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Biological membranes: the basics and why they are
Biological membranes: the basics and why they are

... and ‘inside’ (diffusion) • Keeps cell contents from leaking out and unwanted chemicals getting in • Evolved to permit and regulate the transfer of nutrients and waste products (channels) • Acquired the ability to achieve these functions against a concentration gradient (transporters) • Later develop ...
Genetics and Cancer Activity The cell cycle is controlled by a
Genetics and Cancer Activity The cell cycle is controlled by a

... The breast cancer 1 (BRCA1) gene has been implicated in breast cancer. Below is a pedigree of a family showing the incidence of breast cancer with a particular BRCA1allele. BRCA1+/BRCA1- females who have this particular allele of BRCA1- have a high chance of developing early onset breast cancer. Th ...
Silencing The
Silencing The

... “The ultimate goal is to tailor cancer therapy so that each patient will receive the optimal treatment based on their tumor’s specific epigenetic signature.” Unlike gene mutations, epigenetic “marks” are not permanent and in fact are reversible—a finding that has excited cancer researchers. A number ...
ANSWERS TO REVIEW QUESTIONS
ANSWERS TO REVIEW QUESTIONS

... Lethal alleles eliminate a progeny class that Mendel's laws predict should exist. Multiple alleles create the possibility of more than two phenotypic classes. Incomplete dominance introduces a third phenotype for a gene with two alleles. Codominance introduces a third phenotype for a gene with two a ...
pGLO Bacterial Transformation- Pre-Lab
pGLO Bacterial Transformation- Pre-Lab

... luciferase. Luciferins are oxidized in the presence of the enzyme luciferase to produce oxyluciferin and energy in the form of light. There are five general types of luciferins. Below is a list of the major luciferin types. ...
Mutation PPT
Mutation PPT

... frame (triplet grouping) of the gene • All the nucleotides that are downstream of the deletion or insertion will be improperly grouped into codons ...
Designer Babies & the government
Designer Babies & the government

... • In the future we may be able to "cure" genetic diseases in embryos by replacing faulty sections of DNA with healthy DNA. • This is called germ line therapy and is carried out on an egg, sperm or a tiny fertilized embryo. • Such therapy has successfully been done on animal embryos, • but at present ...
pGLO Bacterial Transformation- Pre-Lab
pGLO Bacterial Transformation- Pre-Lab

... luciferase. Luciferins are oxidized in the presence of the enzyme luciferase to produce oxyluciferin and energy in the form of light. There are five general types of luciferins. Below is a list of the major luciferin types. ...
Biology Standards Sheet
Biology Standards Sheet

... Performance Indicators: Students who demonstrate this understanding can: Ask questions to (1) generate hypotheses for scientific investigations, (2) refine models, explanations, or designs, or (3) extend the results of investigations or challenge scientific arguments or claims. Develop, use, and ref ...
Exam 1 - Faculty Web Pages
Exam 1 - Faculty Web Pages

... (a) This property is found in both prokaryotic cells and eukaryotic cells. (b) This property is found in prokaryotic cells. (c) This property is found in eukaryotic cells. (d) This property is found in viruses. 11. The ability to replicate by cell division. 12. Plasma membranes that contain speciali ...
Cellular Reproduction
Cellular Reproduction

... • Benign=mass that does not spread but can create obstructions, can be removed surgically. Look like normal cells • Malignant=cancer cells that spread and set up tumors elsewhere (Metastasis) – Metastasis cause unclear – One theory is a cancer WBC hybrid – Cells look different compared to a normal c ...
Introduction to sex determination
Introduction to sex determination

... Introduction to sex determination* Robert K. Herman§, Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, MN 55455 USA C. elegans has two sexes, hermaphrodite and male. The hermaphrodite is a modified female that in the fourth larval stage makes and stores sp ...
DNA and protein synthesis
DNA and protein synthesis

