was derived from the three GO ontologies (GO molecular function ontology, GO biological process ontology, and GO cellular component ontology). When evaluated on 19 diseases for which we derived root node sets, KNGP using both link and node knowledge performed better that using only li ...
Gene Section TTL (twelve-thirteen translocation leukemia) Atlas of Genetics and Cytogenetics
... Three splicing forms, namely: TTL-T, TTL-B1 and B2. TTL-T is 2090 bp long and composed of exons 1-8. The longest open-reading frame contains exons 4, 5, and part of exon 6; it encods a 133 amino acids peptid. TTL-B1 transcript is 3450 bp long and is composed of exons 4, 5, and part of exon 9. TTL-B2 ...
... Three splicing forms, namely: TTL-T, TTL-B1 and B2. TTL-T is 2090 bp long and composed of exons 1-8. The longest open-reading frame contains exons 4, 5, and part of exon 6; it encods a 133 amino acids peptid. TTL-B1 transcript is 3450 bp long and is composed of exons 4, 5, and part of exon 9. TTL-B2 ...
learning, Memory, and Cognition: Animal Perspectives
... typy are two close strategies and are not related to any great differences between the neural systems involved. It will be interesting to search for structures in the brain that differ in these two species and may be related to these two strategies. A particularly close connection between innate and ...
... typy are two close strategies and are not related to any great differences between the neural systems involved. It will be interesting to search for structures in the brain that differ in these two species and may be related to these two strategies. A particularly close connection between innate and ...
Genetic and Epigenetic Regulation in Age
... be significantly different. In addition, most current therapeutic drugs target to adjust the epigenome instead of changing the underlining DNA sequences in patients.56,57 Therefore, much attention has been given to studies of epigenetic regulations in AMD. Currently, molecular epigenetics studies the ...
... be significantly different. In addition, most current therapeutic drugs target to adjust the epigenome instead of changing the underlining DNA sequences in patients.56,57 Therefore, much attention has been given to studies of epigenetic regulations in AMD. Currently, molecular epigenetics studies the ...
A global test for groups of genes
... Study: 18 patients with UICC II colon cancer, 18 patients with UICC III colon cancer, HG-U133A, 22.283 probesets representing ~18.000 genes. Snap-frozen material, laser microdisection. Question 1: Is the differential gene expression between UICC II /III patients more distinct for genes in cancer rel ...
... Study: 18 patients with UICC II colon cancer, 18 patients with UICC III colon cancer, HG-U133A, 22.283 probesets representing ~18.000 genes. Snap-frozen material, laser microdisection. Question 1: Is the differential gene expression between UICC II /III patients more distinct for genes in cancer rel ...
Missing Value Estimation for Gene Expression Profile Data
... method for gene expression profile data is proposed by considering both the internal and external conditions of gene expression profiles. The internal condition emphasizes the time-series characteristic of gene expression profile data. Therefore, we can use the cubic spline fitting method to construct a ...
... method for gene expression profile data is proposed by considering both the internal and external conditions of gene expression profiles. The internal condition emphasizes the time-series characteristic of gene expression profile data. Therefore, we can use the cubic spline fitting method to construct a ...
BWS - Beckwith-Wiedemann Syndrome support
... imprinted. This means that either the maternal or the paternal copy should be active. In the next section we will see how errors on chromosome 11 are thought to be responsible for BWS. Causes of BWS The region of chromosome 11 involved in BWS is contains many genes. For simplicity we will concentrat ...
... imprinted. This means that either the maternal or the paternal copy should be active. In the next section we will see how errors on chromosome 11 are thought to be responsible for BWS. Causes of BWS The region of chromosome 11 involved in BWS is contains many genes. For simplicity we will concentrat ...
Pulling forces acting on Hox gene clusters cause expression
... biological facts which can reasonably reproduce the observed collinearity data (Papageorgiou, 2001; Papageorgiou, 2004). The guiding dogma in this pursuit is that what happens is what can happen: phenomena that have been observed in other occasions are adopted and applied in the present formulation ...
... biological facts which can reasonably reproduce the observed collinearity data (Papageorgiou, 2001; Papageorgiou, 2004). The guiding dogma in this pursuit is that what happens is what can happen: phenomena that have been observed in other occasions are adopted and applied in the present formulation ...
The osmZ
... in the external osmolarity triggers a rapid and large increase in pro U transcription, which is maintained for as long as the osmotic stimulus persists (Cairney et al. 1985; Dunlap and Csonka 1985; Gowrishankar 1985; Barron et al. 1986; May et al. 1986; Sutherland et al. 1986; Gutierrez et al. 1987) ...
... in the external osmolarity triggers a rapid and large increase in pro U transcription, which is maintained for as long as the osmotic stimulus persists (Cairney et al. 1985; Dunlap and Csonka 1985; Gowrishankar 1985; Barron et al. 1986; May et al. 1986; Sutherland et al. 1986; Gutierrez et al. 1987) ...
A programme for the construction of a lambda phage
... The genetic and physical map of the lambda chromosome (Fig. 1) shows marked clustering of genes of related function. The essential genes concerned with head (A-F) and tail (Z-7) formation and assembly are contiguous within the left-hand third of the genome. The region of the map between J and att, t ...
