Nonrandom cell-cycle timing of a somatic chromosomal
... t(1;19)/der(19) clones and trisomy 1 have been observed in some cases. However, such a mechanism has less support in ASPS because cases with coexisting t(X;17)/der(17) clones or þX have not been reported. However, the caveat to this statement is that the total number of ASPS cases studied remains li ...
... t(1;19)/der(19) clones and trisomy 1 have been observed in some cases. However, such a mechanism has less support in ASPS because cases with coexisting t(X;17)/der(17) clones or þX have not been reported. However, the caveat to this statement is that the total number of ASPS cases studied remains li ...
A natural recessive resistance gene against potato virus
... and resistant pepper cultivars, using an eIF4E cDNA from tobacco as probe, revealed perfect map cosegregation between a polymorphism in the eIF4E gene and the pvr2 alleles, pvr21 (resistant to PVY-0) and pvr2 2 (resistant to PVY-0 and 1). The cloned pepper eIF4E cDNA encoded a 228 amino acid polypep ...
... and resistant pepper cultivars, using an eIF4E cDNA from tobacco as probe, revealed perfect map cosegregation between a polymorphism in the eIF4E gene and the pvr2 alleles, pvr21 (resistant to PVY-0) and pvr2 2 (resistant to PVY-0 and 1). The cloned pepper eIF4E cDNA encoded a 228 amino acid polypep ...
PcGs and Hox genes - Development
... et al., 1995; Justice et al., 1995). This phenotype is not observed for clones of any of the other PcG mutants. We find that in the absence of Psc-Su(z)2 or ph function, imaginal disc cells are larger than wild-type cells (data not shown) but additional studies will be needed to establish how cell g ...
... et al., 1995; Justice et al., 1995). This phenotype is not observed for clones of any of the other PcG mutants. We find that in the absence of Psc-Su(z)2 or ph function, imaginal disc cells are larger than wild-type cells (data not shown) but additional studies will be needed to establish how cell g ...
Unicellular Eukaryotes to Humans Protein Arginine
... Npl3, Hrp1, and Nab2 is perturbed in PRMT1-null cells (34, 85). Subsequent studies with humans showed that PRMT1 affects the subcellular localization of a number of PRMT1 substrates (21, 66, 89). Additional insights into the biological role of PRMT1 have recently been obtained from genomewide studie ...
... Npl3, Hrp1, and Nab2 is perturbed in PRMT1-null cells (34, 85). Subsequent studies with humans showed that PRMT1 affects the subcellular localization of a number of PRMT1 substrates (21, 66, 89). Additional insights into the biological role of PRMT1 have recently been obtained from genomewide studie ...
Targeted Therapies in Cancer
... of proteins. Some of the proteins may be involved in the cancer process, whereas others may be byproducts. Both proteins may help predict which patients will or will not respond to a certain treatment. However, drugs that target the by-product may not actually treat the cancer, whereas drugs that ta ...
... of proteins. Some of the proteins may be involved in the cancer process, whereas others may be byproducts. Both proteins may help predict which patients will or will not respond to a certain treatment. However, drugs that target the by-product may not actually treat the cancer, whereas drugs that ta ...
Three-letter Symbols - Online Open Genetics
... have their cell membranes modified by sugar tags that give rise to our blood type. One allele of I gives rise to blood type A and is therefore called IA. An enzyme encoded by IB modifies sugars to create blood type B. A heterozygote IAIB demonstrates both sugar tags because those alleles are express ...
... have their cell membranes modified by sugar tags that give rise to our blood type. One allele of I gives rise to blood type A and is therefore called IA. An enzyme encoded by IB modifies sugars to create blood type B. A heterozygote IAIB demonstrates both sugar tags because those alleles are express ...
7nQ Jj I f NO "7^07 - UNT Digital Library
... insights to DNA and disorders both common and rare. Recombinant DNA technology is changing everyday, offering new ways to cope with many of the disorders that affect humans. There are ways to incorporate gene therapy today that were not available even five years ago. Along with this new knowledge, c ...
... insights to DNA and disorders both common and rare. Recombinant DNA technology is changing everyday, offering new ways to cope with many of the disorders that affect humans. There are ways to incorporate gene therapy today that were not available even five years ago. Along with this new knowledge, c ...
Gene7-05
... 1. Genetic information carried by DNA is expressed in two stages: transcription of DNA into mRNA; and translation of the mRNA into protein. 2. The adaptor that interprets the meaning of a codon is transfer RNA, which has a compact L-shaped tertiary structure 3. The ribosome provides the apparatus th ...
... 1. Genetic information carried by DNA is expressed in two stages: transcription of DNA into mRNA; and translation of the mRNA into protein. 2. The adaptor that interprets the meaning of a codon is transfer RNA, which has a compact L-shaped tertiary structure 3. The ribosome provides the apparatus th ...
