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Project 1 Concepts in Biology Project 1 Development of a PCR
Project 1 Concepts in Biology Project 1 Development of a PCR

... Mutations and Disease DNA is constantly subject to mutations, accidental changes in its code. Mutations can lead to missing or malformed proteins, and that can lead to disease. We all start out our lives with some mutations. These mutations inherited from your parents are called germ-line mutations. ...
Telophase 1 - Madeira City Schools
Telophase 1 - Madeira City Schools

... a. twice as many males as females have this. b. there is a region on the X chromosome that has many replications which elongates the X chromosome. Family history of Fragile X syndrome, especially a male relative Mental retardation Large testicles after puberty Large body size Tendency to avoid eye c ...
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dilemmas regarding clinical obligation

... detection in heterozygous cases such as these, conveying of this information, and how it is done requires careful education and explanation. We believe these three examples are likely to be representative of multiple additional genes where clinical interpretation of aCGH results needs to be carefull ...
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... natured family. You spend evenings searching the medical literature for potential treatments, including clinical trials, to help them. You remember learning about gene therapy trials for SCID (Severe Combined ImmunoDeficiency) and LCA (Leber’s Congenital Amaurosis—a type of hereditary blindness) in ...
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... 1B). The coefficient of variation (CV) with regard to yield was calculated for each donor; the values obtained were between 2.3% and 10.1%. DNA purity was high in all samples, with an average A260/A280 ratio of 1.91 (Figure 1A). The purified DNA was analyzed by agarose gel electrophoresis and by PCR ...
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... Figure 1. Co-expression of Cas9 and guide RNA in human cells generates double-strand DNA breaks at the target locus. (A) Top: schematic diagram of the Cas9-HA-NLS-GFP expression construct. Bottom: lysate from HEK293T cells transfected with the Cas9 expression plasmid was analyzed by Western blotting ...
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Gene expression profiling during conjugation of the Tetrahymena

Unlocking the healing power of stem cells
Unlocking the healing power of stem cells

... Pepper, working with a global research team, explores ways to help the human immune system to become HIV-resistant. This could have far-reaching implications in the management of the HIV/AIDS pandemic on the African continent. Gene-therapy research is done to create HIV-resistant blood-forming stem ...
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Vectors in gene therapy

Gene therapy utilizes the delivery of DNA into cells, which can be accomplished by several methods, summarized below. The two major classes of methods are those that use recombinant viruses (sometimes called biological nanoparticles or viral vectors) and those that use naked DNA or DNA complexes (non-viral methods).
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