... The genetic and physical map of the lambda chromosome (Fig. 1) shows marked clustering of genes of related function. The essential genes concerned with head (A-F) and tail (Z-7) formation and assembly are contiguous within the left-hand third of the genome. The region of the map between J and att, t ...
PPT
... because not all genes are well annotated Further, Jenssen et al. (2001) earlier compiled a network of human gene relationships from MEDLINE abstracts. These compiled relationships were then compared to the gene expression cluster results. This approach gives a very interesting result: functionally r ...
... because not all genes are well annotated Further, Jenssen et al. (2001) earlier compiled a network of human gene relationships from MEDLINE abstracts. These compiled relationships were then compared to the gene expression cluster results. This approach gives a very interesting result: functionally r ...
portable document (.pdf) format
... et al. (2005) introduced a method called “cancer outlier profile analysis” (COPA) for detecting “oncogene outliers.” Those genes show systematically increased expressions in disease samples, but only for a small number of cancer samples. The outcome of the study shows that COPA can be more powerful ...
... et al. (2005) introduced a method called “cancer outlier profile analysis” (COPA) for detecting “oncogene outliers.” Those genes show systematically increased expressions in disease samples, but only for a small number of cancer samples. The outcome of the study shows that COPA can be more powerful ...
Examining the Process of de Novo Gene Birth
... For genes that arise from scratch, at some point in history there was a DNA sequence that was not a gene, and then that sequence somehow became a gene. Lest we begin to think in terms of magical transfiguration, it is worthwhile to consider what being a gene entails. First, genes are transcribed into ...
... For genes that arise from scratch, at some point in history there was a DNA sequence that was not a gene, and then that sequence somehow became a gene. Lest we begin to think in terms of magical transfiguration, it is worthwhile to consider what being a gene entails. First, genes are transcribed into ...
Eichenbaum et al., 2012a, #15 - Fortin Lab @ UCI
... A major challenge in the development of an animal model of episodic memory concerns the question of whether animals have this capacity and how to measure it. In humans, episodic memory is readily observed in the verbal recall of specific experiences, but this approach is obviously not possible in an ...
... A major challenge in the development of an animal model of episodic memory concerns the question of whether animals have this capacity and how to measure it. In humans, episodic memory is readily observed in the verbal recall of specific experiences, but this approach is obviously not possible in an ...
Molecular studies of major depressive disorder
... environment can have profound effects on the epigenetic profile of the genome, and that epigenetic marks can directly link environmental factors to gene function. Skewed X-chromosome inactivation is one X-linked epigenetic process that could potentially cause the excess rates of MDD in females, and ...
... environment can have profound effects on the epigenetic profile of the genome, and that epigenetic marks can directly link environmental factors to gene function. Skewed X-chromosome inactivation is one X-linked epigenetic process that could potentially cause the excess rates of MDD in females, and ...
Sex Determination using Polymerase Chain Reaction
... amplification [5]. Co-solvent and other additive like dimethyl sulfoxide and formamide also affect to the polymarase chain reaction [5]. In performing of the PCR, primer designing programs are very important [6]. Because of not proper designed prime cannot get the proper result. The most important a ...
... amplification [5]. Co-solvent and other additive like dimethyl sulfoxide and formamide also affect to the polymarase chain reaction [5]. In performing of the PCR, primer designing programs are very important [6]. Because of not proper designed prime cannot get the proper result. The most important a ...
Identification of Genetic Loci Associated With Helicobacter
... phenotype on the y-axis. Shown are the TLR (left) and FCGR2A (right) regions: purple diamonds indicate the top-ranked SNPs of the respective regions exhibiting the lowest P value for association with theMedical phenotype. The blue y-axes on the right of each plot Copyright © 2013 American Date of do ...
... phenotype on the y-axis. Shown are the TLR (left) and FCGR2A (right) regions: purple diamonds indicate the top-ranked SNPs of the respective regions exhibiting the lowest P value for association with theMedical phenotype. The blue y-axes on the right of each plot Copyright © 2013 American Date of do ...
12-Transcription-The Relationship Between Genes and Proteins
... • Eukaryotic genes may also have enhancers. • Enhancers can be located at great distances from the gene they regulate, either 5´ or 3´ of the transcription start, in introns or even on the noncoding strand. • One of the most common ways to identify promoters and enhancers is to use a reporter gene. ...
... • Eukaryotic genes may also have enhancers. • Enhancers can be located at great distances from the gene they regulate, either 5´ or 3´ of the transcription start, in introns or even on the noncoding strand. • One of the most common ways to identify promoters and enhancers is to use a reporter gene. ...
Searching for lost memories, Sudoku, and related ills of the brain
... generally confirm this name with complete confidence. Often when I try to recall a name, I first come up with a fragment, perhaps a feeling ‘sounds like Taylor’ without having the entire name yet available. If the name is required quickly, I may then even resort to going consciously through the alph ...
... generally confirm this name with complete confidence. Often when I try to recall a name, I first come up with a fragment, perhaps a feeling ‘sounds like Taylor’ without having the entire name yet available. If the name is required quickly, I may then even resort to going consciously through the alph ...