Accounting for Non-Genetic Factors Improves the Power of eQTL
... other physiological and biological factors. In principle, when collecting gene expression data sets for eQTL, non-genetic factors should be controlled to be constant across all samples, but in practice this can only be achieved to a limited degree. Indeed, it is reasonable to expect that a substanti ...
... other physiological and biological factors. In principle, when collecting gene expression data sets for eQTL, non-genetic factors should be controlled to be constant across all samples, but in practice this can only be achieved to a limited degree. Indeed, it is reasonable to expect that a substanti ...
Sickle solubility test - United Laboratories Company
... The kits for sickle cell solubility tests that are predominantly used in the UK will detect haemoglobin S down to a concentration of 20% (and sometimes below; in some cases as low as 8%) (BCSH 1998). The methods are therefore capable of detecting all cases of sickle cell trait beyond the period of i ...
... The kits for sickle cell solubility tests that are predominantly used in the UK will detect haemoglobin S down to a concentration of 20% (and sometimes below; in some cases as low as 8%) (BCSH 1998). The methods are therefore capable of detecting all cases of sickle cell trait beyond the period of i ...
c-myc Driven by the Proto-Oncogene B Lymphocyte Commitment
... genes, conferring B cell identity on early lymphoid precursors (7). E2A-deficient pro-B cells are rescued by ectopic expression of EBF-1 in vitro but not by Pax-5 (8). Inactivation of pax-5 in mice causes a block in early B cell differentiation (9) and impaired Vdistal-to-DHJH rearrangement (10). Pa ...
... genes, conferring B cell identity on early lymphoid precursors (7). E2A-deficient pro-B cells are rescued by ectopic expression of EBF-1 in vitro but not by Pax-5 (8). Inactivation of pax-5 in mice causes a block in early B cell differentiation (9) and impaired Vdistal-to-DHJH rearrangement (10). Pa ...
Importance of integrons in the diffusion of resistance
... The principal mechanisms facilitating horizontal gene transfer among bacteria are transformation, transduction and conjugation. Transformation involves the uptake and incorporation of naked DNA, which may become available in the environment following bacterial autolysis. This source of genetic mater ...
... The principal mechanisms facilitating horizontal gene transfer among bacteria are transformation, transduction and conjugation. Transformation involves the uptake and incorporation of naked DNA, which may become available in the environment following bacterial autolysis. This source of genetic mater ...
Page 517 Duplication of the S. cerevisiae genome
... of just several million years (Lynch and Conery, 2000). 50% to 92% of duplicated genes are lost (Wagner, 2001) Consider four possible fates of a duplicated gene: [1] Both copies persist (gene dosage effect) [2] One copy is deleted (a common fate) [3] One copy accumulates mutations and becomes a pseu ...
... of just several million years (Lynch and Conery, 2000). 50% to 92% of duplicated genes are lost (Wagner, 2001) Consider four possible fates of a duplicated gene: [1] Both copies persist (gene dosage effect) [2] One copy is deleted (a common fate) [3] One copy accumulates mutations and becomes a pseu ...
A virulence-associated gene microarray: a tool for
... contributed by virulence-associated genes (Fitzgerald et al., 2001). This ensures that strains present a variable antigenic profile to the host and may limit the effective immunity of the population to colonization. S. aureus strains carry a range of genes that confer resistance to a growing list of ...
... contributed by virulence-associated genes (Fitzgerald et al., 2001). This ensures that strains present a variable antigenic profile to the host and may limit the effective immunity of the population to colonization. S. aureus strains carry a range of genes that confer resistance to a growing list of ...
Molecular characterization of dioxygenases from polycyclic aromatic
... residues and one aspartate residue, which according to Parales et al. [6] bind the mononuclear iron, as well as one aspartate residue proposed to play an important role in electron transfer to mononuclear iron [6] were conserved (alignment not shown). According to high sequence similarity to M. vanb ...
... residues and one aspartate residue, which according to Parales et al. [6] bind the mononuclear iron, as well as one aspartate residue proposed to play an important role in electron transfer to mononuclear iron [6] were conserved (alignment not shown). According to high sequence similarity to M. vanb ...
S - www2
... quantitative information on sedimentation velocity from a preparative ultracentrifuge is the disturbance of the material distribution by turbulence from physical vibrations or due to convection from thermal differences in different parts of the tube. This is partly overcome by the use of a sucrose g ...
... quantitative information on sedimentation velocity from a preparative ultracentrifuge is the disturbance of the material distribution by turbulence from physical vibrations or due to convection from thermal differences in different parts of the tube. This is partly overcome by the use of a sucrose g ...