... With only a very few exception, every living cell contains DNA. (Red blood cells are one such exception.) In prokaryotic cells there may be just one DNA molecule. In eukaryotic cells there are usually several. For example, humans have 46 DNA molecules in their cells (when they are not dividing), bec ...
PCR (BASIC REQUIREMENT, copied from last semester lecture
PCR (BASIC REQUIREMENT, copied from last semester lecture

... fragments. PCR differs from PCR in that it is performed in vitro by DNA polymerase and not in living cells. The PCR technique was developed by Kary Mullis, who was awarded Nobel Prize in 1993. The following components are needed for the PCR. (1) DNA template containing the DNA fragment to be amplifi ...
Recombinant DNA Technology Biotechnology
Recombinant DNA Technology Biotechnology

... Significance of rDNA These proteins normally are produced in very small amounts or are synthesized at the wrong time in the human body  By being able to make these products in large amounts in other organisms, like bacteria. ...
Mutation - TeacherWeb
Mutation - TeacherWeb

... wrapped around histone protein which are tightly packed and organized •Chromatin makes up chromosomes 46 chromosomes (23 pairs) in humans ...
A Flexible Approach to Implement Genomic
A Flexible Approach to Implement Genomic

... Genome Sequencing Center (GSC) at Washington University, St. Louis, for use by students. Genomes enter the GSC as BAC or fosmid libraries from which clones to be sequenced are chosen. The GSC then prepares approximately 2 kb libraries from each clone that are then shotgun sequenced (Fig. 2). When th ...
HumanGenetics
HumanGenetics

... The result is that one gamete has 2 copies of one chromosome and the other has no copy of that chromosome. (The other chromosomes are distributed normally.) If either of these gametes unites with another during fertilization, the result is aneuploidy (abnormal chromosome number) A trisomic cell has ...
Competence
Competence

... - The radioactive DNA is then extracted and mixed with competent cells. - The mixture is treated with DNase at various times. - Any DNA that is not degraded and survives intact must have been taken up by the cells, where it is protected from the DNase. - Collect cells on filter and count the radioac ...
Types of DNA Mutations - Home
Types of DNA Mutations - Home

... DNA Repair Types ...
S1 Table.
S1 Table.

... skewed from a 50:50 allele ratio. In a pure tumor cell sample, the allele ratio would be shifted from 50:50 to 100:0, with complete loss of one allele. In angiomyolipoma and most other cancer types, there is admixture of normal cells in the tumor sample, such that the allele ratio might be 75:25 for ...
Soybean (Glycine max L.) Nuclear DNA Contains
Soybean (Glycine max L.) Nuclear DNA Contains

... Chloroplasts are considered to be endosymbionts of prokaryotic origin having invaded in an evolutionary past nucleated heterotrophic cells. During evolution parts of the. organellar genome were transposed to and successfully integrated in the nuclear genome ,i.e., structure and function of the photo ...
PASS study guide 2 - Cells_ Genetics_ Human Body
PASS study guide 2 - Cells_ Genetics_ Human Body

... expressed in the phenotype. Alleles for dominant traits are represented by capital letters; recessive traits – only expressed in the phenotype if two recessive alleles are present. Alleles for recessive traits are represented by lowercase letters Mutation - change in the genes of an organism. Many m ...
Snurfle Meiosis - sciencecounts2
Snurfle Meiosis - sciencecounts2

... 21. The homologous chromosomes split up and move toward the opposite ends of the cell during _____________. 22. ___________________________ independent cells begin to form during ___________________________ . 23. __________________________________ is the division of the cytoplasm to make two new cel ...
The Principle of Segregation
The Principle of Segregation

... dominant and one recessive allele b. Homozygous- combination of two of the same alleles - TT = Homozygous dominant - tt = Homozygous recessive Probability- the chance that a particular event will occur A. Each trait segregates independently so offspring have a 50/50 chance of inheritance (50% father ...
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Vectors in gene therapy

Gene therapy utilizes the delivery of DNA into cells, which can be accomplished by several methods, summarized below. The two major classes of methods are those that use recombinant viruses (sometimes called biological nanoparticles or viral vectors) and those that use naked DNA or DNA complexes (non-viral methods).
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