November 2012 - University of Hartford`s Academic Web Server
... two nukes + a ritonavir-boosted protease inhibitor two nukes + an integrase inhibitor When starting therapy for the first time, one of these combinations is usually prescribed. Among treatment-experienced patients, sometimes more complex regimens are used. One type of simplification Standard ART is ...
... two nukes + a ritonavir-boosted protease inhibitor two nukes + an integrase inhibitor When starting therapy for the first time, one of these combinations is usually prescribed. Among treatment-experienced patients, sometimes more complex regimens are used. One type of simplification Standard ART is ...
Chapter 6 – Exam style questions Q1. Bk Ch6 Exam MQ1 What is
... A mutation is a change in the genetic make-up of an individual. Beadle and Tatum subjected the bread mould Neurospora crassa to X-rays to produce mutated strains. Each of the mutated strains lacked the ability to manufacture an amino acid or vitamin that was needed for normal growth. They were able ...
... A mutation is a change in the genetic make-up of an individual. Beadle and Tatum subjected the bread mould Neurospora crassa to X-rays to produce mutated strains. Each of the mutated strains lacked the ability to manufacture an amino acid or vitamin that was needed for normal growth. They were able ...
Figure 15 - GEP Community Server
... Download tool, we are ready to search for motifs that are enriched in this collection of sequences. Among the plethora of motif discovery tools that are publicly available, the MEME suite is one of the most popular solutions (BAILEY et al. 2009). In this walkthrough, we will use the web-based MEME i ...
... Download tool, we are ready to search for motifs that are enriched in this collection of sequences. Among the plethora of motif discovery tools that are publicly available, the MEME suite is one of the most popular solutions (BAILEY et al. 2009). In this walkthrough, we will use the web-based MEME i ...
Gene Expression in Thyroxin-Induced Metamorphosing Axolotl Hearts
... The Mexican axolotl (Ambystoma mexicanum) is a unique model to study vertebrate heart development for several reasons. In addition to the wild-type animal, there is also an embryonic lethal condition caused by a homozygous recessive mutation in cardiac gene “c” [1,2]. These mutant embryonic hearts d ...
... The Mexican axolotl (Ambystoma mexicanum) is a unique model to study vertebrate heart development for several reasons. In addition to the wild-type animal, there is also an embryonic lethal condition caused by a homozygous recessive mutation in cardiac gene “c” [1,2]. These mutant embryonic hearts d ...
• 100 times faster than dynamic programming. • Good for database
... – The E-value decreases exponentially as the Score (S) that is assigned to a match between two sequences increases. – The E-value depends on the size of database and the scoring system in use use. – When the E-value threshold is increased from the default value of 10, more hits can be reported. When ...
... – The E-value decreases exponentially as the Score (S) that is assigned to a match between two sequences increases. – The E-value depends on the size of database and the scoring system in use use. – When the E-value threshold is increased from the default value of 10, more hits can be reported. When ...
Probing chromatin-modifying enzymes with chemical tools Wolfgang
... SAM (Figure 2c). It was shown that the PMT can utilize 5‘-(diaminobutyric acid)-N-iodoethyl-5‘deoxyadenosine ammonium hydrochloride (AAI, 3) for labeling a histone H4 peptide containing the target arginine 3 residue. The reaction progresses via an aziridinium ion (4) as intermediate, in which the s ...
... SAM (Figure 2c). It was shown that the PMT can utilize 5‘-(diaminobutyric acid)-N-iodoethyl-5‘deoxyadenosine ammonium hydrochloride (AAI, 3) for labeling a histone H4 peptide containing the target arginine 3 residue. The reaction progresses via an aziridinium ion (4) as intermediate, in which the s ...
mthfr - SpectraCell Laboratories
... • 5-Methyl-THF slows the rate of FAD release in both the wild-type and mutant enzymes. • Mutations in the MTHFR gene could be one of the factors leading to increased risk of developing chronic diseases and psychiatric problems. “Effects of the methylenetetrahydrofolate reductase (MTHFR) C677T polymo ...
... • 5-Methyl-THF slows the rate of FAD release in both the wild-type and mutant enzymes. • Mutations in the MTHFR gene could be one of the factors leading to increased risk of developing chronic diseases and psychiatric problems. “Effects of the methylenetetrahydrofolate reductase (MTHFR) C677T polymo ...
Rice Bioinformatics. Analysis of Rice Sequence Data and
... Rice (Oryza sativa) is a model species for monocotyledonous plants, especially for members in the grass family. Several attributes such as small genome size, diploid nature, transformability, and establishment of genetic and molecular resources make it a tractable organism for plant biologists. With ...
... Rice (Oryza sativa) is a model species for monocotyledonous plants, especially for members in the grass family. Several attributes such as small genome size, diploid nature, transformability, and establishment of genetic and molecular resources make it a tractable organism for plant biologists. With ...